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公开(公告)号：US20090101838A1
公开(公告)日：2009-04-23
申请号：US11975702
申请日：2007-10-18
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： A61K41/0057 , A61K41/0019 , A61K41/0042
摘要： A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.
摘要翻译： 一种方法，组成和系统响应电离辐射来调节生物活性。 在一些方法中，电离辐射是产生引发生物活性反应的发光反应的X射线或极紫外辐射。
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52.发明申请X-ray fluorescence visualizing, imaging, or information providing of chemicals, compounds, or biological materials 有权化学，化合物或生物材料的X射线荧光可视化，成像或信息提供公开(公告)号：US20090086901A1
公开(公告)日：2009-04-02
申请号：US11906151
申请日：2007-09-28
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： G01N23/223 , G01N23/225
CPC分类号： G01N23/223 , A61B5/415 , A61B5/418 , A61B5/489 , A61B6/12 , A61B6/14 , A61B6/4021 , A61B6/4291 , A61B6/482 , A61B6/485 , A61B6/50 , A61B6/501 , A61B6/502 , A61B6/503 , A61B6/504 , A61B6/505 , A61B6/506 , A61B6/507 , A61B6/508 , A61B2503/40 , G01N2223/076
摘要： One aspect can relate to detecting a presence of an at least one chemical, compound, or biological material contained in an at least some matter of an at least a portion of an at least one individual based at least partially on addition of an at least one chemical identifying additive to the at least some matter of the at least the portion of the at least one individual based at least partially on a generation of an at least one induced X-ray fluorescing photon within the at least one chemical identifying additive responsive to a single input energy event in which an at least some input energy is being applied proximal to the at least one chemical, compound, or biological material contained in the at least some matter of the at least the portion of the at least one individual.
摘要翻译： 一个方面可以涉及至少部分地基于添加至少一个个体的至少一个个体的至少一部分的至少一些物质中的至少一种化学，化合物或生物材料的存在来检测 至少部分地至少部分地基于在所述至少一种化学鉴定添加剂中产生至少一种诱导的X射线荧光光子的化学鉴定添加剂至少部分至少一部分物质的化学鉴定添加剂，其响应于 单输入能量事件，其中至少一些输入能量被施加在至少一个化学，化合物或生物材料的近端，该至少一种化学，化合物或生物材料包含在至少一个个体的至少一部分的该至少一些物质中。
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53.发明申请Tool based X-ray fluorescence visualizing, imaging, or information providing 失效基于工具的X射线荧光可视化，成像或信息提供公开(公告)号：US20090086896A1
公开(公告)日：2009-04-02
申请号：US11906169
申请日：2007-09-28
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： G01N23/223
CPC分类号： G01N23/223 , G01N2223/076
摘要： Certain embodiments of one aspect relates to inducing at least one induced X-ray fluorescing photon within an at least some matter of an at least a portion of an at least one individual responsive to an at least some input energy being applied to the at least some matter of the least the portion of the at least one individual. The aspect can include X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the least the portion of the at least one individual at least partially in response to the inducing at least one induced X-ray fluorescing photon within the at least some matter of the least the portion of the at least one individual. Certain embodiments of the aspect can include providing a substantial real time tool-based operation to the at least some matter of the least the portion of the at least one individual at least partially relying on the X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the least the portion of the at least one individual.
摘要翻译： 一个方面的某些实施方案涉及在至少一些输入能量的至少一些输入能量的至少一个的至少一部分内的至少一些物质内诱导至少一个诱导的X射线荧光光子，所述至少一些输入能量被施加到所述至少一些 至少一个人的至少一部分的事物。 所述方面可以包括至少部分响应于诱导至少一个诱导的X射线荧光光子的至少一个个体的至少一部分内的至少一些物质内的X射线荧光可视化，成像或信息提供 所述至少一个个体的至少一部分的至少一部分。 该方面的某些实施例可以包括至少部分地依赖于X射线荧光可视化，成像或提供信息的至少一个个体的至少一部分的至少一些物质提供基本实时的基于工具的操作 在至少一个个体的至少一部分内的至少一些事物内。
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54.发明申请Proximity-based X-ray fluorescence visualizer, imager, or information provider 有权基于接近度的X射线荧光可视化仪，成像仪或信息提供者公开(公告)号：US20090086892A1
公开(公告)日：2009-04-02
申请号：US11906135
申请日：2007-09-28
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Robert W. Lord , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： G01N23/223 , G01N23/225
CPC分类号： A61B6/503 , A61B5/415 , A61B5/418 , A61B5/489 , A61B6/12 , A61B6/14 , A61B6/4021 , A61B6/4291 , A61B6/482 , A61B6/485 , A61B6/50 , A61B6/501 , A61B6/502 , A61B6/504 , A61B6/505 , A61B6/506 , A61B6/507 , A61B6/508 , A61B2503/40 , G01N23/223 , G01N2223/076
摘要： One aspect relates to detecting at least one induced X-ray fluorescing photon fluoresced from substantially within an at least some matter of an at least a portion of an at least one individual at least partially as a result of receiving at least one induced X-ray fluorescing photon generated at least partially within at least one X-ray fluorescence event within the at least some matter of the at least the portion of the at least one individual which has been generated responsive to an at least some input energy resulting from a single input energy event, wherein the at least one induced X-ray fluorescing photon that has passed through the at least some matter of the at least the portion of the at least one individual is at a level to substantially limit interference between the at least one induced X-ray fluorescing photon with an at least one other induced X-ray fluorescing photon that travel for distances greater than a prescribed limit through the at least some matter of the at least the portion of the at least one individual, wherein the at least one other induced X-ray fluorescing photon attenuates by a prescribed percentage after passing through the prescribed distance through the at least some matter of the at least the portion of the at least one individual.
摘要翻译： 一个方面涉及至少部分地检测至少一个感兴趣的X射线荧光光子，其基本上在至少一个个体的至少一部分的至少一些物质内发射，作为接收至少一个诱导X射线 至少部分地在至少一个X射线荧光事件中产生荧光光子，所述至少一个X射线荧光事件在所述至少一个个体的至少一部分中的至少一些物质中响应于由单个输入产生的至少一些输入能量而产生 能量事件，其中已经通过所述至少一个个体的至少一部分的至少一些物质的所述至少一个感兴趣的X射线荧光光子处于基本上限制所述至少一个诱导X 具有至少一个其它诱导的X射线荧光光子的荧光光子，其行进距离大于规定的极限，通过至少一些事件 所述至少一个个体的部分，其中所述至少一个其它诱导的X射线荧光光子在经过所述规定距离之后通过所述至少一个的所述至少一部分的所述至少一些物质衰减预定百分比 个人。
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公开(公告)号：US20090024140A1
公开(公告)日：2009-01-22
申请号：US11880432
申请日：2007-07-20
申请人： Paul G. Allen , Edward Boyden , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Paul G. Allen , Edward Boyden , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61B19/00
CPC分类号： A61B90/06 , A61B34/20 , A61B34/76 , A61B2090/033 , A61B2090/062 , A61B2090/064 , A61B2090/08021
摘要： The invention pertains to a surgical system. In an embodiment, the system comprises one or more sensors operably responsive to physical boundary limitations of an operating field. Furthermore, the one or more sensors provide information regarding the physical boundary limitations of the operating field. In another embodiment, the system comprises a surgical instrument that is configured to respond to the information by either activation or inactivation. In another aspect the invention includes generating an anatomical image or anatomic positional reference data. Additionally, the method includes creating haptic feedback signals based at least partly on the anatomical image or anatomic positional reference data, and determining a position or orientation of a surgical instrument. Furthermore the method includes activating or inactivating the surgical instrument based at least partly on the haptic feedback signals.
摘要翻译： 本发明涉及一种手术系统。 在一个实施例中，系统包括可操作地响应于操作场的物理边界限制的一个或多个传感器。 此外，一个或多个传感器提供关于操作区域的物理边界限制的信息。 在另一个实施例中，系统包括被配置为通过激活或失活响应信息的外科器械。 在另一方面，本发明包括生成解剖图像或解剖学位置参考数据。 另外，该方法包括至少部分地基于解剖图像或解剖学位置参考数据创建触觉反馈信号，以及确定外科器械的位置或取向。 此外，该方法包括至少部分地基于触觉反馈信号来激活或失活外科器械。
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公开(公告)号：US20130170022A1
公开(公告)日：2013-07-04
申请号：US13374520
申请日：2011-12-29
申请人： Kenneth G. Caldeira , Peter L. Hagelstein , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Nathan P. Myhrvold , John Brian Pendry , David Schurig , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR.
发明人： Kenneth G. Caldeira , Peter L. Hagelstein , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Nathan P. Myhrvold , John Brian Pendry , David Schurig , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR.
CPC分类号： G02B27/0093 , A61B3/1015 , A61B3/113 , A61B3/14 , A61B3/152 , G02B7/28 , G02B7/365 , G02B21/24 , G02B23/12 , G02B26/06 , G02B27/0025 , G02B27/022 , G02C2202/22 , G06K9/00604
摘要： Exemplary methods, systems and components enable an enhanced direct-viewing optical device to make customized adjustments that accommodate various optical aberrations of a current user. In some instances a real-time adjustment of the transformable optical elements is based on known corrective optical parameters associated with a current user. In some implementations a control module may process currently updated wavefront measurements as a basis for determining appropriate real-time adjustment of the transformable optical elements to produce a specified change in optical wavefront at an exit pupil of the direct-viewing device. Possible transformable optical elements may have refractive and/or reflective and/or diffractive and/or transmissive characteristics that are adjusted based on current performance viewing factors for a given field of view of the direct-viewing device. Some embodiments enable dynamic repositioning and/or transformation of corrective optical elements based on a detected shift of a tracked gaze direction of a current user of the direct-viewing device.
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公开(公告)号：US20130169928A1
公开(公告)日：2013-07-04
申请号：US13385688
申请日：2012-02-29
申请人： Kenneth G. Caldeira , Peter L. Hagelstein , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Nathan P. Myhrvold , John Brian Pendry , David Schurig , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR.
发明人： Kenneth G. Caldeira , Peter L. Hagelstein , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Nathan P. Myhrvold , John Brian Pendry , David Schurig , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR.
CPC分类号： G02B25/001 , A61B3/0075 , A61B3/1015 , G02B26/06 , G02B27/005 , G02C2202/22
摘要： Exemplary methods, systems and components enable an enhanced direct-viewing optical device to include customized adjustments that accommodate various optical aberrations of a current user. A real-time adjustment of transformable optical elements is sometimes based on predetermined corrective optical parameters associated with a current user. Customized optical elements are incorporated with the direct-viewing optical device to produce a specified change in optical wavefront at an exit pupil. Possible transformable or replacement optical elements may have refractive and/or reflective and/or diffractive and/or transmissive characteristics that are selected based on current performance viewing factors for a given field of view of the direct-viewing device. Some embodiments enable dynamic repositioning and/or transformation of corrective optical elements responsive to a detected shift of a tracked gaze direction of a current user. Replacement corrective optical elements may be fabricated for current usage or retained in inventory for possible future usage in the direct-viewing device.
摘要翻译： 示例性方法，系统和组件使得增强的直视光学装置能够包括适应当前用户的各种光学像差的定制调整。 可变形光学元件的实时调整有时基于与当前用户相关联的预定校正光学参数。 定制的光学元件与直视光学装置并入，以在出射光瞳处产生光学波前的特定变化。 可能的可变形或替换的光学元件可以具有基于直观观察装置的给定视场的当前性能观察因子而选择的折射和/或反射和/或衍射和/或透射特性。 一些实施例使得能够响应于检测到的当前用户的跟踪注视方向的移位而对校正光学元件进行动态重新定位和/或变换。 替代校正光学元件可以被制造用于当前使用或保留在库存中以用于将来在直接观看设备中的使用。
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公开(公告)号：US20110274586A1
公开(公告)日：2011-11-10
申请号：US13134250
申请日：2011-06-01
申请人： Roderick A. Hyde , Edward K.Y. Jung , William Henry Mangione-Smith , Nathan P. Myhrvold , John Brian Pendry , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR.
发明人： Roderick A. Hyde , Edward K.Y. Jung , William Henry Mangione-Smith , Nathan P. Myhrvold , John Brian Pendry , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR.
摘要： A plasmon filter may include an element supportive of plasmon energy and having a plurality of openings through which a material may pass. A system includes a fluid filter supportive of evanescent energy, an evanescent field generator, a sensor, and/or other components. A corresponding method may include generating plasmons on the filter and exposing a material to the plasmon energy.
摘要翻译： 等离子体激元滤波器可以包括支持等离子体激元能量的元件，并且具有多个开口，材料可通过该开口通过。 系统包括支持ev逝能量的流体过滤器，ev逝场发生器，传感器和/或其他部件。 相应的方法可以包括在过滤器上产生等离子体激元并将材料暴露于等离子体激元能量。
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公开(公告)号：US20100104834A1
公开(公告)日：2010-04-29
申请号：US12378086
申请日：2009-02-09
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Alois A. Langer , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR. , Richard N. Zare
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Alois A. Langer , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR. , Richard N. Zare
IPC分类号： B32B7/00
CPC分类号： C08J9/40 , Y10T428/24802 , Y10T428/24917
摘要： Articles having porous or foam-like elements are provided. The design, fabrication and structures of the articles exploit properties of reactive composite materials (RCM) and their reaction products. In particular, fluids generated by reacting RCM are utilized to create or fill voids in the porous or foam-like elements.
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公开(公告)号：US20090145911A1
公开(公告)日：2009-06-11
申请号：US12008695
申请日：2008-01-10
申请人： Roderick A. Hyde , Edward K.Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , William H. Gates, III , Charles Whitmer , Lowell L. Wood, JR.
发明人： Roderick A. Hyde , Edward K.Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , William H. Gates, III , Charles Whitmer , Lowell L. Wood, JR.
IPC分类号： B65D81/38
CPC分类号： B65D81/18 , A01N1/0263 , A61J1/165 , A61J2200/42 , A61J2200/44 , A61J2200/72 , A61J2200/74 , A61J2200/76 , B65D81/3802 , B65D81/3811 , B65D81/3813 , B65D81/3823 , B65D81/3825 , B65D81/3834 , B65D81/3888 , B65D81/3897 , B65D2203/10
摘要： Systems include integrally sealed medicinal storage containers, including one or more segments of an ultra efficient insulation material, the one or more segments having one or more surface regions, the one or more segments principally defining at least one storage region, and one or more regions of substantially thermally sealed connections between at least one of the one or more surface regions of the one or more segments wherein the one or more regions of substantially thermally sealed connections and the one or more segments form an integrally thermally sealed medicinal storage region.
摘要翻译： 系统包括整体密封的药物储存容器，包括一个或多个超高效绝缘材料段，所述一个或多个区段具有一个或多个表面区域，所述一个或多个区段主要限定至少一个储存区域，以及一个或多个区域 在所述一个或多个区段的一个或多个表面区域中的至少一个表面区域之间基本上热密封的连接，其中所述一个或多个基本上热密封的连接区域和所述一个或多个区段形成整体热密封的药物储存区域。
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