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公开(公告)号:US20230037160A1
公开(公告)日:2023-02-02
申请号:US17953407
申请日:2022-09-27
Inventor: Michele Viola Manuel , Ida E. Svensson Berglund , Benjamin G. Keselowsky , Malisa Sarntinoranont , Harpreet Singh Brar , Hunter B. Henderson
Abstract: Embodiments of the present disclosure provide for structures including an alloy of calcium, strontium, and magnesium.
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公开(公告)号:US20230022747A1
公开(公告)日:2023-01-26
申请号:US17875552
申请日:2022-07-28
Inventor: Jenshan Lin , Lawrence Fomundam
Abstract: Various examples are provided for wireless power transfer to implants. In one example, a system includes a radio frequency (RF) power source and a transmitter (TX) array comprising an excitation coil and resonant coils distributed about the excitation coil. The TX array can transfer power from the RF power source to a biomedical implant inserted below a skin surface of a subject when the TX array is positioned on the skin surface adjacent to the biomedical implant. A receiver (RX) coil of the biomedical implant can inductively couple with the TX array for the power transfer. The resonant coils can allow power transfer when the RX coil is not aligned with the excitation coil.
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公开(公告)号:US11549897B2
公开(公告)日:2023-01-10
申请号:US17389601
申请日:2021-07-30
Inventor: Swarup Bhunia , Naren Vikram Raj Masna , Soumyajit Mandal , David Joseph Ariando
Abstract: An exemplary integrated nuclear quadrupole resonance-based detection system comprises a front-end device having a hand-held form factor, wherein the front-end device is configured to scan a sample in or near a sample coil using inbuild electronics and acquire a nuclear quadrupole resonance measurement. The system further includes a swappable sample coil that is attached to an opening at a face of the front-end device and is tuned to a resonant frequency of the sample; and a swappable impedance matching network that is attached to the opening at the face of the front-end device and is configured to tune the resonant frequency of the sample coil. The inbuild electronics comprises a wireless transfer module that is configured to communicate the acquired nuclear quadrupole resonance measurement with a back-end device of the integrated nuclear quadrupole resonance-based detection system. Other systems and methods are also provided.
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公开(公告)号:US20230003657A1
公开(公告)日:2023-01-05
申请号:US17901286
申请日:2022-09-01
Inventor: Peng Jiang , Zhuxiao GU , Sin-Yen LEO
IPC: G01N21/78
Abstract: Described are chromogenic sensors, methods of use, and kits including sensors. The sensors can have a polymer structure with a waveform cross-section in a programmed state. Upon exposure to a first liquid, the polymer structure in the programmed state changes to polymer structure in an activated state. Methods for measuring the presence of a liquid using the sensor are described, as are kits including the sensors.
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公开(公告)号:US20220409257A1
公开(公告)日:2022-12-29
申请号:US17286015
申请日:2019-08-28
Inventor: John N. Catanzaro , Michele Dill , Christopher Batich
Abstract: A flexible catheter is inserted into the esophagus to cool or warm the esophagus, particularly during certain procedures which can tend to change the temperature in the area of the esophagus. The catheter is inserted through the mouth and throat to a position, for example, proximate the heart, but within the esophagus. One or more balloons are inflated to block areas of the esophagus, while a gel is injected into the esophagus where it is immobilized by the one or more balloons. A coolant is pumped through a coolant tube affixed to the catheter, where it exchanges heat with the conductive gel.
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公开(公告)号:US20220387660A1
公开(公告)日:2022-12-08
申请号:US17772709
申请日:2020-11-06
Inventor: Nicholas J. Abuid , Jiapu Liang , Cherie Stabler
IPC: A61L15/44
Abstract: The present disclosure provides for oxygen generating and free radical scavenging biomaterials, an article including the oxygen generating and free radical scavenging biomaterial, wound healing dressings or structures (e.g., bandage) that have the characteristic of generating oxygen and having redox modulating capabilities. In particular, the wound healing dressing can have the characteristics of being anti-inflammatory, antioxidant, and pro-healing for extended periods of time (e.g., at least 10 days, at least 30 days).
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公开(公告)号:US11521076B2
公开(公告)日:2022-12-06
申请号:US16024389
申请日:2018-06-29
Inventor: Gregory M. Stitt , David M. Campbell , Raz Aloni , Thomas Vaseliou , Jayson Salkey
Abstract: Systems and methods for discovering approximations for compilers to apply through genetic programming and deterministic symbolic regression heuristics are provided. A method for discovering approximations for compilers and runtime optimization can include profiling a program to identify performance critical functions, determining appropriate candidates for approximation and developing application and architecture specific approximations through machine learning techniques, genetic programming, and deterministic heuristics. Such approximations can target any optimization goal, with a primary emphasis on parallelism, or can provide a set of Pareto-optimal tradeoffs.
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公开(公告)号:US11505470B2
公开(公告)日:2022-11-22
申请号:US17051904
申请日:2019-05-03
Inventor: George Christou , Bradley Keith Russell-Webster
Abstract: Described herein are compositions and methods relating to molecular cerium-oxide nanoclusters. Described herein are methods of producing cerium-oxide nanoclusters. Described herein are cerium-oxide nanoclusters. Further described herein are cerium-oxide nanoclusters produced by methods as described herein. Methods as described herein can comprise providing a first cerium source, an organic acid, and a solvent; and mixing the cerium source and the organic acid in the presence of a solvent to create a reaction mixture at a temperature and a pressure for a period of time to create a composition of molecular cerium-oxide nanoclusters containing a plurality of molecular cerium-oxide nanoclusters.
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公开(公告)号:US20220340612A1
公开(公告)日:2022-10-27
申请号:US17761109
申请日:2020-09-17
Inventor: Zhongwu Guo , Qingjiang Li
IPC: C07H15/10
Abstract: Provided are methods of synthesizing glycolipids. The methods combine chemical and enzymatic transformations to rapidly provide diverse natural and functionalized glycolipids in a high convergent matter. Stepwise enzymatic elongation of a carbohydrate chain of a common glycolipid precursor, compound (1), provides glycan intermediates of Formula (II), using sugar-nucleotides as glycosyl donors and glycosyltransferases as enzymes. Also provided are glycan intermediates of Formula (II) and alkene intermediates of Formula (IV) and methods of preparing same.
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公开(公告)号:US20220331405A1
公开(公告)日:2022-10-20
申请号:US17636715
申请日:2020-08-28
Inventor: Bryan D. JAMES , Josephine ALLEN
IPC: A61K38/39 , C12N15/115
Abstract: Disclosed herein is the use of DNA aptamer assemblies of varying DNA length, structure, and sequence to both bind to collagen and other proteins, to then act as a biocompatible, degradable, reversible, or permanent 3D crosslinkers between proteins, and to service as a biologically functional material when using the appropriate aptamer sequence. Therefore, disclosed herein are compositions comprising collagen fibers crosslinked with DNA aptamers. Also disclosed are devices and implants made from or coated with collagen fibers crosslinked with DNA aptamers. Also disclosed are methods of making collagen fibers. Also disclosed are kits for producing collagen fibers. Also disclosed herein are compositions DNA aptamers in a collagen fiber matrix that stabilizes the DNA aptamer.
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