公开(公告)号：US5643126A

公开(公告)日：1997-07-01

申请号：US627673

申请日：1996-04-01

申请人： Takashi Hotta ,  Kinji Marumo ,  Michio Kojima

发明人： Takashi Hotta ,  Kinji Marumo ,  Michio Kojima

IPC分类号： F16H3/44 ,  F16H57/04 ,  F16H57/08

CPC分类号： F16H57/0482 ,  F16H57/0479 ,  F16H57/082

摘要： A planetary gear mechanism includes a planetary carrier and pinions rotatably carried on the planetary carrier through pinion shafts. An annular lubricating oil supply member is mounted on a ring gear supporting member which supports a ring gear on its outer periphery and which is rotatable. The lubricating oil supply member has a plurality of fins formed radially thereon. The lubricating oil received within the lubricating oil supply member while submerged in the lubricating oil is scattered by a centrifugal force and supplied to oil reservoirs defined in the adjacent side of the planetary carrier and then from the oil reservoirs via oil passages in the pinion shafts to the needle bearing which supports the pinions. With the above construction, it is possible to effectively supply the lubricating oil to the pinion shafts of the planetary gear mechanism when the planetary is in a fixed position.

摘要翻译： 行星齿轮机构包括行星架和通过小齿轮轴可旋转地承载在行星架上的小齿轮。 环形润滑油供给部件安装在环形齿轮支撑部件上，该齿圈支撑部件在其外周上支撑环形齿轮并且可旋转。 润滑油供给部件具有径向地形成的多个翅片。 润滑油供给部件内的润滑油在浸没在润滑油中时被离心力散射，供给到在行星齿轮架的相邻侧限定的油箱，然后通过小齿轮轴上的油路从储油器传递到 支撑小齿轮的滚针轴承。 通过上述结构，当行星齿轮处于固定位置时，能够有效地将润滑油供给行星齿轮机构的小齿轮轴。

公开(公告)号：US4396603A

公开(公告)日：1983-08-02

申请号：US313370

申请日：1981-10-21

申请人： Norio Ezaki ,  Takashi Shomura ,  Shoichi Amano ,  Tomizo Niwa ,  Michio Kojima ,  Tatsuo Ito

发明人： Norio Ezaki ,  Takashi Shomura ,  Shoichi Amano ,  Tomizo Niwa ,  Michio Kojima ,  Tatsuo Ito

IPC分类号： C12P1/06 ,  A61K35/00 ,  C12P1/02

CPC分类号： C12R1/01 ,  C12P1/06

摘要： Disclosed is a novel antibiotic SF-2107 series substance consisting essentially of Substance SF-2107 A-1, Substance SF-2107 B and/or Substance SF-2107 C, each having the phisico-chemical properties as described in the specification, which substance exhibits an antibacterial activity against both gram-positive and gram-negative bacteria and is useful for pharmaceuticals, bactericides, disinfectants, etc. Also disclosed is a process for preparing the substance.

摘要翻译： 公开了一种基本上由物质SF-2107A-1，物质SF-2107B和/或物质SF-2107C组成的新型抗生素SF-2107系列物质，它们各自具有说明书所述的物理化学性质，该物质 对革兰氏阳性细菌和革兰氏阴性细菌均具有抗菌活性，并且可用于药物，杀菌剂，消毒剂等。还公开了制备该物质的方法。

公开(公告)号：US4376778A

公开(公告)日：1983-03-15

申请号：US218975

申请日：1980-12-22

申请人： Norio Ezaki ,  Takashi Shomura ,  Tomizo Niwa ,  Michio Kojima ,  Shigeharu Inouye ,  Tatsuo Ito

发明人： Norio Ezaki ,  Takashi Shomura ,  Tomizo Niwa ,  Michio Kojima ,  Shigeharu Inouye ,  Tatsuo Ito

IPC分类号： C07G11/00 ,  A01N43/36 ,  A61K31/40 ,  A61K35/74 ,  A61P31/00 ,  A61P31/04 ,  C07D207/42 ,  C07D233/66 ,  C07D233/68 ,  C07D233/91 ,  C12P1/06 ,  C12P17/10 ,  C12R1/465

CPC分类号： C12R1/465 ,  C07D207/42 ,  C12P17/10

摘要： Antibiotics, designated as SF-2080A substance and SF-2080B substance, are described, and are obtained by cultivating an SF-2080 substance-producing strain belonging to the genus Streptomyces, for example, Streptomyces sp. SF-2080 (FERM-P No. 5072, ATCC No. 31673), in a nutrient medium, and recovering the desired substance from the culture.

摘要翻译： 描述了称为SF-2080A物质和SF-2080B物质的抗生素，通过培养属于链霉菌属的SF-2080物质生产菌株，例如链霉菌属（Streptomyces sp。）， 在营养培养基中的SF-2080（FERM-P No.5072，ATCC No.31673），并从培养物中回收所需物质。

公开(公告)号：US4202886A

公开(公告)日：1980-05-13

申请号：US902137

申请日：1978-05-02

申请人： Kazunori Ohba ,  Takashi Shomura ,  Yasuaki Ogawa ,  Takashi Tsuruoka ,  Hiroshi Watanabe ,  Takashi Hisamatsu ,  Shingo Uchida ,  Michio Kojima ,  Shigeharu Inouye

发明人： Kazunori Ohba ,  Takashi Shomura ,  Yasuaki Ogawa ,  Takashi Tsuruoka ,  Hiroshi Watanabe ,  Takashi Hisamatsu ,  Shingo Uchida ,  Michio Kojima ,  Shigeharu Inouye

IPC分类号： C07G11/00 ,  A61K35/74 ,  A61P31/00 ,  A61P31/04 ,  A61P35/00 ,  C12P1/06 ,  C12R1/465

CPC分类号： C12P1/06

摘要： An antibiotic SF-1942 substance produced by cultivating an SF-1942 substance producing strain of the genus Streptomyces in a nutrient medium under aerobic conditions to produce and accumulate the SF-1942 substance in the nutrient medium and isolating the SF-1942 substance from the fermentation broth followed by purification and a process for the production of the antibiotic SF-1942 substance. The SF-1942 substance is effective as an antimicrobial agent and an antitumor agent against Sarcoma 180 tumor cells in mice.

摘要翻译： 通过在营养培养基中在需氧条件下培养产生链霉菌属的SF-1942物质的菌株而产生的抗生素SF-1942物质，以在营养培养基中产生并积累SF-1942物质并从发酵中分离出SF-1942物质 肉汤，然后进行纯化和生产抗生素SF-1942物质的方法。 SF-1942物质作为抗微生物剂和抗小鼠肉瘤180肿瘤细胞的抗肿瘤剂是有效的。

公开(公告)号：US4160026A

公开(公告)日：1979-07-03

申请号：US826766

申请日：1977-08-22

申请人： Katsuyoshi Iwamatsu ,  Shoji Omoto ,  Takashi Shomura ,  Hiroshi Watanabe ,  Michio Kojima ,  Shigeharu Inoue ,  Taro Niida ,  Takashi Hisamatsu ,  Shingo Uchida

发明人： Katsuyoshi Iwamatsu ,  Shoji Omoto ,  Takashi Shomura ,  Hiroshi Watanabe ,  Michio Kojima ,  Shigeharu Inoue ,  Taro Niida ,  Takashi Hisamatsu ,  Shingo Uchida

IPC分类号： C12P13/00 ,  A61K35/74 ,  A61P31/04 ,  A61P37/04 ,  C07G11/00 ,  C07H5/06 ,  C12P1/06 ,  C12P19/04 ,  C12D9/14

CPC分类号： C07H5/06 ,  C07G11/00 ,  C12P1/06 ,  Y10S435/886

摘要： New antibiotics SF-1130-x.sub.1 substance and SF-1130-x.sub.2 substance are produced by cultivating a microorganism Streptomyces myxogenes SF-1130 now deposited under FERM-P. 676 and ATCC. 31305 in a liquid culture medium under aerobic conditions, and these antibiotics may be isolated from the fermentation broth and are useful as an activator for enhancing the host defense system in living animals. The activity of these antibiotics may be improved when used in combination with one or more of maltose, maltotriose, maltotetraose, maltopentaose, maltohexaose and maltoheptaose.

摘要翻译： 新型抗生素SF-1130-x1物质和SF-1130-x2物质是通过培养现在以FERM-P沉积的微生物Streptomyces myxogenes SF-1130生产的。 676和ATCC。 31305在有氧条件下在液体培养基中，这些抗生素可以从发酵液中分离出来，可用作增强活体动物宿主防御系统的活化剂。 当与麦芽糖，麦芽三糖，麦芽四糖，麦芽五糖，麦芽六糖和麦芽七糖中的一种或多种组合使用时，可以改善这些抗生素的活性。

公开(公告)号：US4076588A

公开(公告)日：1978-02-28

申请号：US703589

申请日：1976-07-08

申请人： Shigeharu Inouye ,  Takashi Shomura ,  Michio Kojima ,  Yasuaki Ogawa ,  Hiroshi Watanabe ,  Yasumitsu Kondo ,  Kazuo Saito, deceased ,  Yujiro Yamada ,  Taro Niida

发明人： Shigeharu Inouye ,  Takashi Shomura ,  Michio Kojima ,  Yasuaki Ogawa ,  Hiroshi Watanabe ,  Yasumitsu Kondo ,  Kazuo Saito, deceased ,  Yujiro Yamada ,  Taro Niida

IPC分类号： A61K35/74 ,  C07D501/36 ,  C07D501/57 ,  C12P1/06 ,  C12P35/08 ,  C12D9/14

CPC分类号： C12P35/08 ,  Y10S435/803 ,  Y10S435/893 ,  Y10S435/929

摘要： A new antibiotic designated as SF-1623 substance exhibiting a useful antibacterial activity against gram-negative bacteria is now produced by cultivating a new strain ATCC 21999 of the known species Streptomyces chartreusis. The SF-1623 substance in the form of its an alkali metal salt may be recovered from the culture when the cultivation is effected under aerobic conditions in the presence of an alkali metal thiosulfate.

摘要翻译： 现在通过培育已知种类的链霉菌Streptomyces chartreusis的新菌株ATCC 21999，产生一种被指定为对革兰氏阴性细菌有用的抗菌活性的SF-1623物质的新抗生素。 当在有氧条件下在碱金属硫代硫酸盐存在下进行培养时，可以从培养物中回收其碱金属盐形式的SF-1623物质。

公开(公告)号：US3974035A

公开(公告)日：1976-08-10

申请号：US552281

申请日：1975-02-24

申请人： Takashi Shomura ,  Hiroshi Watanabe ,  Yasuaki Ogawa ,  Kazunori Ohba ,  Yasumitsu Kondo ,  Michio Kojima ,  Shigeharu Inoje ,  Taro Niida

发明人： Takashi Shomura ,  Hiroshi Watanabe ,  Yasuaki Ogawa ,  Kazunori Ohba ,  Yasumitsu Kondo ,  Michio Kojima ,  Shigeharu Inoje ,  Taro Niida

IPC分类号： A61K31/545 ,  A61P31/04 ,  C12P35/08 ,  C12D9/14

CPC分类号： C12P35/08 ,  Y10S435/893

摘要： This invention relates to a process for preparing a cephamycin type antibiotic substance which comprises cultivating a microorganism belonging to the genus Streptomyces under aerobic conditions and a primary object of this invention is to provide a process for preparing the said product on a simple and industrial scale.

摘要翻译： 本发明涉及一种制备头孢霉素型抗生素物质的方法，该方法包括在需氧条件下培养属于链霉菌属的微生物，本发明的主要目的是提供以简单和工业规模制备所述产品的方法。

公开(公告)号：US4404218A

公开(公告)日：1983-09-13

申请号：US293063

申请日：1981-08-17

申请人： Tatsuo Ito ,  Takashi Shomura ,  Michio Kojima ,  Norio Ezaki ,  Masaji Sezaki ,  Tomizo Niwa

发明人： Tatsuo Ito ,  Takashi Shomura ,  Michio Kojima ,  Norio Ezaki ,  Masaji Sezaki ,  Tomizo Niwa

IPC分类号： C12P1/06 ,  C07D477/20 ,  C12P17/18 ,  C07D487/04 ,  A61K31/40

CPC分类号： C12R1/465 ,  C07D477/20 ,  C12P17/184

摘要： An antibiotic SF-2103A substance or a salt thereof, and a process for the production thereof are described, and the process comprises cultivating an antibiotic SF-2103A substance-producing strain in a nutrient medium and recovering the desired substance from the culture broth.

摘要翻译： 描述了抗生素SF-2103A物质或其盐及其制备方法，该方法包括在营养培养基中培养抗生素SF-2103A物质生产菌株并从培养液中回收所需物质。

公开(公告)号：US4242327A

公开(公告)日：1980-12-30

申请号：US89924

申请日：1979-10-31

申请人： Kazunori Ohba ,  Takashi Shomura ,  Michio Kojima ,  Shoji Omoto ,  Takashi Tsuruoka ,  Shigeharu Inoue

发明人： Kazunori Ohba ,  Takashi Shomura ,  Michio Kojima ,  Shoji Omoto ,  Takashi Tsuruoka ,  Shigeharu Inoue

IPC分类号： C07H15/224 ,  A61K31/70 ,  A61K31/7028 ,  A61K31/7034 ,  A61K31/7036 ,  A61K35/74 ,  A61P31/04 ,  A61P35/00 ,  C07G11/00 ,  C07H15/232 ,  C12P1/06 ,  C12P19/48 ,  C12R1/01 ,  A61K35/00

CPC分类号： C12R1/01 ,  C07H15/232 ,  C12P19/48

摘要： New antibiotic, SF-2052 substance is produced by cultivating a microorganism, Dactylosporangium matsuzakiense SF-2052 now deposited under FERM-P 4670 or ATCC No. 31570 in a liquid culture medium under aerobic conditions, and this antibiotic may be isolated from the culture broth by conventional method and is useful as antibacterial agent.

摘要翻译： 新型抗生素SF-2052物质是通过在有氧条件下在液体培养基中培养微生物Dormylosporangium matsuzakiense SF-2052生产的，现在将其储存在FERM-P 4670或ATCC No.37070中，该抗生素可以从培养液中分离 通过常规方法可用作抗菌剂。

公开(公告)号：US4209509A

公开(公告)日：1980-06-24

申请号：US8406

申请日：1979-02-01

申请人： Shigeharu Inouye ,  Takashi Shomura ,  Michio Kojima ,  Takashi Hisamatsu

发明人： Shigeharu Inouye ,  Takashi Shomura ,  Michio Kojima ,  Takashi Hisamatsu

IPC分类号： C12P1/06 ,  A61K35/00

CPC分类号： C12P1/06

摘要： Substance SF-1739 derivatives, Substance SF-1739 HP, Substance SF-1739 HP-C, Substance SF-1739 HP-F, Substance SF-1739 HP-3 and Substance SF-1739 HP-5, the physico-chemical properties of which derivatives are described in the specification; processes for preparing such SF-1739 derivatives; and antimicrobial compositions containing at least one of the said Substance SF-1739 derivatives.

摘要翻译： 物质SF-1739衍生物，物质SF-1739 HP，物质SF-1739 HP-C，物质SF-1739 HP-F，物质SF-1739 HP-3和物质SF-1739 HP-5，物理化学性质 说明书中描述了哪些衍生物; 制备这种SF-1739衍生物的方法; 和含有至少一种所述物质SF-1739衍生物的抗微生物组合物。