Process for preparation of azetidinone derivatives
    51.
    发明授权
    Process for preparation of azetidinone derivatives 失效
    氮杂环丁酮衍生物的制备方法

    公开(公告)号:US4713452A

    公开(公告)日:1987-12-15

    申请号:US680723

    申请日:1984-12-12

    CPC分类号: C07D205/09 C07D205/095

    摘要: A process for preparing an azetidinone derivative represented by the formula ##STR1## wherein R.sup.1 is hydrogen, halogen or lower alkoxy, R.sup.2 is hydrogen, halogen, lower alkoxy, amino or a group ##STR2## (in which R.sup.5 is substituted or unsubstituted phenyl, substituted or unsubstituted phenylmethyl, substituted or unsubstituted phenoxymethyl, or substituted or unsubstituted benzoyl), or R.sup.1 and R.sup.2, when taken together, are carbonyl, R.sup.3 is substituted or unsubstituted phenyl, and R.sup.4 is hydrogen, optionally substituted hydrocarbon residue or acyl, silyl, sulfonyl or phosphonyl derived from inorganic acid or organic acid, the process comprising reacting a dithioazetidinone derivative represented by the formula ##STR3## wherein R.sup.1, R.sup.2 and R.sup.4 are as defined above and R.sup.9 is substituted or unsubstituted, nitrogen-containing aromatic heterocyclic residue with a compound represented by the formulaR.sup.3 SO.sub.2 CN (VII)wherein R.sup.3 is defined above.

    摘要翻译: 制备式(I)表示的氮杂环丁酮衍生物的方法,其中R 1是氢,卤素或低级烷氧基,R 2是氢,卤素,低级烷氧基,氨基或基团(其中R 5是取代的或 未取代的苯基,取代或未取代的苯基甲基,取代或未取代的苯氧基甲基或取代或未取代的苯甲酰基),或R 1和R 2一起为羰基,R 3为取代或未取代的苯基,且R 4为氢,任选取代的烃残基或酰基 ,衍生自无机酸或有机酸的甲硅烷基,磺酰基或膦酰基,该方法包括使由式(VI)表示的二硫代氮杂环丁酮衍生物(其中R 1,R 2和R 4如上所定义)和R 9是取代或未取代的, 含有由式R 3 SO 2 CN(Ⅶ)表示的化合物的芳族杂环残基,其中R 3如上定义。

    Process for preparing azetidinone derivatives
    52.
    发明授权
    Process for preparing azetidinone derivatives 失效
    制备氮杂环丁酮衍生物的方法

    公开(公告)号:US4566996A

    公开(公告)日:1986-01-28

    申请号:US567736

    申请日:1984-01-03

    CPC分类号: C07D205/095 Y02P20/55

    摘要: A process for preparing an azetidinone derivative represented by the formula (1) ##STR1## wherein R.sup.1 represents a substituted or unsubstituted aryl group, a substituted or unsubstituted phenylmethyl group or a substituted or unsubstituted phenoxymethyl group, R.sup.2 represents a hydrogen atom or a group for protecting carboxylic acid and Ar represents a substituted or unsubstituted phenyl group, the process comprising reacting a thiazolineazetidinone derivative represented by the formula (2) ##STR2## wherein R.sup.1 and R.sup.2 are as defined above with a sulfonyl bromide represented by the formula (3)Ar--SO.sub.2 --Br (3)wherein Ar is as defined above in water-containing organic solvent.

    摘要翻译: 制备由式(1)表示的氮杂环丁酮衍生物的方法其中R1表示取代或未取代的芳基,取代或未取代的苯基甲基或取代或未取代的苯氧基甲基,R2表示氢原子或 用于保护羧酸和Ar的基团代表取代或未取代的苯基,该方法包括使式(2)表示的噻唑啉氮杂环丁酮衍生物(2)其中R1和R2如上定义, 式(3)Ar-SO 2-Br(3)其中Ar如上所述在含水有机溶剂中。

    Process for preparing 2-oxycephalosporin derivatives
    55.
    发明授权
    Process for preparing 2-oxycephalosporin derivatives 失效
    2-羟基头孢菌素衍生物的制备方法

    公开(公告)号:US4401528A

    公开(公告)日:1983-08-30

    申请号:US407328

    申请日:1982-08-12

    CPC分类号: C07D501/04

    摘要: This invention provides a process for preparing 2-oxycephalosporin derivative represented by the formula ##STR1## wherein R.sup.1 represents hydrogen atom, acyl group, or lower alkoxycarbonyl group optionally substituted with halogen atom, R.sup.2 represents hydrogen atom, halogen atom or acyloxy group optionally substituted with halogen atom, R.sup.3 represents hydrogen atom, lower alkyl group optionally substituted with halogen atom, or phenyl-lower alkyl group which may be optionally substituted with nitro group, halogen atom or lower alkoxy group on the phenyl ring, and R.sup.4 represents lower primary or secondary alkyl or lower alkylcarbonyl, the process comprising electrolytically oxidizing a cephalosporin derivative represented by the formula ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above, in the presence of a lower carboxylic acid or lower primary or secondary alcohol, and a supporting electrolyte.

    摘要翻译: 本发明提供一种制备由式(I)表示的2-羟基头孢菌素衍生物的方法,其中R 1表示氢原子,酰基或任选被卤素原子取代的低级烷氧基羰基,R 2表示氢原子,卤素原子或酰氧基 任选被卤素原子取代,R 3表示氢原子,任选被卤素原子取代的低级烷基或苯基 - 可以任意被硝基,卤素原子或苯环上的低级烷氧基取代的苯基 - 低级烷基,R4表示低级 伯或仲烷基或低级烷基羰基,该方法包括在低级羧酸或较低级初级或次级级存在下电解氧化式(II)表示的头孢菌素衍生物,其中R 1,R 2和R 3如上定义。 酒精和支持电解质。

    Cyclopentanone intermediates 2-(benzothiazolyl-2)
    57.
    发明授权
    Cyclopentanone intermediates 2-(benzothiazolyl-2) 失效
    环戊酮中间体2-(苯并噻唑基-2)

    公开(公告)号:US4238615A

    公开(公告)日:1980-12-09

    申请号:US884222

    申请日:1978-03-07

    CPC分类号: C07D277/74 C07C45/673

    摘要: 2-Substituted-cyclopentanone derivatives represented by the formula ##STR1## are prepared by subjecting a 2-benzothiazolylsulfenamide derivative represented by the formula ##STR2## and cyclopentanone to condensation reaction, or by reacting the resulting condensation product with a hydrocarbon halide represented by the formulaR.sub.1 X.

    摘要翻译: 由式“IMAGE”表示的2-取代的环戊酮衍生物是通过使由式< IMAGE>表示的2-苯并噻唑基亚磺酰胺衍生物和环戊酮进行缩合反应,或通过使所得缩合产物与由式 R1X。

    Process for production of phosphine derivative from phosphine oxide derivative
    59.
    发明授权
    Process for production of phosphine derivative from phosphine oxide derivative 失效
    由氧化膦衍生物制备膦衍生物的方法

    公开(公告)号:US08426629B2

    公开(公告)日:2013-04-23

    申请号:US12991931

    申请日:2009-05-14

    IPC分类号: C07F9/28

    摘要: Disclosed is a process for producing a phosphine derivative from a phosphine oxide derivative, which comprises the following steps: (I) mixing a phosphine oxide derivative represented by formula (1) with a chlorinating agent in a polar organic solvent to cause the reaction between these components; and (II-1) adding a salt of a metal having an ionization tendency equal to or lower than that of aluminum to the reaction mixture and carrying out the reductive reaction in the presence of aluminum or (II-2) subjecting the reaction mixture to electrolytic reduction, thereby producing a phosphine derivative represented by formula (2). ArnR3-nP═O (1) ArnR3-nP (2) In formulae (1) and (2), Ar represents an aryl group such as a phenyl group, a phenyl group having a substituent, a heteroaromatic ring group, and a heteroaromatic ring group having a substituent; R represents an aliphatic hydrocarbon group or an aliphatic hydrocarbon group having a substituent; and n represents an integer of 0 to 3.

    摘要翻译: 公开了一种由氧化膦衍生物制备膦衍生物的方法,其包括以下步骤:(I)将式(1)表示的氧化膦衍生物与氯化剂在极性有机溶剂中混合,引起它们之间的反应 组件; 和(II-1)将具有等于或低于铝的电离倾向的金属的盐加入到反应混合物中并在铝的存在下进行还原反应或(II-2)使反应混合物 电解还原,从而制得由式(2)表示的膦衍生物。 ArnR3-nP = O(1)ArnR3-nP(2)在式(1)和(2)中,Ar表示芳基,例如苯基,具有取代基的苯基,杂芳族环基和杂芳族 具有取代基的环基; R表示脂肪族烃基或具有取代基的脂族烃基; n表示0〜3的整数。

    Substrate holding technique
    60.
    发明授权
    Substrate holding technique 失效
    基材保持技术

    公开(公告)号:US07999919B2

    公开(公告)日:2011-08-16

    申请号:US11675868

    申请日:2007-02-16

    IPC分类号: G03B27/62 G03B27/58 H01F7/20

    摘要: Disclosed is technology for holding a substrate and, specifically, an object holding apparatus including a chuck for holding an object, a holding unit for holding the chuck, a generating unit provided in the holding unit, for generating a field related to an attraction force, a member provided in the chuck and attracted by the generating unit in accordance with the field, and a supporting unit for supporting one of the generating unit and the member, for movement at least in a direction nearing the other and in a direction away from the other.

    摘要翻译: 公开了用于保持基板的技术,具体地,包括用于保持物体的夹头的物体保持装置,用于保持卡盘的保持单元,设置在保持单元中的用于产生与吸引力有关的场的发生单元, 设置在卡盘中并被根据现场被发电单元吸引的构件,以及用于支撑发电单元和构件中的一个的支撑单元,用于至少沿着接近另一方的方向并且沿远离 其他。