摘要:
Compounds useful for the treatment of patients suffering from muscle spasms of the formula (I) ##STR1## in which R represents the radical ##STR2## in which R.sub.1, in any position on the phenyl nucleus, represents a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or the radical ##STR3## in which R.sub.2 and R.sub.3, identical or different each represents a hydrogen atom, a linear alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or form together with the nitrogen atom to which they are joined, a heterocyclic radical optionally containing another heteroatom, or NO.sub.2, or OR', R' representing hydrogen, a linear, branched or cyclic alkyl containing up to 8 carbon atoms, or aryl containing up to 14 carbon atoms, or an SR.sub.4 or S(O)R.sub.5 radical, R.sub.4 and R.sub.5 representing a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or R represents naphthyl, optionally substituted by an R.sub.1 radical, as defined above; also therapeutic compositions containing the same and method of use.
摘要:
Compounds useful for the treatment of patients suffering from muscle spasms of the formula (I) ##STR1## in which R represents the radical ##STR2## in which R.sub.1, in any position on the phenyl nucleus, represents a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or the radical ##STR3## in which R.sub.2 and R.sub.3, identical or different each represents a hydrogen atom, a linear alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or form together with the nitogen atom to which they are joined, a heterocyclic radical optionally containing another heteroatom, or NO.sub.2, or OR', R' representing hydrogen, a linear, branched or cyclic alkyl containing up to 8 carbon atoms, or aryl containing up to 14 carbon atoms, or an SR.sub.4 or S(O)R.sub.5 radical, R.sub.4 and R.sub.5 representing a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or R represents naphthyl, optionally substituted by an R.sub.1 radical, as defined above; also therapeutic compositions containing the same and method of use.
摘要:
An apparatus and method for analyzing a fluid with particle analytes, where the fluid is fed through a passageway within an optical fiber and excitation light is guided by the optical fiber across the passageway and intersects the fluid therein. The optical core is made multimode and is adapted to shape the excitation light with a uniform spatial illumination over a cross-section of the optical core and the passageway is configured relative to the optical core such that the particle analytes are exposed to substantially equal excitation light while circulating in the passageway.
摘要:
A pole adapter assembly for a pole luminaire includes an adapter body having an upper end, a lower end and an aperture for receiving a pole at the lower end, one of a raised area or a recessed area located on the body between the upper end and the lower end, a multi-point contact area along one plane of the body beneath the one of a raised area or recessed area having a first rib opposite a first set fastener, a second rib opposite a second set fastener and spaced from the first rib and the first set fastener, and at least one fastener and opposed nut disposed between the first and second ribs and the first and second set fasteners.
摘要:
A method and apparatus for managing the caching of data on an auxiliary memory of a computer. Pages of data may be cached on an auxiliary memory, such as a flash memory, at a virtual level using an identifier that does not involve a physical address of the pages on a memory. Pages may be cached on auxiliary memory that may be removable from the computer, e.g., by unplugging the memory from the computer. Page data may be encrypted and/or compressed on the auxiliary memory. An authentication indicator may be used to verify the accuracy of cached data in the case of an interrupted connection to the auxiliary memory, e.g., as a result of computer power down, hibernation, removal of the memory from the computer, etc.
摘要:
Products of formula (1), wherein R.sub.1 is particularly ##STR1## alkyl, alkylthio or alkoxy; R.sub.2 is particularly halogen, --S--R, --O--R or --C(OH)(R)--COOH, where R is alkyl or alkenyl; R.sub.3 is particularly carboxy, acyl, halogen, alkyl, alkenyl or alkylthio; and R.sub.4 is particularly --(CH.sub.2).sub.m1 --COOR.sub.4, --(CH.sub.2).sub.m1 --CONHR.sub.14, --(CH.sub.2).sub.m1 --CN, --SO.sub.2 --NH--SO.sub.2 --R.sub.14, 13 NH--SO.sub.2 --R.sub.14, --PO.sub.3 R.sub.14, or --NH--SO.sub.2 --CF.sub.3, where m1 is 0-4 and R.sub.14 is hydrogen, alkyl or alkenyl; are useful for preparing pharmaceutical compositions for treating disorders resulting from abnormal stimulation of angiotensin II receptors AT.sub.1 and AT.sub.2.
摘要:
Novel imidazoles of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts with acids and bases having an antagonistic activity against angiotensin II receptors.
摘要:
Compounds useful for the treatment of patients suffering from muscle spasms of the formula (I) ##STR1## in which R represents the radical ##STR2## in which R.sub.1, in any position on the phenyl nucleus, represents a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or the radical ##STR3## in which R.sub.2 and R.sub.3, identical or different each represents a hydrogen atom, a linear alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or form together with the nitrogen atom to which they are joined, a heterocyclic radical optionally containing another heteroatom, or NO.sub.2, or OR', R' representing hydrogen, a linear, branched or cyclic alkyl containing up to 8 carbon atoms, or aryl containing up to 14 carbon atoms, or an SR.sub.4 or S(O)R.sub.5 radical, R.sub.4 and R.sub.5 representing a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or R represents naphthyl, optionally substituted by an R.sub.1 radical, as defined above; also therapeutic compositions containing the same and method of use.