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公开(公告)号：US10342771B2
公开(公告)日：2019-07-09
申请号：US15968858
申请日：2018-05-02
Inventor： Donald W. Miller , Jonathan L. Vennerstrom , Mark C. Faulkner
IPC: A23L2/52 , A61K9/00 , A23K20/10 , A23K50/10 , A23L33/10 , A23P10/40 , A23K20/105 , A23K20/142 , A23L33/175 , A61K31/185 , A61K31/195 , A61K31/198 , A61K31/661
Abstract: The present invention is directed to an oral supplement including creatine hydrochloride, which has an aqueous solubility that is at least 15 times greater than creatine monohydrate, where the oral supplement drives significant improvements in muscle development and recovery due to its enhanced bio-availability, while causing fewer negative side effects compared to previous forms of creatine.
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公开(公告)号：US10335024B2
公开(公告)日：2019-07-02
申请号：US15018530
申请日：2016-02-08
Inventor： Mark Rentschler , Shane Farritor
IPC: A61M29/00 , A61B1/313 , A61B17/02 , A61B34/00 , A61B17/34 , A61B1/32 , A61B17/00 , A61B34/30 , A61B90/50
Abstract: The various embodiments disclosed herein relate to procedural space maintenance devices, medical device positioning devices, and devices that provide both procedural space maintenance and device positioning. Further embodiments relate to medical device insertion and/or retraction devices.
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公开(公告)号：US20190192741A1
公开(公告)日：2019-06-27
申请号：US16307711
申请日：2017-07-21
Inventor： Jingwei Xie , Shixuan Chen , Bernard Timothy Baxter
IPC: A61L27/54 , A61K31/7068 , A61L27/18
CPC classification number: A61L27/54 , A61K9/0092 , A61K9/70 , A61K31/7068 , A61L27/18 , A61L2300/406 , A61L2300/41 , A61L2300/416 , A61L2400/12 , C08L67/04
Abstract: Nanofiber structures are provided along with methods of production and methods of use.
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公开(公告)号：US20190153539A1
公开(公告)日：2019-05-23
申请号：US16094965
申请日：2017-04-20
Applicant: The United States of America, as represented by the secretary, Dep. of Health and Human Service , British Columbia Cancer Agency Branch , Julius-Maximilians - University of Würzburg , Oregon Health & Science University , Hospital Clinic de Barcelona , Universitat de Barcelona , Oslo University Hospital HF , Board of Regents of the University of Nebraska , The Cleveland Clinic Foundation , Mayo Foundation for Medical Education and Research
Inventor： Louis M. Staudt , David William Scott , George W. Wright , Andreas Rosenwald , Pau Abrisqueta , Rita Braziel , Elias Campo Guerri , Wing C. Chan , Joseph M. Connors , Jan Delabie , Diego Villa , Kai Fu , Randy D. Gascoyne , Timothy Greiner , Elaine S. Jaffe , Pedro Jares , Anja Mottok , German Ott , Lisa M. Rimsza , Graham Slack , Dennis Weisenburger , Erlend B. Smeland , James Robert Cook
IPC: C12Q1/6886
Abstract: The present invention provides methods of determining a survival predictor score of a subject having mantle cell lymphoma (MCL). The present invention also provides methods of predicting the survival outcome of a subject having MCL and provides methods of selecting a treatment for a subject having MCL.
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公开(公告)号：US20190117735A1
公开(公告)日：2019-04-25
申请号：US16092561
申请日：2017-04-24
Inventor： Howard E. Gendelman , R. Lee Mosley , Gary Suizdak , Erica Forsberg
Abstract: The present invention provides novel biomarkers for regulatory T cells (Treg) function and Parkinson's disease.
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Patent Agency Ranking
公开(公告)号：US20190083408A1
公开(公告)日：2019-03-21
申请号：US16209300
申请日：2018-12-04
Inventor： Joseph A. Vetro , Sam D. Sanderson
Abstract: Controlled-release formulations of carboxy-terminal C5a analogs (such as sustained-release formulations of the analogs), and their use in methods for treating and preventing an infection or a disease such as cancer, for directly killing microorganisms, for vaccine preparation, for inducing an immune response and for targeting antigen-presenting cells and other cells bearing a C5a receptor, are provided.
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公开(公告)号：US20180313826A1
公开(公告)日：2018-11-01
申请号：US15900680
申请日：2018-02-20
Inventor： Geoffrey M. THIELE , Daniel R. ANDERSON , Michael J. DURYEE
IPC: G01N33/53 , A61K49/00 , G01N33/564
Abstract: In various embodiments methods are provided for identifying a mammal having an elevated risk for an adverse cardiac event (e.g. an MI) and/or determining the prognosis for the mammal. In certain embodiments the methods comprise determining, or causing to be determined, the presence and/or level of antibodies that bind a malondialdehyde-acetaldheyde adduct (MAA adduct) in a biological sample from the mammal, where an elevated level of anti-MAA adduct antibodies, as compared to the level found in a normal healthy mammal is an indicator that that said mammal has one or more atherosclerotic lesions and/or is at elevated risk for a myocardial infarction.
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公开(公告)号：US20180305713A1
公开(公告)日：2018-10-25
申请号：US16027066
申请日：2018-07-03
Inventor： Blair D. Siegfried , Kenneth E. Narva , Kanika Arora , Sarah E. Worden , Chitvan Khajuria , Elane Fishilevich , Nicholas P. Storer , Meghan Frey , Ronda L. Hamm , Ana Velez
IPC: C12N15/82 , A01N57/16 , A01N63/02 , C12N15/113
CPC classification number: C12N15/8286 , A01N57/16 , A01N63/02 , C07K2319/21 , C12N15/113 , C12N15/8218 , C12N2310/14 , Y02A40/162
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.
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公开(公告)号：US20180305694A1
公开(公告)日：2018-10-25
申请号：US16027106
申请日：2018-07-03
Inventor： Blair D. Siegfried , Kenneth E. Narva , Kanika Arora , Sarah E. Worden , Chitvan Khajuria , Elane Fishilevich , Nicholas P. Storer , Meghan Frey , Ronda L. Hamm , Ana Velez
IPC: C12N15/113 , C12N15/82 , A01N37/46 , A01N57/16
CPC classification number: C12N15/113 , A01N37/46 , A01N57/16 , C12N15/8218 , C12N15/8286 , C12N2310/14 , Y02A40/162
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.
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公开(公告)号：US10080617B2
公开(公告)日：2018-09-25
申请号：US15354778
申请日：2016-11-17
Inventor： Hani Haider , Ibrahim Al-Shawi , Osvaldo Andres Barrera
CPC classification number: A61B34/20 , A61B1/3132 , A61B5/00 , A61B5/061 , A61B5/1076 , A61B17/142 , A61B17/1703 , A61B34/37 , A61B34/76 , A61B2034/102 , A61B2034/2057 , A61B2034/2065 , A61B2090/061 , A61B2090/064 , A61B2090/3983 , G06K2209/057 , G06T2207/30004
Abstract: A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer aided surgery and the devices used during such procedures. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled using the OTT device. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure including the rate of and type of data processed depending upon a CAS mode.
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