公开(公告)号：US08958940B2

公开(公告)日：2015-02-17

申请号：US13241347

申请日：2011-09-23

申请人： Hiroaki Kawasaki

发明人： Hiroaki Kawasaki

IPC分类号： G06F7/00 ,  G01G19/08 ,  B60C23/06

CPC分类号： G01G19/086 ,  B60C23/062

摘要： A vehicle mass estimation apparatus includes a wheel rotation speed information detection device configured to detect rotation speed information regarding the respective wheels of the vehicle; a frequency characteristic estimation device configured to calculate wheel acceleration information based on the rotation speed information of the wheels to estimate a frequency characteristic of the wheel acceleration information; and a vehicle mass estimation device configured to estimate a vehicle mass based on the estimated frequency characteristic. The frequency characteristic estimation device calculates an integrated value of frequency gain magnitudes of the respective frequency domains of front wheels and rear wheels of the vehicle, and the vehicle mass estimation device estimates the vehicle mass based on the ratio among the respective integrated values of the front wheels and rear wheels and a relation calculated in advance between the ratio and the vehicle mass.

摘要翻译： 车辆质量估计装置包括车轮转速信息检测装置，其被配置为检测关于车辆的各车轮的转速信息; 频率特性估计装置，被配置为基于所述车轮的转速信息来计算车轮加速度信息，以估计所述车轮加速度信息的频率特性; 以及车辆质量估计装置，其被配置为基于所估计的频率特性来估计车辆质量。 频率特性估计装置计算车辆的前轮和后轮的各个频域的频率增益量的积分值，车辆质量估计装置基于前方的各个积分值之间的比率来估计车辆质量 车轮和后轮以及在比率和车辆质量之间预先计算的关系。

公开(公告)号：US08299909B2

公开(公告)日：2012-10-30

申请号：US12497283

申请日：2009-07-02

申请人： Hajime Fujita ,  Hiroaki Kawasaki

发明人： Hajime Fujita ,  Hiroaki Kawasaki

IPC分类号： G08B21/00

CPC分类号： B60C23/061 ,  B60C23/062

摘要： An apparatus for detecting a decrease in a tire air pressure includes; a rotation velocity information detection means for regularly detecting tire rotation velocity information regarding the respective wheels of a vehicle; a resonance frequency estimation means for estimating a resonance frequency of the rotation velocity information based on the rotation velocity information obtained by the rotation velocity information detection means; and a determination means for determining, based on the estimated resonance frequency, a decrease in the tire air pressure. The apparatus includes a data rejecting means for rejecting data of rotation velocity information hindering the estimation of the resonance frequency.

摘要翻译： 用于检测轮胎气压降低的装置包括： 旋转速度信息检测装置，用于定期检测关于车辆的各个车轮的轮胎转速信息; 谐振频率估计装置，用于基于由所述旋转速度信息检测装置获得的旋转速度信息来估计所述旋转速度信息的共振频率; 以及确定装置，用于基于所估计的共振频率来确定轮胎空气压力的降低。 该装置包括用于拒绝阻碍谐振频率的估计的旋转速度信息的数据的数据拒绝装置。

公开(公告)号：US08159102B2

公开(公告)日：2012-04-17

申请号：US12813166

申请日：2010-06-10

申请人： Yuichi Yoshikawa ,  Hiroaki Kawasaki ,  Kenji Sugiura ,  Hiroshi Ueda ,  Hiroki Asai

发明人： Yuichi Yoshikawa ,  Hiroaki Kawasaki ,  Kenji Sugiura ,  Hiroshi Ueda ,  Hiroki Asai

IPC分类号： H02K7/00

CPC分类号： H02K11/225 ,  H02K1/146

摘要： A rotor 14 is rotatably disposed around a stator 13 that is provided with a plurality of magnetic poles 13a. The inner circumferential face of a rotor frame 14b of the rotor is provided with a magnet 15 magnetized to have alternately opposite polarities in a direction opposing the stator, and magnetized to have alternately opposite polarities in a direction opposing a substrate. The outer circumferential ends of the magnetic poles of the stator are provided with a first extended portion 13c that extends from a magnetic pole base 13d to a substrate 11 side, and a second extended portion 13b that extends from the magnetic pole base to a side opposite the substrate side. A face of the substrate opposing the rotor is provided with a FG pattern 19. When a distance between an end of the rotor frame on the substrate side and the substrate is taken as A, a distance between an end of the first extended portion on the substrate side and the substrate is taken as B, and a distance between the end of the first extended portion on the substrate side and the magnet is taken as G, B≦A≦B+G is satisfied. Accordingly, it is possible to improve the precision in detecting the rotational speed by reducing noise superimposed on the FG signal, while securing a high driving efficiency.

摘要翻译： 转子14围绕设置有多个磁极13a的定子13可旋转地设置。 转子的转子架14b的内周面设置有磁体15，该磁体被磁化成与定子相反的方向具有相反的极性，并且在与基板相对的方向上被磁化成具有相反的极性。 定子的磁极的外周端设置有从磁极基部13d延伸到基板11侧的第一延伸部13c和从磁极基部延伸到相反侧的第二延伸部13b 基板侧。 与转子相对的基板的表面设置有FG图案19.当基板侧的转子框架的端部与基板之间的距离取为A时，第一延伸部分的端部之间的距离 将基板侧和基板取为B，将基板侧的第一延伸部的端部与磁铁的距离设为G，B＆nlE;满足A＆lt; NlE; B + G。 因此，在确保高驱动效率的同时，通过降低叠加在FG信号上的噪音来提高检测转速的精度。

公开(公告)号：US08159097B2

公开(公告)日：2012-04-17

申请号：US12813258

申请日：2010-06-10

申请人： Yuichi Yoshikawa ,  Hiroaki Kawasaki ,  Kenji Sugiura ,  Hiroshi Ueda ,  Hiroki Asai

发明人： Yuichi Yoshikawa ,  Hiroaki Kawasaki ,  Kenji Sugiura ,  Hiroshi Ueda ,  Hiroki Asai

IPC分类号： H02K7/00

CPC分类号： H02K29/03 ,  H02K1/146 ,  H02K1/2786

摘要： A rotor 14 is rotatably disposed around a stator 13 that is provided with a plurality of magnetic poles 13a. The inner circumferential face of the rotor is provided with a magnet 15 on whose face opposing the stator main magnetization is performed, and on whose face opposing the substrate FG magnetization is performed. The outer circumferential ends of the magnetic poles of the stator are provided with extended portions 13b and 13c that vertically extend from the magnetic pole base 13d. A face of the substrate opposing the rotor is provided with a FG pattern 19 opposing the magnet 15. The FG pattern is disposed on an outer side in a radial direction of the outer circumferential face of the stator. When an angle formed by a straight line connecting a central position in the radial direction of the magnet and a central position in the radial direction of the FG pattern with respect to a central axis of a driving shaft is taken as θ, and an angle formed by a direction of the FG magnetization with respect to the central axis of the driving shaft is taken as A, 0 degree

摘要翻译： 转子14围绕设置有多个磁极13a的定子13可旋转地设置。 转子的内周面设置有磁铁15，在磁体15的与定子主磁化相反的方向上进行磁体15，并且在其表面与基板FG的磁化相反的方向被执行。 定子的磁极的外周端设置有从磁极基座13d垂直延伸的延伸部分13b和13c。 与转子相对的基板的表面设置有与磁体15相对的FG图案19.GV图案设置在定子的外周面的径向外侧。 当将连接磁体径向中心位置的直线和FG图案径向方向上的中心位置相对于驱动轴的中心轴线形成的角度取为角度时， 由相对于驱动轴的中心轴线的FG磁化方向形成的A为0度

公开(公告)号：US20100256416A1

公开(公告)日：2010-10-07

申请号：US12734661

申请日：2008-11-07

申请人： Hiroaki Kawasaki ,  Katsuji Maehara ,  Tadashi Moroshima

发明人： Hiroaki Kawasaki ,  Katsuji Maehara ,  Tadashi Moroshima

IPC分类号： C07C229/26

CPC分类号： C07C273/1827 ,  C07C275/16

摘要： The present invention relates to a process for producing an N-carbamoyl-tert-leucine, characterized in mixing tert-leucine with an isocyanic acid compound while a pH of the mixture is kept at not less than 8.0 and not more than 13.5, wherein an amount of the isocyanic acid compound is not less than 0.9 times by mole and not more than 1.1 times by mole relative to an amount of the tert-leucine. According to the present invention, it becomes possible to easily produce an N-carbamoyl-tert-leucine with high efficiency, while the generation of by-products such as a dipeptide-like compound and a urea compound is prevented.

摘要翻译： 本发明涉及一种N-氨基甲酰基 - 叔 - 亮氨酸的制备方法，其特征在于，将所述混合物的pH值保持在8.0以上且13.5以下的条件下，将叔亮氨酸与异氰酸化合物混合， 异氰酸化合物的量相对于叔亮氨酸的量为0.9倍摩尔以上1.1倍以下。 根据本发明，可以高效率地容易地制造N-氨基甲酰基 - 叔 - 亮氨酸，同时防止二肽类化合物和尿素化合物等副产物的产生。

公开(公告)号：US20100225463A1

公开(公告)日：2010-09-09

申请号：US12652243

申请日：2010-01-05

申请人： Hajime Fujita ,  Hiroaki Kawasaki

发明人： Hajime Fujita ,  Hiroaki Kawasaki

IPC分类号： B60C23/00 ,  B60C23/02

CPC分类号： B60C23/061 ,  B60C23/062

摘要： An apparatus for detecting a tire having a decreased pressure based on resonance frequency of tires attached to respective wheels of a vehicle. The apparatus includes a storage means for storing information regarding a distribution of resonance frequencies respectively corresponding to a plurality of air pressure statuses, an initialization means for estimating a frequency characteristic of the rotation speed information or the rotation acceleration information, a frequency estimation means for estimating a frequency characteristic of the rotation speed information or the rotation acceleration information of a running vehicle, and a Bayesian estimation means for subjecting a tire pressure status at a certain time to a Bayesian estimation based on the resonance frequency during the initialization, a resonance frequency at the certain time obtained from the frequency estimation means, and distribution-related information stored in the storage means.

摘要翻译： 一种用于基于车辆的各车轮附接的轮胎的共振频率来检测具有减小的压力的轮胎的装置。 该装置包括存储装置，用于存储关于分别对应于多个气压状态的共振频率分布的信息，用于估计转速信息或旋转加速度信息的频率特性的初始化装置，用于估计 行驶车辆的转速信息或旋转加速度信息的频率特性，以及基于在初始化期间的共振频率对特定时间的轮胎压力状态进行贝叶斯估计的贝叶斯估计装置， 从频率估计装置获得的一定时间，以及存储在存储装置中的分配相关信息。

公开(公告)号：US20060247193A1

公开(公告)日：2006-11-02

申请号：US10544761

申请日：2004-02-10

申请人： Kazunari Taira ,  Hiroaki Kawasaki

发明人： Kazunari Taira ,  Hiroaki Kawasaki

IPC分类号： A61K48/00 ,  C12N15/09

CPC分类号： C12N15/113 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531

摘要： The present invention provides products and methods for modulating expression of a target gene in a cell. One such method includes introducing into the cell a polynucleotide that forms a duplex region with an mRNA transcribed from said target gene, where the duplex region comprises a mammalian miRNA target region. Another such method includes introducing into the cell an siRNA that forms a duplex region with an miRNA, or precursor thereof, where an mRNA transcribed from the target gene comprises a miRNA target region. In certain preferred embodiments, the methods further include measuring expression of the target gene. The methods are particularly useful for modulating ontogenesis, function, differentiation and/or viability of a mammalian cell. As such, the invention also provides methods for controlling ontogenesis of mammal, function of mammalian cell, differentiation of mammalian cell or viability of mammalian cell in the post-transcriptional phase by introducing into the cell a miRNA or a siRNA silencing precursor to the miRNA. The invention additionally provides polynucleotides, including vectors, useful in the method of the instant invention. The provided polynucleotides include a plasmid vector comprising a promoter and a polynucleotide sequence expressing miRNA or precursor to the miRNA. Also included is a plasmid vector comprising a promoter and a nucleotide sequence expressing siRNA silencing precursor to miRNA. In certain preferred embodiments, the mRNA is capable of forming a duplex region with an mRNA transcribed from a mammalian target gene.

摘要翻译： 本发明提供调节细胞中靶基因表达的产物和方法。 一种这样的方法包括向细胞中引入与从所述靶基因转录的mRNA形成双链体区的多核苷酸，其中双链区包含哺乳动物miRNA靶区。 另一种这样的方法包括向细胞中引入与miRNA或其前体形成双链体区的siRNA，其中从靶基因转录的mRNA包含miRNA靶区。 在某些优选实施方案中，所述方法还包括测量靶基因的表达。 该方法对于调节哺乳动物细胞的发生，功能，分化和/或活力特别有用。 因此，本发明还提供了通过将miRNA或siRNA沉默前体引入细胞来控制哺乳动物细胞的发生，哺乳动物细胞的功能，哺乳动物细胞的分化或哺乳动物细胞在转录后阶段的存活力的方法。 本发明另外提供了可用于本发明方法的多核苷酸，包括载体。 所提供的多核苷酸包括质粒载体，其包含启动子和表达miRNA或miRNA前体的多核苷酸序列。 还包括质粒载体，其包含启动子和表达miRNA沉默前体的核苷酸序列。 在某些优选的实施方案中，mRNA能够与从哺乳动物靶基因转录的mRNA形成双链体区域。

公开(公告)号：US06650988B2

公开(公告)日：2003-11-18

申请号：US10270558

申请日：2002-10-16

申请人： Hiroaki Kawasaki ,  Yukio Nakao

发明人： Hiroaki Kawasaki ,  Yukio Nakao

IPC分类号： B60T866

CPC分类号： B60T8/172 ,  B60T2210/12

摘要： A method and an apparatus for judging road surface conditions are disclosed. The method includes the steps of: detecting rotational information of tires; storing the rotational information of the respective tires; calculating a vehicle velocity; calculating an acceleration/deceleration of the vehicle; calculating a slip ratio of left-sided front and rear wheels and right-sided front and rear wheels and a slip ratio of front and rear wheels, respectively; calculating an amount of fluctuation in differences in slip ratios between the right and left wheels; obtaining a linear regression coefficient and a correlation coefficient between the slip ratio of the front and rear wheels and the acceleration/deceleration of the vehicle; and setting a threshold for judging road surface conditions. The method and apparatus allow for road surface conditions to be judged accurately.

摘要翻译： 公开了一种用于判断路面条件的方法和装置。 该方法包括以下步骤：检测轮胎的旋转信息; 存储各轮胎的旋转信息; 计算车速; 计算车辆的加速/减速; 计算左右前后轮和右前后轮的滑移率和前后轮的滑移率; 计算左右车轮之间滑移率差异的波动量; 获得前后滑动比与车辆的加速/减速之间的线性回归系数和相关系数; 并设定判断路面条件的阈值。 该方法和装置能够准确地判断路面状况。

公开(公告)号：US06379141B1

公开(公告)日：2002-04-30

申请号：US09379572

申请日：1999-08-24

申请人： Hiroaki Kawasaki ,  Yutaka Hiroshima ,  Yasuo Ishiwata ,  Chisato Akinari

发明人： Hiroaki Kawasaki ,  Yutaka Hiroshima ,  Yasuo Ishiwata ,  Chisato Akinari

IPC分类号： B29C4540

CPC分类号： B29C45/7626 ,  B29C2045/764

摘要： An abnormal mold detector is provided that can previously detect the breakage of a mold tool with an ejector plate. A pressure sensor is attached to the ejector pin of a mold to detect the mold internal pressure. The operation status of the mold is detected by the sensor attached to the mold piece of the mold. An abnormality detector, formed of a CPU, processes the detected pressure signal and the mold working state indicating signal. The abnormality detector sets a reference value D exceeding a normal sticking resistance of the ejector pin. As a material is injected, the mold internal pressure increases during one cycle (A and B) in the molding step. After the molding process, the ejection process is carried out by the ejector pin during the value C. When a sticking resistance exceeding the value D is confirmed during the monitoring operation (FF), the abnormality detector decides that there may be the possibility that an abnormal state occurs in the mold tool. Thus the abnormality detector issues an alarm signal to the operator to halt the operation of the molding machine.

摘要翻译： 提供了一种异常的模具检测器，其可以预先通过喷射板检测模具的破损。 将压力传感器连接到模具的推杆上以检测模具的内部压力。 模具的运行状态由附着在模具的模具上的传感器检测。 由CPU形成的异常检测器处理检测到的压力信号和模具加工状态指示信号。 异常检测器设定超过顶针的正常粘着阻力的基准值D. 当注入材料时，在模制步骤中，模具内部压力在一个循环（A和B）期间增加。 在模制过程之后，在值C期间由顶针执行喷射处理。当在监视操作（FF）期间确认超过值D的粘着阻力时，异常检测器判定可能存在 异型状态发生在模具中。 因此，异常检测器向操作者发出报警信号以停止成型机的操作。

公开(公告)号：US10113148B2

公开(公告)日：2018-10-30

申请号：US14414377

申请日：2013-07-10

申请人： Hiroyuki Abe ,  Hiroaki Kawasaki

发明人： Hiroyuki Abe ,  Hiroaki Kawasaki

IPC分类号： C12N5/0783 ,  C12N5/0786 ,  C07K16/28 ,  C12N5/0784 ,  A61K39/00

摘要： The present invention relates to a method by which cells usable for an immune cell therapy are separated from peripheral blood and grown. The present invention makes it possible to provide immune system cells which are large enough in number to be used in the immune cell therapy.