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91 条记录 (耗时 0.121 秒)

    RAKE HEAD
    63.
    发明申请
    RAKE HEAD 审中-公开
    RAKE头

    公开(公告)号：US20100218476A1

    公开(公告)日：2010-09-02

    申请号：US12548244

    申请日：2009-08-26

    申请人： Gilles Gosselin

    发明人： Gilles Gosselin

    IPC分类号： A01D7/00

    CPC分类号： A01D7/10

    摘要： The present invention relates to a rake head, typically for a lawn or garden rake, which optimizes the gathering of matter, facilitates collecting and lifting the gathered matter and also serves as a standard rake. There is provided a rake head adapted for being mounted at an end of a handle and including a first fork having a handle connector for attaching the first fork to the handle, and further including a second fork having a U-shaped connector for removably and radially mounting the second fork with respect to the first fork, the second fork being movable between an unassembled position wherein the second fork is detached from the first fork, and an assembled position wherein the second fork is fixedly disposed in parallel with respect to the first fork.

    摘要翻译： 本发明涉及一种通常用于草坪或花园耙的耙头，其优化了物料收集，便于收集和提升收集的物质，并且还用作标准耙子。 提供了一种适于安装在手柄的端部的前刀头，包括具有手柄连接器的第一叉，用于将第一叉连接到手柄，并且还包括具有U形连接器的第二叉，用于可移除地和径向地 相对于第一叉安装第二叉，第二叉可在第二叉与第一叉分离的未组装位置和组装位置之间移动，其中第二叉相对于第一叉固定地平行设置 。

    2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
    67.
    发明申请
    2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections 有权
    2'-C-甲基-3'-O-L-缬氨酸酯呋喃核糖基胞苷用于治疗黄病毒科感染

    公开(公告)号：US20070275883A1

    公开(公告)日：2007-11-29

    申请号：US11516928

    申请日：2006-09-06

    申请人： Jean-Pierre Sommadossi ,  Paolo LaColla ,  Gilles Gosselin

    发明人： Jean-Pierre Sommadossi ,  Paolo LaColla ,  Gilles Gosselin

    IPC分类号： A61K31/7072 ,  A61K31/7068

    CPC分类号： A61K31/7068 ,  A61K31/7072 ,  A61K45/06 ,  A61K2300/00

    摘要： The 3′-L-valine ester of β-D-2′-C-methyl-ribofuranosyl cytidine provides superior results against flaviviruses and pestiviruses, including hepatitis C virus. Based on this discovery, compounds, compositions, methods and uses are provided for the treatment of flaviviridae, including HCV, that include the administration of an effective amount of val-mCyd or its salt, ester, prodrug or derivative, optionally in a pharmaceutically acceptable carrier. In an alternative embodiment, val-mCyd is used to treat any virus that replicates through an RNA-dependent RNA polymerase.

    摘要翻译： β-D-2'-C-methyl-ribofuranosyl cytidine的3'-L-缬氨酸酯提供了对黄病毒和瘟病毒（包括丙型肝炎病毒）的优异结果。 基于这一发现，提供了化合物，组合物，方法和用途，用于治疗黄病毒科，包括HCV，其包括施用有效量的val-mCyd或其盐，酯，前药或衍生物，任选地在药学上可接受的 载体 在替代实施方案中，val-mCyd用于治疗通过RNA依赖性RNA聚合酶复制的任何病毒。