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51.
公开(公告)号:US4202886A
公开(公告)日:1980-05-13
申请号:US902137
申请日:1978-05-02
申请人: Kazunori Ohba , Takashi Shomura , Yasuaki Ogawa , Takashi Tsuruoka , Hiroshi Watanabe , Takashi Hisamatsu , Shingo Uchida , Michio Kojima , Shigeharu Inouye
发明人: Kazunori Ohba , Takashi Shomura , Yasuaki Ogawa , Takashi Tsuruoka , Hiroshi Watanabe , Takashi Hisamatsu , Shingo Uchida , Michio Kojima , Shigeharu Inouye
CPC分类号: C12P1/06
摘要: An antibiotic SF-1942 substance produced by cultivating an SF-1942 substance producing strain of the genus Streptomyces in a nutrient medium under aerobic conditions to produce and accumulate the SF-1942 substance in the nutrient medium and isolating the SF-1942 substance from the fermentation broth followed by purification and a process for the production of the antibiotic SF-1942 substance. The SF-1942 substance is effective as an antimicrobial agent and an antitumor agent against Sarcoma 180 tumor cells in mice.
摘要翻译: 通过在营养培养基中在需氧条件下培养产生链霉菌属的SF-1942物质的菌株而产生的抗生素SF-1942物质,以在营养培养基中产生并积累SF-1942物质并从发酵中分离出SF-1942物质 肉汤,然后进行纯化和生产抗生素SF-1942物质的方法。 SF-1942物质作为抗微生物剂和抗小鼠肉瘤180肿瘤细胞的抗肿瘤剂是有效的。
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公开(公告)号:US4027014A
公开(公告)日:1977-05-31
申请号:US567867
申请日:1975-04-14
申请人: Norio Ezaki , Shoichi Amano , Shinji Miyado , Mitsugu Ito , Chuhei Nojiri , Takashi Tsuruoka , Yujiro Yamada , Taro Niida
发明人: Norio Ezaki , Shoichi Amano , Shinji Miyado , Mitsugu Ito , Chuhei Nojiri , Takashi Tsuruoka , Yujiro Yamada , Taro Niida
CPC分类号: A61K35/74 , C07G11/00 , Y10S435/874
摘要: A new antibiotic designated BN-130 substance is now provided, which has antibacterial activity against gram-negative and gram-positive bacteria as well as acid-fast bacteria. BN-130 substance is produced by cultivating a strain of Pseudomanas stutzeri under aerobic conditions.
摘要翻译: 现在提供了一种名为BN-130物质的新型抗生素,对抗革兰氏阳性菌和革兰氏阳性菌以及抗酸菌具有抗菌活性。 BN-130物质是通过在有氧条件下培养一种Pseudomanas stutzeri菌株产生的。
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公开(公告)号:US3956337A
公开(公告)日:1976-05-11
申请号:US508734
申请日:1974-09-24
申请人: Tomizo Niwa , Takashi Tsuruoka , Takashi Shomura , Shigeharu Inouye , Kazuo Saito , Taro Niida
发明人: Tomizo Niwa , Takashi Tsuruoka , Takashi Shomura , Shigeharu Inouye , Kazuo Saito , Taro Niida
IPC分类号: C12P19/00 , C07D211/76 , C12P17/06 , C12P17/12 , C07D211/74
CPC分类号: C07D211/76 , C12P17/12
摘要: D-Gluconic-.delta.-lactam is obtained by oxidizing nojirimycin with glucose-oxidizing enzymes or by the action of microorganisms capable of producing glucose-oxidizing enzymes.
摘要翻译: 通过用葡萄糖氧化酶氧化nojirimycin或通过能产生葡萄糖氧化酶的微生物的作用获得D-葡糖酸-δ-内酰胺。
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