Compound having thiol anchoring group, method of synthesizing the same, and molecular electronic device having molecular active layer formed using the compound
    41.
    发明授权
    Compound having thiol anchoring group, method of synthesizing the same, and molecular electronic device having molecular active layer formed using the compound 失效
    具有硫醇锚定基团的化合物,其合成方法和使用该化合物形成分子活性层的分子电子器件

    公开(公告)号:US07538199B2

    公开(公告)日:2009-05-26

    申请号:US11398188

    申请日:2006-04-04

    IPC分类号: C07C245/02

    CPC分类号: C07D417/12 C07D333/42

    摘要: Provided are an electron donor-azo-electron acceptor compound having a thiol-based anchoring group, a method of synthesizing the compound, and a molecular electronic device having a molecular active layer formed of the compound. The compound for forming a molecular electronic device includes an azo compound that has a dinitrothiophene group and an aminobenzene group having thiol derivatives. The compound forms a molecular active layer in the molecular electronic devices. The molecular active layer is self-assembled on an electrode using the thiol derivative in the azo compound as an anchoring group. The molecular active layer in the molecular electronic device forms a switching device switching between an on-state and an off-state in response to a voltage applied to electrodes or a memory device storing a predetermined electric signal in response to a voltage applied to the electrodes.

    摘要翻译: 提供具有硫醇基锚定基团的电子给体 - 偶氮电子受体化合物,合成该化合物的方法和具有由该化合物形成的分子活性层的分子电子器件。 用于形成分子电子器件的化合物包括具有二硝基噻吩基团和具有硫醇衍生物的氨基苯基团的偶氮化合物。 该化合物在分子电子器件中形成分子活性层。 使用偶氮化合物中的硫醇衍生物作为锚定基团,在电极上自组装分子活性层。 分子电子器件中的分子活性层响应于施加到电极的电压或存储预定电信号的存储器件响应于施加到电极的电压而形成在导通状态和截止状态之间切换的开关器件 。

    Whole cell assay involving cathepsin s
    42.
    发明申请
    Whole cell assay involving cathepsin s 审中-公开
    全细胞检测涉及组织蛋白酶

    公开(公告)号:US20070026477A1

    公开(公告)日:2007-02-01

    申请号:US10571016

    申请日:2004-09-17

    IPC分类号: C12Q1/48 C07C245/02

    摘要: The present invention relates to a method of identifying and evaluating chemical inhibitors of cathepsin S activity in whole cells. The present invention also relates to probes that are capable of forming irreversible adducts with cathepsin S at the active site. The probes used in the instant invention comprise radioactive functional groups to allow the detection of the irreversible cathepsin S-probe adducts.

    摘要翻译: 本发明涉及鉴定和评估整个细胞中组织蛋白酶S活性的化学抑制剂的方法。 本发明还涉及能够在活性部位与组织蛋白酶S形成不可逆加合物的探针。 用于本发明的探针包括放射性官能团,以允许检测不可逆的组织蛋白酶S-探针加合物。

    Method of colouring porous material
    43.
    发明申请
    Method of colouring porous material 失效
    多孔材料着色方法

    公开(公告)号:US20050251932A1

    公开(公告)日:2005-11-17

    申请号:US10525300

    申请日:2003-08-26

    摘要: A method of colouring porous material, especially human hair, is described, which method comprises applying to the material being coloured, in any desired order successively, or simultaneously, a) at least one capped diazonium compound of Formula (1) and/or at least one compound of Formula (2) and/or at least one compound of Formula (3) wherein Q is an unsubstituted or substituted aromatic or heterocyclic residue, R is the radical of an unsubstituted or substituted, water-soluble aliphatic or aromatic amine, and T is an unsubstituted or substituted, water-soluble aliphatic or aromatic residue, wherein at least one of the groups must contain a radical imparting water solubility, and a) at least one water-soluble coupling component under conditions such that, initially, coupling does not take place, and then causing the capped diazonium compound present on the material to react with the coupling component.

    摘要翻译: 描述了一种着色多孔材料,特别是人发的方法,该方法包括以任何所需顺序依次或同时施用着色的材料,a)至少一种式(1)的封端重氮化合物和/或在 至少一种式(2)的化合物和/或至少一种式(3)的化合物,其中Q是未取代或取代的芳族或杂环残基,R是未取代或取代的水溶性脂族或芳族胺的基团, 并且T是未取代或取代的水溶性脂族或芳族残基,其中所述基团中的至少一个必须含有自由基赋予水溶性,和a)至少一种水溶性偶联组分, 不会发生,然后使存在于材料上的覆盖的重氮化合物与偶联组分反应。

    Organic photoconductive material and a photosensitive material for
electronic photography using it
    47.
    发明授权
    Organic photoconductive material and a photosensitive material for electronic photography using it 失效
    有机光电导材料和使用它的电子摄影用感光材料

    公开(公告)号:US5569749A

    公开(公告)日:1996-10-29

    申请号:US588091

    申请日:1996-01-18

    摘要: An organic photoconductive material is represented by the following general formula [1]:A.sub.1 --N.dbd.N--B--N.dbd.N--A.sub.2 [1],wherein B is a divalent organic group bonded to nitrogen atoms forming azo groups, A.sub.1 and A.sub.2 are groups different from each other, A.sub.1 is represented by the following general formula [A1]: ##STR1## wherein X is an atomic group which is necessary for forming an aromatic hydrocarbon ring or an aromatic hetero-ring by condensation with the benzene ring, Y is a hydrogen atom, an alkyl group, an alkoxy group or a halogen atom, m is an integer of 1 to 4, R is an aromatic hydrocarbon ring group or an aromatic hetero-ring group and n is 1 or 2, and A.sub.2 is a group represented by one of the following general formulae [A2] and [A3]: ##STR2## wherein a.sub.1 is a group selected from R, --N.dbd.CH--R and ##STR3## R, X, Y, m and n are the same as those in the general formula [A1] and p is 0 or 1. A photosensitive material for electronic photography having excellent properties, such as charging property, retention of charge, sensitivity, residual voltage and image formation, and showing no change of the properties after repeated use for a long time can be obtained by using an azo compound having a specific structure as the carrier generating substance. A photosensitive material for electric photography of a laminate type or a dispersion type having high performance and high durability can also be provided.

    摘要翻译: 有机光电导材料由以下通式[1]表示:A1-N = NBN = N-A2 [1],其中B是与氮原子键合形成偶氮基的二价有机基团,A1和A2是不同于 彼此相同,A1由以下通式[A1]表示:通过与苯环缩合形成芳香族烃环或芳香族杂环,Y为氢原子,烷基,烷氧基或烷氧基, 卤素原子,m为1〜4的整数,R为芳香族烃环基或芳香族杂环基,n为1或2,A2为下述通式[A2]所示的基团, 和[A3]: [A2] [A3]其中a1是选自R,-N = CH-R和 R,X,Y,m和n中的基团与 在通式[A1]中,p为0或1.用于电子照相的感光材料具有优异的性能,例如带电性,电荷保留性,敏感性 通过使用具有特定结构的偶氮化合物作为载体生成物质,可以获得长时间重复使用后的特性,残留电压和图像形成,并且不显示出特性变化。 也可以提供具有高性能和高耐久性的层压型或分散型电摄影用感光材料。

    Organic photoconductive material and a photosensitive material for
electronic photography using it
    48.
    发明授权
    Organic photoconductive material and a photosensitive material for electronic photography using it 失效
    有机光导材料和使用它的电子摄影用感光材料

    公开(公告)号:US5506346A

    公开(公告)日:1996-04-09

    申请号:US202355

    申请日:1994-02-28

    摘要: An organic photoconductive material is represented by the following general formula [1]:A.sub.1 -N.dbd.N-B-N.dbd.N-A.sub.2 [1],wherein B is a divalent organic group bonded to nitrogen atoms forming azo groups, A.sub.1 and A.sub.2 are groups different from each other, A.sub.1 is represented by the following general formula [A1]: ##STR1## wherein X is an atomic group which is necessary for forming an aromatic hydrocarbon ring or an aromatic hetero-ring by condensation with the benzene ring, Y is a hydrogen atom, an alkyl group, an alkoxy group or a halogen atom, m is an integer of 1 to 4, R is an aromatic hydrocarbon ring group or an aromatic hetero-ring group and n is 1 or 2, and A.sub.2 is a group represented by one of the following general formulae [A2] and [A3]: ##STR2## wherein a.sub.1 is a group selected from R, -N.dbd.CH-R and ##STR3## R, X, Y, m and n are the same as those in the general formula [A1] and p is 0 or 1. A photosensitive material electronic photography having excellent properties, such as charging property, retention of charge, sensitivity, residual voltage and image formation, and showing no change of the properties afar repeated use for a long time can be obtained by using an azo compound having a specific structure as the carrier generating substance. A photosensitive material for electric photography of a laminate type or a dispersion having high performance and high durability can also be provided.

    摘要翻译: 有机光电导材料由以下通式[1]表示:A1-N = NBN = N-A2 [1],其中B是与氮原子键合形成偶氮基的二价有机基团,A1和A2是不同于 另外,A1由以下通式[A1]表示:其中,X是通过与苯环缩合形成芳香族烃环或芳香族杂环所必需的原子团,Y 是氢原子,烷基,烷氧基或卤素原子,m是1〜4的整数,R是芳香族烃环基或芳香族杂环基,n是1或2,A2是 由下列通式[A2]和[A3]之一表示的基团:其中a1是选自R,-N = CH-R和 R的基团 X,Y,m和n与通式[A1]中的相同,p为0或1.具有优异性能的感光材料电子照相如炭 通过使用具有特定结构的偶氮化合物作为载体生成物质,可以获得长时间的性能,保持电荷,灵敏度,残余电压和图像形成,并且不会长时间反复使用的性质的变化。 还可以提供具有高性能和高耐久性的层压型或分散体的电摄影用感光材料。

    Compounds which release nitric oxide upon illumination
    49.
    发明授权
    Compounds which release nitric oxide upon illumination 失效
    照射时释放一氧化氮的化合物

    公开(公告)号:US5374710A

    公开(公告)日:1994-12-20

    申请号:US67657

    申请日:1993-05-26

    CPC分类号: C07C291/08

    摘要: Chemical derivatives of nitric oxide are provided which are stable indefinitely in oxygen-containing solutions until photolysis, whereupon they release NO. These compounds have the general formulaA--N.sup.+ (O.sup.-)=N--O--B (I)wherein A is typically a nitrogen- or oxygen-containing substituent and B is a group lablie to photolysis. The compounds are stable and inert in oxygenated aqueous solutions, but release NO upon illumination. Given the ease with which the intensity, timing and location of illumination may be controlled, these compounds are particularly useful in investigating the biological effects of NO with much higher spatial or temporal resolution than heretofore possible.

    摘要翻译: 提供一氧化氮的化学衍生物,其在含氧溶液中无限制地稳定直至光解,于是它们释放NO。 这些化合物具有通式A-N +(O - )= N-O-B(I)其中A通常是含氮或含氧取代基,B是不溶于光解的基团。 化合物在氧化水溶液中是稳定的和惰性的,但在照射时释放NO。 鉴于可以轻松控制照明的强度,时间和位置,这些化合物特别适用于调查NO的生物效应,空间或时间分辨率比以前更高。