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公开(公告)号：US20050098658A1
公开(公告)日：2005-05-12
申请号：US10706709
申请日：2003-11-12
申请人： David Burke
发明人： David Burke
CPC分类号： B05B1/1654
摘要： The spray head of the spray head assembly of the pre-rinse assembly has five different positions to deliver five different types of water patterns.The spray head has internal ports that communicate with openings that have spouts or an aperturedplate to delivera full full stream, a jet stream or a mist. In addition, the spray head has ports that communicate with two separate internal chambers that, in turn, communicate with a pair of concentric rings of openings to deliver a center spray pattern or a shower spray pattern of water. The spray head can be used to wash or rinse utensils that need cleaning, to scour adhered food particles from utensils using a jet spray, and to apply a mist or shower pattern to foods that need refreshing or cleaning.
摘要翻译： 预漂洗组件的喷头组件的喷头具有五个不同的位置以输送五种不同类型的水图案。喷头具有与具有喷口或孔径的开口连通的内部端口，以输送完整的全流， 喷流或雾气。 此外，喷头具有与两个分开的内部室连通的端口，该两个独立的内部室又与一对同心的开口环连通，以传递中心喷雾图案或淋浴喷雾图案的水。 喷头可用于洗涤或冲洗需要清洁的器具，使用喷射式喷雾器从器具中冲洗残留的食物颗粒，并对需要刷新或清洁的食物施加雾状或淋浴型态。
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62.发明授权公开(公告)号：US06599880B1
公开(公告)日：2003-07-29
申请号：US09579403
申请日：2000-05-25
申请人： Arnold Horwitz , Stephen F. Carroll , David Burke
发明人： Arnold Horwitz , Stephen F. Carroll , David Burke
IPC分类号： A61K3800
CPC分类号： A61K38/17 , C07K14/4742
摘要： Novel BPI deletion analogs are provided that consist of amino acid residues 10 through 193 of mature human BPI wherein the cysteine residue at BPI amino acid position 132 is replaced by another amino acid. Fusion proteins comprising these analogs are also provided, as are polynucleotides encoding these products, materials and methods for their recombinant production, compositions and medicaments of these products, and therapeutic uses for these products.
摘要翻译： 提供了由成熟人BPI的氨基酸残基10至193组成的新型BPI缺失类似物，其中BPI氨基酸位置132处的半胱氨酸残基被另一个氨基酸替代。 还提供了包含这些类似物的融合蛋白，编码这些产物的多核苷酸，其重组生产的材料和方法，这些产品的组合物和药物以及这些产品的治疗用途。
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公开(公告)号：US06460935B1
公开(公告)日：2002-10-08
申请号：US09445049
申请日：2000-02-23
申请人： Elizabeth Rees , Alan George Smithson , David Burke , Andrew John Downie , Carlo Martellini , Richard Harman , David Blackadder
发明人： Elizabeth Rees , Alan George Smithson , David Burke , Andrew John Downie , Carlo Martellini , Richard Harman , David Blackadder
IPC分类号： A47C3100
CPC分类号： B60R22/1952
摘要： A buckle pretensioner for a vehicle safety restraint comprising a buckle head (1) for receiving a buckle tongue to secure safety restraint webbing about a vehicle occupant in a three-point belt system; a cable (2) connected to the buckle head (1); and device (7) for rapidly withdrawing the cable in a belt tightening direction, the withdrawing device (7) comprising a force reservoir (8), and driving mechanism (6), and being of a compact construction through the use of set-up gearing (3,4) to magnify linear movement produced by the force reservoir (8) which may be a pyrotechnic gas generator or a spring. The driving mechanism (8) may be a piston-cylinder (6,8) or a rack and pinion. The gearing may comprise a pulley arrangement (3,4). Alternatively a roots motor or a gear pump could be used.
摘要翻译： 一种用于车辆安全限制器的带扣预紧器，包括用于接收带扣舌片的带扣头（1），以在三点带系统中固定关于车辆乘员的安全约束带; 连接到所述带扣头（1）的电缆（2）; 以及用于在带紧固方向上快速拉出电缆的装置（7），所述抽出装置（7）包括力储存器（8）和驱动机构（6），并且通过使用设置而具有紧凑的结构 传动（3,4）以放大由力储存器（8）产生的线性运动，其可以是烟火气体发生器或弹簧。 驱动机构（8）可以是活塞缸（6,8）或齿条和小齿轮。 传动装置可以包括滑轮装置（3,4）。 或者可以使用根马达或齿轮泵。
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公开(公告)号：US6088890A
公开(公告)日：2000-07-18
申请号：US52599
申请日：1998-03-31
CPC分类号： A44B11/2523 , Y10T24/45623 , Y10T24/45665
摘要： A buckle for a vehicle safety restraint for use with a pretensioner has an actuating button for operating a latch for the tongue of the safety restraint. The button is connected via pulleys to a counterbalancing mass. When the pretensioner is operated and the buckle is retracted, the inertia of the mass counteracts the inertia of the button. Thus the button is prevented from moving in relation to the buckle in a direction which would tend to unlatch the tongue of the safety restraint.
摘要翻译： 用于与预张紧器一起使用的车辆安全限制器的带扣具有用于操作安全限制器的舌头的闩锁的致动按钮。 按钮通过滑轮连接到平衡质量块。 当预紧器被操作并且扣环缩回时，质量的惯性抵消了按钮的惯性。 因此，防止按钮相对于带扣沿着倾向于解除安全限制的舌头的方向移动。
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公开(公告)号：US6087126A
公开(公告)日：2000-07-11
申请号：US336402
申请日：1999-06-18
申请人： Arnold Horwitz , Stephen F. Carroll , David Burke
发明人： Arnold Horwitz , Stephen F. Carroll , David Burke
IPC分类号： C12N15/09 , A01N37/18 , A61K38/00 , A61K38/16 , A61P31/04 , C07H21/04 , C07K14/00 , C07K14/47 , C12N5/00 , C12N5/10 , C12N9/48 , C12N15/31 , C12N15/74 , C12P21/02 , C12P21/06 , C12R1/91 , C12N5/06 , C12N15/00
CPC分类号： A61K38/17 , C07K14/4742
摘要： Novel BPI deletion analogs are provided that consist of amino acid residues 10 through 193 of mature human BPI wherein the cysteine residue at BPI amino acid position 132 is replaced by another amino acid. Fusion proteins comprising these analogs are also provided, as are polynucleotides encoding these products, materials and methods for their recombinant production, compositions and medicaments of these products, and therapeutic uses for these products.
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66.发明授权Stable bactericidal/permeability-increasing protein products and pharmaceutical compositions containing the same 失效稳定的杀菌/增加渗透性蛋白质产物和含有其的药物组合物
公开(公告)号：US5674834A
公开(公告)日：1997-10-07
申请号：US430417
申请日：1995-04-28
申请人： Georgia Theofan , Arnold Horwitz , David Burke , Manik Baltaian , Lynn Grinna
发明人： Georgia Theofan , Arnold Horwitz , David Burke , Manik Baltaian , Lynn Grinna
IPC分类号： C12N15/09 , A61K38/00 , A61P7/02 , A61P7/06 , A61P9/02 , A61P11/00 , A61P13/12 , A61P31/00 , A61P31/04 , A61P39/02 , C07H21/04 , C07K14/47 , C07K14/52 , C07K16/00 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/02 , C12N5/10 , C12N15/12 , C12N15/85 , C12P21/02 , C12R1/91 , A61K38/17
CPC分类号： C07K19/00 , C07K14/4742 , C12N15/85 , A61K38/00 , C07K2319/00 , C12N2830/00 , C12N2830/15 , C12N2830/30 , C12N2830/60 , C12N2830/85 , C12N2840/44
摘要： Disclosed are novel bactericidal/permeability-increasing (BPI) protein products wherein cysteine residue number 132 or 135 is replaced by another amino acid residue, preferably an alanine or serine residue and/or wherein the leucine residue at position 193 is the carboxy terminal residue. Also disclosed are DNA sequences encoding methods for the production of the same in appropriate host cells, and stable homogeneous pharmaceutical compositions containing the analogs suitable for use treatment of gram negative bacterial infection and its sequelae.
摘要翻译： 公开了新的杀菌/渗透性增加（BPI）蛋白产物，其中半胱氨酸残基132或135被另一个氨基酸残基，优选丙氨酸或丝氨酸残基替代，和/或其中第193位的亮氨酸残基是羧基末端残基。 还公开了编码在合适的宿主细胞中制备其的方法的DNA序列，以及含有适合用于治疗革兰氏阴性细菌感染及其后遗症的类似物的稳定的均匀药物组合物。
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公开(公告)号：US5348111A
公开(公告)日：1994-09-20
申请号：US169742
申请日：1993-12-17
申请人： David A. Williams , Peter G. Wright , David Burke
发明人： David A. Williams , Peter G. Wright , David Burke
IPC分类号： B62D6/00 , B62D7/14 , B62D7/15 , B62D101/00 , B62D111/00 , B62D113/00 , B62D137/00
摘要： A wheeled vehicle steering system comprising an adjustable steering input device, a device for generating a first electrical signal proportional to demanded input of the steering input device, a device for steering a vehicle wheel in response to the first electrical signal, a sensing device for detecting the response of the vehicle, a device for producing a second electrical signal proportional to the detected response, an input filter for filtering the first electrical signal, a comparator device for comparing the filtered first electrical signal and the second electrical signal and producing a different signal from comparison of the first and second electrical signals, a device for steering a vehicle wheel in response to the difference signal.
摘要翻译： 一种轮式车辆转向系统，包括可调转向输入装置，用于产生与所述转向输入装置的所需输入成比例的第一电信号的装置，用于响应于所述第一电信号转向车轮的装置，用于检测 车辆的响应，用于产生与检测到的响应成比例的第二电信号的装置，用于对第一电信号进行滤波的输入滤波器，用于比较滤波的第一电信号和第二电信号并产生不同信号的比较器装置 根据所述第一和第二电信号的比较，响应于所述差分信号转向车轮的装置。
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公开(公告)号：US5341546A
公开(公告)日：1994-08-30
申请号：US26335
申请日：1993-03-04
申请人： David Burke
发明人： David Burke
CPC分类号： A44B11/2523 , Y10T24/45665 , Y10T24/45686
摘要： A vehicle seat belt buckle mechanism designed for use with belt pretensioning means and being rendered immune to the effects of rapid buckle deceleration following pretensioning action the mechanism having a resiliently movable plate 82 carried by the buckle release button, the resilience being effectively much lighter than release button return springs 49c so that although the plate 82 normally has no effect, in the event of pretensioning action, it slides into an abutting position in the mechanism to inhibit subsequent spurious release resulting from button movement in a crash situation.
摘要翻译： 一种车辆安全带扣机构，设计用于皮带预张紧装置，并且在预张紧作用后免受快速扣环减速的影响，该机构具有由扣环释放按钮承载的弹性可移动板82，弹性比释放有效地轻得多 按钮复位弹簧49c，使得虽然板82通常没有效果，但是在预张紧作用的情况下，它滑动到机构中的邻接位置，以防止在碰撞情况下按钮移动导致的随后的假释放。
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公开(公告)号：US20210257082A1
公开(公告)日：2021-08-19
申请号：US17308961
申请日：2021-05-05
申请人： David Burke , Dan LeBlanc
发明人： David Burke , Dan LeBlanc
摘要： Techniques are provided which may allow meaningful social engagements to be measured, tracked, and enhanced to allow for enhanced care for each individual receiving care in a facility or home. A combination of type, frequency, proximity, and duration, plus key profile traits may factor into an overall number to rate meaningfulness of social engagements for each individual.
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公开(公告)号：US20120039483A1
公开(公告)日：2012-02-16
申请号：US13026958
申请日：2011-02-14
申请人： David BURKE , Kirk LOMBARDO , Christopher KING
发明人： David BURKE , Kirk LOMBARDO , Christopher KING
CPC分类号： H04R5/023
摘要： A audio system for skateboards comprising an audio module and speakers mounted to the bottom side of a skateboard. The audio module is battery-operated and has a Bluetooth receiver and a stereo amplifier. The speakers face downwards. While the rider is traveling on the skateboard, the sound from the speakers bounces back from the road's surface so that the rider may enjoy music in safe manner without loss of maneuverability.
摘要翻译： 一种用于滑板的音频系统，包括安装在滑板底部的音频模块和扬声器。 音频模块是电池供电的，并具有蓝牙接收器和立体声放大器。 扬声器朝下。 当骑手在滑板上旅行时，来自扬声器的声音从道路表面反弹，使得骑手可以安全地享受音乐而不损失机动性。
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