公开(公告)号：US11331022B2

公开(公告)日：2022-05-17

申请号：US17349755

申请日：2021-06-16

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: G08B21/20 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20210393877A1

公开(公告)日：2021-12-23

申请号：US17464547

申请日：2021-09-01

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: A61M5/172 ,  A61M15/00 ,  A61M35/00 ,  A61M5/20 ,  G16H20/17 ,  A61M5/142 ,  A61M11/00 ,  A61B5/145 ,  G16H40/63

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20210353185A1

公开(公告)日：2021-11-18

申请号：US17444148

申请日：2021-07-30

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Paul V. Neale ,  Sebastian Böhm ,  Matthew D. Wightlin ,  Jack Pryor ,  Jason Mitchell ,  Jeff Jackson ,  Kaushik Patel ,  Antonio C. Llevares

IPC: A61B5/1473 ,  A61B5/1486 ,  B05C3/12 ,  B05C3/02 ,  A61B5/145 ,  B05C3/10

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

公开(公告)号：US20210330219A1

公开(公告)日：2021-10-28

申请号：US17368541

申请日：2021-07-06

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US11051731B2

公开(公告)日：2021-07-06

申请号：US16911172

申请日：2020-06-24

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66 ,  A61B5/1486

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US10729364B2

公开(公告)日：2020-08-04

申请号：US16407055

申请日：2019-05-08

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66 ,  A61B5/1486

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US20190339223A1

公开(公告)日：2019-11-07

申请号：US16402116

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/327

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20190339222A1

公开(公告)日：2019-11-07

申请号：US16402101

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/327

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20190307371A1

公开(公告)日：2019-10-10

申请号：US16452364

申请日：2019-06-25

Applicant: DexCom, Inc.

Inventor： Robert Boock ,  Jeff Jackson ,  Huashi Zhang ,  Jason Mitchell

IPC: A61B5/1473 ,  A61B5/145 ,  A61B5/1486 ,  B05C3/10

Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice. For example, a provided elongated conductive body 510 is advanced through a pre-coating treatment station 520, through a coating station 530, through a thickness control station 540, through a drying or curing station 550, through a thickness measurement station 560, and through a post-coating treatment station 570.

公开(公告)号：US20190261904A1

公开(公告)日：2019-08-29

申请号：US16407055

申请日：2019-05-08

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.