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889 条记录 (耗时 0.04 秒)

    Means and Methods for Generating Complex Glycans Derived From Fungal Engineered Hosts
    51.
    发明申请
    Means and Methods for Generating Complex Glycans Derived From Fungal Engineered Hosts 有权

    公开(公告)号：US20210292796A1

    公开(公告)日：2021-09-23

    申请号：US17186609

    申请日：2021-02-26

    申请人： VIB VZW ,  UNIVERSITEIT GENT

    发明人： Nico L.M. Callewaert ,  Bram Laukens

    IPC分类号： C12P1/02 ,  C12P21/00 ,  A61K38/17

    摘要： The present application relates to the field of glyco-engineering, more specifically to glycosylation-engineered fungal cells, more specifically glycosylation-engineered yeast cells, optimized to produce highly homogenous forms of complex N-glycans on recombinant proteins. The invention specifically relates to methods to obtain pharmaceutical compositions comprising recombinant glycoproteins which have homogenous forms of complex N-glycans. In addition, the invention relates to novel pharmaceutical compositions which result from the methods of the invention.

    NANOSTRUCTURED SHAPES HAVING ANISOTROPIC ABSORPTION AND EMISSION
    52.
    发明申请
    NANOSTRUCTURED SHAPES HAVING ANISOTROPIC ABSORPTION AND EMISSION 有权

    公开(公告)号：US20210249546A1

    公开(公告)日：2021-08-12

    申请号：US17251672

    申请日：2019-06-17

    申请人： Universiteit Gent

    发明人： Kristiaan Neyts ,  Yerzhan Ussembayev

    IPC分类号： H01L31/0352 ,  C09K11/88 ,  H01L31/055 ,  H01L31/0296 ,  H01L31/18 ,  G02F1/1335 ,  G02B5/30

    摘要： Nanostructured shapes comprising at least a first part and a second part. The first part has a longitudinal axis L and comprises a first absorbing material and an emitting material. The second part is connected to the first part and comprises a second absorbing material. The second part mainly absorbs light with direction of polarization other than the long axis L of the first part, and the nanostructured shape emits light mainly polarized along the long axis L of the first part. The disclosure further relates to an assembly of nanostructured shapes, to a method of synthesizing nanostructured shapes and to a polarizing light emitting plate comprising such nanostructured shapes.

    THERMOHYDRAULIC AND BIOLOGIC MODEL-BASED CONTROL
    54.
    发明申请
    THERMOHYDRAULIC AND BIOLOGIC MODEL-BASED CONTROL 有权

    公开(公告)号：US20210215352A1

    公开(公告)日：2021-07-15

    申请号：US17054778

    申请日：2019-05-16

    申请人： Universiteit Gent

    发明人： Elisa van Kerkhove ,  Jelle Laverge

    IPC分类号： F24D17/00 ,  G06F30/28

    摘要： A control unit (100, 120, 130) adapted to regulate at least one de-bacterisation unit (201) of a fluid system (200, 210, 230) is described. The fluid system (200, 210, 230) comprises the de-bacterisation unit, a production unit for producing a heated fluid heated to a predetermined temperature, at least one pipe for transporting the fluid from the production unit to at least one fluid outlet, at least one fluid outlet and at least one sensing unit for sensing a temperature of the fluid at a first location in the fluid system as a function of time. The control unit (100, 120, 130) includes a module (101, 124) adapted for obtaining temperatures at a plurality of locations in the fluid system as function of time and programmed for modelling bacterial growth in the fluid in the fluid system as function of time based on the obtained temperature in the system and for predicting, based on the modelling, the bacterial concentration at the at least one fluid outlet over time. The control unit is being adapted for driving the de-bacterisation unit, The control unit is being adapted for determining, based on said predicted bacterial concentration over time obtained by the module (101, 124), moments in time when the bacterial concentration reaches a predetermined value in the fluid system and for, in reply thereto, driving at these moments in time the de-bacterisation unit (201) so as to reduce bacterial concentration in the fluid system (200, 210, 230).

    FREEZING, DRYING AND/OR FREEZE-DRYING OF PRODUCT DOSE UNITS
    56.
    发明申请
    FREEZING, DRYING AND/OR FREEZE-DRYING OF PRODUCT DOSE UNITS 有权

    公开(公告)号：US20210190424A1

    公开(公告)日：2021-06-24

    申请号：US17252681

    申请日：2019-06-28

    申请人： UNIVERSITEIT GENT

    发明人： Thomas DE BEER ,  Jozef Antonius Willem Maria CORVER ,  Brecht VANBILLEMONT ,  Jean Paul REMON

    IPC分类号： F26B5/06 ,  F25B21/02 ,  F26B5/04 ,  F26B25/14 ,  F26B25/18 ,  F26B25/22

    摘要： A device for holding and monitoring a predetermined dose of a product during a freezing, drying and/or lyophilization process, includes a mold having a receptacle part for containing the predetermined dose of the product in direct contact with the receptacle part, a sensor, contacting the mold or integrated in the mold, for measuring a physical characteristic and/or quantity, and a transmitter for transmitting the measured characteristic and/or quantity in the form of a sensor signal to a control unit for controlling a heating and/or cooling element, integrated in the device, for heating and/or cooling a predetermined dose of product during a freezing, drying and/or lyophilization process, in the lyophilization process. The device relates in further aspects to a system and a method.

    DIFFERENTIAL TRANSIMPEDANCE AMPLIFIER
    59.
    发明申请
    DIFFERENTIAL TRANSIMPEDANCE AMPLIFIER 有权

    公开(公告)号：US20210126594A1

    公开(公告)日：2021-04-29

    申请号：US16981864

    申请日：2019-03-20

    申请人： UNIVERSITEIT GENT ,  IMEC VZW

    发明人： Joris LAMBRECHT ,  Hannes RAMON ,  Bart MOENECLAEY ,  Xin YIN

    IPC分类号： H03F3/08 ,  H03F1/08 ,  H03F3/45 ,  H03G3/30

    摘要： A transimpedance amplifier is provided for converting a current between its two input terminals to a voltage over its two output terminals comprising a high-speed level shifter configured for creating a difference in input DC voltage and for being transparent for alternating voltages, an input biasing network configured for reverse biasing a photodiode connected to at least one of the input terminals and transparent for a feedback signal from the feedback network which is differentially and DC-coupled with the output terminals of the voltage amplifier and outputs of the feedback network are differentially and DC-coupled with the input biasing network of which outputs are coupled with inputs of the level shifter which is differentially and DC-coupled with input terminals of the voltage amplifier.

    NOVEL MUTANT PLANT CINNAMOYL-CoA REDUCTASE PROTEINS
    60.
    发明申请
    NOVEL MUTANT PLANT CINNAMOYL-CoA REDUCTASE PROTEINS 有权

    公开(公告)号：US20210115462A1

    公开(公告)日：2021-04-22

    申请号：US16972290

    申请日：2019-06-06

    申请人： VIB VZW ,  UNIVERSITEIT GENT

    发明人： Wout Boerjan ,  Barbara De Meester ,  Ruben Vanholme

    IPC分类号： C12N15/82 ,  C12N9/02

    摘要： The present invention relates to a mutant plant Cinnamoyl-CoA Reductase (CCR) protein capable of restoring the yield penalty in plants with lignin traits such as ccr-related deficiencies and methods and uses thereof. More specifically, the invention relates to plants lacking functional wild type CCR protein but having a weak ccr allele resulting in lower lignin amounts and increased saccharification, further accompanied by plant growth restoration of the lignin modification-induced dwarfism.