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76 条记录 (耗时 0.028 秒)

    Bicycle wheel securing structure
    61.
    发明授权
    Bicycle wheel securing structure 有权
    自行车轮固定结构

    公开(公告)号：US08052225B2

    公开(公告)日：2011-11-08

    申请号：US12968468

    申请日：2010-12-15

    申请人： Jun Inoue ,  Takanori Kanehisa

    发明人： Jun Inoue ,  Takanori Kanehisa

    IPC分类号： B60B27/00

    CPC分类号： B62K25/02 ,  B62K23/06 ,  B62K2206/00 ,  B62M25/04

    摘要： A bicycle wheel securing structure includes a bicycle fork, an adapter and a holding member. The bicycle fork has two axle support portions that are spaced apart for receiving a bicycle hub therebetween. The adapter is disposed in an adapter receiving bore in one of the axle support portions. The adapter includes a threaded axle mounting opening. The holding member is operatively coupled between the adapter and the one of the axle support portions with the adapter. The holding member prevents both rotational movement of the adapter with respect to the bicycle fork and axial movement of the adapter with respect to the bicycle fork along an axis of the axle mounting opening when the holding member is in a retaining position. The adapter is rotatable within the adapter receiving bore without moving axially with respect to the bicycle fork when the holding member is in a releasing position.

    摘要翻译： 自行车车轮固定结构包括自行车叉，适配器和保持构件。 自行车叉具有间隔开的用于在其间接纳自行车轮毂的两个轴支撑部分。 适配器设置在一个轴支撑部分中的适配器接收孔中。 适配器包括一个螺纹轴安装孔。 保持构件通过适配器可操作地联接在适配器和轴支撑部分中的一个之间。 当保持构件处于保持位置时，保持构件防止适配器相对于自行车叉的旋转运动和适配器相对于自行车叉沿着轴安装开口的轴线的轴向运动。 当保持构件处于释放位置时，适配器可在适配器容纳孔内旋转，而不相对于自行车叉轴向移动。

    Bicycle wheel securing structure
    62.
    发明授权
    Bicycle wheel securing structure 有权

    公开(公告)号：US08042881B2

    公开(公告)日：2011-10-25

    申请号：US12268469

    申请日：2008-11-11

    申请人： Jun Inoue ,  Takanori Kanehisa

    发明人： Jun Inoue ,  Takanori Kanehisa

    IPC分类号： B60B27/00

    CPC分类号： B62K25/02 ,  B62K23/06 ,  B62K2206/00 ,  B62M25/04

    摘要： A bicycle wheel securing structure includes a bicycle fork, an adapter and a holding member. The bicycle fork has two axle support portions that are spaced apart for receiving a bicycle hub therebetween. The adapter is disposed in an adapter receiving bore in one of the axle support portions. The adapter includes a threaded axle mounting opening. The holding member is operatively coupled between the adapter and the one of the axle support portions with the adapter. The holding member prevents both rotational movement of the adapter with respect to the bicycle fork and axial movement of the adapter with respect to the bicycle fork along an axis of the axle mounting opening when the holding member is in a retaining position. The adapter is rotatable within the adapter receiving bore without moving axially with respect to the bicycle fork when the holding member is in a releasing position.

    METHOD FOR DETECTING NEUROBLASTOMA
    63.
    发明申请
    METHOD FOR DETECTING NEUROBLASTOMA 有权
    检测神经元的方法

    公开(公告)号：US20100105868A1

    公开(公告)日：2010-04-29

    申请号：US12568569

    申请日：2009-09-28

    申请人： Johji Inazawa ,  Issei Imoto ,  Jun Inoue

    发明人： Johji Inazawa ,  Issei Imoto ,  Jun Inoue

    IPC分类号： C07K14/435 ,  C12Q1/68 ,  C12N5/02 ,  C07H21/04

    CPC分类号： G01N33/57407 ,  A61K38/00 ,  C12Q1/6886 ,  C12Q2600/154

    摘要： The present invention is intended to provide a means for judging the malignancy of neuroblastoma and the progress of spontaneous regression thereof. The present invention provides a method for detecting cancer which comprises detecting activation or inactivation of the lysosomal-associated protein multispanning transmembrane 5 (LAPTM5) gene and amplification of the MYCN gene in a specimens to evaluate the malignancy of the specimens and the progress of spontaneous regression.

    摘要翻译： 本发明旨在提供一种判断神经母细胞瘤的恶性程度及其自发消退的方法。 本发明提供一种检测癌症的方法，其包括检测样品中溶酶体相关蛋白多能跨膜5（LAPTM5）基因的活化或失活以及MYCN基因的扩增，以评估标本的恶性程度和自发回归的进展 。

    Image processing device
    65.
    发明授权
    Image processing device 失效

    公开(公告)号：US07586522B2

    公开(公告)日：2009-09-08

    申请号：US11704467

    申请日：2007-02-09

    申请人： Jun Inoue ,  Osamu Inagaki ,  Shinichi Nakajima ,  Hiroki Shibasaki

    发明人： Jun Inoue ,  Osamu Inagaki ,  Shinichi Nakajima ,  Hiroki Shibasaki

    IPC分类号： H04N5/228 ,  H04N9/09 ,  H04N5/225

    CPC分类号： H04N7/066 ,  H04N5/217 ,  H04N5/772 ,  H04N9/7973 ,  H04N9/8042

    摘要： In short, the image processing device for obtaining a single image by using a plurality of image-pickup elements comprises a plurality of image-pickup signal processing circuits that are provided for each of the image-pickup elements, an image arrangement conversion circuit which converts the read-out order of the images corresponding to the respective image-pickup elements that are output from the image-pickup signal processing circuits, an image splitting processing circuit for performing image splitting on the image that is output from the image arrangement conversion circuit, an image processing circuit for performing image processing in parallel on each of the split images, and an image compression circuit for compressing in parallel each of the split images that are output from the image processing circuit.

    Drug composition comprising dipeptidyl aldehyde derivative
    66.
    发明授权
    Drug composition comprising dipeptidyl aldehyde derivative 失效
    药物组合物包含二肽基醛衍生物

    公开(公告)号：US07572833B2

    公开(公告)日：2009-08-11

    申请号：US10415295

    申请日：2001-09-27

    申请人： Jun Inoue ,  Masazumi Yamaguchi

    发明人： Jun Inoue ,  Masazumi Yamaguchi

    IPC分类号： A61K31/18

    CPC分类号： A61K47/28 ,  A61K9/0019 ,  A61K9/0048 ,  A61K9/127 ,  A61K9/4858 ,  A61K31/18 ,  A61K31/404 ,  A61K47/02 ,  A61K47/24 ,  A61K47/54

    摘要： The present invention provides a preparation containing a compound of the formula (I) wherein R1 is an alkyl group having 1 to 4 carbon atoms or an optionally substituted aryl group having 6 to 10 carbon atoms; R2 and R3 are the same or different and each is hydrogen or an alkyl group having 1 to 4 carbon atoms, or R2 and R3 in combination form a ring having 3 to 7 carbon atoms; and R4 is a lower alkyl group optionally substituted by aryl, cycloalkyl or aromatic heterocyclic residue, or a pharmaceutically acceptable salt thereof together with a lipid. The preparation shows improved stability and improved absorption and penetration into tissue.

    摘要翻译： 本发明提供含有式（I）的化合物的制备方法，其中R 1为碳原子数为1〜4的烷基或可具有取代基的碳原子数6〜10的芳基。 R2和R3相同或不同，各自为氢或具有1至4个碳原子的烷基，或R2和R3组合形成具有3至7个碳原子的环; 并且R 4是任选被芳基，环烷基或芳族杂环残基或其药学上可接受的盐与脂质取代的低级烷基。 该制剂显示改进的稳定性和改善的吸收和渗透到组织中。