公开(公告)号：US20120245345A1

公开(公告)日：2012-09-27

申请号：US13511292

申请日：2010-12-17

Applicant: Bérangère Gaucher ,  Franck Hubert Danel ,  XiaoHu Tang ,  Tong Xie ,  Lin Xu

Inventor： Bérangère Gaucher ,  Franck Hubert Danel ,  XiaoHu Tang ,  Tong Xie ,  Lin Xu

IPC: C07D491/052 ,  C07D498/14 ,  C07D495/04 ,  C07D513/04

CPC classification number: C07D513/04 ,  C07D491/04 ,  C07D491/052 ,  C07D491/147 ,  C07D495/04 ,  C07D498/04 ,  C07D498/14

Abstract: Compound of formula (I): wherein A1 represents —O—, —S— or —N—R3; A2 represents —CH2—, —O—, —N—R4, —C(═O)— or —CH(O—R4)—; A3 represents C3-C8cycloalkylene; saturated and unsaturated 4 to 8-membered heterocyclodiyl with 1, 2 or 3 heteroatoms selected from nitrogen, oxygen and sulphur, which group A3 is unsubstituted or substituted; A4 represents C1-C4alkylene, C2-C4alkenylene, >C═O or a group selected from —C2H4NH—, —C2H4O—, and —C2H4S— being linked to the adjacent NR5-group via the carbon atom; and G represents aryl or heteroaryl, which is un-substituted or substituted and R1 and R2 independently of one another, represent hydrogen or a substituent selected from hydroxy, halogen, mercapto, cyano, nitro, C1-C6alkyl, C1-C6alkoxy, C1-C6alkylthio, C1-C6alkylcarbonyloxy, C1-C6alkylsulfonyloxy, C1-C6heteroalkylcarbonyloxy, C5-C6heterocyclylcarbonyloxy, C1-C6heteroalkoxy, wherein heteroalkyl, heteroalkoxy groups or heterocyclyl comprise 1, 2 or 3 heteroatoms selected from nitrogen, oxygen and sulphur, in which substituents the alkyl moieties are unsubstituted or further substituted; R3, R4 and R5 independently of one another, represent hydrogen or C1-C6alkyl; X1 and X2 independently of one another, represent a nitrogen atom or CR2, with the proviso that at least one of X1 and X2 represents a nitrogen atom; m is 1; and the (CH2)m moiety is optionally substituted by C1-C4alkyl; halogen, carboxy, hydroxy, C1-C4alkoxy, C1-C4-alkylcarbonyloxy, amino, mono- or di-(C1-C4alkyl)amino or acylamino n is 0, 1 or 2 or pharmaceutically acceptable salt thereof are valuable for use as a medicament for the treatment of bacterial infections.

Abstract translation: 式（I）化合物：其中A1表示-O - ， - S-或-N-R 3; A 2表示-CH 2 - ， - O - ， - N-R 4，-C（= O） - 或-CH（O-R 4） - ; A3表示C3-C8亚环烷基; 饱和和不饱和的4至8元杂环基与1,2或3个选自氮，氧和硫的杂原子，该基团A3为未取代或取代的; A4表示C1-C4亚烷基，C2-C4亚烯基，> C = O或选自-C2H4NH-，-C2H4O-和-C2H4S-的基团，其通过碳原子连接到相邻的NR5-基团; 并且G表示未取代或取代的芳基或杂芳基，R 1和R 2彼此独立地表示氢或选自羟基，卤素，巯基，氰基，硝基，C 1 -C 6烷基，C 1 -C 6烷氧基， C 1 -C 6烷硫基，C 1 -C 6烷基羰基氧基，C 1 -C 6烷基磺酰氧基，C 1 -C 6杂烷基羰氧基，C 5 -C 6杂环羰基氧基，C 1 -C 6杂烷氧基，其中杂烷基，杂烷氧基或杂环基包含1,2或3个选自氮，氧和硫的杂原子，其中烷基部分 是未取代的或进一步取代的; R 3，R 4和R 5彼此独立地表示氢或C 1 -C 6烷基; X 1和X 2彼此独立地表示氮原子或CR 2，条件是X 1和X 2中的至少一个表示氮原子; m为1; （CH 2）m部分任选被C 1 -C 4烷基取代; 卤素，羧基，羟基，C 1 -C 4烷氧基，C 1 -C 4烷基羰基氧基，氨基，单 - 或二 - （C 1 -C 4烷基）氨基或酰氨基n是0,1或2或其药学上可接受的盐对于用作药物是有价值的 用于治疗细菌感染。

公开(公告)号：US20120108773A1

公开(公告)日：2012-05-03

申请号：US13284744

申请日：2011-10-28

Applicant: Chao Wang ,  Chuanqing Li ,  Guozhu Yu ,  Aimin Liang ,  Jie Zhang ,  Lin Xu ,  Pengfei Lv ,  Huiling Liu

Inventor： Chao Wang ,  Chuanqing Li ,  Guozhu Yu ,  Aimin Liang ,  Jie Zhang ,  Lin Xu ,  Pengfei Lv ,  Huiling Liu

IPC: C08F36/08 ,  C08F4/649 ,  C08F2/00

CPC classification number: C08F36/08 ,  C08F136/08 ,  C08F4/6494

Abstract: Disclosed are catalyst compositions for isoprene polymerization formed from components comprising (A) at least one titanium halide; (B) at least one organic aluminum compound comprising at least one alkyl aluminum of formula AlR3, wherein each of the three Rs is independently chosen from linear and branched C1-6 alkyl groups; and (C) at least one electron donor comprising at least one polyether compound of formula (I) and/or at least one tetrahydro-furfuryl ether compound of formula (II). Also disclosed are processes for preparation of the catalyst compositions and processes using the catalyst compositions for isoprene polymerization.

Abstract translation: 公开了由组分（A）至少一种卤化钛组成的异戊二烯聚合催化剂组合物， （B）至少一种包含至少一种式AlR 3的烷基铝的有机铝化合物，其中三个R 3中的每一个独立地选自直链和支链C 1-6烷基; 和（C）包含至少一种式（I）的聚醚化合物和/或至少一种式（II）的四氢糠基醚化合物的至少一种电子给体。 还公开了制备催化剂组合物的方法和使用该催化剂组合物用于异戊二烯聚合的方法。

公开(公告)号：US08160999B2

公开(公告)日：2012-04-17

申请号：US11610480

申请日：2006-12-13

Applicant: Qi Jin ,  Hui Liao ,  Sriram K. Padmanabhan ,  Lin Xu

Inventor： Qi Jin ,  Hui Liao ,  Sriram K. Padmanabhan ,  Lin Xu

IPC: G06F7/00

CPC classification number: G06F17/30454

Abstract: Methods and systems for implementing a splitter operation in an extract, transform, and load (ETL) process are provided. In one implementation, the method includes receiving a data flow including a splitter operation, and generating an execution plan graph based on the data flow. The execution plan graph includes structured query language (SQL) code for implementing the splitter operation, in which the structured query language (SQL) code is respectively executable among database servers associated with different vendors.

Abstract translation: 提供了在提取，转换和加载（ETL）过程中实现分离器操作的方法和系统。 在一个实现中，该方法包括接收包括分离器操作的数据流，以及基于数据流生成执行计划图。 执行计划图包括用于实现分离器操作的结构化查询语言（SQL）代码，其中结构化查询语言（SQL）代码可以分别在与不同供应商相关联的数据库服务器之间执行。

公开(公告)号：US08099725B2

公开(公告)日：2012-01-17

申请号：US11548659

申请日：2006-10-11

Applicant: Qi Jin ,  Hui Liao ,  Lin Xu

Inventor： Qi Jin ,  Hui Liao ,  Lin Xu

IPC: G06F9/44 ,  G06F9/45

CPC classification number: G06F17/30421 ,  G06F17/30404

Abstract: Methods, computer program products, and system for generating code for an extract, transform, and load (ETL) data flow are provided. In one implementation, the method includes receiving an ETL data flow representing a logical transformation and flow of data, placing a staging table at a pre-determined location in the ETL data flow to reduce a total number of staging tables required by the transformation, and generating code for the transformation based on the ETL data flow including the staging table placed at the pre-determined location.

Abstract translation: 提供了方法，计算机程序产品和用于生成提取，转换和加载（ETL）数据流的代码的系统。 在一个实现中，该方法包括接收表示逻辑变换和数据流的ETL数据流，将历元表置于ETL数据流中的预定位置以减少转换所需的分段表的总数，以及 基于包括放置在预定位置的登台表的ETL数据流生成用于转换的代码。

公开(公告)号：US20110307875A1

公开(公告)日：2011-12-15

申请号：US12813404

申请日：2010-06-10

Applicant: Lin Xu ,  Weiping Hu ,  Yongkang Zhu

Inventor： Lin Xu ,  Weiping Hu ,  Yongkang Zhu

IPC: G06F9/45

CPC classification number: G06F8/437

Abstract: Embodiments are directed to tracking variable location information in optimized code and efficiently collecting and storing reaching definition information. A computer system receives a portion of source code at a compiler, where the compiler is configured to compile and optimize the source code for execution. The computer system tags selected variables in the source code with a tag, where the tag is configured to provide location information for the variable. The computer system optimizes the received portion of source code including changing at least one of the tagged variables. The computer system also tracks the tagged variables as the variables are changed by the compiler during code optimization and persists the variable location information, so that the persisted variable location information is available to other compiler components.

Abstract translation: 实施例涉及在优化代码中跟踪可变位置信息并有效地收集和存储到达定义信息。 计算机系统在编译器处接收一部分源代码，其中编译器被配置为编译和优化用于执行的源代码。 计算机系统使用标签将源代码中的选定变量标记，其中标签被配置为提供变量的位置信息。 计算机系统优化所接收的源代码部分，包括改变至少一个标记变量。 计算机系统还跟踪标记的变量，因为编码器在代码优化期间改变了变量，并且持续存在变量位置信息，使得持久变量位置信息可用于其他编译器组件。

公开(公告)号：US20110257107A1

公开(公告)日：2011-10-20

申请号：US13169604

申请日：2011-06-27

Applicant: Shey-Shing Sheu ,  Marion W. Anders ,  Lin Xu ,  Virendra K. Sharma ,  Dhanajaya Nauduri

Inventor： Shey-Shing Sheu ,  Marion W. Anders ,  Lin Xu ,  Virendra K. Sharma ,  Dhanajaya Nauduri

IPC: A61K38/06 ,  A61K31/164 ,  C12N5/00 ,  A61P39/06 ,  C07C323/59 ,  C07D277/06 ,  A61K31/223 ,  A61K31/426 ,  C07C323/60 ,  C07K5/083

CPC classification number: A61K31/198 ,  A61K9/0019 ,  A61K38/063

Abstract: Disclosed are compounds containing single amino acids, peptides, or derivatives thereof which are selectively delivered to the mitochondria of a cell. Compounds of the invention exhibit antioxidant activity thereby reducing reactive oxygen species in cells. These compounds are useful for inhibiting oxidative stress-induced cell injury or death both in vivo and ex vivo. In addition, methods for the synthesis of these compounds are disclosed.

Abstract translation: 公开了含有单个氨基酸，肽或其衍生物的化合物，其被选择性递送至细胞的线粒体。 本发明的化合物表现出抗氧化活性，从而减少细胞中的活性氧。 这些化合物可用于在体内和体外抑制氧化应激诱导的细胞损伤或死亡。 此外，公开了合成这些化合物的方法。

公开(公告)号：US20110157030A1

公开(公告)日：2011-06-30

申请号：US12651411

申请日：2009-12-31

Applicant: Lin Xu

Inventor： Lin Xu

IPC: G06F3/041

CPC classification number: G06F3/0416 ,  G06F3/0421

Abstract: A method for detecting one or more objects on a touch screen, wherein the touch screen has a plurality of transmitters and receivers, comprises the following steps: serializing data signals into a group data signal corresponding to the transmitters and the receivers of the touch screen; transmitting and deserializing the group data signal to the transmitters and the receivers; receiving receiver data indicative of the detection of one or more objects on the touch screen; serializing the receiver data into serialized common data signal; and outputting the common data signal, wherein the common data signal is indicative of the detected objects on the touch screen.

Abstract translation: 一种用于检测触摸屏上的一个或多个对象的方法，其中所述触摸屏具有多个发射器和接收器，包括以下步骤：将数据信号串行化成对应于触摸屏的发射器和接收器的组数据信号; 将组数据信号发射和反序列化到发射机和接收机; 接收指示所述触摸屏上的一个或多个对象的检测的接收器数据; 将接收机数据串行化为串行化的公共数据信号; 并输出公共数据信号，其中公共数据信号指示在触摸屏上检测到的对象。

公开(公告)号：US20100132887A2

公开(公告)日：2010-06-03

申请号：US12435545

申请日：2009-05-05

Applicant: Vincent Donnelly ,  Demetre Economou ,  Paul Ruchhoeft ,  Lin Xu ,  Sri Vemula ,  Manish Jain

Inventor： Vincent Donnelly ,  Demetre Economou ,  Paul Ruchhoeft ,  Lin Xu ,  Sri Vemula ,  Manish Jain

IPC: C23F1/08 ,  B05C5/02

CPC classification number: B29D11/00365 ,  B82Y30/00

Abstract: A method is provided for creating a plurality of substantially uniform nano-scale features in a substantially parallel manner in which an array of micro-lenses is positioned on a surface of a substrate, where each micro-lens includes a hole such that the bottom of the hole corresponds to a portion of the surface of the substrate. A flux of charged particles, e.g., a beam of positive ions of a selected element, is applied to the micro-lens array. The flux of charged particles is focused at selected focal points on the substrate surface at the bottoms of the holes of the micro-lens array. The substrate is tilted at one or more selected angles to displace the locations of the focal points across the substrate surface. By depositing material or etching the surface of the substrate, several substantially uniform nanometer sized features may be rapidly created in each hole on the surface of the substrate in a substantially parallel manner.

Abstract translation: 提供了一种用于以基本上平行的方式产生多个基本均匀的纳米尺度特征的方法，其中微透镜阵列位于基底的表面上，其中每个微透镜包括孔，使得底部 孔对应于基板表面的一部分。 带电粒子的通量，例如所选元素的正离子束，被施加到微透镜阵列。 带电粒子的通量被聚焦在微透镜阵列的孔的底部的基底表面上的选定的焦点处。 衬底以一个或多个选定的角度倾斜，以便将焦点的位置移动穿过衬底表面。 通过沉积材料或蚀刻衬底的表面，可以以基本上平行的方式在衬底的表面上的每个孔中快速产生几个基本均匀的纳米尺寸的特征。

公开(公告)号：US20090298782A1

公开(公告)日：2009-12-03

申请号：US12097948

申请日：2006-12-18

Applicant: Shey-Shing Sheu ,  Marion W. Anders ,  Lin Xu ,  Virendra K. Sharma ,  Dhananjaya Nauduri

Inventor： Shey-Shing Sheu ,  Marion W. Anders ,  Lin Xu ,  Virendra K. Sharma ,  Dhananjaya Nauduri

IPC: A61K38/05 ,  A61K31/22 ,  A61K31/425 ,  C12N5/02

CPC classification number: A61K31/198 ,  A61K9/0019 ,  A61K38/063

Abstract: Disclosed are compounds containing single amino acids, peptides, or derivatives thereof which are selectively delivered to the mitochondria of a cell. Compounds of the invention exhibit antioxidant activity thereby reducing reactive oxygen species in cells. These compounds are useful for inhibiting oxidative stress-induced cell injury or death both in vivo and ex vivo. In addition, methods for the synthesis of these compounds are disclosed.

Abstract translation: 公开了含有单个氨基酸，肽或其衍生物的化合物，其被选择性递送至细胞的线粒体。 本发明的化合物表现出抗氧化活性，从而减少细胞中的活性氧。 这些化合物可用于在体内和体外抑制氧化应激诱导的细胞损伤或死亡。 此外，公开了合成这些化合物的方法。

公开(公告)号：US07606587B2

公开(公告)日：2009-10-20

申请号：US10528403

申请日：2002-09-20

Applicant: Lin Xu ,  Juha-Pekka Luoma ,  Sinikka Sarkkinen ,  Rod Walsh

Inventor： Lin Xu ,  Juha-Pekka Luoma ,  Sinikka Sarkkinen ,  Rod Walsh

IPC: H04B7/00 ,  H04M1/663

CPC classification number: H04W4/06 ,  H04W4/08 ,  H04W60/00 ,  H04W72/005

Abstract: The invention relates to a mechanism for performing multicast transmission in a cellular network. In order to enable establishment of resources only in cells containing members of the multicast group and to avoid congestion on the uplink channel, a multicast service notification is transmitted to mobile stations, thereby informing members of the multicast group of an upcoming multicast session. The moment for a response to said multicast service notification is selected in the mobile stations and a presence report is sent from at least one of said mobile stations at the response moment of said at least one mobile station. The presence report or reports are received within a radio access network, and radio resources are established for multicast transmission in a cell of the cellular network when the presence report(s) received in said cell meet(s) predetermined criteria.

Abstract translation: 本发明涉及用于在蜂窝网络中执行多播传输的机制。 为了仅在包含多播组的成员的小区中建立资源，并且为了避免上行链路信道的拥塞，将多播服务通知发送到移动台，从而向多播组的成员通知即将到来的多播会话。 在移动台中选择响应于所述多播服务通知的时刻，并且在所述至少一个移动台的响应时刻，从至少一个所述移动站发送存在报告。 在无线电接入网络内接收存在报告或报告，并且当在所述小区中接收到的存在报告满足预定标准时，为蜂窝网络的小区中的多播传输建立无线电资源。