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公开(公告)号：US20090012454A1
公开(公告)日：2009-01-08
申请号：US11773746
申请日：2007-07-05
申请人： Robert W. Childers
发明人： Robert W. Childers
IPC分类号： A61M1/14
CPC分类号： A61M1/28 , A61M1/284 , A61M1/288 , A61M5/44 , A61M39/14 , A61M2205/122 , A61M2205/3368 , G01J5/089
摘要： A dialysis system includes a dialysis instrument; a disposable item configured to hold a dialysis fluid and including an at least substantially opaque portion and an at least substantially clear portion; at least one non-invasive temperature sensor mounted to the dialysis instrument so as to be pointed selectively at the at least substantially clear portion and the at least substantially opaque portion; and a processor configured to calculate a temperature of the dialysis fluid within the disposable item using (i) a first temperature measurement from the at least one sensor while pointed at the at least substantially opaque portion, and (ii) a second temperature measurement from the at least one sensor pointed at the at least substantially clear portion.
摘要翻译： 透析系统包括透析仪器; 配置成保持透析流体并且包括至少基本上不透明的部分和至少基本上清楚的部分的一次性物品; 至少一个非侵入式温度传感器，其被安装到所述透析仪器上，以便被选择性地指向所述至少基本上透明的部分和所述至少基本上不透明的部分; 以及处理器，被配置为使用（i）来自所述至少一个传感器的第一温度测量来计算所述一次性物品内的透析液的温度，同时指向所述至少基本上不透明的部分，以及（ii）来自所述至少一个传感器的第二温度测量 至少一个传感器指向至少基本上清晰的部分。
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公开(公告)号：US5876664A
公开(公告)日：1999-03-02
申请号：US664985
申请日：1996-06-14
CPC分类号： A61L2/208 , A61L2/24 , G05D23/1935 , A61L2202/122 , A61L2202/24
摘要： The invention provides a method and apparatus for minimizing heat degradation of a vapor decontaminant in a vaporizer by selectively operating a plurality of vaporizer heaters to provide a decreasing heat gradient through the vaporizer. A method and apparatus are also provided for selectively operating a plurality of preheaters, in series, for preheating a carrier gas entering a vaporizer in a flow-through decontamination system, and for maintaining a predetermined carrier gas temperature. A further method and apparatus are provided for fine-tuning chamber pressure in a high flow rate closed-loop flow-through vapor phase decontamination system.
摘要翻译： 本发明提供了一种用于通过选择性地操作多个蒸发器加热器以减少通过蒸发器的热梯度来最小化汽化器中的蒸气去污剂的热降解的方法和装置。 还提供了一种方法和装置，用于选择性地操作多个串联的预热器，用于预热在流通净化系统中进入蒸发器的载气，并保持预定的载气温度。 提供了一种用于在高流量闭环流通气相净化系统中微调腔室压力的方法和装置。
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公开(公告)号：US5830409A
公开(公告)日：1998-11-03
申请号：US582731
申请日：1996-01-04
CPC分类号： A61L2/20
摘要： Hot, saturated water vapor in the form of low-temperature subatmospheric steam is employed to shorten the aeration period after sterilization with a condensable, heat-labile chemical sterilant. The application of steam accelerates the rate of outgassing of sterilant residuals that are absorbed into, or adsorbed or condensed onto chamber or load materials. The method is particularly suitable for removing residuals from polymeric materials and/or materials that are poor heat conductors. Apparatus is provided to supply steam in situations where a utility steam supply is not available.
摘要翻译： 使用低温低于大气压蒸汽形式的热的饱和水蒸气来缩短用可冷凝的热不稳定的化学灭菌剂灭菌后的通气时间。 蒸汽的应用加速了吸收或吸附或冷凝到室或负载材料上的灭菌剂残留物的除气速率。 该方法特别适于从聚合材料和/或不良热导体的材料中除去残余物。 在没有公用蒸汽供应的情况下提供设备来提供蒸汽。
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公开(公告)号：US5556607A
公开(公告)日：1996-09-17
申请号：US530577
申请日：1995-09-19
CPC分类号： A61L2/208 , A61L2/20 , A61L2/24 , A61C1/0076 , A61C19/002 , A61L2202/122 , A61L2202/24
摘要： The present invention provides a sterilization process particularly well suited for sterilizing instruments and other devices having long narrow lumens. Apparatus in which the process can be practiced is also provided. The process uses a multicomponent sterilant vapor wherein one component is water. The lumened instruments are fluidly connected to the exhaust manifold of the sterilizer. A deep vacuum is drawn in the sterilization chamber followed by the injection of pulses of the sterilant vapor until a higher, but still subatmospheric pressure level is reached. When the pressure level reaches a predetermined subatmospheric level, a flow-through sterilization phase begins. It includes successive alternating periods of sterilant flow and the discontinuance of such flow. During sterilant flow periods, there are sterilant injection pulses where the sterilant flows through the chamber and the lumened instruments to exhaust. Each such flow period is followed by a hold period. Following the sterilization phase, there are one or more aeration steps to remove sterilant from the chamber.
摘要翻译： 本发明提供了一种特别适用于消毒器具和其他具有较长腔体的器具的灭菌方法。 还提供了可以实施该方法的装置。 该方法使用多组分灭菌剂蒸气，其中一种组分是水。 流明的仪器与灭菌器的排气歧管流体连接。 在灭菌室中抽取深度真空，然后注入灭菌剂蒸气的脉冲，直到达到较高但仍低于大气压的压力水平。 当压力水平达到预定的低于大气压水平时，开始流通灭菌阶段。 它包括连续的交替周期的灭菌剂流动和这种流动的中断。 在灭菌剂流动期间，灭菌剂喷射脉冲，其中消毒剂流过腔室，并且流明的仪器排出。 每个这样的流动周期之后是保持期。 灭菌阶段之后，有一个或多个曝气步骤从室中除去灭菌剂。
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公开(公告)号：US4952370A
公开(公告)日：1990-08-28
申请号：US191310
申请日：1988-05-06
IPC分类号： A61L2/20
CPC分类号： A61L2/20
摘要： This process sterilizes the surfaces within a chamber wherein a first portion of the surfaces is at a temperature below 10.degree. C. and a second portion of the surfaces is at a temperature greater than 20.degree. C. The process includes the steps of introducing vapor phase hydrogen peroxide to the chamber, contacting the first portion with the vapor to effect condensation thereon, contacting the second portion with the vapor, applying a source of vacuum to the chamber and continuing to introduce vapor phase hydrogen peroxide into the chamber until the surfaces are sterile while preserving the temperature ranges of the first and second portions.
摘要翻译： 该过程对腔室内的表面进行灭菌，其中表面的第一部分处于低于10℃的温度，并且表面的第二部分处于大于20℃的温度。该方法包括以下步骤：将气相 过氧化氢到室中，使第一部分与蒸汽接触以在其上进行冷凝，使第二部分与蒸气接触，将真空源施加到室中，并继续将气相过氧化氢引入室中，直到表面无菌 同时保持第一和第二部分的温度范围。
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公开(公告)号：US4808377A
公开(公告)日：1989-02-28
申请号：US759539
申请日：1985-07-26
申请人： Robert W. Childers , Thomas G. Cook , David A. Karle , Ronald P. Krahe , George E. Sparber , Gerald L. Yeaney
发明人： Robert W. Childers , Thomas G. Cook , David A. Karle , Ronald P. Krahe , George E. Sparber , Gerald L. Yeaney
CPC分类号： A61L2/24
摘要： A self-contained, closed loop steam sterilizer having an integral external boiler. The sterilizer employs a prevacuum sterilization cycle with a dwell phase. A single pump accomplishes all pumping functions in a prioritized manner.
摘要翻译： 一个独立的闭环式蒸汽灭菌器，具有一体的外部锅炉。 灭菌器采用带有停留相的预真空灭菌循环。 单个泵以优先的方式实现所有泵送功能。
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公开(公告)号：US08900174B2
公开(公告)日：2014-12-02
申请号：US13373909
申请日：2011-12-05
申请人： Robert W. Childers
发明人： Robert W. Childers
CPC分类号： A61M1/284 , A61B5/02042 , A61M1/28 , A61M1/281 , A61M1/288 , A61M1/3621 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3644 , A61M1/3652 , A61M2205/122 , A61M2205/128 , A61M2205/70 , G01L7/00 , G01M3/04
摘要： A method for operating a dialysis cassette including a flexible membrane that covers a pump chamber includes applying a vacuum about a piston head and sucking the flexible membrane of the dialysis cassette onto the piston head; mechanically retracting the piston head along with the vacuum applied membrane away from the dialysis cassette to draw fluid into the pump chamber; mechanically extending the piston head and the flexible membrane into the pump chamber to expel fluid from the pump chamber through a flow path; and directly sensing a pressure of the fluid flowing through the flow path at a location of the dialysis cassette adjacent to the pump chamber.
摘要翻译： 用于操作包括覆盖泵室的柔性膜的透析盒的方法包括在活塞头周围施加真空并将透析盒的柔性膜吸入活塞头; 将活塞头与真空施加的膜一起远离透析盒机械地缩回以将流体引入泵室; 将活塞头和柔性膜机械地延伸到泵室中以通过流动路径从泵室排出流体; 并且在与所述泵室相邻的所述透析盒的位置处直接感测流过所述流路的流体的压力。
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68.发明授权公开(公告)号：US08715235B2
公开(公告)日：2014-05-06
申请号：US11773756
申请日：2007-07-05
申请人： Robert W. Childers , Bruce E. Huitt
发明人： Robert W. Childers , Bruce E. Huitt
CPC分类号： A61M1/28 , A61M1/284 , A61M1/288 , A61M2205/128 , A61M2205/3396 , A61M2209/084
摘要： A dialysis fluid flow control system includes a pumping cassette interface including a pump area operable with a pump chamber of a disposable cassette; the cassette interface further including a volumetric reference chamber used in a volumetric control of a dialysis fluid pumped pneumatically into and out of the pump chamber of the disposable cassette; a heater connected operably to the cassette interface; and a controller connected operably to the heater so as to cause the heater to heat at least a portion of the cassette interface to a desired temperature.
摘要翻译： 透析液流量控制系统包括泵壳接口，其包括可与一次性盒的泵室一起操作的泵区; 所述盒式接口还包括体积参考室，所述体积参考室用于气动地进入和离开所述一次性盒的泵室的透析液的体积控制; 可操作地连接到盒接口的加热器; 以及可操作地连接到加热器的控制器，以便使加热器将盒接口的至少一部分加热到所需温度。
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公开(公告)号：US08597230B2
公开(公告)日：2013-12-03
申请号：US13308775
申请日：2011-12-01
IPC分类号： A61M1/00
CPC分类号： A61M1/28 , A61M1/1656 , A61M1/166 , A61M1/1668 , A61M1/167 , A61M1/282 , A61M1/284 , A61M1/287 , A61M1/288 , A61M2205/122 , A61M2205/128 , A61M2205/505 , A61M2205/70 , A61M2209/084 , Y10S604/905 , Y10T29/49826
摘要： A dialysis system is disclosed including an autoconnection mechanism. The autoconnection mechanism in an embodiment is configured such that (i) a tip protector remover is translated in a first direction towards a plurality of supply line connectors, (ii) the tip protector remover is locked to each of a plurality of supply line tip protectors connected to the plurality of supply line connectors, (iii) the tip protector remover is translated in a second direction away from the plurality of supply line connectors to remove the plurality of supply line tip protectors from the supply line connectors, the tip protector remover is translated in a third direction different from the first and second directions, and (v) solution line connectors are translated towards the supply line connectors to connect each of the solution line connectors to one of the supply line connectors.
摘要翻译： 公开了一种透析系统，包括自动连接机构。 一个实施例中的自动连接机构被配置为使得（i）尖端保护器移除器沿着第一方向朝向多个供应线连接器平移，（ii）尖端保护器移除器被锁定到多个供应线尖端保护器 连接到多个供应线连接器，（iii）尖端保护器去除器在远离多个供应线连接器的第二方向上平移以从供应线连接器去除多个供应线尖端保护器，尖端保护器去除器是 在不同于第一和第二方向的第三方向上转换，并且（v）溶液线连接器朝向供应线连接器平移，以将每个溶液管线连接器连接到一个供应线连接器。
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公开(公告)号：US08512553B2
公开(公告)日：2013-08-20
申请号：US11773634
申请日：2007-07-05
CPC分类号： A61M1/282 , A61M1/1039 , A61M1/16 , A61M1/1601 , A61M1/1603 , A61M1/1611 , A61M1/1639 , A61M1/168 , A61M1/1682 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1694 , A61M1/1696 , A61M1/28 , A61M1/284 , A61M1/288 , A61M1/30 , A61M1/34 , A61M1/3417 , A61M1/3427 , A61M1/3431 , A61M1/3437 , A61M1/3444 , A61M2205/12 , A61M2205/128 , A61M2205/3331 , A61M2205/3344 , A61M2205/3368 , A61M2205/3379 , A61M2205/50 , A61M2205/502 , A61M2210/1017
摘要： A dialysis system includes: (i) a dialysate pump; (ii) a patient line having a connector configured to be attached to a peritoneal patient part; (iii) an extracorporeal circuit; (iv) a blood pump in fluid communication with the extracorporeal circuit; (v) a blood filter in fluid communication with the extracorporeal circuit; and (vi) a control unit configured and arranged to selectively perform a therapy which (a) the blood pump is deactivated and the dialysate pump is caused to pump dialysate through the patient line or (b) the blood pump is activated to pump blood to the blood filter and the dialysate pump is caused to pump dialysate to the filter/extracorporeal circuit and/or remove fluid from the filter.
摘要翻译： 透析系统包括：（i）透析泵; （ii）具有被配置为附接到腹膜患者部分的连接器的患者线; （iii）体外循环; （iv）与体外回路流体连通的血泵; （v）与体外循环流体连通的血液过滤器; （vi）控制单元，其配置和布置成选择性地执行（a）所述血液泵被停用并且所述透析液泵通过所述患者管线泵送透析液的治疗，或者（b）所述血液泵被激活以将血液泵送到 使血液过滤器和透析液泵将透析液泵送到过滤器/体外回路和/或从过滤器去除流体。
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