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    METHOD AND APPARATUS FOR ULTRASONIC IMAGING IN MMODE
    3.
    发明申请
    METHOD AND APPARATUS FOR ULTRASONIC IMAGING IN MMODE 有权
    用于超声波成像的方法和装置

    公开(公告)号：US20090214093A1

    公开(公告)日：2009-08-27

    申请号：US12432533

    申请日：2009-04-29

    申请人： Bin YAO ,  Jian DONG ,  Yong LI

    发明人： Bin YAO ,  Jian DONG ,  Yong LI

    IPC分类号： G06K9/00

    CPC分类号： A61B8/08 ,  A61B8/0883 ,  A61B8/461 ,  A61B8/486 ,  Y10S128/922

    摘要： An mmode imaging method and apparatus for an ultrasonic diagnostic device is provided to increase the continuity of displayed mmode images. An mmode imaging method performed by an ultrasonic diagnosis device selects sample points on frames of bmode images, converts bmode data of the sample points obtained from the frames of bmode images into converted mmode data, produces interpolated mmode data based on the echo data of corresponding sample points on at least two different frames, and images at least a portion of the mmode data in time sequence.

    摘要翻译： 提供了一种用于超声波诊断装置的毫米成像方法和装置，以增加显示的mmode图像的连续性。 由超声波诊断装置执行的mmode成像方法选择bmode图像的帧上的采样点，将从bmode图像的帧获得的采样点的bmode数据转换为转换的mmode数据，基于相应样本的回波数据产生内插的mmode数据 指向至少两个不同的帧，并且以时间顺序图像至少一部分mmode数据。

    Method of using ryanodine receptor antagonists to treat amyotrophic lateral sclerosis
    5.
    发明申请
    Method of using ryanodine receptor antagonists to treat amyotrophic lateral sclerosis 审中-公开
    使用兰诺定受体拮抗剂治疗肌萎缩性侧索硬化的方法

    公开(公告)号：US20070049630A1

    公开(公告)日：2007-03-01

    申请号：US11448555

    申请日：2006-06-07

    申请人： Cun-Jian Dong ,  William Hare

    发明人： Cun-Jian Dong ,  William Hare

    IPC分类号： A61K31/13 ,  A61K31/4178

    CPC分类号： A61K45/06 ,  A61K31/00 ,  A61K31/13 ,  A61K31/4178 ,  A61K2300/00

    摘要： The present invention provides a method of providing neural protection in in human patients suffering from amyotrophic lateral sclerosis comprising administering to said patients suffering from said amyotrophic lateral sclerosis an effective amount of a compound that is a ryanodine receptor antagonist in pharmaceutically acceptable vehicle to inhibit or prevent neuronal njury or death.

    摘要翻译： 本发明提供在患有肌萎缩性侧索硬化症的人类患者中提供神经保护的方法，包括对所述患有肌萎缩性侧索硬化症的患者施用有效量的药学上可接受的媒介物中的兰诺定受体拮抗剂的化合物以抑制或预防 神经元损伤或死亡。

    Method of volume-panorama imaging processing
    7.
    发明申请
    Method of volume-panorama imaging processing 有权
    体积全景成像处理方法

    公开(公告)号：US20060239571A1

    公开(公告)日：2006-10-26

    申请号：US11316440

    申请日：2005-12-22

    申请人： Jian Dong ,  Dong Ni ,  Bin Yao

    发明人： Jian Dong ,  Dong Ni ,  Bin Yao

    IPC分类号： G06K9/36

    CPC分类号： G06K9/32 ,  G06K2009/2045 ,  G06T7/238 ,  G06T7/32 ,  G06T7/33 ,  G06T2207/10132 ,  G06T2207/20021 ,  G06T2207/30004

    摘要： The present invention discloses a method of volume-panorama imaging processing, which generates a volume-panorama image by subsequently splicing respective image frames from an image sequence obtained in a real-time way or stored in a medium based upon the fact that the immediately adjacent image frames have the largest correlation. The method comprises the steps of: reading the image sequence, and firstly initializing an aligned image and a spliced image; dividing the i-th image frame Fi into a plurality of sub-regions; calculating a motion vector of the i-t image frame with respect to the aligned image; fitting the motion vector to calculate a transform coefficient; splicing the Fi to the current spliced image based upon the transform coefficient, and updating the aligned image; entering into a self-adaptive selection of a next image frame until the end of the splicing; and outputting the current spliced image as a resultant image. Additionally, when the image Fi is spliced, double-filtering architecture of selecting characteristic points through a filtering and selecting the valid motion vector of the selected characteristic points through the other filtering to reduce an alignment error may be adopted. According to the present invention, the volume-panorama imaging can be done quickly and accurately so that the reliability of images particularly meets a very high requirement of the ultrasonic iatric diagnose.

    摘要翻译： 本发明公开了一种体积全景成像处理的方法，其通过随后从实时方式获得的图像序列中拼接各个图像帧或存储在介质中来生成体积全景图像，其基于紧邻的 图像帧具有最大的相关性。 该方法包括以下步骤：读取图像序列，首先初始化对准的图像和拼接图像; 将第i个图像帧F SUB分割成多个子区域; 计算i-t图像帧相对于对准图像的运动矢量; 拟合运动矢量以计算变换系数; 基于所述变换系数将所述拼接图像拼接到所述拼接图像上，更新所述对准图像; 进入下一个图像帧的自适应选择直到剪接结束; 并输出当前拼接图像作为合成图像。 另外，当拼接图像F i时，通过滤波选择特征点的双重滤波结构，并且通过另一滤波选择所选特征点的有效运动矢量以减少对准误差可以是 通过了 根据本发明，可以快速准确地进行体积全景成像，使得图像的可靠性特别满足超声波诊断的非常高的要求。

    Low cost high fidelity service load generator for random vibration simulation tests
    9.
    发明申请
    Low cost high fidelity service load generator for random vibration simulation tests 有权
    低成本高保真服务负载发生器，用于随机振动模拟测试

    公开(公告)号：US20050060134A1

    公开(公告)日：2005-03-17

    申请号：US10662065

    申请日：2003-09-15

    申请人： Jian Dong

    发明人： Jian Dong

    IPC分类号： G06F9/45 ,  G06F17/50

    CPC分类号： G06F17/5095 ,  G06F17/5009

    摘要： An easy and cost-effective method of generating high fidelity simulation service loads. This invention, however, provides a simple but theoretically sound approach to conducting an accelerated simulation test, while obtaining a reasonable acceleration rate for the test. By developing a service load history database; Combining multiple time series models; Adjusting the change of each time series model creating an accelerated service load model; regenerating a random vibration load data; and Feeding the load data to drive an actuator for a high fidelity random vibration simulation test.

    摘要翻译： 一种产生高保真模拟服务负载的简单且经济有效的方法。 然而，本发明提供了一种简单但理论上可行的方法来进行加速模拟测试，同时为测试获得合理的加速率。 通过开发服务负载历史数据库; 组合多个时间序列模型; 调整每个时间序列模型的变化创建加速服务负载模型; 再生随机振动载荷数据; 并加载负载数据以驱动执行器进行高保真随机振动模拟测试。

    Aminobenzoic acid derivatives having anti-tumorigenic activity, methods of making and using the same
    10.
    发明授权
    Aminobenzoic acid derivatives having anti-tumorigenic activity, methods of making and using the same 失效
    具有抗致瘤活性的氨基苯甲酸衍生物，制备和使用它们的方法

    公开(公告)号：US06590123B2

    公开(公告)日：2003-07-08

    申请号：US09941493

    申请日：2001-08-29

    申请人： George J Bekesi ,  Jian-Dong Jiang ,  Imre Weisz ,  John Roboz ,  James F Holland

    发明人： George J Bekesi ,  Jian-Dong Jiang ,  Imre Weisz ,  John Roboz ,  James F Holland

    IPC分类号： C07C23728

    CPC分类号： C07C275/54

    摘要： The present invention provides for haloacetoamido, benzoic acid derivatives having anti-tumorigenic activity. Examples of the haloacetoamido, benzoic acid derivatives include 3-chloroacetoamido, benzoylurea, 3-bromoacetoamido, benzoylurea, 3-iodoacetoamido, benzoylurea, ethyl-3-chloroacetoamido, benzoate, ethyl-3-bromoacetoamido, benzoate and ethyl-3-iodoacetoamido, benzoate. Intermediates for synthesizing the derivatives, along with methods of making and using the derivatives, are also provided.

    摘要翻译： 本发明提供具有抗致瘤作用的卤代乙酰氨基，苯甲酸衍生物。 卤代乙酰氨基，苯甲酸衍生物的实例包括3-氯乙酰氨基，苯甲酰脲，3-溴代乙酰氨基，苯甲酰脲，3-碘乙酰氨基，苯甲酰基脲，乙基-3-氯乙酰氨基，苯甲酸乙酯，3-溴代乙酰氨基乙酰胺，苯甲酸乙酯和乙基-3-碘代乙酰氨基， 。 还提供了用于合成衍生物的中间体以及制备和使用衍生物的方法。