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公开(公告)号：US10751440B2
公开(公告)日：2020-08-25
申请号：US16112741
申请日：2018-08-26
IPC分类号： A61K38/17 , A61K45/06 , A61K9/00 , C07K14/46 , A61L12/14 , A61P27/02 , A61K38/04 , B29D11/00 , G02B1/04
摘要： Provided herein are synthetic antibacterial peptides that have a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for stimulating wound healing via the synthetic antibacterial peptides and for forming an antimicrobial coating on contact lenses. In addition a device is provided that has a surface with a coating of the synthetic antibacterial peptides.
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公开(公告)号：US20200150312A1
公开(公告)日：2020-05-14
申请号：US16747871
申请日：2020-01-21
发明人： Wei-Chuan Shih , Yu-Lung Sung
摘要： A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate.
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公开(公告)号：US10607753B2
公开(公告)日：2020-03-31
申请号：US15384486
申请日：2016-12-20
发明人： Venkat Selvamanickam , Yimin Chen
摘要： A method and composition for doped HTS tapes having directional flux pinning and critical current.
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公开(公告)号：US20200030303A1
公开(公告)日：2020-01-30
申请号：US16496503
申请日：2018-03-29
IPC分类号： A61K31/444
摘要： Identified compounds demonstrate protein kinase inhibitory activity and inhibition of dependent cell signaling pathways, such as NOD2 cell signaling. More specifically, the compounds are demonstrated to inhibit receptor interacting kinase 2 (RIPK2) and/or Activin-like kinase 2 (ALK2). Compounds that are either dual RIPK2/ALK2 inhibitors or that preferentially inhibit RIPK2 or ALK2 could provide therapeutic benefit.
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公开(公告)号：US10522875B2
公开(公告)日：2019-12-31
申请号：US15571324
申请日：2016-05-20
发明人： Yan Yao , Yanliang Liang , Saman Gheytani , Yan Jing
摘要： An improved lead acid battery (LAB) battery may provide high charge acceptance and may be suitable for a wide range of applications, including a variety of new applications. The new battery can sustain 67% of the maximum capacity even at a very high charging rate of IOC. This battery may decrease the use of lead in comparison to prior lead acid battery designs by up to 50%.
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公开(公告)号：US10409138B2
公开(公告)日：2019-09-10
申请号：US16357640
申请日：2019-03-19
发明人： P. Shiv Halasyamani , Hongwei Yu
摘要： Disclosed is a nonlinear optical (NLO) material for use in deep-UV applications, and methods of fabrication thereof. The NLO is fabricated from a plurality of components according to the formula AqByCz and a crystallographic non-centrosymmetric (NCS) structure. The NLO material may be fabricated as a polycrystalline or a single crystal material. In an embodiment, the material may be according to a formula Ba3ZnB5PO14.
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67.发明申请公开(公告)号：US20190263661A1
公开(公告)日：2019-08-29
申请号：US16310533
申请日：2017-06-27
发明人： Anima B. BOSE , Wei LI
IPC分类号： C01B25/42 , C01G19/02 , H01M8/1016
摘要： A method of restoring the proton conductivity of a sintered pyrophosphate membrane of intermediate temperature fuel cells (IT-FCs) by introducing phosphoric acid into the sintered SnP2O7 membrane to react with the degraded SnP2O7 species and thus restore the membrane pyrophosphate and proton conductivity. Such cells operate with low external humidification, and the active area of the cells may be fabricated up to 100 cm2 in size.
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公开(公告)号：US20190239785A1
公开(公告)日：2019-08-08
申请号：US16381873
申请日：2019-04-11
发明人： Luca POLLONINI , Clifford C. DACSO
IPC分类号： A61B5/1455 , A61B5/11 , A61B5/145
CPC分类号： A61B5/14551 , A61B5/024 , A61B5/1107 , A61B5/1112 , A61B5/1118 , A61B5/1123 , A61B5/14546 , A61B5/6831 , A61B5/6898 , A61B5/7225
摘要： The present disclosure generally relates to methods of using near infra-red radiation, such as from a near infra-red spectroscopy device, to monitor physical activity in a person. In one aspect, a method of measuring physiological parameters is provided. The method further includes determining a NIRS-derived measure of a tissue of a person using near infra-red spectroscopy over a time period, associating the NIRS-derived measure to the time period to determine a function-related change, and associating the function-related change to a biomechanical function.
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公开(公告)号：US10328261B2
公开(公告)日：2019-06-25
申请号：US15398491
申请日：2017-01-04
发明人： Adrian Glasser
摘要： Embodiments described herein generally relate to devices and methods for stimulation or recording of accommodation of an eye. Accommodation of an eye naturally occurs through contraction of the ciliary muscle. Embodiments described herein can deliver electrostimulation to the ciliary muscle through a pair of electrodes which deliver power over an area of the sclera which is both positioned above and over an area which is substantially equivalent to the surface area of the ciliary muscle. In further embodiments, electrical impulses produced by the ciliary muscle can be received by one or more electrodes positioned proximate the ciliary muscle. Thus, by embodiments described herein, accommodation of the eye can be reproducibly achieved by external stimulation of the ciliary muscle or measured based on electrical impulses generated by or in conjunction with the ciliary muscle.
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公开(公告)号：US20190188851A1
公开(公告)日：2019-06-20
申请号：US16278946
申请日：2019-02-19
申请人： George Zouridakis
发明人： George Zouridakis
摘要： Provided herein are digital-implemented methods for performing simultaneous analyses on an object on the skin of an animal body, for example, a human, to classify the object as a skin cancer, an ulcer or neither. The analyses are performed simultaneously on a hand-held imaging device.
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