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    A METHOD TO DEINK AND/OR TO DELAMINATE PLASTIC MATERIAL USING AN AMINE
    1.
    发明申请
    A METHOD TO DEINK AND/OR TO DELAMINATE PLASTIC MATERIAL USING AN AMINE 有权

    公开(公告)号：US20250059344A1

    公开(公告)日：2025-02-20

    申请号：US18719927

    申请日：2022-12-16

    Applicant: UNIVERSITEIT GENT

    Inventor： Steven DE MEESTER ,  Sibel ÜGDÜLER ,  Martijn ROOSEN

    IPC: C08J11/28

    Abstract: The invention relates to a method to deink and/or to delaminate plastic material, preferably to a method to deink and delaminate plastic material in a single step. The method comprises the step of contacting the plastic material with an amine or a composition comprising said amine, wherein the amine comprises a nitrogen atom having at least one hydrocarbon substituent comprising an acyclic or cyclic alkyl group. The total number of carbon atoms of all hydrocarbon substituents of the nitrogen atom is at least (5).

    CLOCK AND DATA RECOVERY
    2.
    发明申请
    CLOCK AND DATA RECOVERY 有权

    公开(公告)号：US20250055669A1

    公开(公告)日：2025-02-13

    申请号：US18801077

    申请日：2024-08-12

    Applicant: IMEC VZW ,  Universiteit Gent

    Inventor： Marijn VERBEKE

    IPC: H04L7/033 ,  H04L7/00

    Abstract: A method and a circuitry to perform clock and data recovery, CDR is provided. The method includes the steps of obtaining an analogue communication signal characterized by a symbol frequency Fsymbol; and performing an analogue-to-digital conversion of the analogue communication signal according to a sampling rate Fsample targeting Fsymbol*(M/L) thereby obtaining a digital signal. The method includes up-sampling the digital signal by L; filtering the up-sampled digital signal with filter coefficients of a finite impulse response, FIR, filter to perform a fractionally-spaced equalisation; and down-sampling the filtered digital signal by M resulting in a recovered digital signal. Intermediate filter coefficients are obtained for the FIR filter and a phase error is determined based on the recovered digital signal. The intermediate filter coefficients are interpolated based on the phase error to compensate for the phase error, resulting in interpolated filter coefficients; and the filter coefficients of the FIR filter are updated with the interpolated filter coefficients.

    METHODS FOR REGIOSELECTIVE FUNCTIONALIZING A SURFACE OF AN ELECTRON MICROSCOPY GRID
    4.
    发明申请
    METHODS FOR REGIOSELECTIVE FUNCTIONALIZING A SURFACE OF AN ELECTRON MICROSCOPY GRID 有权

    公开(公告)号：US20250037963A1

    公开(公告)日：2025-01-30

    申请号：US18715495

    申请日：2022-12-01

    Applicant: UNIVERSITEIT GENT ,  IMEC VZW

    Inventor： Wouter VAN PUTTE ,  Thomas REICHERT

    IPC: H01J37/20

    Abstract: The invention provides a method for regioselective functionalizing a surface of an electron microscopy grid (10), therefore: a) providing a surface (20) of an electron microscopy grid (101); b) providing a plurality of wall systems (30A, 30B) on the surface of an electron microscopy grid, thereby forming a plurality of temporary reaction chambers (40A, 40B); c) providing a modification solution (50) in each temporary reaction chambers (40A, 40B); d) modifying the parts of the surface (21A, 21B) in the temporary reaction chambers (40A, 40B) with the modification solution(s) (50, 50A, 50B); e) removing the modification solution(s) (50, 50A, 50B) from the temporary reaction chambers (40A, 40B); f) removing the plurality of wall systems (30A, 30B) from the surface (20). The invention further provides in an electron microscopy grid to be regioselective functionalised and an apparatus for regioselective functionalizing a surface of an electron microscopy grids.

    HAFNIUM (IV) OXIDE NANOPARTICLES AND AQUEOUS COMPOSITIONS THEREOF
    5.
    发明申请
    HAFNIUM (IV) OXIDE NANOPARTICLES AND AQUEOUS COMPOSITIONS THEREOF 有权

    公开(公告)号：US20250018067A1

    公开(公告)日：2025-01-16

    申请号：US18711699

    申请日：2022-11-23

    Applicant: UNIVERSITÄT BASEL ,  UNIVERSITEIT GENT

    Inventor： Loren DEBLOCK ,  Jonathan DE ROO

    IPC: A61K49/04 ,  A61K9/51 ,  A61K47/54

    Abstract: The invention relates to a hafnium (IV) oxide (HfO2) nanoparticle nanocrystal comprising or having a diameter equal or less than (≤) 15 nm, stabilized by a plurality of dispersant molecules attached to its surface. The dispersant molecules comprise of a catechol or gallol surface adsorption moiety and an oligo (ethyleneglycol) moiety. The invention further relates to a composition of such nanoparticles in stable colloidal suspension at physiological pH, and the use of the composition in medical treatment and diagnostic applications, particularly to enhance radiotherapy and as an X ray contrast agent. In yet another aspect, the invention provides a method for manufacturing compositions and nanoparticles according to the invention.

    PROFILING CIRCUITRY
    6.
    发明申请
    PROFILING CIRCUITRY 有权

    公开(公告)号：US20250013471A1

    公开(公告)日：2025-01-09

    申请号：US18694318

    申请日：2022-09-23

    Applicant: Norwegian University of Science and Technology (NTNU) ,  Universiteit Gent

    Inventor： Magnus Jahre ,  Björn Gottschall ,  Lieven Eeckhout

    IPC: G06F9/38 ,  G06F9/30

    Abstract: Profiling circuitry for a processor includes state-determining circuitry that is configured to access information stored by the processor for committing inflight instructions in program order, and to use this information to determine a commit state of the processor. The profiling circuitry also has sampling circuitry which is configured, when the processor is in a first commit state, to output sample data to a sample register or a memory that identifies one or more instructions that are next to be committed by the processor, and, when the processor is in a second commit state, to output sample data to the sample register or memory that identifies an instruction that was last committed by the processor.

    Overload clutch with joint torque and disengagement sensing
    7.
    发明申请
    Overload clutch with joint torque and disengagement sensing 有权

    公开(公告)号：US20240401649A1

    公开(公告)日：2024-12-05

    申请号：US18702369

    申请日：2022-09-23

    Applicant: UNIVERSITEIT GENT

    Inventor： Frederik Leopold A Ostyn

    IPC: F16D7/02 ,  F16D7/04

    Abstract: An overload clutch comprising an input flange and an output flange, said clutch being configured to transmit torque between the input flange and the output flange and to disengage the clutch when the torque exceeds a predetermined threshold, characterised in, that the clutch comprises one or more sensing means at least partially integrated in at least one of the input and output flanges, and that the one or more sensing means are adapted to jointly determine the torque applied to transmitted between the input flange and the output flange of the clutch and to detect the disengagement of the clutch. A device comprising the clutch, a gear unit connected to the input flange, and a motor connected to the gear unit, configured to provide torque to the input flange through the gear unit.

    Cation-Independent Mannose-6-Phosphate Receptor Binders For Targeted Protein Degradation
    8.
    发明公开
    Cation-Independent Mannose-6-Phosphate Receptor Binders For Targeted Protein Degradation 审中-公开

    公开(公告)号：US20240327525A1

    公开(公告)日：2024-10-03

    申请号：US18293467

    申请日：2022-07-29

    Applicant: VIB VZW ,  Universiteit Gent

    Inventor： Nico Callewaert ,  Justine Naessens ,  Linde Van Landuyt

    IPC: C07K16/28 ,  A61K39/00 ,  C07K16/46

    CPC classification number: C07K16/2863 ,  C07K16/468 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/565 ,  C07K2317/569 ,  C07K2317/77 ,  C07K2317/92

    Abstract: The present invention relates to protein binding agents specifically binding the human cation-independent mannose-6-phosphate receptor (CI-M6PR), more specifically polypeptide agents comprising an immunoglobulin single variable domain (ISVD) specifically binding CI-M6PR at nano- to picomolar affinity, fused to further protein binding agents specifically binding extracellularly-accessible protein targets, such as membrane proteins, extracellular or secreted proteins. More specifically said CI-M6PR-specific ISVD recognizes CI-M6PR N-terminal domains 1, 2 and/or 3, thereby providing for means and methods for internalization, lysosomal targeting and degradation of agents comprising said ISVD, and of targets bound to said protein binding agents. The CI-M6PR binders disclosed herein are thus linked or fused to a further protein binding agent, in particular another antigen-binding protein, such as an ISVD or antibody, relevant for use in therapy, more specifically for treatment of diseases affected by said target antigen bound by said antigen-binding protein. More specifically disclosed herein are CI-M6PR ISVD fusions to antigen-binding proteins specifically binding EGFR, for treatment of cancer.

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