Method and assay using inactivation of factors Va and VIIIa by activated
Protein C to diagnose thrombic disease or assay for Protein C and kit
therefor
    65.
    发明授权
    Method and assay using inactivation of factors Va and VIIIa by activated Protein C to diagnose thrombic disease or assay for Protein C and kit therefor 失效
    通过活化的蛋白C使因子Va和VIIIa失活以诊断血栓疾病或蛋白C及其试剂盒的方法和测定法

    公开(公告)号:US5051357A

    公开(公告)日:1991-09-24

    申请号:US396234

    申请日:1989-08-21

    IPC分类号: C12Q1/56 G01N33/86

    CPC分类号: C12Q1/56 G01N33/86

    摘要: A method and test kit for indirectly assaying for Protein C is described. The method uses tissue thrombomodulin/tissue factor (TTP) and calcium chloride to produce thrombin and activate Protein C to Protein Ca without fibrin formation and then allows time for Protein Ca to inactivate Factors Va and VIIIa. A deficient plasma has a decreased activated thromboplastin assay clotting time compared to a control plasma. The method and test kit is used to diagnose thrombic diseases.

    摘要翻译: 描述了用于间接测定蛋白C的方法和测试试剂盒。 该方法使用组织血栓调节素/组织因子(TTP)和氯化钙来产生凝血酶,并将蛋白C活化到蛋白质Ca,而不形成纤维蛋白,然后允许蛋白质Ca失活因子Va和VIIIa的时间。 与对照血浆相比,缺乏血浆的活化凝血活酶凝血酶测定凝血时间降低。 方法和检测试剂盒用于诊断血栓性疾病。

    Coaxial cavity type, radiofrequency wave, plasma generating apparatus
    66.
    发明授权
    Coaxial cavity type, radiofrequency wave, plasma generating apparatus 失效
    同轴腔型,射频波,等离子体发生装置

    公开(公告)号:US4906900A

    公开(公告)日:1990-03-06

    申请号:US331754

    申请日:1989-04-30

    申请人: Jes Asmussen

    发明人: Jes Asmussen

    CPC分类号: H05H1/46 C30B23/02

    摘要: A coaxial radiofrequency wave plasma generating apparatus with an elongate metallic cavity (10) having a movable elongate coupling probe (16) mounted in line with an axis (a--a) of the cavity having a central coaxial conductor (11) and having a movable plate (12) for obtaining a mode of resonance of the radiofrequency wave in the cavity surrounding a chamber (14) for confining the plasma (100) is described. An end (11b) of the conductor is adjacent to the chamber and can optionally support a set of magnets (27). The apparatus is particularly useful for retrofitting existing vacumm sources (101) having small inlet ports (105) for plasma treatment using molecular beam epitaxy (MBE).

    Joint transform image correlation using a nonlinear spatial light
modulator at the fourier plane
    67.
    发明授权
    Joint transform image correlation using a nonlinear spatial light modulator at the fourier plane 失效
    在傅立叶平面上使用非线性空间光调制器进行联合变换图像相关

    公开(公告)号:US4832447A

    公开(公告)日:1989-05-23

    申请号:US128803

    申请日:1987-12-04

    申请人: Bahram Javidi

    发明人: Bahram Javidi

    IPC分类号: G01N21/956 G06E3/00

    摘要: The present invention is a nonlinear joint transform image correlator which employs a spatial modulator operating in a binary mode at the Fourier plane. The reference and input images are illuminated by a coherent light at the object plane of a Fourier transform lens system. A image detection device, such as a charge coupled device, is disposed at the Fourier plane of this Fourier transform lens system. A thresholding network detects the median intensity level of the imaging cells of the charge coupled device at the Fourier plane and binarizes the Fourier transform interference intensity. The correlation output is formed by an inverse Fourier transform of this binarized Fourier transform interference intensity. In the preferred embodiment this is achieved via a second Fourier transform lens system. This binary data is then applied to spatial light modulator device operating in a binary mode located at the object plane of a second Fourier transform lens system. This binary mode spatial light modulator device is illuminated by coherent light producing the correlation output at the Fourier plane of the second Fourier transform lens system. The inverse Fourier transform may also be formed via a computer. In an alternative embodiment, the Fourier transform interference intensity is thresholded into one of three ranges. An inverse Fourier transform of this trinary Fourier transform interference intensity produces the correlation output.

    摘要翻译: 本发明是一种非线性联合变换图像相关器,其采用在傅立叶平面上以二进制模式操作的空间调制器。 参考和输入图像由傅立叶变换透镜系统的物平面上的相干光照亮。 诸如电荷耦合器件的图像检测器件设置在该傅里叶变换透镜系统的傅立叶平面上。 阈值网络检测傅立叶平面上的电荷耦合器件的成像单元的中值强度水平,并对傅里叶变换干扰强度进行二值化。 相关输出由这种二值化傅里叶变换干扰强度的傅里叶逆变换形成。 在优选实施例中,这通过第二傅里叶变换透镜系统来实现。 然后将该二进制数据应用于以位于第二傅里叶变换透镜系统的物平面的二进制模式工作的空间光调制器装置。 该二进制模式空间光调制器装置被相干光照亮,产生在第二傅立叶变换透镜系统的傅立叶平面处的相关输出。 也可以通过计算机形成逆傅立叶变换。 在替代实施例中,傅里叶变换干扰强度被阈值化为三个范围之一。 该三维傅立叶变换干涉强度的傅立叶逆变换产生相关输出。

    Collimator apparatus and method
    68.
    发明授权
    Collimator apparatus and method 失效
    准直仪器和方法

    公开(公告)号:US4739173A

    公开(公告)日:1988-04-19

    申请号:US896730

    申请日:1986-08-15

    IPC分类号: A61N5/10 G21K1/02 G21K1/04

    CPC分类号: G21K1/02 A61N5/1045 G21K1/04

    摘要: A collimator apparatus (10 or 100) including one or more bundles of nested rods (11, 11a or 101 or 101a or 201) which define a surface (112, 112a) which interferes with a beam of radiation is described. The apparatus particularly uses coil spring (48) between and along the axis (a--a or c--c) of the rods which are compressed by blocks (13, 14, 13a and 14a or 103, 104, 103a and 104a) to lock the rods in position in holes in the blocks. The apparatus is particularly useful for shaping radiation beams for patient treatment.

    摘要翻译: 描述了包括限定了与辐射束干涉的表面(112,112a)的一个或多个嵌套棒(11,11a或101或101a或201)束的准直器装置(10或100)。 该设备特别地使用螺旋弹簧(48),该螺旋弹簧(48)沿着由杆(13,14,13a和14a或103,104,103a和104a)压缩的杆的轴线(aa或cc)并沿其轴线(aa或cc),以将杆锁定在适当位置 在洞中的块。 该装置特别适用于形成用于患者治疗的辐射束。

    Methods and apparatus for determining cardiac output and left atrial pressure
    70.
    发明授权
    Methods and apparatus for determining cardiac output and left atrial pressure 有权
    用于测定心输出量和左心房压力的方法和装置

    公开(公告)号:US07666144B2

    公开(公告)日:2010-02-23

    申请号:US11358379

    申请日:2006-02-21

    IPC分类号: A61B5/02

    摘要: Method and apparatus are introduced for determining proportional cardiac output (CO), absolute left atrial pressure (LAP), and/or other important hemodynamic variables from a contour of a circulatory pressure waveform or related signal. Certain embodiments of the invention provided herein include the mathematical analysis of a pulmonary artery pressure (PAP) waveform or a right ventricular pressure (RVP) waveform in order to determine beat-to-beat or time-averaged proportional CO, proportional pulmonary vascular resistance (PVR), and/or LAP. The invention permits continuous and automatic monitoring of critical hemodynamic variables with a level of invasiveness suitable for routine clinical application. The invention may be utilized, for example, to continuously monitor critically ill patients with pulmonary artery catheters installed and chronically monitor heart failure patients instrumented with implanted devices for measuring RVP.

    摘要翻译: 引入方法和装置,用于根据循环压力波形或相关信号的轮廓确定比例心输出量(CO),绝对左心房压力(LAP)和/或其他重要血液动力学变量。 本文提供的本发明的某些实施方案包括肺动脉压力(PAP)波形或右心室压力(RVP)波形的数学分析,以便确定搏动搏动或时间平均比例CO,比例肺血管阻力( PVR)和/或LAP。 本发明允许以适合常规临床应用的侵入水平连续和自动监测关键血液动力学变量。 本发明可以用于例如连续监测安装的肺动脉导管的危重病人,并长期监测用植入装置测量RVP的心力衰竭患者。