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    Preshaped localization catheter, system, and method for graphically reconstructing pulmonary vein ostia
    51.
    发明授权
    Preshaped localization catheter, system, and method for graphically reconstructing pulmonary vein ostia 有权
    定位导管，系统，图像重建肺静脉口腔的方法

    公开(公告)号：US08535303B2

    公开(公告)日：2013-09-17

    申请号：US11429051

    申请日：2006-05-05

    申请人： Boaz Avitall ,  Josef V. Koblish

    发明人： Boaz Avitall ,  Josef V. Koblish

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1492 ,  A61B6/06 ,  A61B2017/003 ,  A61B2018/00375 ,  A61B2034/2051 ,  A61M25/0144 ,  A61M25/0147 ,  A61M25/0152 ,  A61M2025/0161

    摘要： Catheters, systems, and methods are provided for performing medical procedures, such as tissue ablation, adjacent the ostia of anatomical vessels, such as pulmonary veins. The catheter comprises an elongated flexible catheter body, which includes a proximal shaft portion and a distal shaft portion, and a tracking element carried by the distal shaft portion. The proximal section is pre-shaped to form a curve having an apex sized to be inserted into the vessel ostium, and a distal section configured to contact the adjacent tissue when the curve apex is inserted within the vessel ostium. The method may comprise inserting the curve apex into the vessel ostium to place the distal section in contact with a first tissue site adjacent the vessel ostium, and determining a location of the tracking element(s) within a coordinate system while the distal section is in contact with the first tissue site.

    摘要翻译： 提供导管，系统和方法用于执行诸如组织消融的医学程序，邻近解剖血管的口，例如肺静脉。 导管包括细长的柔性导管主体，其包括近侧轴部分和远侧轴部分，以及由远端轴部分承载的跟踪元件。 近端部分被预成形以形成具有顶点尺寸设置成插入容器口中的曲线，以及当曲线顶点插入血管口内时构造成接触相邻组织的远侧部分。 该方法可以包括将曲线顶点插入血管口中以将远侧部分与邻近血管口的第一组织部位接触，并且在远侧部位处于坐标系中时确定跟踪元件在坐标系内的位置 与第一个组织部位接触。

    Cooled ablation catheter
    52.
    发明授权
    Cooled ablation catheter 有权
    冷却消融导管

    公开(公告)号：US07938828B2

    公开(公告)日：2011-05-10

    申请号：US10402891

    申请日：2003-03-28

    申请人： Josef V. Koblish

    发明人： Josef V. Koblish

    IPC分类号： A61B18/18

    CPC分类号： A61B18/1492 ,  A61B2017/003 ,  A61B2018/00011 ,  A61B2018/00791

    摘要： Steerable catheter that has fluid transfer capability is provided. The catheter includes an elongate flexible shaft having a proximal end and a distal end, an operative element carried at the distal end of the shaft, and a medium conveying conduit carried within the elongate shaft, the conduit having a distal end that is affixed relative to the distal end of the elongate shaft, and a proximal end that is configured to move relative to the proximal end of the shaft. In this manner, the proximal end of the medium conveying conduit is allowed to slide relative to the proximal end of the shaft as the distal end of the shaft changes shape, thereby preventing kinking of the conduit.

    摘要翻译： 提供了具有流体传递能力的导向导管。 导管包括具有近端和远端的细长柔性轴，在轴的远端承载的操作元件和在细长轴内承载的介质输送导管，该导管具有相对于 细长轴的远端以及被配置为相对于轴的近端移动的近端。 以这种方式，当轴的远端改变形状时，允许介质输送管道的近端相对于轴的近端滑动，从而防止管道的扭结。

    STEERABLE CATHETER HAVING INTERMEDIATE STIFFNESS TRANSITION ZONE
    53.
    发明申请
    STEERABLE CATHETER HAVING INTERMEDIATE STIFFNESS TRANSITION ZONE 有权
    具有中间强度转换区的可转向导管

    公开(公告)号：US20100217184A1

    公开(公告)日：2010-08-26

    申请号：US12708114

    申请日：2010-02-18

    申请人： Josef V. Koblish ,  Mark Forrest ,  Zaya Tun

    发明人： Josef V. Koblish ,  Mark Forrest ,  Zaya Tun

    IPC分类号： A61M25/08 ,  A61M25/092

    CPC分类号： A61M25/0141 ,  A61M25/0144 ,  A61M25/0147

    摘要： A flexible, steerable intravascular catheter includes an elongate flexible shaft having a heterogeneous or multi-zone stiffness profile or structure. A first or distal portion of the catheter shaft may have a substantially constant or distinct stiffness or flexibility, a second, intermediate or transition section is proximal relative to, and less flexible than, the first section, and a third section is proximal relative to, and also less more flexible than, the first section. The third section also includes a substantially constant or distinct stiffness or flexibility. The flexibility or stiffness of the second section varies along its length, e.g., in a substantially linear, step-like or ramp-like manner to provide a smooth or gradual transition between the stiffness of the first or distal section and the flexibility or stiffness of the third or proximal section.

    摘要翻译： 柔韧的，可操纵的血管内导管包括具有异质或多区域刚度分布或结构的细长柔性轴。 导管轴的第一或远端部分可以具有基本上恒定或不同的刚度或柔性，第二中间或过渡部分相对于第一部分近端并且比第一部分更柔性，并且第三部分相对于第二部分近端， 并且也比第一部分更不灵活。 第三部分还包括基本上恒定或不同的刚度或柔性。 第二部分的柔韧性或刚度沿其长度变化，例如以基本线性的阶梯状或斜坡状方式变化，以提供第一或远端部分的刚度之间的平滑或逐渐过渡，以及柔性或刚度 第三或近端部分。

    MEDICAL PROBES FOR CREATING AND DIAGNOSING CIRCUMFERENTIAL LESIONS WITHIN OR AROUND THE OSTIUM OF A VESSEL
    56.
    发明申请
    MEDICAL PROBES FOR CREATING AND DIAGNOSING CIRCUMFERENTIAL LESIONS WITHIN OR AROUND THE OSTIUM OF A VESSEL 有权
    用于创建和诊断血管内皮细胞或其周围的周围淋巴结的医学探针

    公开(公告)号：US20090018534A1

    公开(公告)日：2009-01-15

    申请号：US12209124

    申请日：2008-09-11

    申请人： Miriam H. Taimisto ,  Josef V. Koblish

    发明人： Miriam H. Taimisto ,  Josef V. Koblish

    IPC分类号： A61B18/18

    CPC分类号： A61B18/1492 ,  A61B2017/00044 ,  A61B2017/00243 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00375 ,  A61B2018/00839 ,  A61B2018/1435

    摘要： The present inventions provide assemblies, probes, and methods for creating circumferential lesions in tissue, e.g., the tissue within or around the ostium of a vessel. An ablation probe with an ablative structure can be placed in contact within or around the ostium of the vessel. A diagnostic probe can be introduced through a lumen within the ablation probe and inserted into the vessel. The energy can be provided to the ablative structure to create a circumferential lesion within or around the ostium of the vessel, and the diagnostic structure can be used to diagnose the tissue to determine whether the circumferential lesion can be properly created.

    摘要翻译： 本发明提供用于在组织中产生周向损伤的组件，探针和方法，例如在血管的口内或周围的组织。 具有烧蚀结构的消融探针可以在容器的口中或周围接触放置。 诊断探针可以通过消融探针中的内腔引入并插入血管。 可以将能量提供给烧蚀结构以在容器的口内或周围形成周缘损伤，并且诊断结构可用于诊断组织以确定是否可以适当地产生周缘损伤。