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97 条记录 (耗时 0.033 秒)

    Percutaneous mitral annuloplasty with hemodynamic monitoring
    61.
    发明授权
    Percutaneous mitral annuloplasty with hemodynamic monitoring 有权
    经皮二尖瓣成形术与血液动力学监测

    公开(公告)号：US07935146B2

    公开(公告)日：2011-05-03

    申请号：US10806906

    申请日：2004-03-23

    申请人： Jonathan J. Langberg ,  Michael D. Lesh

    发明人： Jonathan J. Langberg ,  Michael D. Lesh

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2451 ,  A61F2/2466 ,  A61N2001/0585

    摘要： A minimally invasive method of performing mitral annuloplasty is disclosed. An implantable device is positioned within the coronary sinus and tightened around the mitral annulus. Mitral valve regurgitation is monitored before, during, and/or after the tightening step. An on-going drug therapy may be determined, taking into account post-implantation hemodynamic function.

    摘要翻译： 公开了进行二尖瓣瓣环成形术的微创方法。 可植入装置位于冠状窦内并且紧固在二尖瓣环周围。 在紧固步骤之前，之中和/或之后监测二尖瓣反流。 可以确定正在进行的药物治疗，考虑到植入后血液动力学功能。

    PERCUTANEOUS MITRAL ANNULPLASTY WITH CARDIAC RHYTHM MANAGEMENT
    62.
    发明申请
    PERCUTANEOUS MITRAL ANNULPLASTY WITH CARDIAC RHYTHM MANAGEMENT 审中-公开
    具有CARDIAC RHYTHM管理的PERCUTANEOUS MITRAL ANNULPLASTY

    公开(公告)号：US20110009957A1

    公开(公告)日：2011-01-13

    申请号：US12883136

    申请日：2010-09-15

    申请人： Jonathan J. Langberg ,  Michael D. Lesh

    发明人： Jonathan J. Langberg ,  Michael D. Lesh

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451 ,  A61F2/2466 ,  A61N2001/0585

    摘要： A minimally invasive method of performing mitral annuloplasty is disclosed. An implantable device is positioned within the coronary sinus and tightened around the mitral annulus. Mitral valve regurgitation is monitored before, during, and/or after the tightening step. An on-going drug therapy may be determined, taking into account post-implantation hemodynamic function.

    摘要翻译： 公开了进行二尖瓣瓣环成形术的微创方法。 可植入装置位于冠状窦内并且紧固在二尖瓣环周围。 在紧固步骤之前，之中和/或之后监测二尖瓣反流。 可以确定正在进行的药物治疗，考虑到植入后血液动力学功能。

    COMPRESSIBLE COSMETIC PROSTHESIS WITH IMPROVED SHAPE RETENTION
    64.
    发明申请
    COMPRESSIBLE COSMETIC PROSTHESIS WITH IMPROVED SHAPE RETENTION 审中-公开
    具有改进形状保持性的可压缩化妆品

    公开(公告)号：US20090198330A1

    公开(公告)日：2009-08-06

    申请号：US12024843

    申请日：2008-02-01

    申请人： Randy J. Kesten ,  Michael D. Lesh

    发明人： Randy J. Kesten ,  Michael D. Lesh

    IPC分类号： A61F2/12

    CPC分类号： A61F2/12

    摘要： An implantable prosthesis is provided having a membrane which holds a flowable substance. The membrane is separated into a first chamber and a second chamber with the first and second chambers being fluidly coupled via an orifice. The orifice has a size which may be adjusted by the user after implanting the prosthesis into the patient.

    摘要翻译： 提供具有保持可流动物质的膜的可植入假体。 膜被分离成第一室和第二室，其中第一和第二室通过孔流体耦合。 孔口具有在将假体植入病人之后可由使用者调节的尺寸。

    Medical system and method for remodeling an extravascular tissue structure
    65.
    发明授权
    Medical system and method for remodeling an extravascular tissue structure 有权

    公开(公告)号：US06989028B2

    公开(公告)日：2006-01-24

    申请号：US10066302

    申请日：2002-01-30

    申请人： Randall T. Lashinski ,  Matthew J. Birdsall ,  Michael D. Lesh

    发明人： Randall T. Lashinski ,  Matthew J. Birdsall ,  Michael D. Lesh

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2451

    摘要： A medical apparatus and method suitable for remodeling a mitral valve annulus adjacent to the coronary sinus. The apparatus comprises an elongate body having a proximal region and a distal region. Each of the proximal and distal regions is dimensioned to reside completely within the vascular system. The elongate body may be moved from a first configuration for transluminal delivery to at least a portion of the coronary sinus to a second configuration for remodeling the mitral valve annulus proximate the coronary sinus. A forming element may be attached to the elongate body for manipulating the elongate body from the first transluminal configuration to the second remodeling configuration. Further, the elongate body may comprise a tube having a plurality of transverse slots therein.

    Circumferential ablation device assembly
    67.
    发明授权
    Circumferential ablation device assembly 有权
    周围消融装置组装

    公开(公告)号：US06872205B2

    公开(公告)日：2005-03-29

    申请号：US10133523

    申请日：2002-04-25

    申请人： Michael D. Lesh ,  Michael Ronald Ross ,  Jonathan J. Langberg ,  James C. Peacock, III

    发明人： Michael D. Lesh ,  Michael Ronald Ross ,  Jonathan J. Langberg ,  James C. Peacock, III

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B18/00 ,  A61B18/14 ,  A61N7/02 ,  A61B18/18

    CPC分类号： A61B18/1492 ,  A61B18/00 ,  A61B18/1815 ,  A61B2017/00243 ,  A61B2017/22038 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2018/00011 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00369 ,  A61B2018/00375 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/00994 ,  A61B2218/002 ,  A61N7/02

    摘要： This invention is a circumferential ablation device assembly which is adapted to forming a circumferential conduction block in a pulmonary vein. The assembly includes a circumferential ablation element which is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen, thereby transecting the electrical conductivity of the pulmonary vein against conduction along its longitudinal axis and into the left atrium. The circumferential ablation element includes an expandable member with a working length that is adjustable from a radially collapsed position to a radially expanded position. An equatorial band circumscribes the outer surface of the working length and is adapted to ablate tissue adjacent thereto when actuated by an ablation actuator. The equatorial band has a length relative to the longitudinal axis of the expandable member that is narrow relative to the working length, and is also substantially shorter than its circumference when the working length is in the radially expanded position. A pattern of insulators may be included over an ablation element which otherwise spans the working length in order to form the equatorial band described. The expandable member is also adapted to conform to the pulmonary vein in the region of its ostium, such as by providing a great deal of radial compliance or by providing a taper along the working length which has a distally reducing outer diameter. A linear ablation element is provided adjacent to the circumferential ablation element in a combination assembly which is adapted for use in a less-invasive “maze”-type procedure in the region of the pulmonary vein ostia in the left ventricle.

    摘要翻译： 本发明是适于在肺静脉中形成圆周传导阻滞的周缘消融装置组件。 该组件包括圆周消融元件，其适于沿着围绕肺静脉管腔的肺静脉壁消融组织的周缘区域，从而横切肺静脉的导电性，以抵抗沿着其纵向轴线并进入左心房的传导。 周向消融元件包括可膨胀构件，其具有可从径向收缩位置到径向扩张位置的可调节的工作长度。 赤道带包围工作长度的外表面，并且适于在由消融致动器致动时消融邻近的组织。 赤道带相对于可扩展构件的纵向轴线具有相对于工作长度窄的长度，并且当工作长度处于径向扩张位置时也比其圆周短得多。 绝缘体的图案可以包括在消融元件上，否则将跨越工作长度以形成所描述的赤道带。 可膨胀构件还适于在其口部的区域中符合肺静脉，例如通过提供大量径向顺应性或通过沿具有远端减小外径的工作长度提供锥形。 在组合组件中邻近周缘消融元件提供线性消融元件，该组合组件适用于在左心室的肺静脉口区域中的侵入性较小的“迷宫”型手术。

    Percutaneous mitral annuloplasty with hemodynamic monitoring
    70.
    发明授权
    Percutaneous mitral annuloplasty with hemodynamic monitoring 有权
    经皮二尖瓣成形术与血液动力学监测

    公开(公告)号：US06709456B2

    公开(公告)日：2004-03-23

    申请号：US09968272

    申请日：2001-10-01

    申请人： Jonathan J. Langberg ,  Michael D. Lesh

    发明人： Jonathan J. Langberg ,  Michael D. Lesh

    IPC分类号： A61F206

    CPC分类号： A61F2/2451 ,  A61F2/2466 ,  A61N2001/0585

    摘要： A minimally invasive method of performing mitral annuloplasty is disclosed. An implantable device is positioned within the coronary sinus and tightened around the mitral annulus. Mitral valve regurgitation is monitored before, during, and/or after the tightening step. An on-going drug therapy may be determined, taking into account post-implantation hemodynamic function.

    摘要翻译： 公开了进行二尖瓣瓣环成形术的微创方法。 可植入装置位于冠状窦内并且紧固在二尖瓣环周围。 在紧固步骤之前，之中和/或之后监测二尖瓣反流。 可以确定正在进行的药物治疗，考虑到植入后血液动力学功能。