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公开(公告)号：US20230152287A1
公开(公告)日：2023-05-18
申请号：US17794767
申请日：2020-07-18
Inventor： Zejian Wang , Daqi Gao , Xiaoqin Zhang , Bo Li , Fang Cai , Jianhua Li , Mingjian Cheng
Abstract: Provided is an electronic nose instrument based on gas sensitivity and gas chromatography and an online analysis method of multiple state parameters of fermentation and malodorous pollutant processes. The main constituent units of the instrument include a gas sensor array module, a capillary gas chromatographic column module, an automatic gas sampling module, and a computer control and analysis module. A single gas sampling period is T0=300-600s. Not only are two flow rates and two accumulative volumes of gas sampling unequal to each other, but also two starting time points are not synchronized to each other, between the gas sensor array module and the gas chromatography module. 3 pieces of sensitive information, i.e., a steady-state peak value, a corresponding peak time value and an area under a whole curve, are selected from a response curve of a single gas sensor with a 60s duration by the computer control and analysis module, or 48 pieces of gas sensitive information in total, and 21 pieces of sensitive information, i.e., 10 maximum peak values, 10 corresponding retention time values, and 1 area under the whole chromatographic curve, are selected from a semi-separation chromatogram with a duration T0−10 s. Furthermore, the cyclical online identification and intensity and quantitative estimation of multiple indices of odors for five fermentation or malodorous pollution processes with a maximum cyclical gas sampling period T=5T0 are realized by a modular deep convolutional neural network model according to a 69-dimensional normalized fused real-time sensitive pattern and an existing big odor data.
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公开(公告)号：US20230103274A9
公开(公告)日：2023-03-30
申请号：US17421929
申请日：2019-10-31
Inventor： Runzi Wang , Xiancheng Zhang , Sujuan Guo , Guangjian Yuan , Xumin Zhu , Shantung Tu
Abstract: The present invention discloses a multiaxial creep-fatigue prediction method based on ABAQUS, which comprises: S1: establishing an ABAQUS finite element model, and defining the viscoplastic constitutive equation of the material to be tested by means of the user subroutine UMAT; S2: determining the model parameters required by the viscoplastic constitutive equation; S3: establishing the fatigue damage calculation model and creep damage calculation model of the multiaxial stress-strain state of the material to be tested; S4: establishing an ABAQUS finite element model under the multiaxial stress-strain state, and calculating the stress-strain tensor of each cycle based on the defined viscoplastic constitutive equation and the model parameters; S5: calculating the equivalent stress and equivalent plastic strain by means of the user subroutine USDFLD, and superimposing the fatigue damage and creep damage of each cycle according to the linear cumulative damage criterion to obtain the crack initiation life of the material to be tested based on the fatigue damage calculation model and creep damage calculation model in combination with the stress-strain tensor.
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公开(公告)号：US20230102416A1
公开(公告)日：2023-03-30
申请号：US17563421
申请日：2021-12-28
Inventor： Yanqin WANG , Wanjun GUO , Shuang XIANG , Xiaohui LIU , Yong GUO
IPC: B01J23/75 , C07C209/78 , B01J35/00 , B01J37/18 , B01J37/03 , B01J37/08 , B01J23/83 , B01J23/882 , B01J23/78
Abstract: Disclosed is a method for efficiently synthesizing primary amines, which comprises using carbonyl compounds or alcohol compounds as reaction substrate, liquid ammonia or alcohol solutions of ammonia as nitrogen source, and hydrogen as hydrogen source, and reacting in reaction medium catalyzed by a cobalt-based catalyst to obtain the primary amines. Due to high catalytic activity, the method can realize the reductive amination of carbonyl compounds and the hydrogen-borrowing amination of alcohol compounds at low temperatures in a short time to obtain the primary amines with high yield, and is applicable to a wide range of substrates. The obtained primary amines can be used as raw materials with high extra value for producing polymers, medicines, dyes and surfactants. Further, the cobalt-based catalyst has a good industrial application prospect because it is magnetic which can facilitate separation and recycling of the catalyst. Moreover, the inexpensive cobalt-based catalyst can significantly reduce industrialization cost.
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公开(公告)号：US20230002769A1
公开(公告)日：2023-01-05
申请号：US17607102
申请日：2020-04-28
Inventor： Yi YANG , Linyong ZHU , Xianjun CHEN , Dasheng ZHANG , Ni SU , Qiuning LIN
IPC: C12N15/115 , C07C255/58 , C12Q1/6876 , C12N15/10 , C07C255/53 , C07D241/20 , C07D213/74 , C07D239/42 , C07D213/85 , C07D241/24 , C07D263/56 , C07D277/64 , C07D333/60 , C07D495/04 , C09K11/06
Abstract: The present application relates to an aptamer nucleic acid molecule, a complex containing the aptamer nucleic acid molecules, a method of detecting intracellular or extracellular RNA, DNA or other target molecules, and a kit containing the aptamer. The aptamer of the present application is capable of specifically binding a kind of fluorophore micromolecules, and can significantly enhance fluorescence intensity under excitation light of appropriate wavelength.
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55.发明申请公开(公告)号：US20220301661A1
公开(公告)日：2022-09-22
申请号：US17631080
申请日：2020-12-02
Inventor： Wenli DU , Minglei YANG , Weimin ZHONG , Feng QIAN , Zhi LI
Abstract: A method and system for predicting products of an aromatic hydrocarbon isomerization production process are provided. The method includes generating multiple initial sample points, using a mechanism the actual output response values of all of the initial sample points; establishing an radial basis function (RBF) model according to the initial sample points and actual output response values thereof; using a particle swarm optimization (PSO) algorithm to find expected deviation between nearest neighbors as well as the sampling point having the largest sparsity product, using mechanism model to calculate the output response value of said sampling point on RBF model, adding output response value into the sample points, and reconstructing the surrogate model; repeating the previous step until the upper limit for the number of sample points is reached to obtain a final RBF model; and using the RBF model to predict product yield of aromatic hydrocarbon isomerization.
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Patent Agency Ranking
公开(公告)号：US20220275282A1
公开(公告)日：2022-09-01
申请号：US17627824
申请日：2020-06-16
Inventor： Yulong CHANG , Hualin WANG , Xia JIANG , Jianping LI , Jingyi ZHU , Pengbo FU , Wei YUAN
IPC: C10G3/00
Abstract: A method and apparatus for hydrocracking mineralized refuse pyrolysis oil. The method may use the following steps: (a) crushing and pyrolyzing mineralized refuse to obtain arene and alkane precursor biomass oil; (b) hydrogenating the arene and alkane precursor biomass oil obtained in step (a), and separating the obtained hydrocrackate to obtain arene and alkane; and (c) purifying, recovering and optimizing the arene and alkane obtained in step (b), and performing deep processing to produce naphtha, jet fuel, light diesel oil, and heavy diesel oil.
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公开(公告)号：US20220226539A1
公开(公告)日：2022-07-21
申请号：US17199835
申请日：2021-03-12
Inventor： Yuan YUAN , Haoyi NIU , Hua HONG , Yongsheng LI , Lili SUN
Abstract: The present disclosure relates to a composite scaffold containing DFO and rhBMP-2 capable of synergistically stimulating bone formation, a preparation method and use thereof. The composite scaffold contains a matrix, a PEGS gel layer and rhBMP-2, wherein the matrix is an MBG scaffold grafted with DFO on the surface, the PEGS gel layer is carried on the surface of the matrix, and rhBMP-2 is carried inside the PEGS gel layer. In the present disclosure, the function of DFO and rhBMP-2 in vivo and in vitro can be regulated by precisely controlling the immobilization mode and spatial distribution of DFO and rhBMP-2 in the scaffold, and the all-round repair of “rapid enrichment of target cells—angiogenesis-guided bone” can be achieved.
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58.发明授权公开(公告)号：US11384036B2
公开(公告)日：2022-07-12
申请号：US17403321
申请日：2021-08-16
Inventor： Yanqin Wang , Yaxuan Jing , Yong Guo , Xiaohui Liu , Ning Yan
Abstract: Disclosed is a method for preparing aromatic hydrocarbons by hydrocracking a polymer containing aromatic rings, which includes reacting the polymer fragment with hydrogen under the action of a catalyst at a temperature of no more than 350° C.; separating a reaction product to obtain the aromatic hydrocarbons. The catalyst comprises a carrier and an active ingredient supported on the carrier, the active ingredient is at least one selected from Ru, Rh, Pt, Pd, Fe, Ni, Cu and Co, the carrier is at least one selected from metal oxide, phosphate, molecular sieve, SiO2 and sulfonated carbon, the metal oxide is at least one selected from Al2O3, Nb2O5, Nb2O5—Al2O3, Nb2O5—SiO2, TiO2, ZrO2, CeO2 and MoO3; the phosphate is at least one selected from NbOPO4 and ZrOPO4; and the molecule sieve is at least one selected from Nb-SBA-15, Nafion, H-ZSM-5, H-Beta and H-Y.
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公开(公告)号：US11320353B2
公开(公告)日：2022-05-03
申请号：US17286567
申请日：2019-10-10
Inventor： Fuzhen Xuan , Tianye Niu , Jianguo Gong
Abstract: A creep strength analysis and assessment method includes comparing whether a maximum value of a local strain and a membrane strain are less than a corresponding allowable strain, and if less, determining that a component is safe; otherwise, performing the following steps: performing stress linearization on a path to obtain a local primary membrane stress PL and a local primary bending stress Pb; averaging shear stress components on the path to obtain an average shear stress τm; obtaining a strength limit Smt, a time-independent minimum stress strength value Sm and a temperature- and time-dependent stress strength limit St for a given material, a design lifetime and a design temperature; comparing whether PL, PL+Pb and PL+Pb/Kt are less than Smt, KSm and St; and comparing whether τm is less than 0.6Sm and 0.6St, and if less, the component is safe, otherwise, the component is unsafe.
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公开(公告)号：US20210341365A1
公开(公告)日：2021-11-04
申请号：US17286567
申请日：2019-10-10
Inventor： Fuzhen Xuan , Tianye Niu , Jianguo Gong
Abstract: A creep strength analysis and assessment method includes comparing whether a maximum value of a local strain and a membrane strain are less than a corresponding allowable strain, and if less, determining that a component is safe; otherwise, performing the following steps: performing stress linearization on a path to obtain a local primary membrane stress PL and a local primary bending stress Pb; averaging shear stress components on the path to obtain an average shear stress τm; obtaining a strength limit Smt, a time-independent minimum stress strength value Sm and a temperature- and time-dependent stress strength limit St for a given material, a design lifetime and a design temperature; comparing whether PL, PL+Pb and PL+Pb/Kt are less than Smt, KSm and St; and comparing whether τm is less than 0.6Sm and 0.6St, and if less, the component is safe, otherwise, the component is unsafe.
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