公开(公告)号：US20180228606A1

公开(公告)日：2018-08-16

申请号：US15953991

申请日：2018-04-16

Applicant: Edwards Lifesciences Corporation

Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439 ,  A61F2002/9517 ,  A61F2002/9522 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/001 ,  A61F2230/0054 ,  A61F2230/0076 ,  A61F2250/0039

Abstract: Embodiments of the present disclosure provide methods of loading a prosthetic heart valve within a delivery apparatus such that it can be used for delivery of the prosthetic heart valve to a native valve site via the human vasculature. The methods can include attaching the prosthetic heart valve to a valve-retaining mechanism at a distal end of the catheter and causing a torque shaft of the delivery apparatus to rotate relative to the catheter, wherein the torque shaft extends within the catheter and is coupled to the valve delivery sheath. Rotation of the torque shaft relative to the catheter can cause relative longitudinal movement between the valve sheath and the prosthetic heart valve such that the prosthetic heart valve is covered by the valve sheath.

公开(公告)号：US20180200055A1

公开(公告)日：2018-07-19

申请号：US15918240

申请日：2018-03-12

Applicant: Edwards Lifesciences Corporation

Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439 ,  A61F2002/9517 ,  A61F2002/9522 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/001 ,  A61F2230/0054 ,  A61F2230/0076 ,  A61F2250/0039

Abstract: Embodiments of the present disclosure provide a prosthetic heart valve usable with a heart valve delivery apparatus for delivery of the prosthetic heart valve to a native valve site via the human vasculature. In one embodiment, a self-expanding valve comprises an expandable stent that is shaped to maintain the valve in the aortic annulus against axial without anchors or retaining devices that engage the surrounding tissue. The prosthetic heart valve can have a curved shape that tapers inwardly from the inflow end to a reduced diameter section, increases in diameter from the reduced diameter section to an intermediate section, and then tapers from the intermediate section to the outflow end

公开(公告)号：US20170165055A1

公开(公告)日：2017-06-15

申请号：US15443289

申请日：2017-02-27

Applicant: Edwards Lifesciences Corporation

Inventor： David L. Hauser ,  Jan Otto Solem ,  David Alon

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2445 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016

Abstract: A prosthetic device for treating a mitral valve includes a prosthetic insert member insertable between leaflets of mitral valve. The insert member has an elongated cross-sectional profile for conforming to gap between leaflets of a mitral valve. The device also includes an anchoring member for attachment to heart tissue for maintaining the insert member in the mitral valve. The insert member includes a valve that permits one-way blood flow therethrough. An anchoring member secures the prosthetic insert member to a heart wall.

公开(公告)号：US09364325B2

公开(公告)日：2016-06-14

申请号：US14182169

申请日：2014-02-17

Applicant: Edwards Lifesciences Corporation

Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439 ,  A61F2002/9517 ,  A61F2002/9522 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0076 ,  A61F2250/0039

Abstract: A method for delivering a self-expanding prosthetic heart valve comprises positioning the prosthetic heart valve in an annulus of a native heart valve while mounted in a radially compressed state in a delivery cylinder, the delivery cylinder coupled to a distal end portion of the torque shaft, and rotating a torque shaft coupled to the delivery cylinder. Rotating the torque shaft retracts the delivery cylinder, thereby exposing the prosthetic heart valve, allowing the prosthetic heart valve to self-expand in the native valve annulus. In some embodiments, the torque shaft is rotated by a motor disposed in a handle at a proximal end of the delivery device.

Abstract translation: 用于递送自膨胀假体心脏瓣膜的方法包括将假体心脏瓣膜定位在天然心脏瓣膜的环形空间中，同时以放射状压缩状态安装在输送圆筒中，输送圆筒联接到扭矩轴的远端部分 并且旋转联接到输送圆筒的扭矩轴。 旋转扭矩轴缩回输送缸，从而暴露假体心脏瓣膜，允许假体心脏瓣膜在天然瓣膜环中自扩张。 在一些实施例中，转矩轴由设置在输送装置的近端处的手柄中的电动机旋转。

公开(公告)号：US20140163670A1

公开(公告)日：2014-06-12

申请号：US14182169

申请日：2014-02-17

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439 ,  A61F2002/9517 ,  A61F2002/9522 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0076 ,  A61F2250/0039

Abstract: A method for delivering a self-expanding prosthetic heart valve comprises positioning the prosthetic heart valve in an annulus of a native heart valve while mounted in a radially compressed state in a delivery cylinder, the delivery cylinder coupled to a distal end portion of the torque shaft, and rotating a torque shaft coupled to the delivery cylinder. Rotating the torque shaft retracts the delivery cylinder, thereby exposing the prosthetic heart valve, allowing the prosthetic heart valve to self-expand in the native valve annulus. In some embodiments, the torque shaft is rotated by a motor disposed in a handle at a proximal end of the delivery device.

Abstract translation: 用于递送自扩张假体心脏瓣膜的方法包括将假体心脏瓣膜定位在天然心脏瓣膜的环中，同时以放射状压缩状态安装在输送圆筒中，输送圆筒联接到扭矩轴的远端部分 并且旋转联接到输送缸的扭矩轴。 旋转扭矩轴缩回输送缸，从而暴露假体心脏瓣膜，允许假体心脏瓣膜在天然瓣膜环中自扩张。 在一些实施例中，转矩轴由位于输送装置的近端处的手柄中的电动机旋转。