公开(公告)号：US08255972B2

公开(公告)日：2012-08-28

申请号：US12134933

申请日：2008-06-06

申请人： Alain C. Azagury ,  Murthy V. Devarakonda ,  Nikolai Joukov ,  Manoj Kumar ,  Konstantinos Magoutis ,  Birgit M. Pfitzmann ,  Norbert G. Vogl

发明人： Alain C. Azagury ,  Murthy V. Devarakonda ,  Nikolai Joukov ,  Manoj Kumar ,  Konstantinos Magoutis ,  Birgit M. Pfitzmann ,  Norbert G. Vogl

IPC分类号： G06F17/00

CPC分类号： G06F21/604 ,  G06F2221/2101

摘要： A method, system, computer program product, and computer program storage device for transforming a high-level policy associated with a high layer to a low-level policy associated with a low layer. Mapping between high-level objects in a high layer and low-level objects in a low layer is derived by an automated discovery tool. The high-level policy is mapped to the low-level policy according to the mapping (e.g., by substituting the high-level objects with the low-level objects and by performing a syntax transformation). In one embodiment, a low-level policy is transformed to a high-level policy according to the mapping. As exemplary embodiments, policy transformations in traffic shaping and data retention are disclosed.

摘要翻译： 一种用于将与高层相关联的高级策略变换为与低层相关联的低级策略的方法，系统，计算机程序产品和计算机程序存储设备。 高层的高层对象与低层对象之间的映射是通过自动发现工具得出的。 高级策略根据映射映射到低级策略（例如，通过用低级对象替换高级对象，并通过执行语法转换）。 在一个实施例中，根据映射将低级策略转换为高级策略。 作为示例性实施例，公开了流量整形和数据保持中的策略转换。

公开(公告)号：US08176268B2

公开(公告)日：2012-05-08

申请号：US12813398

申请日：2010-06-10

申请人： Rajiv Kottomtharayil ,  Parag Gokhale ,  Anand Prahlad ,  Manoj Kumar ,  David Ngo ,  Varghese Devassy

发明人： Rajiv Kottomtharayil ,  Parag Gokhale ,  Anand Prahlad ,  Manoj Kumar ,  David Ngo ,  Varghese Devassy

IPC分类号： G06F13/00

CPC分类号： G06F3/0619 ,  G06F3/0617 ,  G06F3/0635 ,  G06F3/065 ,  G06F3/0655 ,  G06F3/067 ,  G06F3/0689 ,  G06F11/1448 ,  G06F11/1464 ,  G06F11/1469 ,  G06F17/30321 ,  G06F17/30864 ,  H04L67/1097 ,  Y10S707/99953 ,  Y10S707/99955

摘要： Methods and systems are described for performing storage operations on electronic data in a network. In response to the initiation of a storage operation and according to a first set of selection logic, a media management component is selected to manage the storage operation. In response to the initiation of a storage operation and according to a second set of selection logic, a network storage device to associate with the storage operation. The selected media management component and the selected network storage device perform the storage operation on the electronic data.

摘要翻译： 描述了用于对网络中的电子数据执行存储操作的方法和系统。 响应于开始存储操作并且根据第一组选择逻辑，选择介质管理组件来管理存储操作。 响应于开始存储操作并且根据第二组选择逻辑，与存储操作相关联的网络存储设备。 所选择的媒体管理组件和所选择的网络存储设备对电子数据执行存储操作。

公开(公告)号：US20110195059A1

公开(公告)日：2011-08-11

申请号：US12810004

申请日：2008-12-16

申请人： Christopher C. Barnett ,  Manoj Kumar ,  Gregory M. Whited

发明人： Christopher C. Barnett ,  Manoj Kumar ,  Gregory M. Whited

IPC分类号： A01N63/02 ,  A01P1/00

CPC分类号： A01N63/02 ,  C11D3/386 ,  C11D3/38636

摘要： The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm.

摘要翻译： 本发明提供从表面去除生物膜的方法，组合物和试剂盒。 本文描述的方法包括同时或顺序地将表面上的生物膜同时或顺序施用过水解酶和其它酶（例如蛋白酶，葡聚糖酶，酯酶，甘露聚糖酶，磷脂酶，纤维素酶和/或淀粉酶）的混合物，以去除 生物膜。

公开(公告)号：US20110066457A1

公开(公告)日：2011-03-17

申请号：US12559388

申请日：2009-09-14

申请人： Yuan Chi Chang ,  Manoj Kumar ,  Chung-Sheng Li

发明人： Yuan Chi Chang ,  Manoj Kumar ,  Chung-Sheng Li

IPC分类号： G06Q10/00 ,  G06F9/54 ,  G06F17/30 ,  G06F15/16

CPC分类号： G06Q10/10

摘要： Systems, methods and articles of manufacture are disclosed for building and executing analytics solutions. Such a solution may provide a comprehensive analytics solution (e.g., a risk assessment, fraud detection solution, dynamic operational risk evaluations, regulatory compliance assessments, etc.). The analytics solution may perform an analytics task using operational data distributed across a variety of independently created and governed data repositories in different departments of an organization. A framework is disclosed which allows a user (e.g., a risk analyst) to compose analytical tools that can access data from a variety of sources (both internal and external to an enterprise) and perform a variety of analytic functions.

摘要翻译： 披露了构建和执行分析解决方案的系统，方法和制造。 这样的解决方案可以提供全面的分析解决方案（例如，风险评估，欺诈检测解决方案，动态操作风险评估，监管合规性评估等）。 分析解决方案可以使用分布在组织不同部门的各种独立创建和管理的数据存储库中的操作数据执行分析任务。 公开了允许用户（例如，风险分析员）组成可以从各种来源（企业内部和外部）访问数据并执行各种分析功能的分析工具的框架。

公开(公告)号：US20110010440A1

公开(公告)日：2011-01-13

申请号：US12813398

申请日：2010-06-10

申请人： Rajiv Kottomtharayil ,  Parag Gokhale ,  Anand Prahlad ,  Manoj Kumar ,  David Ngo ,  Varghese Devassy

发明人： Rajiv Kottomtharayil ,  Parag Gokhale ,  Anand Prahlad ,  Manoj Kumar ,  David Ngo ,  Varghese Devassy

IPC分类号： G06F13/10 ,  G06F15/173

CPC分类号： G06F3/0619 ,  G06F3/0617 ,  G06F3/0635 ,  G06F3/065 ,  G06F3/0655 ,  G06F3/067 ,  G06F3/0689 ,  G06F11/1448 ,  G06F11/1464 ,  G06F11/1469 ,  G06F17/30321 ,  G06F17/30864 ,  H04L67/1097 ,  Y10S707/99953 ,  Y10S707/99955

摘要： Methods and systems are described for performing storage operations on electronic data in a network. In response to the initiation of a storage operation and according to a first set of selection logic, a media management component is selected to manage the storage operation. In response to the initiation of a storage operation and according to a second set of selection logic, a network storage device to associate with the storage operation. The selected media management component and the selected network storage device perform the storage operation on the electronic data.

摘要翻译： 描述了用于对网络中的电子数据执行存储操作的方法和系统。 响应于开始存储操作并且根据第一组选择逻辑，选择介质管理组件来管理存储操作。 响应于开始存储操作并且根据第二组选择逻辑，与存储操作相关联的网络存储设备。 所选择的媒体管理组件和所选择的网络存储设备对电子数据执行存储操作。

公开(公告)号：US20100292201A1

公开(公告)日：2010-11-18

申请号：US12733415

申请日：2008-08-14

申请人： Tilak Raj Bhardwaj ,  Manoj Kumar ,  Neelima Dhingra ,  Neeraj Mehta

发明人： Tilak Raj Bhardwaj ,  Manoj Kumar ,  Neelima Dhingra ,  Neeraj Mehta

IPC分类号： A61K31/568 ,  C07J41/00 ,  A61P5/28 ,  A61P13/08

CPC分类号： C07J41/0016

摘要： The present invention relates to steroidal esters of 17-oximino-5-androsten-3-ol, of compound of general formula (A) wherein R is selected from a group consisting of arylalkyl, aryl, substituted aryl. The ester derivatives are synthesized starting from Dehydroandrosterone acetate. The compounds were tested for their antiproliferative activity and 5α-reductase inhibitory activity in comparison to Finasteride. Decreased androgen level have been found in serum of animal treated with newly synthesized compounds. These compounds have also shown better cytotoxicity in comparison to reference drug Finasteride. Thus such compounds can be useful in treatment of androgen dependent disorder of prostate alone or by synergistic effect they can decrease the size of prostate due to their antiproliferative activity.

摘要翻译： 本发明涉及通式（A）化合物，其中R选自芳烷基，芳基，取代芳基的17-肟基-5-雄甾-3-醇类甾体酯。 酯衍生物是从乙酸脱氢睾酮开始合成的。 与非那雄胺相比，测试了这些化合物的抗增殖活性和5α-还原酶抑制活性。 在新合成的化合物处理的动物血清中发现雄激素水平降低。 与参考药物非那雄胺相比，这些化合物也显示出更好的细胞毒性。 因此，这样的化合物可用于治疗前列腺单独的雄激素依赖性病症或通过协同作用，由于它们的抗增殖活性，它们可以减少前列腺的大小。

公开(公告)号：US20100055752A1

公开(公告)日：2010-03-04

申请号：US12374176

申请日：2007-08-03

申请人： Manoj Kumar

发明人： Manoj Kumar

IPC分类号： C12P7/06 ,  C12P19/14

CPC分类号： C12P7/06 ,  C12P19/14 ,  Y02E50/17

摘要： Described herein are starch hydrolysis processes for obtaining fermentable sugars from starch in milled plant material at temperatures below the starch gelatinization temperature and using exogenous plant alpha amylases further to the fermentation of the sugars to produce end products, such as ethanol.

摘要翻译： 本文描述的是淀粉水解方法，用于在低于淀粉糊化温度的温度下在研磨的植物材料中从淀粉获得可发酵糖，并且使用外源植物α-淀粉酶进一步进行糖的发酵以产生最终产物如乙醇。

公开(公告)号：US20090295022A1

公开(公告)日：2009-12-03

申请号：US11990658

申请日：2006-08-17

申请人： Manoj Kumar

发明人： Manoj Kumar

IPC分类号： B29D7/01 ,  C09D189/00

CPC分类号： C08K5/0016 ,  C08J3/215 ,  C08J5/10 ,  C08J2389/00 ,  C08L71/02 ,  C08L89/00 ,  Y10T428/249921 ,  C08L2666/22

摘要： A composite of one or more repeat sequence protein polymers and either one or more metal oxides or one or more plasticizers alters material properties of the repeat sequence protein polymers, including the morphology of the polymers as well as the elastic modulus and tensile strength. The morphology of the composite is aligned, generally parallel nanofibers.

摘要翻译： 一种或多种重复序列蛋白质聚合物和一种或多种金属氧化物或一种或多种增塑剂的复合物改变重复序列蛋白质聚合物的材料性质，包括聚合物的形态以及弹性模量和拉伸强度。 将复合材料的形态对准，一般平行的纳米纤维。

公开(公告)号：US20090220938A1

公开(公告)日：2009-09-03

申请号：US11911325

申请日：2006-04-13

申请人： Manoj Kumar ,  Sang-Kyu Lee

发明人： Manoj Kumar ,  Sang-Kyu Lee

IPC分类号： C12Q1/70 ,  C12M1/00

CPC分类号： G01N33/56983 ,  B01L3/5023 ,  B01L2300/027 ,  B01L2300/0636 ,  B01L2300/0825 ,  C12Q1/6825 ,  G01N33/54373 ,  G01N33/554 ,  G01N2333/11

摘要： The present invention provides a method of detecting viruses, such as respiratory-related viruses, in a sample with a sensitivity of at least 80%, and/or specificity of at least 90%, and/or with an accuracy of at least 90%. The method comprises contacting the sample with a biosensor. The present invention also provides a biosensor comprising a membrane and a solid conducting surface, with the membrane being attached to the solid conducting surface in a manner such that a reservoir exists therebetween. The membrane comprises first and second layers each comprising closely packed amphiphilic molecules; a plurality of first and second ionophores located in the first and second layers, respectively; and a plurality of antibodies or fragments thereof directed against nucleoproteins of respiratory-related viruses, more specifically, nucleoproteins of an influenza virus, and covalently attached to the second ionophores. The present invention further provides a device comprising an array of such biosensors.

摘要翻译： 本发明提供了一种在灵敏度至少为80％，和/或至少90％的特异性和/或精确至少为90％的样品中检测病毒如呼吸道相关病毒的方法， 。 该方法包括使样品与生物传感器接触。 本发明还提供了一种生物传感器，其包括膜和固体导电表面，其中膜以这样的方式附着到固体导电表面上。 膜包括第一层和第二层，每层包含紧密堆积的两亲分子; 分别位于第一和第二层中的多个第一和第二离子载体; 多个抗体或其片段针对呼吸相关病毒的核蛋白，更具体地针对流感病毒的核蛋白，并且共价连接到第二离子载体上。 本发明还提供一种包括这种生物传感器的阵列的装置。

公开(公告)号：US07229795B2

公开(公告)日：2007-06-12

申请号：US10787267

申请日：2004-02-25

申请人： Veronique A. Dartois ,  James A. Hoch ,  Fernando Valle ,  Manoj Kumar

发明人： Veronique A. Dartois ,  James A. Hoch ,  Fernando Valle ,  Manoj Kumar

IPC分类号： C12P19/00 ,  C12N1/20

CPC分类号： C07K14/26

摘要： The invention provides isolated nucleic acid molecules encoding polypeptides having 2,5-DKG permease activity, and oligonucleotides therefrom. The isolated nucleic acid molecules can be expressed in appropriate bacterial cells to enhance the production of 2-KLG, which can subsequently be converted to ascorbic acid. Further provided are isolated polypeptides having 2,5-DKG permease activity, immunogenic peptides therefrom, and antibodies specific therefor. The invention also provides methods of identifying novel 2,5-DKG permeases.

摘要翻译： 本发明提供了编码具有2,5-DKG通透酶活性的多肽的分离的核酸分子及其寡核苷酸。 分离的核酸分子可以在适当的细菌细胞中表达以增强2-KLG的产生，随后将其转化为抗坏血酸。 还提供了具有2,5-DKG通透酶活性的分离的多肽，其免疫原性肽及其特异的抗体。 本发明还提供鉴定新型2,5-DKG通透酶的方法。