Aminobenzoic acid derivatives having anti-tumorigenic activity methods of making and using the same
    51.
    发明授权
    Aminobenzoic acid derivatives having anti-tumorigenic activity methods of making and using the same 有权
    具有抗致瘤活性的氨基苯甲酸衍生物的制备和使用方法

    公开(公告)号:US06294695B1

    公开(公告)日:2001-09-25

    申请号:US09258732

    申请日:1999-02-26

    IPC分类号: C07C23728

    CPC分类号: C07C275/54

    摘要: Haloacetoamido, benzoic acid derivatives having anti-tumorigenic activity are inclosed. Examples of the haloacetoamido, benzoic acid derivatives include 3-chloroacetoamido, benzoylurca, 3-bromoacctoamido, benzoylurea, 3-todoacetoamido, benzoylurca, ethyl-3-chloroacetoamido, benzoate, ethyl-3-bromoacetoamido, benzoate and ethyl-3-iodoacetoamido, benzoate. Intermediates for synthesizing the derivatives, along with method of making and using the derivatives, are also provided.

    摘要翻译: 卤代乙酰胺,具有抗致瘤活性的苯甲酸衍生物被封闭。 卤代乙酰氨基,苯甲酸衍生物的实例包括3-氯乙酰氨基,苯甲酰脲,3-溴代酰胺基,苯甲酰脲,3-甲氧基乙酰氨基,苯甲酰脲,乙基-3-氯乙酰胺基,苯甲酸乙酯,3-溴代乙酰氨基乙酰胺,苯甲酸乙酯和3-碘乙酰氨基乙酰胺, 。 还提供了用于合成衍生物的中间体以及制备和使用衍生物的方法。

    Method and Compositions for Treatment or Prevention of Inflammatory Conditions
    53.
    发明申请
    Method and Compositions for Treatment or Prevention of Inflammatory Conditions 有权
    治疗或预防炎症病症的方法和组成

    公开(公告)号:US20140296273A1

    公开(公告)日:2014-10-02

    申请号:US14191219

    申请日:2014-02-26

    IPC分类号: A61K31/4375

    摘要: Pharmaceutical compositions and methods for treating or preventing an inflammatory condition in a patient are disclosed. The pharmaceutical compositions and methods include the use of vincamine or a vincamine derivative, either alone or in combination with one or more additional therapeutic agents, including a steroid (preferably a corticosteroid), an angiotensin II receptor (type 1) antagonist, an angiotensin-converting enzyme (ACE) inhibitor, and a non-steroidal anti-inflammatory drug.

    摘要翻译: 公开了用于治疗或预防患者炎症状况的药物组合物和方法。 药物组合物和方法包括使用长春胺或长春胺衍生物,单独或与一种或多种另外的治疗剂组合使用,包括类固醇(优选皮质类固醇),血管紧张素II受体(1型)拮抗剂,血管紧张素 - 转化酶(ACE)抑制剂和非甾体抗炎药。

    Feedwells
    56.
    发明授权
    Feedwells 有权
    饲料

    公开(公告)号:US08540887B2

    公开(公告)日:2013-09-24

    申请号:US12992869

    申请日:2009-04-30

    IPC分类号: B01D21/24

    CPC分类号: B01D21/2411 B01D21/2427

    摘要: The invention provides several improvements in feedwells, one of which being a feedwell (100) comprising a mixing zone (49) for dissipating the kinetic energy of a fluid comprising pulp, a settling zone (50) for promoting flocculation of the pulp and at least one inclined deflecting element (101) for at least partially separating the mixing zone from the settling zone. Other improvements include a shelf (3) at least partially defining an inclined path (4) for removing material from the shelf into a feedwell chamber; at least two outlets (111, 112) arranged in a substantially concentric relationship with respect to each other; a portion (123) of a second conduit (121) varies in its cross-sectional size and/or shape so as to connect a feed inlet (110) to a first conduit (120); and a partition (133) for partially separating an outer mixing zone (131) and an inner settling zone (132).

    摘要翻译: 本发明提供了进料口的几个改进,其中一个是供料口(100),其包括用于耗散包含纸浆的流体的动能的混合区(49),用于促进纸浆絮凝的沉降区(50) 一个倾斜偏转元件(101),用于至少部分地将混合区域与沉降区域分开。 其他改进包括至少部分地限定用于将材料从搁板移走到进料井室中的倾斜路径(4)的搁架(3) 至少两个出口(111,112)相对于彼此以基本上同心的关系布置; 第二导管(121)的一部分(123)以其横截面尺寸和/或形状变化,以将进料入口(110)连接到第一导管(120); 以及用于部分分离外部混合区域(131)和内部沉降区域(132)的隔板(133)。

    METHODS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CARDIAC REMODELING AND HEART FAILURE
    57.
    发明申请
    METHODS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CARDIAC REMODELING AND HEART FAILURE 审中-公开
    治疗或预防心律失常重塑和心脏衰竭的方法和组合

    公开(公告)号:US20110190373A1

    公开(公告)日:2011-08-04

    申请号:US12991345

    申请日:2009-05-05

    申请人: Chen Yan Jian-Dong Li

    发明人: Chen Yan Jian-Dong Li

    CPC分类号: A61K31/4745

    摘要: The invention relates to methods of treating or preventing pathological cardiac remodeling and/or preventing heart failure. These methods include the administration of a PDE1 inhibitor to a patient under conditions effective to treat or prevent pathological cardiac remodeling, and therefore heart failure that occurs as a result of such remodeling. Pharmaceutical compositions and delivery vehicles that can be used in the methods of the present invention are also disclosed herein.

    摘要翻译: 本发明涉及治疗或预防病理性心脏重塑和/或预防心力衰竭的方法。 这些方法包括在有效治疗或预防病理性心脏重塑的病症下向患者施用PDE1抑制剂,因此由于这种重塑而发生的心力衰竭。 可用于本发明方法的药物组合物和递送载体也在本文中公开。

    Method of volume-panorama imaging processing
    58.
    发明授权
    Method of volume-panorama imaging processing 有权
    体积全景成像处理方法

    公开(公告)号:US07844130B2

    公开(公告)日:2010-11-30

    申请号:US12506980

    申请日:2009-07-21

    IPC分类号: G06K9/36

    摘要: The present invention discloses a method of volume-panorama imaging processing, which generates a volume-panorama image by subsequently splicing respective image frames from an image sequence obtained in a real-time way or stored in a medium based upon the fact that the immediately adjacent image frames have the largest correlation. The method comprises the steps of: reading the image sequence, and firstly initializing an aligned image and a spliced image; dividing the i-th image frame Fi into a plurality of sub-regions; calculating a motion vector of the i-t image frame with respect to the aligned image; fitting the motion vector to calculate a transform coefficient; splicing the Fi to the current spliced image based upon the transform coefficient, and updating the aligned image; entering into a self-adaptive selection of a next image frame until the end of the splicing; and outputting the current spliced image as a resultant image. Additionally, when the image Fi is spliced, double-filtering architecture of selecting characteristic points through a filtering and selecting the valid motion vector of the selected characteristic points through the other filtering to reduce an alignment error may be adopted. According to the present invention, the volume-panorama imaging can be done quickly and accurately so that the reliability of images particularly meets a very high requirement of the ultrasonic iatric diagnose.

    摘要翻译: 本发明公开了一种体积全景成像处理的方法,其通过随后从实时方式获得的图像序列中拼接各个图像帧或存储在介质中来生成体积全景图像,其基于紧邻的 图像帧具有最大的相关性。 该方法包括以下步骤:读取图像序列,首先初始化对准的图像和拼接图像; 将第i图像帧F i划分成多个子区域; 计算i-t图像帧相对于对准图像的运动矢量; 拟合运动矢量以计算变换系数; 基于变换系数将Fi拼接到当前拼接图像,并更新对准的图像; 进入下一个图像帧的自适应选择直到拼接结束; 并输出当前拼接图像作为合成图像。 此外,当图像Fi被拼接时,可以采用通过滤波选择特征点的双重滤波架构,并且通过另一滤波选择所选特征点的有效运动矢量以减少对准误差。 根据本发明,可以快速准确地进行体积全景成像,使得图像的可靠性特别满足超声波诊断的非常高的要求。

    Electronic device and rotating mechanism
    59.
    发明授权
    Electronic device and rotating mechanism 失效
    电子设备和旋转机构

    公开(公告)号:US07801578B2

    公开(公告)日:2010-09-21

    申请号:US11934866

    申请日:2007-11-05

    IPC分类号: H04M1/00

    CPC分类号: H04M1/0216

    摘要: An electronic device and a rotating mechanism thereof are provided. The electronic device includes a first casing, a second casing, and a rotating mechanism. The first casing has a first receiving space and a first hole disposed a first side thereof, wherein the first receiving space is intercommunicated with the first hole. The second casing has a second receiving space and a second hole disposed a second side thereof, wherein the second receiving space is intercommunicated with the second hole. The rotating mechanism includes a shaft, a first fixing element and a second fixing element. The shaft has a center axis, wherein part of the shaft is received in the first receiving space and part of the shaft is received in the second receiving space, such that the first casing can be rotated around the center axis with respect to the second casing.

    摘要翻译: 提供电子装置及其旋转机构。 电子设备包括第一壳体,第二壳体和旋转机构。 第一壳体具有第一容纳空间和设置在其第一侧的第一孔,其中第一容纳空间与第一孔相互连通。 第二壳体具有第二容纳空间和设置在其第二侧的第二孔,其中第二容纳空间与第二孔相通。 旋转机构包括轴,第一固定元件和第二固定元件。 所述轴具有中心轴线,其中所述轴的一部分被容纳在所述第一容纳空间中,并且所述轴的一部分被容纳在所述第二容纳空间中,使得所述第一壳体可相对于所述第二壳体绕所述中心轴线旋转 。