公开(公告)号：US5834212A

公开(公告)日：1998-11-10

申请号：US417847

申请日：1995-04-06

申请人： Yasunori Okada ,  Masayoshi Shinmei ,  Taro Hayakawa ,  Kazushi Iwata ,  Yumi Korin ,  Shuji Kodama ,  Shinichi Yoshida

发明人： Yasunori Okada ,  Masayoshi Shinmei ,  Taro Hayakawa ,  Kazushi Iwata ,  Yumi Korin ,  Shuji Kodama ,  Shinichi Yoshida

IPC分类号： C12N5/10 ,  C07K16/00 ,  C07K16/40 ,  C07K19/00 ,  C12N5/20 ,  C12N9/64 ,  C12N15/02 ,  C12P21/08 ,  C12R1/91 ,  G01N33/564 ,  G01N33/573 ,  G01N33/577 ,  G01N33/543

CPC分类号： C12N9/6491 ,  C07K16/40

摘要： Anti-human stromelysin monoclonal antibodies reactive with latent and active forms of stromelysin without discrimination between the two, each being immunoreactive with only one of the antigenic determinants of human stromelysin, are provided. The use of a combination of two such monoclonal antibodies which specifically react with different antigenic determinants of human stromelysin renders it possible to accurately determine the amount of human stromelysin in human body fluids, and thus to carry out the diagnosis of rheumatoid arthritis. There are thus provided said monoclonal antibodies per se, a sandwich enzyme immunoassay for the determination of the amount of human stromelysin in human body fluid samples using a combination of two such monoclonal antibodies, and a method for the diagnosis of rheumatoid arthritis using said immunoassay.

摘要翻译： 与人类基质溶素的一个抗原决定簇之间的免疫反应性提供了两者之间的区别两者的潜在和活性形式的基质溶素的抗人基质溶素蛋白单克隆抗体。 使用与人类溶基质蛋白酶的不同抗原决定簇特异性反应的两种这样的单克隆抗体的组合使得可以准确地确定人体液中的人类基质溶素的量，从而进行类风湿性关节炎的诊断。 因此，提供了所述单克隆抗体本身，使用两种这样的单克隆抗体的组合来测定人体液样品中人基质溶素的量的夹心酶免疫测定法和使用所述免疫测定法诊断类风湿性关节炎的方法。

公开(公告)号：US5696920A

公开(公告)日：1997-12-09

申请号：US789691

申请日：1997-01-27

申请人： Souichi Miyata ,  Shinichi Yoshida ,  Tsuyoshi Muramatsu

发明人： Souichi Miyata ,  Shinichi Yoshida ,  Tsuyoshi Muramatsu

IPC分类号： G06F9/44 ,  G06F9/445 ,  G06F15/82

CPC分类号： G06F9/4436 ,  G06F9/445

摘要： A data driven type information processor includes a data driven type information processing unit, and a download unit. The information processing unit includes a program storing unit and an input/output control unit of a data packet for storing information stored in a data packet including a load instruction into the program storing unit and for carrying out a data driven type process on data packets including other instructions according to information stored in the program storing unit. The download unit downloads program data to the information processing unit by applying a data packet including the load instruction and program data to be stored in the program storing unit. The download unit includes a memory for storing program data, a readout circuit for reading out a set of program data stored in the memory, and a packet generation circuit for generating a data packet including the load instruction and readout program data to provide the same to the input/output control unit of the information processing unit. The memory may store a plurality of sets of program data.

摘要翻译： 数据驱动型信息处理器包括数据驱动型信息处理单元和下载单元。 信息处理单元包括程序存储单元和数据分组的输入/输出控制单元，用于存储存储在包括程序存储单元的加载指令的数据分组中的信息，并且对数据分组执行数据驱动类型处理，包括 根据存储在程序存储单元中的信息的其他指令。 下载单元通过应用包含要存储在程序存储单元中的加载指令和程序数据的数据分组将程序数据下载到信息处理单元。 下载单元包括用于存储程序数据的存储器，用于读出存储在存储器中的一组程序数据的读出电路，以及用于产生包括加载指令和读出程序数据的数据分组的分组生成电路，以将其提供给 信息处理单元的输入/输出控制单元。 存储器可以存储多组节目数据。

公开(公告)号：US5631396A

公开(公告)日：1997-05-20

申请号：US647164

申请日：1996-05-09

申请人： Keigo Nishihira ,  Shinichi Yoshida ,  Shuji Tanaka ,  Yutaka Asada

发明人： Keigo Nishihira ,  Shinichi Yoshida ,  Shuji Tanaka ,  Yutaka Asada

IPC分类号： B01J27/13 ,  C07B61/00 ,  C07C68/00 ,  C07C68/08 ,  C07C69/96

CPC分类号： C07C68/00

摘要： Dimethyl carbonate ((CH.sub.3 O).sub.2 CO) is continuously produced by a catalytic reaction (first step) of CO with CH.sub.3 NO.sub.2, with a significantly reduced loss of CH.sub.3 ONO by the process including a second step wherein (CH.sub.3 O).sub.2 CO in a reaction product gas of the first step is absorbed by dimethyl oxalate while contacting the resultant liquid fraction with CO to recover CH.sub.3 ONO, a third step wherein CH.sub.3 ONO is regenerated from NO in the condensed gas fraction produced in the second step and molecular oxygen and CH.sub.3 OH introduced into the third step, the resultant regenerated gas fraction being recycled and reused as a feed gas for the first step, and a fourth step wherein (CH.sub.3 O).sub.2 CO contained in the liquid fraction of the second step is collected.

摘要翻译： 通过CO与CH3NO2的催化反应（第一步）连续制备碳酸二甲酯（（CH 3 O）2 CO），通过包括第二步骤的CH 3 NOO的显着降低的损失，其中（CH 3 O）2 CO在反应产物气体中的 第一步被草酸二甲酯吸收，同时使所得液体馏分与CO接触以回收CH 3 NOO，第三步是在第二步产生的冷凝气体馏分中从NO再生CH3ONO，并将第三步中引入分子氧和CH3OH， 所产生的再生气体馏分被再循环并重新用作第一步骤的进料气体;以及第四步骤，其中收集第二步骤的液体馏分中所含的（CH 3 O）2 CO。

公开(公告)号：US5535413A

公开(公告)日：1996-07-09

申请号：US533860

申请日：1995-09-26

申请人： Yutaka Ishikawa ,  Shinichi Yoshida

发明人： Yutaka Ishikawa ,  Shinichi Yoshida

IPC分类号： G06F15/82 ,  G06F15/173 ,  G06F15/62

CPC分类号： G06F15/17381

摘要： The system includes data driven processors each having inputs and outputs. Each processor includes a processing unit processing, according to a program, a data packet having processor specifying information specifying the processor, and an output unit providing a data packet having processor specifying information specifying another processor according to a predetermined condition. The system further includes an input path selecting device and a transmission path device. The input path selecting device has inputs respectively connected to the system inputs, and outputs. The input path selecting device selects an output of the input path selecting device according to the contents of the received data packet and a predetermined condition to provide the data packet therefrom. The transmission path connects the outputs of the input path selecting device and the system outputs, and the inputs/outputs of the data driven processors to each other. The system may further include an output path selecting device. The output path selecting device is provided between the outputs of the processors in the transmission path device and the system outputs and has a plurality of inputs respectively connected to the outputs of the processors and a plurality of outputs respectively connected to the system outputs. The output path selecting device selects an output depending on the processor specifying information of a received data packet and provides the data packet therefrom.

摘要翻译： 该系统包括每个具有输入和输出的数据驱动处理器。 每个处理器包括处理单元，根据程序处理具有指定处理器的处理器指定信息的数据分组，以及根据预定条件提供具有指定另一处理器的处理器指定信息的数据分组的输出单元。 该系统还包括输入路径选择装置和传输路径装置。 输入路径选择装置具有分别连接到系统输入的输入并输出。 输入路径选择装置根据接收到的数据包的内容和预定条件选择输入路径选择装置的输出，以从其提供数据包。 传输路径将输入路径选择装置的输出和系统输出以及数据驱动处理器的输入/输出彼此连接。 该系统还可以包括输出路径选择装置。 输出路径选择装置设置在传输路径装置中的处理器的输出和系统输出之间，并且具有分别连接到处理器的输出的多个输入端和分别连接到系统输出的多个输出。 输出路径选择装置根据接收到的数据包的处理器指定信息选择输出，并从其提供数据包。

公开(公告)号：US5502834A

公开(公告)日：1996-03-26

申请号：US215564

申请日：1994-03-22

申请人： Katsumi Arata ,  Shinichi Yoshida ,  Tsuyoshi Muramatsu

发明人： Katsumi Arata ,  Shinichi Yoshida ,  Tsuyoshi Muramatsu

IPC分类号： G06F12/00 ,  G06F15/82 ,  G09G5/393 ,  G06F13/12

CPC分类号： G09G5/393

摘要： A memory interface apparatus includes: a pipeline register holding a data packet from a transmission path to provide an instruction code, a generation number, and data separately; a memory access unit accessing an image memory according to the instruction code, a circuit latching the output of the image memory; an ALU carrying out an operation specified by the instruction code from the pipeline register between data from the pipeline register and the output of the latch circuit for output of the operation result; a selector responsive to a select signal for selecting one of data from the pipeline register and the output of the ALU to apply the selected result to the image memory as data; an output unit generating a data packet including a result of a series of complex operation carried out by the pipeline register, the image memory, and the ALU for output; a transmission control unit controlling transmission of a data packet on the transmission path carried out by the pipeline register and the output unit; and a control unit responsive to the instruction code from the pipeline register for controlling the ALU, the memory access unit, the image memory, the latch circuit, the selector, the output unit, and the transmission control unit so that a series of complex operation processing including an access to the image memory specified by the instruction code is carried out.

摘要翻译： 存储器接口装置包括：流水线寄存器，其保存来自传输路径的数据分组以分别提供指令代码，生成号和数据; 存储器访问单元，根据指令代码访问图像存储器;锁存图像存储器的输出的电路; ALU在来自流水线寄存器的数据和锁存电路的输出之间从流水线寄存器指定的指令执行操作，以输出操作结果; 响应于选择信号的选择器，用于从流水线寄存器选择数据中的一个和ALU的输出，以将所选择的结果作为数据应用于图像存储器; 产生包括由流水线寄存器，图像存储器和ALU执行的一系列复杂操作的结果的数据分组的输出单元，用于输出; 传输控制单元，控制由流水线寄存器和输出单元执行的传输路径上的数据分组的传输; 以及控制单元，其响应来自流水线寄存器的指令代码来控制ALU，存储器存取单元，图像存储器，锁存电路，选择器，输出单元和传输控制单元，使得一系列复杂操作 执行包括对由指令代码指定的图像存储器的访问的处理。

公开(公告)号：US5428812A

公开(公告)日：1995-06-27

申请号：US265621

申请日：1994-06-24

申请人： Shinichi Yoshida

发明人： Shinichi Yoshida

IPC分类号： G06F15/16 ,  G06F9/44 ,  G06F15/163 ,  G06F15/82 ,  G06F15/76

CPC分类号： G06F9/4436

摘要： A destination field of a data packet to be processed by a data driven type processor includes a field for storing a processor number for specifying a processor by which the data packet is to be processed and a field for storing a node number for addressing a memory space wherein a data flow program to be executed us stored. In a case of structuring one system by coupling a plurality of such data driven type processors, a minimum bit width of the above-described processor number field is determined according to the number of data driven type processors and all fields but the processor number field of the destination field are allotted to the above-described node number field. As a result, the node number field is always allotted a maximum bit width according to the number of data driven type processors constituting the system, so that a memory space allowing the above-described addressing is constantly made largest, in other words, an executable program capacity in each data driven type processor and the system is always maintained at a maximum.

摘要翻译： 要由数据驱动型处理器处理的数据包的目的地字段包括用于存储用于指定要处理数据包的处理器的处理器号的字段和用于存储用于寻址存储器空间的节点号的字段 其中存储要执行的数据流程序。 在通过耦合多个这种数据驱动型处理器来构造一个系统的情况下，根据数据驱动类型处理器的数量和所有字段而确定上述处理器号字段的最小位宽，但是处理器号字段 将目的地字段分配给上述节点号字段。 结果，根据构成系统的数据驱动型处理器的数量，总是分配最大位宽，使得允许上述寻址的存储器空间不断变大，换句话说，可执行 每个数据驱动型处理器和系统中的程序容量始终保持在最大值。

公开(公告)号：US5392405A

公开(公告)日：1995-02-21

申请号：US208032

申请日：1994-03-09

申请人： Koji Komatsu ,  Shinichi Yoshida ,  Souichi Miyata ,  Daisuke Azuma

发明人： Koji Komatsu ,  Shinichi Yoshida ,  Souichi Miyata ,  Daisuke Azuma

IPC分类号： G06F7/02 ,  G06F9/44 ,  G06F13/38 ,  G06F13/14

CPC分类号： G06F9/4436 ,  G06F7/02

摘要： So-called template matching processing is function-distributed into a pre-detecting portion and a template matching portion, processing in the respective portions being achieved by a hardware circuit. In the pre-detecting portion, the relationship between data which simultaneously exist in the determined comparing sections on data transmission paths, and matching processing is performed in advance with respect to data to be matched. The template matching portion includes an addressing type general-purpose memory and performs main processing of template matching based on the result of the comparison and determination in the pre-detecting portion.

摘要翻译： 所谓的模板匹配处理功能分布到预检测部分和模板匹配部分中，各部分的处理由硬件电路实现。 在预检测部分中，相对于要匹配的数据，预先执行在确定的数据传输路径上的比较部分中同时存在的数据与匹配处理之间的关系。 模板匹配部分包括寻址型通用存储器，并且基于预检测部分中的比较和确定的结果执行模板匹配的主要处理。

公开(公告)号：US5038348A

公开(公告)日：1991-08-06

申请号：US374060

申请日：1989-06-30

申请人： Kazuhiko Yoda ,  Toshiya Okamoto ,  Shinichi Yoshida

发明人： Kazuhiko Yoda ,  Toshiya Okamoto ,  Shinichi Yoshida

IPC分类号： G06F11/36

CPC分类号： G06F11/3664 ,  G06F11/3604

摘要： An apparatus for debugging a data flow program simulates functions corresponding to a plurality of structural portions of a processing apparatus in accordance with a data flow program stored in a program file. The state of execution corresponding to respective lines of a source program of the executed plurality of functional portions are stored in a PS file and the processes in respective functional portions and the states of execution employed for the execution of the source program are stored in a data packet file. A debug information file (22) stores the debug information indicative of the corresponding relation between the respective lines of the source program and respective nodes of the data flow program. A display displays debug information in association with respective lines of the source program in accordance with the execution of respective nodes of the data flow program.

摘要翻译： 用于调试数据流程序的装置根据存储在程序文件中的数据流程序来模拟与处理装置的多个结构部分相对应的功能。 与执行的多个功能部分的源程序的各行相对应的执行状态存储在PS文件中，并且将用于执行源程序的各个功能部分和执行状态中的处理存储在数据中 包文件。 调试信息文件（22）存储指示源程序的各行与数据流程序的各个节点之间的对应关系的调试信息。 根据数据流程序的相应节点的执行，显示器显示与源程序的各行相关联的调试信息。

公开(公告)号：US4904822A

公开(公告)日：1990-02-27

申请号：US307948

申请日：1989-02-09

申请人： Hiroyuki Nohira ,  Shinichi Yoshida

发明人： Hiroyuki Nohira ,  Shinichi Yoshida

IPC分类号： C07C51/487

CPC分类号： C07C51/487

摘要： A process for the optical resolution of (.+-.)-2-hydroxy-4-phenylbutanoic acid which comprises treating (.+-.)-2-hydroxy-4-phenylbutanoic acid with an optically active 1-(p-tolyl)ethylamine or an optically active N-(2-hydroxy)ethyl-.alpha.-methylbenzylamine as a resolving agent is provided by the present invention.According to the invention, (-)-2-hydroxy-4-phenylbutanoic acid, which is useful as a starting substance for the synthesis of angiotensin converting enzyme-inhibiting pharmaceuticals, can especially be obtained in a highly pure state and in a high yield.

公开(公告)号：US4613425A

公开(公告)日：1986-09-23

申请号：US572097

申请日：1984-01-19

申请人： Hidehiro Higashi ,  Katsuhiro Shirono ,  Yuusaku Arima ,  Yoichi Nishimura ,  Shinichi Yoshida

发明人： Hidehiro Higashi ,  Katsuhiro Shirono ,  Yuusaku Arima ,  Yoichi Nishimura ,  Shinichi Yoshida

IPC分类号： C10G45/04 ,  B01J23/84 ,  B01J23/847 ,  B01J23/85 ,  B01J35/02 ,  B01J35/10 ,  C10G45/08 ,  C10G65/04

CPC分类号： C10G45/08 ,  B01J35/002 ,  B01J35/0073 ,  B01J35/023 ,  B01J35/026 ,  B01J35/108 ,  C10G65/04

摘要： A two-stage process for hydrotreating asphaltenes and metallic contaminants-containing heavy hydrocarbon oils which comprises a demetallization step using a catalyst composition which is smaller in pore size and less in active metal amount than the conventional demetallization catalysts, and a hydrotreating step using a catalyst composition which is larger in pore size and more in active metal amount than the conventional hydrodesulfurization catalysts or hydrocracking catalysts, said hydrotreating step being located downstream of said demetallization step.

摘要翻译： 一种用于加氢处理沥青质和含金属污染物的重质烃油的两阶段方法，其包括使用催化剂组合物的脱金属步骤，所述催化剂组合物的孔径小于活性金属量小于常规脱金属催化剂的催化剂组合物，以及使用催化剂的加氢处理步骤 组成比现有的加氢脱硫催化剂或加氢裂化催化剂的孔径大，活性金属量多，所述加氢处理步骤位于所述脱金属化步骤的下游。