公开(公告)号：US07927588B2

公开(公告)日：2011-04-19

申请号：US10557998

申请日：2004-06-04

Applicant: Paul James Davis ,  Andrew John Austin

Inventor： Paul James Davis ,  Andrew John Austin

IPC: A61K38/44

CPC classification number: C12N9/0004 ,  A61L15/38 ,  C12N9/96

Abstract: A skin dressing comprises a first dressing component (16) carrying oxidoreductase enzyme in dried condition; and a second dressing component (18) carrying a source of water, such that when the first and second dressing components are placed in fluid communication with each other, water migrates from the second component towards the first comportent and acts to hydrate enzyme carried by the first component, at least at the surface of the first component. The dressing components are kept separate before use, e.g. being sealed in separate sterile, water-impervious packages such as laminated aluminum foil pouches. In use of the dressing, the second dressing component is located on the skin of a human or animal, e.g. over a wound to be treated or on a region of skin to be treated for cosmetic or therapeutic purposes such as for treatment of acne or other skin conditions. The first dressing component is placed on top of the second component in fluid communication therewith. In embodiments comprising only first and second dressing components, the first dressing component is placed in direct contact with the second dressing component. Water from the second component migrates towards the first comportent and acts to hydrate enzyme carried by the first component, at least at points of contact at the interface between the first and second components. Once hydrated, the oxidoreductase enzyme can immediately begin functioning in known manner with beneficial effects.

Abstract translation: 皮肤敷料包括在干燥状态下携带氧化还原酶的第一敷料组分（16） 以及第二敷料组分（18），其携带水源，使得当所述第一和第二敷料组分彼此流体连通时，水从所述第二组分向所述第一压缩物迁移并且用于使由所述第二组分携带的酶水合 第一组分，至少在第一组分的表面。 敷料组分在使用前保持分开，例如 密封在单独的无菌，防水包装如层压铝箔袋中。 在敷料的使用中，第二敷料组分位于人或动物的皮肤上，例如， 在待治疗的伤口上或在用于治疗痤疮或其他皮肤病症的化妆品或治疗目的的皮肤区域上。 第一敷料组分放置在与其流体连通的第二组分的顶部上。 在仅包括第一和第二敷料组分的实施方案中，第一敷料组分被放置成与第二敷料组件直接接触。 至少在第一和第二组分之间的界面处的接触点处，来自第二组分的水向第一组分迁移并用于水合由第一组分携带的酶。 一旦水合，氧化还原酶可以以已知的方式立即开始起作用，具有有益效果。

公开(公告)号：US20110054537A1

公开(公告)日：2011-03-03

申请号：US12550235

申请日：2009-08-28

Applicant: Peter Thomas Miller ,  Charles R. Forton ,  Reginald James Davis

Inventor： Peter Thomas Miller ,  Charles R. Forton ,  Reginald James Davis

IPC: A61B17/88 ,  A61B17/00

CPC classification number: A61B17/88 ,  A61B1/32 ,  A61B17/0218 ,  A61B17/1604 ,  A61B17/1655 ,  A61B17/1659 ,  A61B17/1671 ,  A61B17/1757 ,  A61B17/3472 ,  A61B17/7044 ,  A61B17/885 ,  A61B17/8897 ,  A61B2017/90 ,  A61B2090/036 ,  A61B2090/062 ,  A61F2/4611

Abstract: Embodiments described herein provide tools and methods for spinal fusion procedures. One embodiment of a tool can be a pedicle access tool that performs the functions of targeting needle, cannula, tap and awl. The cannula of the tool can be used to guide various tools and bone graft or fusion promoting material to a surgical site for a spinal fusion procedure, such as a posterolateral procedure. In other embodiments, a k-wire can be used as the guide.

Abstract translation: 本文描述的实施例提供了用于脊柱融合程序的工具和方法。 工具的一个实施例可以是执行瞄准针，插管，抽头和锥的功能的椎弓根进入工具。 该工具的插管可以用于将各种工具和骨移植物或融合促进材料引导到用于脊柱融合程序（例如后外侧手术）的手术部位。 在其他实施例中，可以使用k线作为引导件。

公开(公告)号：US20110040328A1

公开(公告)日：2011-02-17

申请号：US12539468

申请日：2009-08-11

Applicant: Peter Thomas Miller ,  Charles R. Forton ,  Bruce A. Riceman ,  Larry T. Khoo ,  Reginald James Davis ,  Michael Scott Hisey

Inventor： Peter Thomas Miller ,  Charles R. Forton ,  Bruce A. Riceman ,  Larry T. Khoo ,  Reginald James Davis ,  Michael Scott Hisey

IPC: A61B17/70 ,  A61B17/86

CPC classification number: A61B17/7091

Abstract: Embodiments described herein provide systems and methods for vertebral reduction using sleeves detachably coupled to collars of bone fasteners. The reduction can be performed during a minimally invasive procedure for implanting spinal stabilization systems. A sleeve can include internal threads that match threads on the respective collar to form a continuous set of threads. Threads on a closure member can be engaged with the threads on the sleeve and the closure member turned to translate the closure member along the sleeve. The closure member can be used to push a rod relative to the collar to which the sleeve is attached to cause a vertebral body to move.

Abstract translation: 本文描述的实施例提供了使用可拆卸地耦合到骨紧固件的套环的套筒进行脊椎减少的系统和方法。 可以在用于植入脊柱稳定系统的微创手术期间进行减少。 套筒可以包括与相应轴环上的螺纹匹配的内螺纹，以形成连续的一组螺纹。 闭合构件上的螺纹可以与套筒上的螺纹接合，并且闭合构件转动以沿着套筒平移闭合构件。 闭合构件可以用于相对于套筒附接的套环推动杆，以使得椎体移动。

公开(公告)号：US20100121578A1

公开(公告)日：2010-05-13

申请号：US12291528

申请日：2008-11-10

Applicant: Thomas James Davis

Inventor： Thomas James Davis

IPC: G06F19/00 ,  G06F15/00 ,  G01F23/00

CPC classification number: G01N17/02 ,  G06T19/20 ,  G06T2200/24 ,  G06T2219/028 ,  G06T2219/2012 ,  Y10T137/8359

Abstract: A data analysis program operable for displaying at least one representation of a buried pipeline in a geographical area and associated on-pipe current values at various locations along the pipeline. The data analysis program is storable in a memory device and executable by a processor to generate a display on a display device. The data analysis program includes instructions for displaying a digital map representing at least a portion of the buried pipeline extending across the geographical area being surveyed. The program further includes instructions for displaying a current plot of current values associated with the various locations in the geographical area, and instructions for displaying a table having a plurality of fields including the leakage current values and associated geographical coordinates where the current values were measured in the geographical area being surveyed.

Abstract translation: 数据分析程序，可操作用于在地理区域中显示埋地管道的至少一个表示以及沿管道的不同位置处的相关管道电流值。 数据分析程序可存储在存储器设备中并且可由处理器执行以在显示设备上生成显示。 数据分析程序包括用于显示数字地图的指令，该数字地图表示跨越被测地理区域延伸的埋管道的至少一部分。 该程序还包括用于显示与地理区域中的各个位置相关联的当前值的当前图的指令，以及用于显示具有多个场的表的指令，该表具有包括当前值被测量的泄漏电流值和相关联的地理坐标 被调查的地理区域。

公开(公告)号：US20090307225A1

公开(公告)日：2009-12-10

申请号：US12089367

申请日：2006-10-06

Applicant: Ian Shaw Burnett ,  Stephen James Davis

Inventor： Ian Shaw Burnett ,  Stephen James Davis

IPC: G06F17/30 ,  G06F7/00

CPC classification number: G06F17/2247 ,  G06F16/8373 ,  G06F17/2229

Abstract: A method of facilitating access to a schema, the method comprising the steps of receiving a request from a first computing device for at least one fragment of the schema; identifying a second computing device that has access to the fragment of the schema; and providing the first computing device with a datum that enables the first computing device to retrieve the fragment of the schema from the second computing device to thereby facilitate access to the schema.

Abstract translation: 一种促进对模式的访问的方法，所述方法包括以下步骤：从所述模式的至少一个片段接收来自第一计算设备的请求; 识别能够访问所述模式的片段的第二计算设备; 以及向所述第一计算设备提供使得所述第一计算设备能够从所述第二计算设备检索所述模式的片段从而便于访问所述模式的数据。

公开(公告)号：US20090281829A1

公开(公告)日：2009-11-12

申请号：US12434244

申请日：2009-05-01

Applicant: Michael Hansen ,  Simon Dennison ,  Sue Meyer ,  Bipin Patel ,  Timothy James Davis

Inventor： Michael Hansen ,  Simon Dennison ,  Sue Meyer ,  Bipin Patel ,  Timothy James Davis

IPC: G06Q50/00

CPC classification number: G06Q30/02 ,  G06Q10/107 ,  G06Q50/22 ,  H04L51/00

Abstract: Systems, methods and computer program products for providing compliant messaging services are disclosed. Methods according to some embodiments include receiving input data from a campaign sponsor, encrypting at least a portion of the input data, generating a message schedule that includes message content, recipient identification data and temporal data corresponding to a plurality of messages, and sending and/or receiving one of the plurality of messages to and/or from a corresponding recipient.

Abstract translation: 公开了用于提供符合消息服务的系统，方法和计算机程序产品。 根据一些实施例的方法包括从运动赞助者接收输入数据，加密输入数据的至少一部分，生成包括消息内容，接收者标识数据和对应于多个消息的时间数据的消息调度，以及发送和/ 或者从相应的接收者接收和/或从相应的接收者接收多个消息中的一个消息。

公开(公告)号：US20090205566A1

公开(公告)日：2009-08-20

申请号：US11658975

申请日：2005-08-05

Applicant: Iain Peter McGuffie ,  Jeremy Nicholls ,  Liam Darren Philpotts ,  James Phillip Ballard ,  Richard James Davis ,  Stewart Nathan Ridgley Swatton ,  Kevin James Palmer ,  Antony Willem Walker

Inventor： Iain Peter McGuffie ,  Jeremy Nicholls ,  Liam Darren Philpotts ,  James Phillip Ballard ,  Richard James Davis ,  Stewart Nathan Ridgley Swatton ,  Kevin James Palmer ,  Antony Willem Walker

IPC: B05C11/00

CPC classification number: A63C19/08 ,  A63C2019/067

Abstract: A line marking apparatus includes a chassis (2) provided with wheels (4) and with means (6) for propelling the apparatus. A line marking head (12) is adapted to dispense line marking material so as to mark a line upon a surface over which the apparatus is moved. A support (14) is provided for the line marking head such that the line marking head is movable laterally relative to the chassis. Lateral movement of the line marking head is controlled by a controller which includes a detector (32) for detecting a beam of electromagnetic radiation indicative of the line to be marked and which also includes control means for moving the line marking head in response to detection of the beam by the detector, whereby lateral movement of the line marking head relative to the chassis is controlled such that the line marking head substantially follows the line to be marked irrespective of whether the chassis deviates from the direction of such line.

Abstract translation: 线标记装置包括具有轮（4）的底盘（2）和用于推动该装置的装置（6）。 线标记头（12）适于分配线标记材料，以便在装置移动的表面上标记线。 为行标记头提供支撑件（14），使得线标记头相对于底盘可横向移动。 线标记头的横向移动由控制器控制，该控制器包括用于检测指示要标记的线的电磁辐射束的检测器（32），并且还包括用于响应于检测到的线的标记头移动的控制装置 通过检测器的光束，由此控制线标记头相对于底架的横向运动，使得线标记头基本上跟随待标记的线，而不管底盘是否偏离该线的方向。

公开(公告)号：US20080205575A1

公开(公告)日：2008-08-28

申请号：US11892596

申请日：2007-08-24

Applicant: David T. Morris ,  Terry Lynn Chapman ,  Trevor James Davis

Inventor： David T. Morris ,  Terry Lynn Chapman ,  Trevor James Davis

IPC: G21C17/06

CPC classification number: G21C17/003 ,  G21C17/013

Abstract: A method of inspecting or utilizing tools in the underwater environment of a nuclear reactor vessel, a spent fuel pool or equipment pit includes floating a platform for transporting inspection devices and/or tools over an underwater target site and deploying the devices or tools to the underwater target site. The platform may be coupled to a boom whose opposite end is carried by a cart movable about a floor area surrounding the pool. Alternatively, the platform may be independently movable along the water surface by thrusters.

Abstract translation: 在核反应堆船，废燃料池或设备坑的水下环境中检查或利用工具的方法包括：将用于在水下目标地点上运送检查装置和/或工具的平台漂浮并将装置或工具部署到水下 目标网站。 平台可以联接到吊杆，其相对端由围绕游泳池的地板区域可移动的推车承载。 或者，平台可以通过推进器独立地沿水面移动。

公开(公告)号：US20080131317A1

公开(公告)日：2008-06-05

申请号：US11923930

申请日：2007-10-25

Applicant: Paul James Davis ,  Michael Evans Prior ,  Keith May

Inventor： Paul James Davis ,  Michael Evans Prior ,  Keith May

IPC: B01J19/00

CPC classification number: G01N33/54386 ,  G01N33/558 ,  G01N33/76 ,  Y10S435/805 ,  Y10S435/806 ,  Y10S435/81 ,  Y10S435/97 ,  Y10S436/81 ,  Y10S436/814 ,  Y10S436/818

Abstract: An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile in the porous carrier when in the moist state, and an unlabelled specific binding reagent which is permanently immobilised in a detection zone on the carrier material, the labelled and unlabelled specific binding reagents being capable of participating in either a sandwich reaction or a competition reacts on in the presence of the analyte, in which prior to the application to the device of a liquid sample suspected of containing the analyte, the labelled specific binding reagent is retained in the dry state in a macroporous body, eg. of plastics material having a pore size of 10 microns or greater, through which the applied liquid sample must pass en route to the porous carrier material, the labelled specific binding reagent being freely soluble or dispersible in any liquid sample which enters the macroporous body.

Abstract translation: 包含干多孔载体的分析测试装置，液体样品例如 怀疑含有分析物如HCG或LH的尿液可以间接施用，该装置还包含标记的特异性结合试剂，其在潮湿状态下可自由移动到多孔载体中，以及未标记的特异性结合试剂，其被永久固定 在载体材料上的检测区域中，能够参与夹心反应或竞争性的标记和未标记的特异性结合试剂在分析物存在下反应，其中在施加到液体样品的装置之前 怀疑含有分析物，标记的特异性结合试剂在大孔体内保持干燥状态，例如。 的孔径为10微米或更大的塑料材料，所施加的液体样品通过该材料必须通过多孔载体材料，标记的特异性结合试剂可自由溶解或分散在进入大孔体的任何液体样品中。

公开(公告)号：US07365200B2

公开(公告)日：2008-04-29

申请号：US11687598

申请日：2007-03-16

Applicant: Jagadish Sircar ,  Sunil Kumar K. C. ,  Timothy James Davis ,  Wenbin Ying

Inventor： Jagadish Sircar ,  Sunil Kumar K. C. ,  Timothy James Davis ,  Wenbin Ying

IPC: C07D495/04 ,  A61K31/496

CPC classification number: C07D495/04 ,  C07D498/02

Abstract: Inhibitors of macrophage migration inhibitory factor having a thienopyridinone backbone are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with macrophage migration inhibitory factor activity. The inhibitors of macrophage migration inhibitory factor have the following structures: including forms such as stereoisomers, free forms, pharmaceutically acceptable salts or esters thereof, solvates, or combinations of such forms, wherein n, R1, R2, R3, X, and Y are as defined herein. Compositions comprising an inhibitor of macrophage migration inhibitory factor in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.

Abstract translation: 提供具有噻吩并吡啶酮骨架的巨噬细胞迁移抑制因子的抑制剂，其可用于治疗各种疾病，包括治疗与巨噬细胞迁移抑制因子活性相关的病理状况。 巨噬细胞迁移抑制因子的抑制剂具有以下结构：包括形式如立体异构体，游离形式，药学上可接受的盐或酯，溶剂合物或这些形式的组合，其中n，R 1，R R 3，R 3，X和Y如本文所定义。 还提供了包含与药学上可接受的载体组合的巨噬细胞迁移抑制因子抑制剂的组合物，以及其用途的方法。