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公开(公告)号：US10064745B2
公开(公告)日：2018-09-04
申请号：US14662171
申请日：2015-03-18
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Jason Van Sciver , Chad Abunassar
Abstract: A stent or scaffold has a tapered end or ends. The scaffold is made using an additive manufacturing technique such as stereolithography (SLA). The scaffold may take the shape of a frustum, or a scaffold having one or both of its ends flared. The scaffold has varying mechanical properties over its length, such as a varying ring stiffness, porosity or elasticity modulus. In one embodiment the strut and link widths change linearly from the distal to proximal ends.
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公开(公告)号：US10039656B2
公开(公告)日：2018-08-07
申请号：US13910998
申请日：2013-06-05
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Erik David Eli , Syed Hossainy , Mikael Trollsas , Michael H. Ngo , Stephen Pacetti , Michael Green , John Papp
Abstract: A scaffold is formed by several segments joined or connected to each other by only at least one coupling. The coupling decouples the segments in the axial direction over a finite distance of axial displacement. The scaffold when implanted in a peripheral vessel reduces loading on rings of a segment due to the decoupling of the segments in the axial direction over the finite distance.
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公开(公告)号：US09878169B2
公开(公告)日：2018-01-30
申请号：US14650818
申请日：2013-12-18
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , Syed Hossainy
Inventor： Syed Hossainy
CPC classification number: A61N1/3756 , A61F7/12 , A61F2007/126 , A61M39/0247 , A61M2039/0258 , A61M2039/0261 , A61N1/3627 , A61N1/3785
Abstract: Various medical implants and methods of using the implants are disclosed. In an embodiment, the implants include piezoelectric polymers for treating unwanted medical conditions of a patient. The medical implants may be delivered to an organ of the patient to treat conditions of those organs.
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公开(公告)号：US20160374840A9
公开(公告)日：2016-12-29
申请号：US14881073
申请日：2015-10-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the marker support structures.
Abstract translation: 公开了一种制造支架的方法。 支架包括最小卷曲直径，使得在最小卷曲直径处，标记支撑结构所在的一对支架环不与标记支撑结构接触。 本发明的支架的卷曲轮廓可以与同一支架的卷曲轮廓一样小，但没有标记支撑结构。
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公开(公告)号：US09289318B2
公开(公告)日：2016-03-22
申请号：US14656553
申请日：2015-03-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Dariush Davalian , Michael Huy Ngo , Hao-Ming Hsiao , Boris Anukhin , Syed Hossainy , David Gale
CPC classification number: A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/828 , A61F2210/0004 , A61F2230/0054 , A61F2250/0036 , A61L31/06 , A61L31/10 , A61L31/148 , C08L67/04
Abstract: A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements.
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Patent Agency Ranking
公开(公告)号：US09198785B2
公开(公告)日：2015-12-01
申请号：US14097172
申请日：2013-12-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the marker support structures.
Abstract translation: 公开了一种制造支架的方法。 支架包括最小卷曲直径，使得在最小卷曲直径处，标记支撑结构所在的一对支架环不与标记支撑结构接触。 本发明的支架的卷曲轮廓可以与同一支架的卷曲轮廓一样小，但没有标记支撑结构。
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57.发明申请Methods and Devices for Treating a Bodily Lumen with In Situ Generated Structural Support 审中-公开用原位生成的结构支持治疗身体的方法和装置公开(公告)号：US20150305892A1
公开(公告)日：2015-10-29
申请号：US14262516
申请日：2014-04-25
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Krishna Sudhir , John Stankus , Mikael Trollsas
CPC classification number: A61F2/50 , A61F2/82 , A61F2210/0004 , A61F2210/0085 , A61L27/18 , A61L27/50 , A61L27/58 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/148 , A61L2300/624 , A61L2400/06 , A61L2400/12 , C08L67/04 , C08L71/02
Abstract: A bodily lumen, such as a blood vessel, can be treated by forming a structural support in situ within the bodily lumen. This can be done by ejecting a formulation that includes a polymer that solidifies over a period of time, such as due to DMSO exchange or photocrosslinking. This can also be done by cooling a formulation until it freezes in situ. The structural support can also be made from a plaque which is already present in the bodily lumen. The plaque can be compressed by a balloon catheter and cooled so that it hardens and thereby forms the structural support. The bodily lumen can also be treated using a preformed structural support made of ice, for example frozen isotonic saline, or a fast degrading polymer, such as PEG. The preformed support is created outside of the bodily lumen, and then transported on a catheter to the treatment zone.
Abstract translation: 可以通过在体腔内原位形成结构支架来治疗诸如血管的体腔。 这可以通过喷射包括在一段时间内固化的聚合物的制剂来实现，例如由于DMSO交换或光致交联。 这也可以通过冷却制剂直到其原位冻结来完成。 结构支撑物也可以由已经存在于体腔中的斑块制成。 斑块可以通过气囊导管压缩并冷却，使得其硬化并由此形成结构支撑。 还可以使用由冰制成的预制结构支撑物例如冷冻等渗盐水或快速降解聚合物例如PEG来处理身体腔。 预先形成的支撑体在体腔外部产生，然后在导管上运送到治疗区域。
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公开(公告)号：US08865148B2
公开(公告)日：2014-10-21
申请号：US14149533
申请日：2014-01-07
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar W. Kleiner , Syed Hossainy , Stephen Pacetti , Jessica DesNoyer
IPC: A61K31/74 , C08L77/12 , A61K9/08 , A61K31/337 , A61K47/48 , A61K31/4745 , A61K47/34 , A61K9/10 , A61K9/00
CPC classification number: A61K47/48207 , A61K9/0024 , A61K9/08 , A61K9/10 , A61K31/337 , A61K31/4745 , A61K31/727 , A61K47/34 , A61K47/593 , A61K47/595 , A61K47/60 , C08L77/12 , C08L2205/02 , C08L2666/20
Abstract: A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the therapeutic agent delivery system by delivering the therapeutic agent delivery system formed of a PEA polymer, a therapeutic agent, and a water miscible solvent to a physiological environment and separating the phase of the therapeutic agent delivery system to form a membrane from the polymer to contain the therapeutic agent within the physiological environment is also described. Additionally disclosed is a kit including a syringe and a therapeutic agent delivery system within the syringe.
Abstract translation: 本文描述了由特定类型的聚（酯酰胺）（PEA），治疗剂和水混溶性溶剂形成的治疗剂递送系统。 通过将由PEA聚合物，治疗剂和水混溶性溶剂形成的治疗剂递送系统递送到生理环境来递送治疗剂递送系统的方法，并分离治疗剂递送系统的相以形成膜 还描述了在生理环境中含有治疗剂的聚合物。 另外公开了一种试剂盒，其包括注射器内的注射器和治疗剂递送系统。
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公开(公告)号：US20140277372A1
公开(公告)日：2014-09-18
申请号：US13840257
申请日：2013-03-15
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Michael Huy Ngo , Samit Mustafa , Syed Hossainy , Mikael Trollsas
IPC: A61F2/82
CPC classification number: A61F2/82 , A61F2/915 , A61F2002/91575 , B29C49/08 , B29C55/26 , B29C2793/0009 , B29L2031/753 , B29L2031/7542 , Y10T29/49863
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a morphology resulting from a biaxially expanded tube arranged to provide a more balanced, or less anisotropic axial and radial mechanical properties. The scaffold has improved mechanical properties suited for use as a balloon expandable scaffold implanted in a peripheral vessel of the body.
Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架具有由双轴向膨胀的管形成的形状，其布置成提供更平衡或更不均匀的轴向和径向机械性能。 支架具有改善的机械性能，适合用作植入身体外周血管中的球囊扩张型支架。
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公开(公告)号：US20140212355A1
公开(公告)日：2014-07-31
申请号：US13752281
申请日：2013-01-28
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Mikael TROLLSAS , Syed Hossainy , John Stankus , Paul Consigny
IPC: A61K9/00
CPC classification number: A61L31/145 , A61L31/06 , A61L31/16 , A61L2300/416 , A61L2400/12 , A61L2430/36 , C08L67/04 , C08L71/02
Abstract: It is provided herein methods, devices, and compositions for trans-arterial local delivery of therapeutic agent for the treatment of liver cancers.
Abstract translation: 本文提供用于治疗肝癌的治疗剂的跨动脉局部递送的方法，装置和组合物。
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