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公开(公告)号:US20110042565A1
公开(公告)日:2011-02-24
申请号:US12917720
申请日:2010-11-02
Applicant: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
Inventor: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
IPC: H01J49/40
CPC classification number: G01N27/622 , H01J49/0027 , H01J49/0031 , H01J49/004 , H01J49/0045 , H01J49/02 , H01J49/062 , H01J49/065 , H01J49/066 , H01J49/40 , H01J49/401 , H01J49/42
Abstract: A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator 4 and an ion guide 6 arranged downstream of the ion mobility spectrometer or separator 4. A plurality of axial potential wells are created in the ion guide 6 so that ions received from the ion mobility spectrometer or separator 4 become confined in separate axial potential wells. The potential wells maintain the fidelity and/or composition of ions received from the ion mobility spectrometer or separator 4. The potential wells are translated along the length of the ion guide 6.
Abstract translation: 公开了一种质谱仪,其包括离子迁移谱仪或分离器4和布置在离子迁移谱仪或分离器4下游的离子导向器6.在离子导向器6中产生多个轴向势阱,使得从离子迁移率 光谱仪或分离器4被限制在单独的轴向势阱中。 势阱保持从离子迁移谱仪或分离器4接收的离子的保真度和/或组成。势阱沿离子导向器6的长度平移。
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公开(公告)号:US20110024616A1
公开(公告)日:2011-02-03
申请号:US12745265
申请日:2008-12-01
Applicant: Steven Derek Pringle
Inventor: Steven Derek Pringle
IPC: H01J49/02
CPC classification number: H01J49/025 , H01J47/02
Abstract: A mass spectrometer is disclosed comprising a Gas Electron Multiplier ion detector. The ion detector comprises three gas electron multiplier stages GEM1, GEM2, GEM3 wherein a counter electrode (12) is arranged adjacent the first electron multiplier stage GEM1.
Abstract translation: 公开了一种质谱仪,其包括气体电子倍增器离子检测器。 离子检测器包括三个气体电子倍增器级GEM1,GEM2,GEM3,其中相对电极(12)被布置为与第一电子倍增器级GEM1相邻。
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公开(公告)号:US07829841B2
公开(公告)日:2010-11-09
申请号:US11718213
申请日:2005-11-03
Applicant: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
Inventor: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
CPC classification number: G01N27/622 , H01J49/0027 , H01J49/0031 , H01J49/004 , H01J49/0045 , H01J49/02 , H01J49/062 , H01J49/065 , H01J49/066 , H01J49/40 , H01J49/401 , H01J49/42
Abstract: A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (4) and an ion guide (6) arranged downstream of the ion mobility spectrometer or separator (4). A plurality of axial potential wells are created in the ion guide (6) so that ions received from the ion mobility spectrometer or separator (4) become confined in separate axial potential wells. The potential wells maintain the fidelity and/or composition of ions received from the ion mobility spectrometer or separator (4). The potential wells are translated along the length of the ion guide (6).
Abstract translation: 公开了一种质谱仪,其包括离子迁移谱仪或分离器(4)和布置在离子迁移谱仪或分离器(4)的下游的离子导向器(6)。 在离子导向器(6)中产生多个轴向势阱,使得从离子迁移谱仪或分离器(4)接收的离子被限制在单独的轴向势阱中。 潜在的孔维持从离子迁移谱仪或分离器(4)接收的离子的保真度和/或组成。 潜在的井沿离子导向件(6)的长度平移。
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公开(公告)号:US20100065737A1
公开(公告)日:2010-03-18
申请号:US11721260
申请日:2005-12-08
Applicant: Robert Harold Bateman , Kevin Giles , Jeffrey Mark Brown , Steven Derek Pringle , Jason Lee Wildgoose
Inventor: Robert Harold Bateman , Kevin Giles , Jeffrey Mark Brown , Steven Derek Pringle , Jason Lee Wildgoose
IPC: B01D59/44
CPC classification number: H01J49/062 , H01J49/004
Abstract: A mass spectrometer is disclosed comprising a mass selective ion trap or mass analyser (4) arranged upstream of an ion guide (6). Ions are scanned out of the mass selective ion trap or mass analyser (4) and are received in one or more axial potential wells created or formed within the ion guide (6). One or more transient DC voltages or potentials are preferably applied to the ion guide (6) in order to create a plurality of axial potential wells which are translated along the length of the ion guide (6). Ions are released in packets from the exit of the ion guide (6) and are orthogonally accelerated into a drift or flight region of an orthogonal acceleration Time of Flight mass analyser (13) with a relatively high duty cycle.
Abstract translation: 公开了一种质谱仪,其包括布置在离子导向器(6)上游的质量选择性离子阱或质量分析器(4)。 从质量选择性离子阱或质量分析器(4)中扫描离子,并将其接收在离子导向器(6)内产生或形成的一个或多个轴向势阱中。 优选地将一个或多个瞬态DC电压或电位施加到离子导向器(6),以便产生沿离子导向件(6)的长度平移的多个轴向势阱。 从离子导向器(6)的出口以分组的形式释放离子,并以相对较高的占空比正交加速到正交加速时间飞行质量分析器(13)的漂移或飞行区域。
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公开(公告)号:US20100001180A1
公开(公告)日:2010-01-07
申请号:US12302168
申请日:2007-06-01
Applicant: Robert Harold Bateman , Jeffery Mark Brown , Martin Green , Jason Lee Wildgoose , Anthony James Gilbert , Steven Derek Pringle
Inventor: Robert Harold Bateman , Jeffery Mark Brown , Martin Green , Jason Lee Wildgoose , Anthony James Gilbert , Steven Derek Pringle
CPC classification number: H01J49/0036 , G06K9/0053
Abstract: A Time of Flight mass analyser is disclosed comprising an ion detector comprising an Analogue to Digital Converter. Output signals from the ion detector are digitised and the arrival times and intensity values relating to ion arrival events are determined. If the determined arrival times from two signals fall within the same time window then the arrival times are added together in a weighted manner and the intensity values are combined.
Abstract translation: 公开了一种飞行时间质量分析仪,其包括离子检测器,该离子检测器包括模数转换器。 来自离子检测器的输出信号被数字化,确定与离子到达事件有关的到达时间和强度值。 如果从两个信号确定的到达时间落在相同的时间窗口内,则以加权的方式将到达时间相加在一起并且强度值被组合。
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公开(公告)号:US20090121123A1
公开(公告)日:2009-05-14
申请号:US11916438
申请日:2006-06-05
Applicant: Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
Inventor: Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
CPC classification number: H01J49/427 , H01J49/4235
Abstract: An ion guide or ion trap (1) is disclosed having an entrance electrode (2) and an exit electrode (3). The potential of the exit electrode (3) is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap (1) via an aperture in the exit electrode (3). The period of time that the potential of the exit electrode (3) is dropped for is progressively increased and ions emerge from the ion guide or ion trap (1) in a mass to charge ratio dependent manner. The ion guide or ion trap (1) may be operated as a mass separator or low resolution mass analyser.
Abstract translation: 公开了一种具有入口电极(2)和出口电极(3)的离子导向器或离子阱(1)。 出口电极(3)的电位周期性地下降相当短的时间段,允许一些离子通过出射电极(3)中的孔从离子导向器或离子阱(1)逸出。 退出电极(3)的电位下降的时间段逐渐增加,并且离子导向器或离子阱(1)以质荷比依赖的方式出现离子。 离子导向器或离子阱(1)可以作为质量分离器或低分辨率质量分析器来操作。
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公开(公告)号:US20080135746A1
公开(公告)日:2008-06-12
申请号:US11574554
申请日:2005-09-14
Applicant: Jason Lee Wildgoose , Steven Derek Pringle , Kevin Giles , Robert Harold Bateman
Inventor: Jason Lee Wildgoose , Steven Derek Pringle , Kevin Giles , Robert Harold Bateman
IPC: B01D59/44
CPC classification number: H01J49/005
Abstract: A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (3) arranged upstream of a collision or fragmentation cell (5). Ions are separated according to their ion mobility within the ion mobility spectrometer or separator (3). The kinetic energy of the ions exiting the ion mobility spectrometer or separator (3) is increased substantially linearly with time in order to optimise the fragmentation energy of ions as they enter the collision or fragmentation cell (5).
Abstract translation: 公开了一种质谱仪,其包括设置在碰撞或破碎电池(5)的上游的离子迁移谱仪或分离器(3)。 离子在离子迁移谱仪或分离器(3)内根据其离子迁移率分离。 离子离子迁移谱仪或分离器(3)离子的动能随时间呈线性增加,以优化离子进入碰撞或破碎电池(5)时的碎裂能。
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