公开(公告)号：US07956060B2

公开(公告)日：2011-06-07

申请号：US10594369

申请日：2005-03-30

Applicant: Hitoshi Arai ,  Tsutomu Matsumura ,  Syoichi Isami ,  Hiroshi Ishida ,  Koji Hagihara ,  Hiroshi Umehara ,  Yoshinori Yamashita ,  Nana Oiwa ,  Yukimasa Shiotsu ,  Tomoki Naoe ,  Hitoshi Kiyoi

Inventor： Hitoshi Arai ,  Tsutomu Matsumura ,  Syoichi Isami ,  Hiroshi Ishida ,  Koji Hagihara ,  Hiroshi Umehara ,  Yoshinori Yamashita ,  Nana Oiwa ,  Yukimasa Shiotsu ,  Tomoki Naoe ,  Hitoshi Kiyoi

IPC: C07D471/04 ,  C07D471/22 ,  C07D487/04 ,  C07D239/70 ,  C07D471/00 ,  C07D487/00 ,  C07D401/00 ,  C07D403/00 ,  C07D405/00 ,  C07D409/00 ,  C07D411/00 ,  C07D413/00 ,  C07D417/00 ,  C07D419/00 ,  A61K31/505 ,  A01N43/56

CPC classification number: C07D413/04 ,  C07D413/14

Abstract: The present invention provides an antitumor agent and the like, which comprises as an active ingredient, a pyrimidine derivative represented by Formula (I): [wherein —X—Y—Z— represents —O—CR3═N— (wherein R3 represents a hydrogen atom, a substituted or unsubstituted aromatic heterocyclic group and the like) and the like, R1 represents —NR10R11 (wherein R10 and R11 may be the same or different, and each represents a hydrogen atom, substituted or unsubstituted lower alkyl and the like) and the like, R2 represents —NR13R14 (wherein R13 and R14 may be the same or different, and each represents a hydrogen atom, substituted or unsubstituted lower alkyl and the like)] or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明提供了包含作为活性成分的式（I）所示的嘧啶衍生物的抗肿瘤剂等：[其中-X-Y-Z-表示-O-CR 3 = N-（其中R 3表示 氢原子，取代或未取代的芳族杂环基等）等，R 1表示-NR 10 R 11（其中R 10和R 11可以相同或不同，各自表示氢原子，取代或未取代的低级烷基等） 等等，R 2表示-NR 13 R 14（其中R 13和R 14可以相同或不同，各自表示氢原子，取代或未取代的低级烷基等）]或其药学上可接受的盐。

公开(公告)号：US20100237557A1

公开(公告)日：2010-09-23

申请号：US12659651

申请日：2010-03-16

Applicant: Masashi Hara ,  Tatsunori Kaneko ,  Hitoshi Arai ,  Ryota Yamagishi

Inventor： Masashi Hara ,  Tatsunori Kaneko ,  Hitoshi Arai ,  Ryota Yamagishi

IPC: B65H5/26 ,  B65H5/34

CPC classification number: B65H5/26 ,  B65H5/38 ,  B65H7/00 ,  B65H9/006 ,  B65H2511/414 ,  B65H2513/50 ,  B65H2557/23 ,  B65H2220/01 ,  B65H2220/02

Abstract: Configuration with paired register rollers cooperative with a downstream head unit on a circulation route to register a print sheet, a feed route extending up to the register rollers, and feeder elements controllable for a downstream feed of print sheet along part of the feed route to the register rollers, the feeder elements being controllable for a change of feed speed or acceleration in accordance with information on a back tension of a print sheet on the circulation route.

Abstract translation: 具有成对的定位辊的配置与循环路线上的下游头单元协作以记录打印纸，向上延伸到对准辊的进给路径以及可控制的进给器元件，用于沿着进给路线的一部分的下游进给打印纸 记录辊，馈送元件可根据关于循环路线上的打印片材的背张力的信息而被控制以改变进给速度或加速度。

公开(公告)号：US20100190775A1

公开(公告)日：2010-07-29

申请号：US12602312

申请日：2008-06-02

Applicant: Nobumasa Otsubo ,  Yukihito Tsukumo ,  Kenji Uchida ,  Yuichi Matsumoto ,  Kyoichiro Iida ,  Hidenori Takada ,  Fumitake Takizawa ,  Hitoshi Arai ,  Shuko Okazaki ,  Takamichi Imaizumi

Inventor： Nobumasa Otsubo ,  Yukihito Tsukumo ,  Kenji Uchida ,  Yuichi Matsumoto ,  Kyoichiro Iida ,  Hidenori Takada ,  Fumitake Takizawa ,  Hitoshi Arai ,  Shuko Okazaki ,  Takamichi Imaizumi

IPC: A61K31/551 ,  C07D487/14 ,  C07K1/107 ,  A61P17/06 ,  A61P17/00 ,  A61P29/00 ,  A61P37/00 ,  A61P17/04

CPC classification number: C07D487/14

Abstract: The invention provides a pyrimidodiazepinone derivative represented by the general formula (I) [wherein n represents 1 or 2, Z represents a hydrogen atom or the like, R1 and R2 may be the same or different, and each represents a hydrogen atom or the like, A represents a bond, (CH2)m (wherein m represents an integer of 1 to 4), optionally substituted phenylene, optionally substituted pyridinediyl, or C═O, R3 represents a hydrogen atom, optionally substituted lower alkyl, or the like, and R4 represents a hydrogen atom or the like], or a pharmaceutically acceptable salt thereof or the like.

Abstract translation: 本发明提供由通式（I）表示的嘧啶并二氮杂酮衍生物[其中n表示1或2，Z表示氢原子等，R 1和R 2可以相同或不同，表示氢原子等 ，A表示键，（CH 2）m（其中m表示1至4的整数），任选取代的亚苯基，任选取代的吡啶二基或C = O，R 3表示氢原子，任选取代的低级烷基等， R 4表示氢原子等]或其药学上可接受的盐等。

公开(公告)号：US20090039588A1

公开(公告)日：2009-02-12

申请号：US12187674

申请日：2008-08-07

Applicant: Masao SUZUKI ,  Hitoshi Arai

Inventor： Masao SUZUKI ,  Hitoshi Arai

IPC: B65H5/00

CPC classification number: B65H7/02 ,  B65H9/008 ,  B65H2511/514 ,  B65H2513/108 ,  B65H2513/51 ,  B65H2513/512 ,  B65H2701/1311 ,  B65H2701/1313 ,  B65H2220/02 ,  B65H2220/01

Abstract: In a paper feed system where a first paper feed mechanism takes out and transfers one by one a plurality of papers placed on a paper feed table in a stack and a second paper feed mechanism transfers the papers transferred by the first paper feed mechanism to an image forming section at a predetermined timing. A paper edge detector is provided between the first and second paper feed mechanisms to detect an edge of the paper, and the first paper feed mechanism is controlled to transfer the papers at a first speed and then at a second speed not higher than the first speed when the paper edge detector detects the leading edge of the paper, the second speed being determined on the basis of the timing at which the leading edge of the paper is detected.

Abstract translation: 在供纸系统中，第一供纸机构取出并放置放置在堆叠中的供纸台上的多张纸张，第二送纸机构将由第一供纸机构传送的纸张传送到图像 形成部。 纸边缘检测器设置在第一和第二进纸机构之间以检测纸张的边缘，并且第一送纸机构被控制成以第一速度然后以不高于第一速度的第二速度传送纸张 当纸张边缘检测器检测到纸张的前缘时，基于检测到纸张前缘的定时来确定第二速度。

公开(公告)号：US07357970B2

公开(公告)日：2008-04-15

申请号：US11012336

申请日：2004-12-16

Applicant: Daisuke Yoshitoku ,  Koji Mishima ,  Kenji Yamaga ,  Hitoshi Arai

Inventor： Daisuke Yoshitoku ,  Koji Mishima ,  Kenji Yamaga ,  Hitoshi Arai

IPC: B32B3/02

CPC classification number: G11B7/257 ,  G11B7/24038 ,  G11B7/243 ,  G11B2007/24304 ,  G11B2007/2432 ,  Y10T428/21

Abstract: An optical recording medium comprising: a substrate 11; and a recording layer 12, formed on substrate 11; and characterized in that recording layer 12 contains palladium oxide as the main component and contains oxygen at an amount of 19 atom % to 61 atom %.

Abstract translation: 一种光记录介质，包括：基板11; 以及形成在基板11上的记录层12; 其特征在于记录层12含有氧化钯作为主要成分并含有19原子％至61原子％的氧。

公开(公告)号：US20070008359A1

公开(公告)日：2007-01-11

申请号：US11477917

申请日：2006-06-30

Applicant: Masao Suzuki ,  Hitoshi Arai

Inventor： Masao Suzuki ,  Hitoshi Arai

IPC: B41J29/38

CPC classification number: B41J29/393 ,  B41J2/04508 ,  B41J2/04573 ,  B41J2/04586 ,  B41J2/155

Abstract: Disclosed herein is an inkjet recording apparatus including plural recording heads, each of which has plural nozzles, which selectively discharge ink, arranged at a predetermined pitch in a line, the inkjet recording apparatus being constructed such that the plural recording heads are arranged in a zigzag fashion such that the disposition direction of the nozzles is parallel with a main scanning direction, the respective ends of two adjacent recording heads are overlapped with each other to form a joint part, and ink from the selected nozzles of the respective recording heads is discharged on print paper fed along a sub scanning direction at a predetermined timing corresponding to the positions of the respective recording heads in the sub scanning direction such that an in-line image continuous in the main scanning direction is formed on the print paper, wherein the inkjet recording apparatus further includes a control unit for controlling the driving operation of the respective nozzles at the joint part depending upon the dispositional relation between the nozzles of the two recording heads at the joint part in the main scanning direction.

Abstract translation: 本发明公开了一种喷墨记录装置，包括多个记录头，每个记录头具有多个喷嘴，其选择性地以一定的间距排成一排排墨，喷墨记录装置被构造为使得多个记录头以锯齿形排列 使得喷嘴的配置方向与主扫描方向平行，两个相邻的记录头的相应端部彼此重叠以形成接合部分，并且来自各个记录头的选定喷嘴的墨水被排出到 在与副扫描方向上的各个记录头的位置相对应的预定定时沿着副扫描方向馈送的打印纸，使得在打印纸上形成在主扫描方向上连续的在线图像，其中喷墨记录 装置还包括用于控制各个喷嘴的驱动操作的控制单元 根据主扫描方向上的接合部处的两个记录头的喷嘴之间的配置关系，在接合部处。

公开(公告)号：US20060239999A1

公开(公告)日：2006-10-26

申请号：US10525326

申请日：2003-08-22

Applicant: Mayumi Saki ,  Hiromi Nonaka ,  Hiromasa Miyaji ,  Naoko Hiura ,  Haruhiko Manabe ,  Tsotomu Matsumura ,  Hitoshi Arai ,  Katsutoshi Sasaki ,  Cjoei Kobatake ,  Kyoichiro Iida ,  Takeshi Kuboyama

Inventor： Mayumi Saki ,  Hiromi Nonaka ,  Hiromasa Miyaji ,  Naoko Hiura ,  Haruhiko Manabe ,  Tsotomu Matsumura ,  Hitoshi Arai ,  Katsutoshi Sasaki ,  Cjoei Kobatake ,  Kyoichiro Iida ,  Takeshi Kuboyama

IPC: A61K48/00 ,  A61K39/395 ,  A61K31/55

CPC classification number: A61K31/519 ,  A61K31/55 ,  A61K31/7088 ,  C07D403/06

Abstract: The present invention provides an agent for prevention and/or treatment of asthma comprising a substance capable of suppressing the function involved in signal transduction of GPR4 as an active ingredient. It also provides an agent for prevention and/or treatment of asthma which comprises a nitrogen-containing tricyclic compound represented by the formula (I) or a quaternary ammonium salt thereof, or a pharmaceutically acceptable salt thereof; [wherein R1 represents a substituted or unsubstituted lower alkyl, or the like; R2 represents hydrogen, a substituted or unsubstituted lower alkyl, or the like; R3 and R4 are the same or different and each represents hydrogen, lower alkyl, or the like; n represents 0 or 1; X represents —(CH2)2—, or the like; and Y represents the formula (II) (wherein W represents CH or a nitrogen atom; Z1 and Z2 are the same or different and each represents hydrogen, a substituted or unsubstituted lower alkyl, or the like; and Z3 represents hydrogen, a substituted or unsubstituted lower alkyl, or the like)] as an active ingredient.

Abstract translation: 本发明提供了用于预防和/或治疗哮喘的药剂，其包含能够抑制作为活性成分的GPR4的信号转导所涉及的功能的物质。 它还提供了一种预防和/或治疗哮喘的药剂，其包含由式（I）表示的含氮三环化合物或其季铵盐或其药学上可接受的盐; [其中R 1表示取代或未取代的低级烷基等; R 2表示氢，取代或未取代的低级烷基等; R 3和R 4相同或不同，各自表示氢，低级烷基等; n表示0或1; X表示 - （CH 2 2）2 - 等; Y表示式（II）（其中W表示CH或氮原子; Z 1和Z 2相同或不同，各自表示氢，取代或 未取代的低级烷基等; Z 3表示氢，取代或未取代的低级烷基等）作为活性成分。

公开(公告)号：US20050177767A1

公开(公告)日：2005-08-11

申请号：US10871175

申请日：2004-06-18

Applicant: Hodaka Furuya ,  Hitoshi Arai ,  Tomohiro Shinohara

Inventor： Hodaka Furuya ,  Hitoshi Arai ,  Tomohiro Shinohara

IPC: G06F3/06 ,  G06F11/00 ,  G06F11/14 ,  G06F12/00

CPC classification number: G06F11/1451 ,  G06F11/1448 ,  G06F11/1456 ,  G06F11/1469 ,  Y10S707/99953 ,  Y10S707/99955

Abstract: On the basis of a priority table in which a plurality of group restoration priorities respectively corresponding to a plurality of element groups are recorded, the priority-based backup part backs up all of the backup object elements belonging to a first element group in a first continuous region which is a continuous recording region on a tape recording medium, and backs up all of the backup object elements belonging to a second element group whose group restoration priority is lower than that of said first element group in a second continuous region which is located on the tape tail end side of said first continuous region.

Abstract translation: 基于分配对应于多个元素组的多个组恢复优先级的优先级表，基于优先级的备份部分将属于第一元素组的所有备份对象元素备份在第一连续 区域，其是磁带记录介质上的连续记录区域，并且在第二连续区域中备份属于第二元素组的所有备份对象元素，其中组恢复优先级低于所述第一元素组的备份对象元素 所述第一连续区域的磁带尾端侧。

公开(公告)号：US5981558A

公开(公告)日：1999-11-09

申请号：US133614

申请日：1998-08-13

Applicant: Hitoshi Arai ,  Yutaka Kanda ,  Hiroyuki Yamaguchi ,  Tadashi Ashizawa ,  Chikara Murakata ,  Shun-ichi Ikeda ,  Tatsuya Tamaoki

Inventor： Hitoshi Arai ,  Yutaka Kanda ,  Hiroyuki Yamaguchi ,  Tadashi Ashizawa ,  Chikara Murakata ,  Shun-ichi Ikeda ,  Tatsuya Tamaoki

IPC: C07D513/18 ,  C07H15/26 ,  C07D513/08 ,  A61K31/425

CPC classification number: C07D513/18 ,  C07H15/26

Abstract: DC107 derivatives represented by formula (I) or pharmaceutically acceptable salts thereof which have antimicrobial activity and antitumor activity are provided: ##STR1## wherein R.sup.1 represents hydrogen, lower alkoxyalkyl, aralkyloxyalkyl, lower alkoxyalkoxyalkyl, lower alkoxyalkoxyalkoxyalkyl, aralkyl, tetrahydropyranyl, COR.sup.4, or the like; R.sup.2 represents hydrogen or COR.sup.6 ; R.sup.3 represents --CH.sub.2 OCOR.sup.7, phthalimidomethyl, or the like; and W represents oxygen or NR.sup.8 (wherein R.sup.8 represents hydroxy, lower alkoxy, lower alkenyloxy, aralkyloxy, substituted or unsubstituted arylsulfonylamino, or lower alkoxycarbonylamino).

Abstract translation: 提供了具有抗微生物活性和抗肿瘤活性的由式​​（I）表示的DC107衍生物或其药学上可接受的盐，其中R1表示氢，低级烷氧基烷基，芳烷氧基烷基，低级烷氧基烷氧基烷基，低级烷氧基烷氧基烷氧基烷基，芳烷基，四氢吡喃基，COR4等; R2表示氢或COR6; R3表示-CH2OCOR7，苯二甲酰亚氨基甲基等; W表示氧或NR8（其中R8表示羟基，低级烷氧基，低级烯氧基，芳烷氧基，取代或未取代的芳基磺酰基氨基或低级烷氧基羰基氨基）。

公开(公告)号：US5565284A

公开(公告)日：1996-10-15

申请号：US256862

申请日：1994-08-04

Applicant: Keiji Koga ,  Hisashi Suzuki ,  Masanori Kaya ,  Hitoshi Arai ,  Tsuneo Kagotani ,  Yousuke Miyaki

Inventor： Keiji Koga ,  Hisashi Suzuki ,  Masanori Kaya ,  Hitoshi Arai ,  Tsuneo Kagotani ,  Yousuke Miyaki

IPC: H01M4/04 ,  H01M4/62 ,  H01M6/10 ,  H01M4/02

CPC classification number: H01M4/0409 ,  H01M4/04 ,  H01M4/0404 ,  H01M4/0414 ,  H01M4/0416 ,  H01M4/0419 ,  H01M4/043 ,  H01M4/0435 ,  H01M4/621 ,  H01M2006/106

Abstract: A main object of the invention is to provide a lithium secondary cell which experiences minimal capacity deterioration upon repetitive charge-discharge cycles.The lithium secondary cell of the invention is characterized in that a negative and/or positive electrode material is bonded to a current collector surface by a binder containing a crosslinked polymer or formed by coating to a current collector a composition comprising an active material and a polymer binder containing a fluorinated polymer which is curable upon exposure to radiation, followed by radiation curing treatment.

Abstract translation: PCT No.PCT / JP93 / 01883 Sec。 371日期：1994年8月4日 102（e）日期1994年8月4日PCT 1993年12月24日PCT公布。 公开号WO94 / 15374 日期：1994年7月7日本发明的主要目的是提供一种锂二次电池，其在重复的充放电循环中经历最小的容量劣化。 本发明的锂二次电池的特征在于，负极材料和/或正极材料通过含有交联聚合物的粘合剂结合到集电器表面，或者通过将含有活性材料和聚合物的组合物涂布到集电体上而形成 含有氟化聚合物的粘合剂，其在暴露于辐射时可固化，然后进行辐射固化处理。