Preserving patient specific data in implantable pulse generator systems
    63.
    发明授权
    Preserving patient specific data in implantable pulse generator systems 有权
    在植入式脉冲发生器系统中保存患者特定数据

    公开(公告)号:US06285909B1

    公开(公告)日:2001-09-04

    申请号:US09321254

    申请日:1999-05-27

    IPC分类号: A61N1362

    CPC分类号: A61N1/37252 A61N1/37288

    摘要: A method and a system for preserving patient specific data in implantable pulse generator systems. A communication link is established with a first implantable pulse generator. Electronic cardiac data contained within the first implantable pulse generator is retrieved through the communication link. The electronic cardiac data is then electronically downloaded to a second implantable pulse generator. Prior to downloading, the electronic cardiac data can be formatted into a format compatible with the second implantable pulse generator.

    摘要翻译: 一种用于在植入式脉冲发生器系统中保存患者特定数据的方法和系统。 建立与第一可植入脉冲发生器的通信链路。 通过通信链路检索包含在第一可植入脉冲发生器内的电子心脏数据。 然后将电子心脏数据电子下载到第二可植入脉冲发生器。 在下载之前,电子心脏数据可以被格式化成与第二可植入脉冲发生器兼容的格式。

    Cardiac rhythm management system with arrhythmia prediction and prevention
    64.
    发明授权
    Cardiac rhythm management system with arrhythmia prediction and prevention 有权
    心律失常预防与心律失常管理系统

    公开(公告)号:US06272377B1

    公开(公告)日:2001-08-07

    申请号:US09411345

    申请日:1999-10-01

    IPC分类号: A61B50468

    摘要: A cardiac rhythm management system predicts when an arrhythmia will occur and in one embodiment invokes a therapy to prevent or reduce the consequences of the arrhythmia. A cardiac arrhythmia trigger/marker is detected from a patient, and based on the trigger/marker, the system estimates a probability of a cardiac arrhythmia occurring during a predetermined future time interval. The system provides a list of triggers/markers, for which detection values are recurrently obtained at various predetermined time intervals. Based on detection values and conditional probabilities associated with the triggers/markers, a probability estimate of a future arrhythmia is computed. An arrhythmia prevention therapy is selected and activated based on the probability estimate of the future arrhythmia.

    摘要翻译: 心律管理系统预测何时发生心律失常,并且在一个实施例中调用治疗以预防或减少心律失常的后果。 从患者检测到心律失常触发/标记,并且基于触发/标记,系统估计在预定的未来时间间隔期间发生心律失常的概率。 该系统提供了一个触发/标记列表,为各种预定时间间隔循环获得检测值。 基于与触发/标记相关联的检测值和条件概率,计算未来心律失常的概率估计。 基于对未来心律失常的概率估计,选择并激活心律失常预防疗法。

    Method and apparatus for treating ventricular fibrillation using electrogram features
    65.
    发明授权
    Method and apparatus for treating ventricular fibrillation using electrogram features 失效
    使用电描记图特征治疗心室颤动的方法和装置

    公开(公告)号:US06251125B1

    公开(公告)日:2001-06-26

    申请号:US09053115

    申请日:1998-04-01

    IPC分类号: A61N139

    CPC分类号: A61N1/3962

    摘要: A method and system for ventricular defibrillation by coordinating the delivery of defibrillation shocks with sensed ventricular fibrillation complexes in a way which improves the probability of success of the defibrillation shock. Ventricular electrical activity is monitored in two ventricular locations during ventricular fibrillation to detect coarse ventricular fibrillation complexes and contractions of the ventricular cardiac tissue. The defibrillation shock is delivered in coordination with the occurrence of coarse ventricular fibrillation complexes and the contractions of ventricular cardiac tissue, and specifically to occur on the up-slope portion thereof, for optimal probability of success.

    摘要翻译: 通过以提高除颤休克成功概率的方式协调将感染的心室颤动复合物递送除颤电击的心室除颤的方法和系统。 在心室纤维性颤动期间,在两个心室位置监测心室电活动,以检测心室心脏组织的粗略心室颤动复合物和收缩。 伴随发生粗心室颤动复合物和心室心脏组织的收缩,特别是在其上坡部分发生除颤休克,以获得最佳的成功概率。

    Controlled release drug delivery
    66.
    发明授权
    Controlled release drug delivery 有权
    控制释放药物递送

    公开(公告)号:US06168801A

    公开(公告)日:2001-01-02

    申请号:US09272428

    申请日:1999-03-19

    IPC分类号: A61F202

    CPC分类号: A61K9/0024

    摘要: Biologically active materials are provided in a cylindrical carrier medium with better control over the rate of delivery and length of time of delivery by providing a carrier having dissolved or dispersed therein at least two compounds having a common biologically active nucleus, but with different solubility parameters. The combination of the two different variants of the same drug with different solubility parameters provides the material with control over the rate of release of the compounds (by varying the proportions of the variants) and most importantly, extending the useful life of the device by enabling release of effective levels of the compounds over a longer period of time. The cylindrical carrier medium, comprised of silicone, further includes a tail, a skirt, or a rate-limiting membrane.

    摘要翻译: 生物活性材料提供在圆柱形载体介质中,通过提供具有溶解或分散在其中的至少两种具有共同的生物活性核,但具有不同溶解度参数的化合物的载体,可以更好地控制输送速率和输送时间。 具有不同溶解度参数的相同药物的两种不同变体的组合提供了材料对化合物释放速率的控制(通过改变变体的比例),最重要的是通过使得能够延长器件的使用寿命 在更长的时间内释放有效含量的化合物。 由硅树脂构成的圆柱形载体介质还包括尾部,裙部或限速膜。

    Implantable conformal coil patch electrode with multiple conductive
elements for cardioversion and defibrillation
    67.
    发明授权
    Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation 失效
    可植入的保形线圈贴片电极,具有多个用于心脏复律和除颤的导电元件

    公开(公告)号:US6152955A

    公开(公告)日:2000-11-28

    申请号:US240396

    申请日:1999-01-29

    IPC分类号: A61N1/05 A61N1/39

    CPC分类号: A61N1/0587

    摘要: Body-implantable leads with open, unbacked (uninsulated) electrode structures having electrical discharge surfaces formed by conductive elements, such as mesh and braid, and preferably coils. The electrode structures can be classified by pattern: (1) loops, (2) linear arrays and (3) radial arrays. The electrodes are located on or near the epicardial surface of the right and left heart.

    摘要翻译: 具有开放,未背衬(未绝缘)电极结构的体内可植入引线,其具有由诸如网和编织物的导电元件形成的放电表面,并且优选线圈。 电极结构可以通过图案分类:(1)环,(2)线性阵列和(3)径向阵列。 电极位于右心左心外表面上或附近。

    Implantable conformal coil electrode with multiple conductive elements
for cardioversion and defibrillation
    68.
    发明授权
    Implantable conformal coil electrode with multiple conductive elements for cardioversion and defibrillation 失效
    可植入的保形线圈电极,具有多个用于心脏复律和除颤的导电元件

    公开(公告)号:US6032079A

    公开(公告)日:2000-02-29

    申请号:US240447

    申请日:1999-01-29

    IPC分类号: A61N1/05 A61N1/39

    CPC分类号: A61N1/0587

    摘要: Body-implantable leads with open, unbacked (uninsulated) electrode structures having electrical discharge surfaces formed by conductive elements, such as mesh and braid, and preferably coils. The electrode structures can be classified by pattern: (1) loops, (2) linear arrays and (3) radial arrays. The electrodes are located on or near the epicardial surface of the right and left heart.

    摘要翻译: 具有开放,未背衬(未绝缘)电极结构的体内可植入引线,其具有由诸如网和编织物的导电元件形成的放电表面,并且优选线圈。 电极结构可以通过图案分类:(1)环,(2)线性阵列和(3)径向阵列。 电极位于右心左心外表面上或附近。