公开(公告)号：US07287995B2

公开(公告)日：2007-10-30

申请号：US10983266

申请日：2004-11-08

申请人： Paul M. Stein ,  Timothy W. Holleman ,  Andrew J. Ries ,  Harry Schroder ,  Jordon D. Honeck ,  John L. Sommer ,  Vicki L. Bjorklund

发明人： Paul M. Stein ,  Timothy W. Holleman ,  Andrew J. Ries ,  Harry Schroder ,  Jordon D. Honeck ,  John L. Sommer ,  Vicki L. Bjorklund

IPC分类号： H01R27/00

CPC分类号： A61N1/3752 ,  A61N1/056 ,  A61N1/0573 ,  A61N2001/0578 ,  A61N2001/0585 ,  H01R13/5224 ,  H01R24/58 ,  H01R31/06 ,  H01R2107/00 ,  H01R2201/12

摘要： A lead connector arrangement includes a non-cylindrically shaped connector pin coupled to a lead conductor and a connector sleeve assembly for receiving the non-cylindrically shaped connector pin. The connector sleeve assembly includes an insert with an axial bore formed therein that complements the shape of the non-cylindrical connector pin. According to one embodiment, the non-cylindrical connector pin may be provided in the form of a triangular, square, rectangular, or hexagonal shape. The axial bore has a complimentary shape to receive the connector pin. When the connector pin is threaded through the connector sleeve assembly using a pull-wire device, the pull-wire device may be unscrewed from the connector pin without causing axial rotation of the lead conductor when the connector pin is fully inserted within the axial bore.

摘要翻译： 引线连接器装置包括耦合到引线导体的非圆柱形连接器引脚和用于接收非圆柱形连接器引脚的连接器套筒组件。 连接器套筒组件包括插入件，其中形成有轴向孔，其与非圆柱形连接器销的形状相互补充。 根据一个实施例，非圆柱形连接器销可以以三角形，正方形，矩形或六边形的形式提供。 轴向孔具有接收连接器针的互补形状。 当连接器针通过拉线装置穿过连接器套筒组件时，当连接器插针完全插入轴向孔中时，拉线装置可以从连接器销拧下而不导致引线导体的轴向旋转。

公开(公告)号：US07254450B2

公开(公告)日：2007-08-07

申请号：US10918060

申请日：2004-08-13

申请人： Mark A. Christopherson ,  Nancy Perry Pool ,  John L. Sommer ,  Eric Bonde

发明人： Mark A. Christopherson ,  Nancy Perry Pool ,  John L. Sommer ,  Eric Bonde

IPC分类号： A61N1/08

CPC分类号： A61N1/05 ,  A61N1/056

摘要： The invention is directed to lead configurations for sensors that allow for less invasive sensor replacement procedures. In one configuration, a sensor lead assembly includes an outer lead body and an inner lead including a sensor such as an electrochemical glucose sensor. The inner lead can be positioned in an inner conduit of the outer lead body. The outer lead body may be substantially permanently implanted in the patient, and the inner lead can be implanted through the inner conduit of the outer lead body. Once the sensor of the inner lead has worn out or otherwise exhausted its useful life, the inner lead can be removed, and a new inner lead can be implanted in place of the old inner lead.

摘要翻译： 本发明涉及允许较少侵入性的传感器更换程序的传感器的引线配置。 在一种配置中，传感器引线组件包括外引线体和包括诸如电化学葡萄糖传感器的传感器的内引线。 内引线可以定位在外引线体的内导管中。 外引线体可以基本上永久地植入患者体内，并且内引线可以通过外引线体的内导管植入。 一旦内部引线的传感器已经磨损或以其他方式耗尽其使用寿命，内部引线可以被去除，并且可以将新的内部引线植入代替旧的内部引线。

公开(公告)号：US07067765B2

公开(公告)日：2006-06-27

申请号：US10923925

申请日：2004-08-23

申请人： Ryan T. Bauer ,  Daniel R. Pavlik ,  John L. Sommer

发明人： Ryan T. Bauer ,  Daniel R. Pavlik ,  John L. Sommer

IPC分类号： B23K26/38

CPC分类号： A61N1/05 ,  Y10T29/49174 ,  Y10T29/49194

摘要： A method for forming an electrically active surface for a medical electrical lead includes the steps of inserting a conductor coil into a shroud that includes an opening, lifting an end of at least one filar of a plurality of filars forming the coil out through the opening, and removing a layer of insulation from about the end of the at least one filar by means of laser ablation.

摘要翻译： 用于形成用于医用电线的电活性表面的方法包括以下步骤：将导体线圈插入到包括开口的护罩中，通过所述开口将形成所述线圈的多个丝状物的至少一个丝线的端部提起， 以及通过激光烧蚀从所述至少一根丝束的端部移除绝缘层。

公开(公告)号：US06675049B2

公开(公告)日：2004-01-06

申请号：US09907308

申请日：2001-07-17

申请人： David L. Thompson ,  Steven D. Goedeke ,  Gregory J. Haubrich ,  Ryan Cobian ,  Eric Bonde ,  John L. Sommer ,  Jonathan Werder ,  Nels Nerison ,  Eric V. Blaha

发明人： David L. Thompson ,  Steven D. Goedeke ,  Gregory J. Haubrich ,  Ryan Cobian ,  Eric Bonde ,  John L. Sommer ,  Jonathan Werder ,  Nels Nerison ,  Eric V. Blaha

IPC分类号： A61N136

CPC分类号： A61N1/37252 ,  A61B5/0031 ,  A61B2560/0219 ,  A61N1/025 ,  A61N1/05 ,  A61N1/37223 ,  A61N1/3752 ,  A61N2001/0585

摘要： An automated identification and configuration system for use with an implantable medical device (IMD) is disclosed. The system includes a first communication circuit that is attached to, or otherwise carried by, a detachable component associated with the IMD such as a medical lead. The communication circuit stores data such as model numbers, serial numbers, technical data, and/or calibration information that describes the additional component. This information may be transferred by the first communications circuit to a second communications circuit that is external to the additional component. This transferred data can be used to automatically configure the internal circuitry and connection functions of the IMD to properly interface with, and support, the additional component. For example, the data can be used to automatically adjust amplifier gains or other sensor circuitry, or to configure a connector block to properly couple to the component. The data may further be entered into a patient record on an external programmer, or may be transferred to a central storage location to be generally accessible to health care providers. In one embodiment, the first communication circuit is a passive RF transponder. This first communication circuit may include a receiver as well as a transmitter to allow the circuit to programmably receive data at the time of component manufacture.

公开(公告)号：US06572543B1

公开(公告)日：2003-06-03

申请号：US09589002

申请日：2000-06-06

申请人： Mark A. Christopherson ,  John L. Sommer ,  Johann J. Neisz

发明人： Mark A. Christopherson ,  John L. Sommer ,  Johann J. Neisz

IPC分类号： A61B500

CPC分类号： A61B5/03 ,  A61B5/7207 ,  A61N1/3601

摘要： An implantable sensing device includes a sensing element and a mounting element. The mounting element has a first end and a second end with a longitudinal axis therethrough. The sensing element is positioned at the first end of the mounting element with the mounting element having a length that is adjustable along the longitudinal axis. The mounting element includes a sleeve having a first open end and a second open end with the longitudinal axis therethrough. The sensing element is positioned in the second open end and includes a lead body connected thereto extending through the second open end. The sleeve includes an outer sleeve member coupled for adjustment along the longitudinal axis with respect to an inner sleeve member. Further, the mounting element may include a flexible element about the first open end extending outwardly relative to the longitudinal axis and a flange element extending outwardly relative to the longitudinal axis from at least a portion of the second end. The device can be implanted in a bone with the flange element and the flexible element for direct or indirect contact with the anterior and posterior surface of the bone. A method of implanting the sensor includes providing a sensing element and drilling a hole in a bone. The hole extends to the intrathoracic cavity. The sensing element is inserted into the hole and positioned in communication with a region in the intrathoracic cavity. The hole is drilled in the manubrium. When the flexible element is inserted into the hole, the flexible element about the first open end collapses towards the longitudinal axis and when the sensor mounting assembly is removed from the hole, the flexible element collapses towards the longitudinal axis during removal. Methods for providing stimulation of a patient to treat respiratory disorders using the sensor are also provided as are stimulation systems for providing stimulation of a patient to treat respiratory disorders.

公开(公告)号：US08509893B2

公开(公告)日：2013-08-13

申请号：US12913354

申请日：2010-10-27

申请人： Yong-Fu Xiao ,  John L. Sommer ,  Scott J. Brabec ,  Lepeng Zeng ,  Jon F. Urban

发明人： Yong-Fu Xiao ,  John L. Sommer ,  Scott J. Brabec ,  Lepeng Zeng ,  Jon F. Urban

IPC分类号： A61N1/372

CPC分类号： A61N1/3622 ,  A61N1/36564 ,  A61N1/368

摘要： Various techniques for delivering atrial pacing and supraventricular stimulation to achieve a desired ventricular rate and/or cardiac output are described. One example method described includes delivering a pacing signal configured to cause an atrial depolarization to a heart of a patient, wherein the atrial depolarization results in an associated refractory period during the cardiac cycle, and delivering a signal to a supraventricular portion of the heart of the patient subsequent to the atrial refractory period and during a ventricular refractory period of the cardiac cycle.

摘要翻译： 描述用于递送心房起搏和室上性刺激以实现期望的心室率和/或心输出量的各种技术。 所描述的一个示例性方法包括递送起搏信号，所述起搏信号被配置成对患者的心脏进行心房去极化，其中所述心房去极化在心脏周期期间导致相关联的不应期，并将信号传递到心脏的心脏的室上部分 患者在心房不良期后和心动周期心室不应期。

公开(公告)号：US20130006332A1

公开(公告)日：2013-01-03

申请号：US13616300

申请日：2012-09-14

申请人： John L. Sommer ,  David Wayne Bourn ,  Mark T. Marshall ,  Michael D. Eggen ,  Gabriela C. Miyazawa

发明人： John L. Sommer ,  David Wayne Bourn ,  Mark T. Marshall ,  Michael D. Eggen ,  Gabriela C. Miyazawa

IPC分类号： A61N1/37 ,  A61N1/36

CPC分类号： A61N1/36514 ,  A61N1/056 ,  A61N1/36114 ,  A61N1/36185 ,  A61N1/3684 ,  A61N1/3686 ,  A61N2001/0585

摘要： A medical system comprises a plurality of electrodes; at least one sensor configured to output at least one signal based on at least one physiological parameter of a patient; and a processor. The processor is configured to control delivery of stimulation to the patient using a plurality of electrode configurations. Each of the electrode configurations comprises at least one of the plurality of electrodes. For each of the electrode configurations, the processor is configured to determine a first response of target tissue to the stimulation based on the signals, and a second response of non-target tissue to the stimulation based on the signals. The processor is also configured to select at least one of the electrode configurations for delivery of stimulation to the patient based on the first and second responses for the electrode configurations. As examples, the target tissue may be a left ventricle or vagus nerve.

公开(公告)号：US08340783B2

公开(公告)日：2012-12-25

申请号：US12825647

申请日：2010-06-29

申请人： John L. Sommer ,  Kenneth C. Gardeski ,  Xiaonan Shen ,  Jon D. Schell

发明人： John L. Sommer ,  Kenneth C. Gardeski ,  Xiaonan Shen ,  Jon D. Schell

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/05 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/086

摘要： An implantable lead including a lead body including an outer surface, a proximal end, a distal end, and at least one electrode; an electrically insulating member that extends axially over a first portion of the outer surface of the lead body between the proximal end and distal end, the electrically insulating member defining at least one aperture that exposes a first portion of the at least one electrode when in a first position over the lead body; and a reinforcement member formed at least partially of a different material than the insulating member and coupled to the insulating member, the reinforcement member extending axially over the outer surface of the lead body between the insulating member and proximal end. The reinforcement member may be configured to transfer at least one of a radial or axial force from a proximal portion of the reinforcement member to the insulating member, wherein the at least one of radial or axial force transferred to the insulating member is sufficient to move the insulating member over the outer surface of the lead body. In some examples, the lead may further include a deployable lobe member configured to anchor the reinforcement member and insulating member adjacent a tissue site within a patient.

摘要翻译： 一种可植入引线，包括：引线本体，其包括外表面，近端，远端和至少一个电极; 电绝缘构件，其在所述近端和远端之间轴向延伸到所述引线本体的外表面的第一部分上方，所述电绝缘构件限定在至少一个孔处暴露所述至少一个电极的第一部分， 领先身体的第一位; 至少部分地由与所述绝缘构件不同的材料形成并且与所述绝缘构件连接的加强构件，所述加强构件在所述绝缘构件和所述绝缘构件与所述绝缘构件之间的所述引线本体的外表面上轴向延伸。 加强构件可以构造成将径向或轴向力中的至少一个从加强构件的近侧部分传递到绝缘构件，其中传递到绝缘构件的径向或轴向力中的至少一个足以使 绝缘构件在引线体的外表面上。 在一些示例中，引线还可包括可展开的隆起部件，其构造成将加强部件和绝缘部件固定在患者体内的组织部位附近。

公开(公告)号：US20120232606A1

公开(公告)日：2012-09-13

申请号：US13357659

申请日：2012-01-25

申请人： Yong-Fu Xiao ,  Jeffrey M. Gillberg ,  Paul J. DeGroot ,  Eduardo N. Warman ,  Scott J. Brabec ,  John L. Sommer ,  Jon F. Urban ,  Lepeng Zeng

发明人： Yong-Fu Xiao ,  Jeffrey M. Gillberg ,  Paul J. DeGroot ,  Eduardo N. Warman ,  Scott J. Brabec ,  John L. Sommer ,  Jon F. Urban ,  Lepeng Zeng

IPC分类号： A61N1/365

CPC分类号： A61N1/365 ,  A61N1/3622 ,  A61N1/36585

摘要： An apparatus and method to discriminate cardiac events by sensing atrial and ventricular depolarizations having associated refractory periods thereafter. A fast ventricular rate is detected in response to the sensed ventricular depolarizations. Responsive to detecting the fast ventricular rate, at least one stimulus pulse is delivered to atrial tissue within the associated refractory period of the ventricle but outside of an associated refractory period of the stimulated atrial tissue. A ventricular response to the atrial tissue stimulus pulse is determined, and the cardiac event is discriminated based on the ventricular response to the atrial tissue stimulus pulse.

公开(公告)号：US07860580B2

公开(公告)日：2010-12-28

申请号：US11379849

申请日：2006-04-24

申请人： Jeffrey G. Falk ,  Douglas N. Hess ,  John L. Sommer

发明人： Jeffrey G. Falk ,  Douglas N. Hess ,  John L. Sommer

IPC分类号： A61N1/362

CPC分类号： A61N1/0573 ,  A61N2001/0585

摘要： A medical electrical lead includes a proximal insulation segment, a distal insulation segment, a conductor extending within the proximal and distal segments, and an electrode coupled to the conductor and disposed in proximity to a distal end of the distal insulation segment. A fixation element of the lead is coupled to a distal end of the proximal insulation segment and includes a wire wound in a helix, which extends distally from the proximal segment, over the distal insulation segment.

摘要翻译： 医疗电引线包括近端绝缘段，远侧绝缘段，在近端段和远侧区段内延伸的导体，以及耦合到导体并设置在远端绝缘区段的远端附近的电极。 引线的固定元件联接到近端绝缘节段的远端，并且包括缠绕在远端绝缘节段上的从近端段向远端延伸的螺旋线的线。