公开(公告)号：US11732221B2

公开(公告)日：2023-08-22

申请号：US16649350

申请日：2018-10-02

Applicant: Novozymes A/S

Inventor： Tine Hoff ,  Markus Klinger

IPC: C11D3/386 ,  C12N9/24 ,  C12N1/14 ,  C12N1/16 ,  C12N1/20 ,  C12P19/14 ,  C11D17/00

CPC classification number: C11D3/38636 ,  C11D3/386 ,  C11D17/0004 ,  C11D17/0039 ,  C12N1/14 ,  C12N1/16 ,  C12N1/20 ,  C12N9/2488 ,  C12N9/2491 ,  C12P19/14 ,  C12Y302/01025

Abstract: The present invention relates to polypeptides having mannanase activity, catalytic domains, and carbohydrate binding modules, and polynucleotides encoding the polypeptides, catalytic domains, and carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, and carbohydrate binding modules.

公开(公告)号：US20230242960A1

公开(公告)日：2023-08-03

申请号：US17794408

申请日：2021-01-12

Applicant: Novozymes A/S

Inventor： Gloria Erichsen

IPC: C12P21/02 ,  C12N15/80 ,  C12N9/14 ,  C12N1/14 ,  C12R1/885

CPC classification number: C12P21/02 ,  C12N15/80 ,  C12N9/14 ,  C12N1/14 ,  C12R2001/885 ,  C12Y306/05

Abstract: The present invention relates to a mutant of a parent filamentous fungal cell, comprising: a polynucleotide encoding a polypeptide of interest; a racA gene encoding a Rho-GTPase RacA protein, wherein the racA gene is modified rendering the mutant partially or completely deficient in the production of the Rho-GTPase RacA protein; and a ras2 gene encoding a GTPase Ras2 protein, wherein the GTPase Ras2 protein is modified to produce a GTPase Ras2 variant comprising a substitution at a position corresponding to position 16 of SEQ ID NO: 11, wherein the combination of the modified racA gene and the Ras2 variant synergistically increases the productivity of the mutant in the production of the polypeptide of interest. The present invention also relates to a method of producing a polypeptide of interest with such a mutant.

公开(公告)号：US20230220307A1

公开(公告)日：2023-07-13

申请号：US17998315

申请日：2021-06-01

Applicant: Novozymes A/S

Inventor： Kenneth Edmund Kellar ,  Hilary Cheeseman ,  John Harp

IPC: C11D3/38 ,  C11D1/29 ,  C11D1/66

CPC classification number: C11D3/381 ,  C11D1/29 ,  C11D1/662

Abstract: The invention provides an aqueous microbial cleaning composition having excellent storage and germination properties, comprising bacterial spores and alkyl polyglucosides or sodium lauryl ether sulfates.

公开(公告)号：US20230212548A1

公开(公告)日：2023-07-06

申请号：US17927164

申请日：2021-05-26

Applicant: Novozymes A/S

Inventor： Esben Peter Friis ,  Rolf Thomas Lenhard ,  Lars Lehmann Hylling Christensen ,  Julie Bille Rannes

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C12Y304/21062 ,  C11D3/386

Abstract: The invention relates to subtilase variants, compositions comprising the variants, and methods of using the variants and compositions, e.g. for laundry or hard surface cleaning such as dishwashing.

公开(公告)号：US11685910B2

公开(公告)日：2023-06-27

申请号：US16861471

申请日：2020-04-29

Applicant: NOVOZYMES A/S

Inventor： Zhengfang Kang ,  Kirk Matthew Schnorr ,  Lar Kobberøe Skov

IPC: C12N15/82 ,  C12N9/24 ,  C12P7/06 ,  C12P7/10

CPC classification number: C12N9/2402 ,  C12P7/06 ,  C12P7/10 ,  C12Y302/01028 ,  Y02E50/10

Abstract: The present invention relates to polypeptides having trehalase activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using a trehalase of the invention, in particular a process of producing a fermentation product, such as ethanol.

公开(公告)号：US20230193216A1

公开(公告)日：2023-06-22

申请号：US17924944

申请日：2021-05-12

Applicant: Novozymes A/S

Inventor： Monica Tassone ,  Eric Allain

IPC: C12N9/02 ,  C12P7/10

CPC classification number: C12N9/0008 ,  C12Y102/01009 ,  C12P7/10

Abstract: Described herein are recombinant host organisms having an active pentose fermentation pathway and further comprising a heterologous polynucleotide encoding a non-phosphorylating NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPN). Also described are processes for producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant host organisms.

公开(公告)号：US20230193162A1

公开(公告)日：2023-06-22

申请号：US16651264

申请日：2018-10-15

Applicant: Novozymes A/S

Inventor： Ole Simonsen ,  Poul Bach ,  Albert Cervera-Padrell ,  Lars Jensen ,  Lei Shang ,  Lotte Elisabeth Nissen

IPC: C11D3/38 ,  C11D3/386 ,  C11D3/20 ,  C11D17/06 ,  C11D3/04 ,  C11D3/12 ,  C11D17/00

CPC classification number: C11D3/381 ,  C11D3/386 ,  C11D3/2065 ,  C11D17/06 ,  C11D3/046 ,  C11D3/1253 ,  C11D17/0039

Abstract: The invention provides a method for preparing a plurality of granules comprising a biological active and a non-volatile liquid by using mixer-granulation, wherein the granules exhibit reduced dust release upon exposure to mechanical stress.

公开(公告)号：US20230180791A1

公开(公告)日：2023-06-15

申请号：US17925445

申请日：2021-05-18

Applicant: DSM IP ASSETS B.V. ,  NOVOZYMES A/S

Inventor： Aaron COWIESON ,  Jose-Otavio SORBARA ,  Levy DO VALE TEIXEIRA ,  Carrie WALK

IPC: A23K10/14 ,  A23K10/30 ,  A23K20/147 ,  C12N9/40 ,  C12N9/24

CPC classification number: A23K10/14 ,  A23K10/30 ,  A23K20/147 ,  C12N9/2465 ,  C12N9/2482 ,  C12Y302/01008 ,  C12Y302/01022

Abstract: The present invention relates to uses of at least one carbohydrase in combination with an animal feed with a defined A/X fiber fraction, to an animal feed with a defined A/X fiber fraction and comprising at least one carbohydrase in an amount determined suitable to the A/X fiber fraction of the feed and methods of making thereof.

公开(公告)号：US11667922B2

公开(公告)日：2023-06-06

申请号：US17040906

申请日：2019-03-25

Applicant: Novozymes A/S

Inventor： Jean-Marie Mouillon ,  Pernille Hvid Christensen

IPC: C12N15/80

CPC classification number: C12N15/80

Abstract: The present invention relates to fungal host cells comprising nucleic acid constructs comprising a heterologous promoter operably linked to polynucleotidea encoding a chaperone, nucleic acid constructs comprising a polynucleotide encoding a chaperone, and methods for producing polypeptides of interest.

公开(公告)号：US20230167384A1

公开(公告)日：2023-06-01

申请号：US17913103

申请日：2021-04-20

Applicant: Novozymes A/S

Inventor： Marc Dominique Morant ,  Lorena Gonzalez Palmen ,  Klaus Gori ,  Jesper Salomon

IPC: C11D3/386 ,  C11D3/395 ,  C11D3/37

CPC classification number: C11D3/38636 ,  C11D3/3951 ,  C11D3/37

Abstract: The invention relates to cleaning compositions comprising a fructan degrading enzyme and at least one cleaning component, and use of such compositions for cleaning of an item such as a textile or a surface.