-
公开(公告)号：US20170106213A1
公开(公告)日：2017-04-20
申请号：US15391494
申请日：2016-12-27
申请人： W. Davis Lee , Mark R. Amato , Nick Ruebel , Jillian Reno
发明人： W. Davis Lee , Mark R. Amato , Nick Ruebel , Jillian Reno
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/1051 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a fiducial marker-fiducial detector based treatment room position determination/positioning system apparatus and method of use thereof. Generally, a set of fiducial marker detectors detect photons emitted from and/or reflected off of a set of fiducial markers positioned on one or more objects in a treatment room and resultant determined distances and/or calculated angles are used to determine relative positions of multiple objects or elements in the treatment room. Position of the mapped objects is used in: (1) imaging, such as X-ray, positron emission tomogram, and/or proton beam imaging and/or (2) beam targeting and treatment, such as proton based cancer treatment. As relative positions of objects in the treatment room are dynamically determined using the fiducial marking system, engineering and/or mathematical constraints of a treatment beamline isocenter are removed.
-
公开(公告)号：US11643706B2
公开(公告)日：2023-05-09
申请号：US16523974
申请日：2019-07-26
申请人： W. Davis Lee , Mark R. Amato
发明人： W. Davis Lee , Mark R. Amato
摘要： The invention comprises a method and apparatus for generating a rare earth from a rare earth oxide, comprising the sequential steps of: (1) reducing temperature about the rare earth oxide to less than zero degrees Celsius; (2) reducing pressure to boil off contaminant water in a powder sample of the rare earth oxide at a molecular escape velocity not disturbing the powdered rare earth oxide; and (3) heating the rare earth oxide to greater than 1000° C. in the presence hydrogen gas while optionally: (1) collecting and determining mass of a water product to determine a consumption mass of the starting hydrogen gas in a main reaction process using the equation RE2O3+3H2→2RE+3H2O, wherein “RE” comprises at a rare earth and (2) injecting replacement hydrogen gas into the main reaction chamber up to the consumption mass.
-
53.发明授权公开(公告)号：US11185717B2
公开(公告)日：2021-11-30
申请号：US16434123
申请日：2019-06-06
申请人： Jillian Reno , Armin Huseinovic , Mark R. Amato , Daniel J. Raymond , W. Davis Lee , Lou Wainwright , James P. Bennett
发明人： Jillian Reno , Armin Huseinovic , Mark R. Amato , Daniel J. Raymond , W. Davis Lee , Lou Wainwright , James P. Bennett
摘要： The invention comprises a segmented rolling floor apparatus and method of use thereof, such as for use in a charged particle cancer therapy system. The segmented rolling floor comprises a first spool and a second spool, attached to opposite ends of the rolling floor, which cooperatively wind and unwind the rolling floor. The segmented rolling floor circumferentially surrounds a nozzle system penetrating through an aperture in the segmented rolling floor, where the nozzle system is used to deliver charged particles, from an accelerator, to a tumor of a patient. The rolling floor and nozzle systems move at respective rates maintaining the nozzle system in the aperture allowing for a safe/walkable floor while allowing treatment of the tumor as a gantry rotates the nozzle system and delivers protons to the tumor from positions above and below the floor.
-
公开(公告)号：US20210025025A1
公开(公告)日：2021-01-28
申请号：US16523970
申请日：2019-07-26
申请人： W. Davis Lee , Mark R. Amato
发明人： W. Davis Lee , Mark R. Amato
摘要： The invention comprises an apparatus and method of use thereof for generating a rare earth from a rare earth oxide, comprising the steps of: (1) dissociating the rare earth oxide and hydrogen gas in a reaction chamber by inductively heating the reaction chamber to greater than 2000° K to form the associated rare earth and water vapor in a reaction process; (2) driving the reaction process forward by removing the water vapor from the reaction chamber by condensing and freezing the water vapor on a first cold trap surface as water ice, where the reaction comprises: RE2O3+3H2→2RE+3H2O, where REO is a rare earth oxide and RE comprises a rare earth in the rare earth oxide; and/or (3) monitoring the reaction process by monitoring generation of at least one of the rare earth and the water in a control system designed for continuous/semi-continuous operation.
-
55.发明授权公开(公告)号：US10792517B2
公开(公告)日：2020-10-06
申请号：US15823148
申请日：2017-11-27
摘要： The invention comprises a method and apparatus for determining state of a positively charged particle, such as a proton, for use in imaging a tumor of a patient prior to and/or concurrent with cancer therapy. The imaging system comprises: (1) a beam transport path of the positively charged particle sequentially passing through a patient, through a first time of flight detector, and, after traversing a pathlength, at least into a second time of flight detector and (2) a beam state determination system using elapsed time between detection at the first and second time of flight detectors and the pathlength to determine a residual beam energy, which, when compared to a known incident beam energy, is used in generation of an image of the tumor. An optional beam energy degrading element increases time differences between the time of flight detectors.
-
公开(公告)号：US10684380B2
公开(公告)日：2020-06-16
申请号：US15240974
申请日：2016-08-18
申请人： W. Davis Lee , Mark R. Amato
发明人： W. Davis Lee , Mark R. Amato
摘要： Generally, a method or apparatus for tomographically imaging a sample, such as a tumor of a patient, using positively charged particles positions n two-dimensional detector arrays on n surfaces of a scintillation material or scintillator, respectively. Resultant from energy transfer from the positively charged particles, secondary photons are emitted from the scintillation material and detected by the plurality of two-dimensional detector arrays, where each detector array images the scintillation material. Combining signals from the plurality of two-dimensional detector arrays, the path, position, energy, and/or state of the positively charged particle beam as a function of time and/or rotation of the patient relative to the positively charged particle beam is determined and used in tomographic reconstruction of an image of the sample or the tumor.
-
57.发明申请公开(公告)号：US20200038681A1
公开(公告)日：2020-02-06
申请号：US16601592
申请日：2019-10-15
申请人： Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
发明人： Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
摘要： The invention comprises a method and apparatus for scanning charged particles in a cancer therapy system, comprising the steps of: (1) providing a first and second dipole magnet system and a gap, the gap comprising a common gap length, along a path of the charged particles, within both the first and second dipole magnet systems, the gap comprising a progressively increasing x/y-plane cross-section area from an entrance area of the charged particles into the double dipole magnet system to an exit area of the double dipole magnet system, the x/y-plane perpendicular to a z-axis from a center of the entrance area to a center of the exit area; (2) scanning the positively charged particles along a first axis of the x/y-plane using the first dipole magnet system; and (3) scanning the positively charged particles along a second axis of the x/y-plane using the second dipole magnet system.
-
58.发明授权公开(公告)号：US10518109B2
公开(公告)日：2019-12-31
申请号：US15459854
申请日：2017-03-15
申请人： Jillian Reno , Susan L. Michaud , Nick Ruebel , Mark R. Amato , W. Davis Lee , James P. Bennett
发明人： Jillian Reno , Susan L. Michaud , Nick Ruebel , Mark R. Amato , W. Davis Lee , James P. Bennett
摘要： The invention comprises a method and apparatus for determining a radiation beam treatment path to a tumor, comprising the steps of: (1) delivering charged particles from an accelerator, along a first beam transport path, through an output nozzle, and along a treatment path to the tumor relative to a calibrated reference beam path from the output nozzle toward a patient position and (2) prior to the step of delivering, a main controller verifying an unobstructed linear path of the treatment path using a set of fiducial indicators positioned at least: on a first element physically affixed and co-movable with the output nozzle and on a moveable object in the treatment room. Optionally, voxels of the treatment beam path and potentially obstructing objects are defined in the treatment room using an axis system relative to the calibrated reference beam path and a reference beam point.
-
公开(公告)号：US20190351259A1
公开(公告)日：2019-11-21
申请号：US16526868
申请日：2019-07-30
申请人： W. Davis Lee , Mark R. Amato
发明人： W. Davis Lee , Mark R. Amato
摘要： The invention comprises a method and apparatus for reducing a kinetic energy of positively charged particles, comprising the steps of: (1) transporting the positively charged particles from an accelerator into an exit nozzle system along a beam line; (2) providing a first chamber of the exit nozzle system, the first chamber comprising: an incident side comprising an incident aperture, an exit side comprising an exit aperture, and a beam path of the positively charged particles from the incident aperture to the exit aperture; (3) filling the beam path in the chamber with a liquid; and (4) using the liquid to reduce the kinetic energy of the positively charged particles. The kinetic energy dissipater is optionally used in combination with a proton therapy cancer treatment system and/or a proton tomography imaging system.
-
60.发明申请公开(公告)号：US20190351258A1
公开(公告)日：2019-11-21
申请号：US16526978
申请日：2019-07-30
申请人： Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
发明人： Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
摘要： The invention comprises a method and apparatus for steering/scanning charged particles, comprising: a double dipole scanning system, comprising: (1) a beam path chamber comprising an entrance side and an exit side, the entrance side comprising a smaller area than the exit side; (2) a first dipole magnet, the first dipole magnet comprising a first coil and a third coil on first opposite sides of the beam path chamber; and (3) a second dipole magnet, the second dipole magnet comprising a second coil and a fourth coil on second opposite sides of the beam path chamber, the beam path chamber further comprising a truncated square/rectangle pyramid shape, the smaller entrance side of the charged particles comprising a top of the truncated pyramid shape, the exit side of the charged particles comprising a larger bottom of the truncated pyramid shape.
-
-
-
-
-
-
-
-
-
搜索结果
144 条记录 (耗时 0.053 秒)
