公开(公告)号：US07328722B2

公开(公告)日：2008-02-12

申请号：US11297667

申请日：2005-12-07

Applicant: Collin A. Rich ,  Steven M. Martin

Inventor： Collin A. Rich ,  Steven M. Martin

IPC: F16L55/04

CPC classification number: F15B1/021 ,  F04B43/12 ,  F15B1/10 ,  F15B21/008 ,  F15B2201/205 ,  F15B2201/215 ,  F15B2201/3151 ,  G01N15/1404 ,  Y10T137/3118 ,  Y10T137/7792

Abstract: A pulsation attenuator for a fluidic system with a fluidic pump. The pulsation attenuator includes a fluidic channel, a first fluidic device adapted to attenuate pulsations with a shallow rolloff slope, and a second fluidic device adapted to attenuate pulsations with a shallow rolloff slope. The first fluidic device and the second fluidic device are connected to the fluidic channel such that they cooperatively attenuate pulsations with a steep rolloff slope. Preferably, the first fluidic device includes a first fluidic resistor and a first fluidic capacitor, and the second fluidic device includes a second fluidic resistor and a second fluidic capacitor. Preferably, the pulsation attenuator is arranged, similar a second-order low-pass filter, in the following order: (1) first fluidic resistor, (2) first fluidic capacitor, (3) second fluidic resistor, and (4) second fluidic capacitor.

Abstract translation: 一种具有流体泵的流体系统的脉动衰减器。 脉动衰减器包括流体通道，适于衰减具有浅滚降斜率的脉动的第一流体装置，以及适于以浅滚降斜率衰减脉动的第二流体装置。 第一流体装置和第二流体装置连接到流体通道，使得它们以陡峭的滚降斜率协同地衰减脉动。 优选地，第一流体装置包括第一流体电阻器和第一流体电容器，并且第二流体装置包括第二流体电阻器和第二流体电容器。 优选地，按照以下顺序将脉动衰减器类似于二阶低通滤波器：（1）第一流体电阻器，（2）第一流体电容器，（3）第二流体电阻器，和（4）第二流体电阻器 电容器。

公开(公告)号：US20070243106A1

公开(公告)日：2007-10-18

申请号：US11736412

申请日：2007-04-17

Applicant: Collin A. Rich

Inventor： Collin A. Rich

IPC: G01N33/00

CPC classification number: G01N15/1404 ,  G01N2015/1409 ,  Y10T436/115831

Abstract: The fluidic system of the preferred embodiment includes a sheath pump to pump sheath fluid from a sheath container into an interrogation zone, a sheath volume measurement device to measure the fluid in the sheath container, a waste pump to pump the sheath fluid and a sample fluid as waste fluid from the interrogation zone into a waste container, and a waste volume measurement device to measure the fluid in the waste container. The system also includes a controller connected to the sheath pump, the waste pump, and the volume measurement devices. The sheath pump and/or the waste pump draw sample fluid from a sample container into the interrogation zone, which functions to provide a location for the fluidic system and an optical system of the flow cytometer to cooperatively facilitate the analysis of the sample fluid.

Abstract translation: 优选实施例的流体系统包括鞘套泵，以将护套流体从护套容器泵送到询问区域中;护套体积测量装置，用于测量护套容器中的流体;泵送护套流体的废泵和样品流体 作为从询问区到废物容器的废液，以及用于测量废物容器中的流体的废物体积测量装置。 该系统还包括连接到护套泵，废水泵和体积测量装置的控制器。 护套泵和/或废液泵将样品流体从样品容器抽入询问区，其功能是提供流体系统的位置和流式细胞计数器的光学系统，以便协调地促进样品流体的分析。

公开(公告)号：US06968743B2

公开(公告)日：2005-11-29

申请号：US10054331

申请日：2002-01-22

Applicant: Collin A. Rich ,  Yafan Zhang ,  Nader Najafi

Inventor： Collin A. Rich ,  Yafan Zhang ,  Nader Najafi

IPC: A61B5/00 ,  A61B5/0215 ,  A61B5/027 ,  G01L9/12

CPC classification number: A61B5/6852 ,  A61B5/0031 ,  A61B5/02028 ,  A61B5/0215 ,  A61B5/027 ,  A61B5/0295 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/4839 ,  A61B5/6862 ,  A61B5/6876 ,  A61B5/6882 ,  A61B2562/028

Abstract: The present invention defines an implantable microfabricated sensor device for measuring a physiologic parameter of interest within a patient. The sensor device includes a substrate and a sensor, integrally formed with the substrate, that is responsive to the physiologic parameter of interest. At least one conductive path is integrally formed with said substrate and coupled to the sensor. Connected to the conductive path is an active circuit. The active circuit is further electrically connected to the sensor.

Abstract translation: 本发明定义了一种用于测量患者内感兴趣的生理参数的可植入微制造传感器装置。 传感器装置包括与基底一体形成的基底和传感器，该传感器响应感兴趣的生理参数。 至少一个导电路径与所述衬底一体地形成并且耦合到传感器。 连接到导电通路是一个有源电路。 有源电路进一步电连接到传感器。