公开(公告)号：US20080153104A1

公开(公告)日：2008-06-26

申请号：US10568471

申请日：2004-08-06

Applicant: Hiroyuki Aburatani ,  Yoshitaka Hippo ,  Hirokazu Taniguchi ,  Yong xin Chen ,  Shumpei Ishikawa ,  Shin-ichi Fukumoto ,  Takahiro Shimamura ,  Naoko Kamimura ,  Ying qiu Guo ,  Shogo Yamamoto ,  Yukio Ito ,  Hirotaka Ito ,  Toshihiko Ohtomo

Inventor： Hiroyuki Aburatani ,  Yoshitaka Hippo ,  Hirokazu Taniguchi ,  Yong xin Chen ,  Shumpei Ishikawa ,  Shin-ichi Fukumoto ,  Takahiro Shimamura ,  Naoko Kamimura ,  Ying qiu Guo ,  Shogo Yamamoto ,  Yukio Ito ,  Hirotaka Ito ,  Toshihiko Ohtomo

IPC: G01N33/53 ,  G01N33/48 ,  G01N33/566 ,  C12Q1/02

CPC classification number: C12Q1/6886 ,  A61K31/711 ,  A61K38/00 ,  A61K39/0011 ,  C07K14/82 ,  C07K16/30 ,  C12Q2600/136 ,  G01N33/57484

Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.

Abstract translation: 公开了由具有由SEQ ID NO：1至65中任一个表示的核苷酸序列或其片段的基因编码的蛋白质，识别该蛋白质或其抗原结合片段的抗体，以及具有至少12个 由SEQ ID NO：1至65中任一个表示的核苷酸序列的连续核苷酸或与其互补的核苷酸序列。 本发明的基因和蛋白质可用于诊断和治疗癌症。

公开(公告)号：US20070177846A1

公开(公告)日：2007-08-02

申请号：US11483229

申请日：2006-07-07

Applicant: Xin Chen ,  Ji Wang ,  Joohyun Koh ,  Ming-Jun Li ,  Daniel Nolan ,  Donnell Walton ,  Luis Zenteno

Inventor： Xin Chen ,  Ji Wang ,  Joohyun Koh ,  Ming-Jun Li ,  Daniel Nolan ,  Donnell Walton ,  Luis Zenteno

IPC: G02B6/032 ,  G02B6/02 ,  G02B6/036 ,  G02B6/00

CPC classification number: G02B6/024 ,  C03B37/01217 ,  C03B37/01413 ,  C03B2201/12 ,  C03B2201/31 ,  C03B2201/36 ,  C03B2201/50 ,  C03B2203/12 ,  C03B2203/14 ,  C03B2203/22 ,  C03B2203/31 ,  C03B2205/10 ,  C03B2207/90 ,  G02B6/105 ,  H01S3/06712 ,  H01S3/06729 ,  H01S3/094007

Abstract: An optical fiber including: (i) a silica based, rare earth doped core having a first index of refraction n1; and (ii) at least one silica based cladding surrounding the core and having a second index of refraction n2, such that n1>n2, said cladding having a plurality of stress rods and a plurality of air holes extending longitudinally through the length of said optical fiber; wherein said optical fiber supports a single polarization mode or poses-polarization maintaining properties within the operating wavelength range.

Abstract translation: 一种光纤，包括：（i）具有第一折射率n 1的二氧化硅基稀土掺杂的芯; 和（ii）至少一个二氧化硅基包层，其围绕所述芯并且具有第二折射率n 2 2，使得n 1/2 2

公开(公告)号：US20070165978A1

公开(公告)日：2007-07-19

申请号：US11331905

申请日：2006-01-13

Applicant: Xin Chen ,  Alan Evans ,  Joohyun Koh ,  Ming-Jun Li ,  Daniel Nolan

Inventor： Xin Chen ,  Alan Evans ,  Joohyun Koh ,  Ming-Jun Li ,  Daniel Nolan

IPC: G02B6/00

CPC classification number: C03B37/07 ,  C03B37/0124 ,  C03B2203/14 ,  G01M11/3181 ,  Y02P40/57

Abstract: A method for measuring fundamental mode cutoff wavelength of single polarization fiber comprising: (i) launching pulsed light of at least one wavelength λi into one end of the single polarization fiber; (ii) measuring backscattered light intensity corresponding to said wavelength to obtain the backscattered light intensity as a function of fiber position, wherein the backscattered light propagates through the same end of the fiber; and (iii) determining at least one cutoff wavelength and the corresponding position within said fiber for the cutoff wavelength, based on a specified threshold light intensity level.

Abstract translation: 一种用于测量单极化光纤的基模截止波长的方法，包括：（i）将至少一个波长λλ的脉冲光发射到单极化光纤的一端; （ii）测量对应于所述波长的反向散射光强度以获得作为光纤位置的函数的背向散射光强度，其中所述反向散射光通过所述光纤的同一端传播; 以及（iii）基于指定的阈值光强度水平确定所述光纤中的至少一个截止波长和所述光纤中的对应位置作为所述截止波长。

公开(公告)号：US20070116416A1

公开(公告)日：2007-05-24

申请号：US11453450

申请日：2006-06-14

Applicant: Xin Chen ,  Stuart Gray ,  Ming-Jun Li ,  Daiping Ma ,  Daniel Nolan ,  Alranzo Ruffin ,  Donnell Walton ,  Ji Wang

Inventor： Xin Chen ,  Stuart Gray ,  Ming-Jun Li ,  Daiping Ma ,  Daniel Nolan ,  Alranzo Ruffin ,  Donnell Walton ,  Ji Wang

IPC: G02B6/02

CPC classification number: G02B6/03694 ,  G02B6/02 ,  G02B6/02019 ,  G02B6/02266 ,  G02B6/02271 ,  G02B6/02276 ,  G02B6/0281 ,  G02B6/03644 ,  H01S3/06708

Abstract: An optical fiber comprising a core having a refractive index profile and a centerline; and a cladding layer surrounding and directly adjacent the core; wherein core includes updoping material and is doped with Aluminum in at least one region of the core, such that either: (a) the average longitudinal acoustic wave velocity within the core is within 0.05% of the longitudinal acoustic wave velocity within the cladding; or (b) the longitudinal acoustic wave velocity in the core changes by at least 0.2%.

Abstract translation: 一种光纤，包括具有折射率分布和中心线的芯; 以及围绕并直接邻近所述芯的包层; 其中芯包括更新材料并且在芯的至少一个区域中掺杂有铝，使得：（a）芯内的平均纵向声波速度在包层内的纵向声波速度的0.05％以内; 或（b）芯中的纵向声波速度变化至少0.2％。

公开(公告)号：US07221439B2

公开(公告)日：2007-05-22

申请号：US11118302

申请日：2005-04-29

Applicant: Xin Chen ,  Charles F. Laing ,  Ming-Jun Li ,  Sonya M. Raney

Inventor： Xin Chen ,  Charles F. Laing ,  Ming-Jun Li ,  Sonya M. Raney

IPC: G01N21/00

CPC classification number: G01M11/332 ,  G01M11/3163 ,  G01M11/338

Abstract: A method for measuring longitudinal variation in chromatic dispersion in an optical fiber, comprising: (i) launching into a first end and a second end of optical fiber an optical signal at a wavelength λ1 to collect backscatter power P(z) for different positions z within said optical fiber and providing measured OTDR backscatter traces; (ii) deriving from the measured OTDR backscatter traces at the single OTDR wavelength λ1 either (a) the longitudinal MFD(z) data or (b) the relative MFD data; and (iii) calculating estimated longitudinal dispersion D(z) from the longitudinal MFD(z) data or the relative MFD data, without utilizing any other wavelength data.

Abstract translation: 一种用于测量光纤中色散的纵向变化的方法，包括：（i）向光纤的第一端和第二端发射波长为λ1的光信号以收集反向散射功率 P（z）用于所述光纤内的不同位置z，并提供测量的OTDR后向散射迹线; （ii）（a）纵向MFD（z）数据或（b）相对MFD数据在单个OTDR波长λ1下从所测量的OTDR反向散射迹线得出; 和（iii）从纵向MFD（z）数据或相对MFD数据计算估计的纵向色散D（z），而不使用任何其它波长数据。

公开(公告)号：US20070107036A1

公开(公告)日：2007-05-10

申请号：US10580499

申请日：2004-11-25

Applicant: Ningjiang Chen ,  Fons Bruls ,  Yongqin Zeng ,  Xin Chen

Inventor： Ningjiang Chen ,  Fons Bruls ,  Yongqin Zeng ,  Xin Chen

IPC: H04N7/16

CPC classification number: H04N21/4382 ,  H04H20/14 ,  H04N7/163 ,  H04N7/173 ,  H04N21/2547 ,  H04N21/4325 ,  H04N21/44004 ,  H04N21/44209 ,  H04N21/458 ,  H04N21/64322 ,  H04N21/6582 ,  H04N21/812

Abstract: This invention provides a method that when the disturbance of the bandwidth or the signal quality occurs during the digital program broadcasting, so that the broadcasting quality of the currently broadcast normal program is below a predetermined value, a prearranged program having a specific broadcasting quality, such as advertisements, will be inserted. The prearranged program may have an regular relation to the currently broadcast normal program, thereby the user would rather appreciate some program than suffer bad screen showing or wait until the program returns back to a good condition to be watched normally. This invention further provides a method for making statistics of the inserted prearranged program, said statistical information could be used for charging.

Abstract translation: 本发明提供了一种方法，当在数字节目广播期间发生带宽干扰或信号质量时，使得当前广播正常节目的广播质量低于预定值，具有特定广播质量的预先排列的节目， 作为广告，将被插入。 预先安排的节目可能与当前广播的普通节目有规律的关系，因此用户宁可欣赏某些节目，而不是遭受坏屏幕显示或等待，直到节目返回到要正常观看的良好状态。 本发明还提供了一种用于对插入的预先安排的程序进行统计的方法，所述统计信息可用于计费。

公开(公告)号：US20070100833A1

公开(公告)日：2007-05-03

申请号：US10596180

申请日：2004-12-07

Applicant: Xin Chen ,  Ningjiang Chen ,  Yongqin Zeng

Inventor： Xin Chen ,  Ningjiang Chen ,  Yongqin Zeng

IPC: G06F17/30

CPC classification number: G06F16/9562

Abstract: The present invention provides a method for creating an electronic bookmark during browsing on a web. According to a predetermined sequence the method records the process of browsing the specific program content by an user and stores the process in a storing means. The stored content is a browsing command for requiring a specific server to send the program content from an random position in a specific program specified by an user. When a user clicks the bookmark, a series of requests contained in the bookmark are handled one by one in the batch-handling manner, so that the user can directly and accurately find the specific position in the specific program in a on-line manner in the web, as conveniently as using conventional bookmarks in the conventional books.

Abstract translation: 本发明提供了一种在网页浏览时创建电子书签的方法。 根据预定顺序，该方法记录用户浏览特定节目内容的过程，并将该处理存储在存储装置中。 所存储的内容是用于要求特定服务器从由用户指定的特定程序中的随机位置发送节目内容的浏览命令。 当用户点击书签时，以批处理方式一个一个地处理书签中包含的一系列请求，使得用户可以以在线方式直接且准确地在特定程序中找到特定位置 该网络与传统书籍中使用常规书签一样方便。

公开(公告)号：US07194172B2

公开(公告)日：2007-03-20

申请号：US10864732

申请日：2004-06-09

Applicant: George E. Berkey ,  Xin Chen ,  Ming-Jun Li ,  Daniel A. Nolan ,  William A. Wood

Inventor： George E. Berkey ,  Xin Chen ,  Ming-Jun Li ,  Daniel A. Nolan ,  William A. Wood

IPC: G02B6/02 ,  G02B6/36

CPC classification number: C03B37/02781 ,  C03B37/01217 ,  C03B37/01234 ,  C03B2203/30 ,  C03B2203/302 ,  C03B2205/08 ,  C03B2205/10 ,  G02B6/02 ,  G02B6/02366 ,  G02B6/024 ,  G02B6/0281 ,  G02B6/03627 ,  G02B6/03655 ,  G02B6/03694

Abstract: An optical fiber that includes a central core having a maximum dimension (A) greater than a minimum dimension (B), preferably with an aspect ratio greater than 1.5, the fiber having at least one air hole positioned on opposite sides of the central core and extending along the fiber's length wherein the fiber supports a single polarization mode within an operating wavelength band. The fiber may be coupled to optical components in systems to provide single polarization in the band. A method for manufacturing the fiber is also provided.

Abstract translation: 一种光纤，包括具有大于最小尺寸（B）的最大尺寸（A）的中心芯，优选地具有大于1.5的纵横比，所述纤维具有位于所述中心芯的相对侧上的至少一个空气孔，以及 沿着光纤的长度延伸，其中光纤在工作波长带内支持单一偏振模式。 光纤可以耦合到系统中的光学部件，以在带中提供单极化。 还提供了一种制造纤维的方法。

公开(公告)号：US20070015926A1

公开(公告)日：2007-01-18

申请号：US11413688

申请日：2006-04-28

Applicant: Xin Chen ,  Yicheng Mei

Inventor： Xin Chen ,  Yicheng Mei

IPC: C07D339/04

CPC classification number: C07D339/04

Abstract: The present invention discloses a method for preparing R-(+)-LA as well as its metal salts including sodium salt, potassium salt, calcium salt, magnesium salt, zinc salt, ferric salt, cooper salt , lithium salt and its organic salt, wherein a racemic Ethyl 6, 8-Dichlorooctanoic acid is employed as starting agents, followed by a hydrolysis and resolution processes to obtain (+)DCA, and then through sulfuration and cyclization process to obtain R-(+)-LA as well as its varied salts. A method for converting the (−)DCA to (+)DCA is also introduced.

Abstract translation: 本发明公开了一种制备R - （+） - LA及其金属盐的方法，包括钠盐，钾盐，钙盐，镁盐，锌盐，铁盐，铜盐，锂盐及其有机盐， 其中使用外消旋的6,8-二氯辛酸作为起始剂，然后进行水解和拆分方法以获得（+）DCA，然后通过硫化和环化过程获得R - （+） - LA及其 各种盐。 还引入了（ - ）DCA转换为（+）DCA的方法。

公开(公告)号：US07158705B2

公开(公告)日：2007-01-02

申请号：US10930889

申请日：2004-08-30

Applicant: George E Berkey ,  Xin Chen ,  Ming-Jun Li ,  Daniel A Nolan ,  Ji Wang ,  William A Wood ,  Luis A Zenteno

Inventor： George E Berkey ,  Xin Chen ,  Ming-Jun Li ,  Daniel A Nolan ,  Ji Wang ,  William A Wood ,  Luis A Zenteno

IPC: G02B6/02

CPC classification number: G02B6/024 ,  C03B37/01217 ,  C03B37/014 ,  C03B37/01466 ,  C03B2201/12 ,  C03B2201/31 ,  C03B2203/10 ,  C03B2203/12 ,  C03B2203/16 ,  C03B2203/22 ,  C03B2203/30 ,  C03B2203/31

Abstract: According to the present invention the optical fiber includes a core with a first refractive index (n1) and the innermost core region with the refractive index n0, a cladding surrounding the core, the cladding having a third refractive index (n3), wherein n1>n3 and n0 n2. It is preferable that at least one of the core, innermost core region and/or moat has a non-circular shape.

Abstract translation: 根据本发明，光纤包括具有第一折射率（n <1> 1）的核心和折射率为n <0的最内芯区域，围绕 芯，所述包层具有第三折射率（n 3/3），其中n 1 n 3 n 3和n 0 。 根据一些实施例，光纤还可以包括环绕并邻接芯并且位于芯和包层之间的护城河，护城河具有第二折射率（n2> 2），其中n < SUB> 3 n <2> 。 优选核心，最内芯区域和/或护城河中的至少一个具有非圆形形状。