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公开(公告)号：US10332279B2
公开(公告)日：2019-06-25
申请号：US15448591
申请日：2017-03-03
Applicant: Macau University of Science and Technology
Inventor： Zhanchuan Cai , Ting Lan
Abstract: A method constructs an image with improved peak signal-to-noise ratio (PSNR) from a scattered pixel set. The method generates an approximation function that is a linear combination of a plurality of Many-Knot (MK) spline basis functions, and constructs the image with improved PSNR by conducting a least squares treatment on the approximation function to minimize a residual of each pixel value in the scattered pixel set from the approximation function.
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公开(公告)号：US10296999B2
公开(公告)日：2019-05-21
申请号：US15431739
申请日：2017-02-13
Applicant: Macau University of Science and Technology
Inventor： Zhanchuan Cai
IPC: H04L9/00 , G06T1/00 , H04N19/467 , H04N1/32
Abstract: A method embeds a watermark image into a host image with adaptive rectangular partition and Lower Upper (LU) decomposition such that a watermarked image is generated with improved computational complexity. The method divides a host image into an Red (R) component, a Green (G) component, and a Blue (B) component, and divides each component of the R, G, and B components into a plurality of M×M size blocks, and partitions each of the plurality of M×M size blocks into a plurality of non-overlapping blocks with adaptive rectangular partition. The method selects a plurality of embedding blocks from the plurality of M×M size blocks for each component of the R, G, and B components of the host image to embed watermark information such that the watermarked image is generated.
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公开(公告)号：US10278955B1
公开(公告)日：2019-05-07
申请号：US15839875
申请日：2017-12-13
Applicant: Macau University of Science and Technology
Inventor： Xiao Jun Yao , Lai Han Elaine Leung , Liang Liu , Qian Qian Wang , Jia Hui Xu , Ying Li
IPC: A61K31/4045 , A61P35/00 , G01N33/574 , A61K45/06
Abstract: One embodiment is a method of treating cancer. The method includes administering a therapeutically effective amount of a compound to a patient. The compound is represented by Formula I:
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公开(公告)号：US10260114B2
公开(公告)日：2019-04-16
申请号：US15598434
申请日：2017-05-18
Inventor： Jin-Xiang Chen , Bin Sun , Bao-Ping Xie , Zhi-Hong Jiang , Li-Ping Bai
IPC: C07D213/50 , C12Q1/70 , C12Q1/6818 , C08G79/00
Abstract: The present invention relates in a first aspect to a method of preparing a crystalline lanthanum-carboxylate coordination polymer and the crystalline lanthanum-carboxylate coordination polymer obtained or obtainable by the method. In another aspect of the present invention, also provides a method of detecting a target nucleic acid sequence in a sample.
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公开(公告)号：US20190060273A1
公开(公告)日：2019-02-28
申请号：US15682564
申请日：2017-08-22
Applicant: Macau University of Science and Technology
IPC: A61K31/357 , A61K31/352 , A61K9/00 , A61K9/20
Abstract: One example embodiment relates to a method of increasing bioavailability of silybin in a person. The method includes providing silybin and a flavonoid to the person, wherein the flavonoid is tangeretin or baicalein. Another example embodiment relates to a method of treating chronic liver disease in a person by administering silybin and a flavonoid to the person to treat the chronic liver disease.
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Patent Agency Ranking
56.发明申请公开(公告)号：US20190017116A1
公开(公告)日：2019-01-17
申请号：US15647414
申请日：2017-07-12
Applicant: Macau University of Science and Technology
Inventor： Liang Liu , Lai Han Leung , Ying Li , Xiao Jun Yao , Hu Dan Pan
Abstract: A method of identifying a gene associated with a disease or pathological condition of the disease includes: a) obtaining a first group of exome sequences from a first population suffering from the disease or pathological condition and a second group of exome sequences from a second population not having the disease or pathological condition; b) identifying one or more variants in the first group by comparing it with the second group, and optionally with a public database, to generate a first set of variant data; c) applying a variant quality score calibration tool with a truth sensitivity threshold to remove false-positive variants having a sensitivity lower than the threshold and background variants from the first set of variant data so as to obtain a second set of variant data; d) removing synonymous variants from the second set of variant data to obtain a third set of variant data; and e) identifying one or more deleterious variants from the third set of variant data using a gene burden analysis, optionally generating a fourth set of variant data.
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公开(公告)号：US20190008872A1
公开(公告)日：2019-01-10
申请号：US15644945
申请日：2017-07-10
Applicant: Macau University of Science and Technology
Inventor： Liang Liu , Kam Wai Wong , Yuen Kwan Law , Cong Ling Qiu
IPC: A61K31/56 , A61K31/519 , A61K31/573 , A61K31/165
Abstract: A method for treating a subject suffering from refractory rheumatoid arthritis includes the step of administering an effective amount of a quinonemethide triterpenoid or a pharmaceutically tolerable salt, solvate or anhydrate thereof to the subject. Also is a method for inducing autophagy in a synovial fibroblast, and a method of inducing calcium mobilization in a synovial fibroblast. Further a pharmaceutical composition includes an effective dose of a quinonemethide triterpenoid and an anti-arthritis compound. The quinonemethide triterpenoid is suitable to treat refractory rheumatoid arthritis (RA) in particular ABC-protein-dependent RA and apoptosis-deficient RA. The quinonemethide triterpenoid also possesses significant inhibitory effects on the growth of synovial fibroblasts, in particular modulating the calcium homeostasis in multidrug-resistant rheumatoid arthritis synovial fibroblasts.
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公开(公告)号：US20180253896A1
公开(公告)日：2018-09-06
申请号：US15448591
申请日：2017-03-03
Applicant: Macau University of Science and Technology
Inventor： Zhanchuan CAI , Ting LAN
IPC: G06T17/30
CPC classification number: G06T11/00 , G06F17/175
Abstract: A method constructs an image with improved peak signal-to-noise ratio (PSNR) from a scattered pixel set. The method generates an approximation function that is a linear combination of a plurality of Many-Knot (MK) spline basis functions, and constructs the image with improved PSNR by conducting a least squares treatment on the approximation function to minimize a residual of each pixel value in the scattered pixel set from the approximation function.
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59.发明申请公开(公告)号：US20180227167A1
公开(公告)日：2018-08-09
申请号：US15427171
申请日：2017-02-08
Applicant: Macau University of Science and Technology
Inventor： Zhiwu Li , Syrine Ben Meskina , Mohamed Khalgui , Narjes Doggaz , Naiqi Wu
IPC: H04L12/24
CPC classification number: H04L41/0613 , H04L41/048 , H04L41/0609 , H04L41/0654 , H04L41/145
Abstract: A system for fault detection and recovery of a network includes a network simulation module arranged to receive component data regarding a plurality of components that form the network and simulate the network, a modelling module arranged to utilise the simulated network to model a number of faults in the network to determine the effect of the faults on the network, and a recovery module arranged to determine a solution to the fault on the network.
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公开(公告)号：US10037587B2
公开(公告)日：2018-07-31
申请号：US15360936
申请日：2016-11-23
Applicant: Macau University of Science and Technology
Inventor： Zhanchuan Cai
CPC classification number: G06T7/90 , G06T1/0028 , G06T1/005 , G06T2201/0061
Abstract: One example embodiment is a method to embed a watermark image into a host image such that a watermarked image is generated. The method divides a host image into an Red (R) component, a Green (G) component, and a Blue (B) component, and partitions each component of the R, G, and B components into non-overlapping blocks from which embedding blocks are selected to embed watermark information such that a watermarked image is generated.
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