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    Process for the preparation of amine-oxidase containing material, so produced amine-oxidase containing material
    41.
    发明授权
    Process for the preparation of amine-oxidase containing material, so produced amine-oxidase containing material 失效
    制备含有胺氧化酶的材料的方法，因此制得含胺氧化酶的材料

    公开(公告)号：US4725540A

    公开(公告)日：1988-02-16

    申请号：US750877

    申请日：1985-07-01

    申请人： Emil Underberg ,  Andreas Lembke

    发明人： Emil Underberg ,  Andreas Lembke

    IPC分类号： A23K10/10 ,  A23L5/20 ,  C12H1/00 ,  C12H1/15 ,  C12N9/06 ,  C12P39/00 ,  A23K1/00 ,  C12G1/00 ,  C12R1/225 ,  C12R1/72

    CPC分类号： C12N9/0022 ,  A23K10/10 ,  A23L5/25 ,  C12H1/003 ,  C12P39/00 ,  Y10S435/853 ,  Y10S435/921

    摘要： A process for the preparation of histaminase, respectively a histaminase containing material, is described. Histaminase is a diamine-oxidase which metabolizes histamine.According to the process at least one microorganism which produces in its cells histaminase, is cultivated and as soon as a sufficient number of microorganisms has grown, the microorganisms are isolated from the culture medium. Adhering culture medium is removed from the microorganisms and the microorganism cells are broken up and comminuted.The product can be dried in the vacuum, cooled and stored or it can be used to produce products having a higher content of histaminase or to produce a pure histaminase.Preferably a mixture of microorganisms is cultivated which contains at least one microorganism selected from the group lactobacillus and at least one yeast selected from the group candida.The histaminase containing products, respectively the histaminase, are used for metabolizing histamine in foodstuffs, beverages and forages yielding corresponding histamine free products in which the histamine had been metabolized forming not harmful metabolization products.

    摘要翻译： 描述了组胺酶的制备方法，分别是含有组胺酶的材料。 组氨酸酶是代谢组胺的二胺氧化酶。 根据该方法，至少一种在其细胞中产生组氨酸酶的微生物被培养，并且一旦有足够数量的微生物生长，则从培养基中分离微生物。 将粘附培养基从微生物中除去，并将微生物细胞分解并粉碎。 产物可以在真空中干燥，冷却和储存，或者可以用于生产具有较高含量的组胺酶的产物或产生纯的组胺酶。 优选培养含有至少一种选自乳酸杆菌和选自念珠菌属的酵母的微生物的混合物。 含有组氨酸酶的产品分别为组胺酶，用于代谢食物，饮料和饲料中的组胺，产生相应的不含组胺的产品，其中组胺被代谢形成不是有害的代谢产物。