摘要:
A process for preparing an azetidinone derivative represented by the formula ##STR1## wherein R.sup.1 is hydrogen, halogen or lower alkoxy, R.sup.2 is hydrogen, halogen, lower alkoxy, amino or a group ##STR2## (in which R.sup.5 is substituted or unsubstituted phenyl, substituted or unsubstituted phenylmethyl, substituted or unsubstituted phenoxymethyl, or substituted or unsubstituted benzoyl), or R.sup.1 and R.sup.2, when taken together, are carbonyl, R.sup.3 is substituted or unsubstituted phenyl, and R.sup.4 is hydrogen, optionally substituted hydrocarbon residue or acyl, silyl, sulfonyl or phosphonyl derived from inorganic acid or organic acid, the process comprising reacting a dithioazetidinone derivative represented by the formula ##STR3## wherein R.sup.1, R.sup.2 and R.sup.4 are as defined above and R.sup.9 is substituted or unsubstituted, nitrogen-containing aromatic heterocyclic residue with a compound represented by the formulaR.sup.3 SO.sub.2 CN (VII)wherein R.sup.3 is defined above.
摘要:
A process for preparing an azetidinone derivative represented by the formula (1) ##STR1## wherein R.sup.1 represents a substituted or unsubstituted aryl group, a substituted or unsubstituted phenylmethyl group or a substituted or unsubstituted phenoxymethyl group, R.sup.2 represents a hydrogen atom or a group for protecting carboxylic acid and Ar represents a substituted or unsubstituted phenyl group, the process comprising reacting a thiazolineazetidinone derivative represented by the formula (2) ##STR2## wherein R.sup.1 and R.sup.2 are as defined above with a sulfonyl bromide represented by the formula (3)Ar--SO.sub.2 --Br (3)wherein Ar is as defined above in water-containing organic solvent.
摘要:
This invention provides a process for preparing a 3-exo-methylenecepham derivative represented by the formula ##STR1## wherein R.sup.1 represents an aralkyl or aryloxymethyl group both of which may be substituted on the aromatic ring, and R.sup.2 represents a carboxyl-protecting group, the process comprising subjecting a compound represented by the formula ##STR2## wherein R.sup.1 and R.sup.2 are as defined above, to a cyclization reaction in an acidic water-containing solvent.
摘要:
This invention provides thiazolinoazetidinone derivatives represented by the formula ##STR1## and processes for preparing the same. The thiazolinoazetidinone derivatives are used as the intermediates for producing cephalosporin compounds useful as antibiotic agents.
摘要:
This invention provides a process for preparing 2-oxycephalosporin derivative represented by the formula ##STR1## wherein R.sup.1 represents hydrogen atom, acyl group, or lower alkoxycarbonyl group optionally substituted with halogen atom, R.sup.2 represents hydrogen atom, halogen atom or acyloxy group optionally substituted with halogen atom, R.sup.3 represents hydrogen atom, lower alkyl group optionally substituted with halogen atom, or phenyl-lower alkyl group which may be optionally substituted with nitro group, halogen atom or lower alkoxy group on the phenyl ring, and R.sup.4 represents lower primary or secondary alkyl or lower alkylcarbonyl, the process comprising electrolytically oxidizing a cephalosporin derivative represented by the formula ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above, in the presence of a lower carboxylic acid or lower primary or secondary alcohol, and a supporting electrolyte.
摘要:
This invention provides a process for preparing a thiazolinoazetidinone derivative represented by the formula ##STR1## wherein R.sup.1 represents aralkyl group or aryloxymethyl group and R.sup.2 represents acyl group, the process comprising electrolyzing a compound of the formula ##STR2## wherein R.sup.1 is as defined above in the presence of a lower fatty acid.
摘要:
2-Substituted-cyclopentanone derivatives represented by the formula ##STR1## are prepared by subjecting a 2-benzothiazolylsulfenamide derivative represented by the formula ##STR2## and cyclopentanone to condensation reaction, or by reacting the resulting condensation product with a hydrocarbon halide represented by the formulaR.sub.1 X.
摘要:
An image-reading unit includes an original document conveyor that includes a first original document tray to hold an original document to be read, a first original document feeding port to feed the original document placed on the first original document tray, and an original document conveying path to convey the original document from the first original document feeding port to an original document discharging port. The original document conveyor further includes an openable second original document tray attached near an intermediate portion of the original document conveying path to hold an original document when opened, and a second original document feeding port to feed the original document on the second original document tray. The image-reading unit further includes an image reader to read an image of the original document being conveyed along the original document conveying path.
摘要:
Disclosed is a process for producing a phosphine derivative from a phosphine oxide derivative, which comprises the following steps: (I) mixing a phosphine oxide derivative represented by formula (1) with a chlorinating agent in a polar organic solvent to cause the reaction between these components; and (II-1) adding a salt of a metal having an ionization tendency equal to or lower than that of aluminum to the reaction mixture and carrying out the reductive reaction in the presence of aluminum or (II-2) subjecting the reaction mixture to electrolytic reduction, thereby producing a phosphine derivative represented by formula (2). ArnR3-nP═O (1) ArnR3-nP (2) In formulae (1) and (2), Ar represents an aryl group such as a phenyl group, a phenyl group having a substituent, a heteroaromatic ring group, and a heteroaromatic ring group having a substituent; R represents an aliphatic hydrocarbon group or an aliphatic hydrocarbon group having a substituent; and n represents an integer of 0 to 3.
摘要:
Disclosed is technology for holding a substrate and, specifically, an object holding apparatus including a chuck for holding an object, a holding unit for holding the chuck, a generating unit provided in the holding unit, for generating a field related to an attraction force, a member provided in the chuck and attracted by the generating unit in accordance with the field, and a supporting unit for supporting one of the generating unit and the member, for movement at least in a direction nearing the other and in a direction away from the other.