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204 条记录 (耗时 0.034 秒)

    Method and apparatus for using heart rate variability as a safety check in electrical therapies
    61.
    发明申请
    Method and apparatus for using heart rate variability as a safety check in electrical therapies 失效
    使用心率变异性作为电疗法安全检查的方法和装置

    公开(公告)号：US20060161209A1

    公开(公告)日：2006-07-20

    申请号：US11037309

    申请日：2005-01-18

    申请人： Joseph Pastore ,  Rodney Salo ,  Gerrard Carlson ,  Andrew Kramer ,  Jiang Ding ,  Yinghong Yu

    发明人： Joseph Pastore ,  Rodney Salo ,  Gerrard Carlson ,  Andrew Kramer ,  Jiang Ding ,  Yinghong Yu

    IPC分类号： A61N1/362

    CPC分类号： A61N1/365 ,  A61N1/36592

    摘要： A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used as a safety check to stop an electrical therapy when it is believed to be potentially harmful to continue the therapy.

    摘要翻译： 心律管理系统基于心率变异性（HRV）调节起搏和/或自主神经刺激脉冲的传递。 产生作为HRV的量度的HRV参数以指示患者的心脏状况，基于该HRV参数开始，停止，调整或优化起搏和/或自主神经刺激脉冲的递送。 在一个实施例中，当HRV参数被认为对继续治疗有潜在危害时，将HRV参数用作安全检查以停止电疗法。

    Detection and treatment of prolonged inter-atrial delay in cardiac resynchronization patients
    62.
    发明申请
    Detection and treatment of prolonged inter-atrial delay in cardiac resynchronization patients 审中-公开
    心脏再同步化患者延长心房延迟的检测与治疗

    公开(公告)号：US20060041279A1

    公开(公告)日：2006-02-23

    申请号：US11113809

    申请日：2005-04-25

    申请人： Yinghong Yu ,  Jiang Ding ,  Milton Morris

    发明人： Yinghong Yu ,  Jiang Ding ,  Milton Morris

    IPC分类号： A61N1/362

    CPC分类号： A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

    摘要： A method and system for identifying and assessing inter-atrial conduction delays in patients is disclosed. Patients who are so identified and are also in need of ventricular resynchronization therapy may then be treated with left atrial pacing and ventricular resynchronization pacing. Certain patients may alternatively be treated with ventricular resynchronization therapy delivered with a conservatively selected atrio-ventricular delay interval and without left atrial pacing.

    摘要翻译： 公开了一种用于识别和评估患者心房间传导延迟的方法和系统。 那些如此确定并且也需要心室再同步治疗的患者然后可以用左心房起搏和心室再同步起搏治疗。 某些患者可以替代地以具有保守选择的心房延迟间隔并且没有左心房起搏的心室再同步治疗进行治疗。

    Apparatus and method for determining responders to cardiac resynchronization therapy using implantable accelerometers
    64.
    发明授权
    Apparatus and method for determining responders to cardiac resynchronization therapy using implantable accelerometers 有权
    用于使用可植入加速度计确定心脏再同步治疗的响应者的装置和方法

    公开(公告)号：US06923772B2

    公开(公告)日：2005-08-02

    申请号：US10236714

    申请日：2002-09-06

    申请人： Yinghong Yu ,  Jiang Ding ,  Qingsheng Zhu

    发明人： Yinghong Yu ,  Jiang Ding ,  Qingsheng Zhu

    IPC分类号： A61B5/11 ,  A61B5/02

    CPC分类号： A61B5/1107 ,  A61B5/6869 ,  A61B5/7242 ,  A61B2562/0219

    摘要： A device for measuring a synchronicity of contraction of a heart to determine if an individual would be a responder to cardiac resynchronization therapy. The device may include a first electrode positioned at a first ventricular wall location to measure movement of the first ventricular wall location and generate a first signal, as well as a second electrode positioned at a second ventricular wall location to measure movement of the second ventricular wall location and generate a second signal. A processing module may process the first and second signals, for example, integrate the signals multiple times, and generate an output based on the processed signals. Based on this output, an individual can be labeled a responder or non-responder to cardiac resynchronization therapy. The electrodes may each include an accelerometer to measure acceleration of the heart wall.

    摘要翻译： 用于测量心脏收缩的同步性的装置，以确定个体是否是心脏再同步治疗的应答​​者。 该装置可以包括位于第一心室壁位置处的第一电极，以测量第一心室壁位置的运动并产生第一信号，以及定位在第二心室壁位置处的第二电极，以测量第二心室壁的运动 位置并产生第二个信号。 处理模块可以处理第一和第二信号，例如，多次对信号进行积分，并且基于处理的信号生成输出。 基于该输出，个体可以被标记为心脏再同步治疗的应答​​者或非应答者。 电极可以各自包括用于测量心脏壁的加速度的加速度计。

    Cardiac resynchronization system employing mechanical measurement of cardiac walls
    67.
    发明授权
    Cardiac resynchronization system employing mechanical measurement of cardiac walls 有权
    心脏再同步系统采用心脏壁的机械测量

    公开(公告)号：US08792980B2

    公开(公告)日：2014-07-29

    申请号：US12980417

    申请日：2010-12-29

    申请人： Yinghong Yu ,  Jiang Ding ,  Qingsheng Zhu

    发明人： Yinghong Yu ,  Jiang Ding ,  Qingsheng Zhu

    IPC分类号： A61N1/368 ,  A61N1/365

    CPC分类号： A61N1/36578 ,  A61N1/3627 ,  A61N1/36542 ,  A61N1/3684

    摘要： Methods and devices are disclosed for employing mechanical measurements to synchronize contractions of ventricular wall locations. Accelerometers that may be placed within electrode leads are positioned at ventricular wall locations, such as the left ventricle free wall, right ventricle free wall, and the anterior wall/septum wall. The accelerometers produce signals in response to the motion of the ventricular wall locations. A processor may then compare the signals to determine a difference in the synchronization of the ventricular wall location contractions. The difference in synchronization can be determined in various ways such as computing a phase difference and/or amplitude difference between the accelerometer signals. One or more stimulation pulses may be provided per cardiac cycle to resynchronize the contractions as measured by the accelerometers to thereby constantly and automatically optimize the cardiac resynchronization therapy.

    摘要翻译： 公开了用于采用机械测量来同步心室壁位置收缩的方法和装置。 可以放置在电极引线内的加速度计定位在心室壁位置，例如左心室游离壁，右心室游离壁和前壁/隔膜壁。 加速度计响应于心室壁位置的运动产生信号。 然后，处理器可以比较信号以确定心室壁位置收缩的同步的差异。 可以以各种方式确定同步差异，例如计算加速度计信号之间的相位差和/或振幅差。 可以在每个心动周期提供一个或多个刺激脉冲，以重新同步由加速度计测量的收缩，从而不断地和自动地优化心脏再同步治疗。

    Cardiac resynchronization therapy optimization using cardiac activation sequence information
    68.
    发明授权
    Cardiac resynchronization therapy optimization using cardiac activation sequence information 有权
    心脏再同步治疗优化使用心脏激活序列信息

    公开(公告)号：US08725255B2

    公开(公告)日：2014-05-13

    申请号：US11601216

    申请日：2006-11-17

    申请人： Shantha Arcot-Krishnamurthy ,  Yi Zhang ,  Jiang Ding ,  Yinghong Yu ,  Yanting Dong

    发明人： Shantha Arcot-Krishnamurthy ,  Yi Zhang ,  Jiang Ding ,  Yinghong Yu ,  Yanting Dong

    IPC分类号： A61N1/365 ,  A61N1/362

    CPC分类号： A61N1/3627 ,  A61B5/04011 ,  A61B5/0452 ,  A61N1/365 ,  A61N1/36535 ,  A61N1/36542

    摘要： Systems and methods provide for pacing a heart to improve pumping efficiency of the heart, such as by producing a cardiac fusion response for patient's subject to cardiac resynchronization therapy. A pacing parameter, such as an A-V delay, V-V delay, lead/electrode configuration or vector, is adjusted and a cardiac signal vector representative of all or a portion of one or more cardiac activation sequences is monitored during pacing parameter adjustment. A change in a characteristic of the cardiac signal vector is detected in response to an adjusted pacing parameter, the change indicative of a cardiac fusion response. A pacing therapy may be delivered to produce the cardiac fusion response using the adjusted pacing parameter.

    摘要翻译： 系统和方法提供心脏起搏以改善心脏的泵送效率，例如通过为患者进行心脏再同步治疗产生心脏融合反应。 调整起搏参数，例如A-V延迟，V-V延迟，引线/电极配置或载体，并且在起搏参数调整期间监测表示一个或多个心脏激活序列的全部或一部分的心脏信号载体。 响应于调整的起搏参数，指示心脏融合反应的变化来检测心脏信号载体的特性变化。 可以使用调整的起搏参数来递送起搏治疗以产生心脏融合反应。

    ECTOPIC-TRIGGERED PARA-HIS STIMULATION
    70.
    发明申请
    ECTOPIC-TRIGGERED PARA-HIS STIMULATION 审中-公开

    公开(公告)号：US20130158621A1

    公开(公告)日：2013-06-20

    申请号：US13716810

    申请日：2012-12-17

    申请人： Jiang Ding ,  Allan C. Shuros ,  Dan Li ,  Yinghong Yu ,  Stephen J. Hahn

    发明人： Jiang Ding ,  Allan C. Shuros ,  Dan Li ,  Yinghong Yu ,  Stephen J. Hahn

    IPC分类号： A61N1/365

    CPC分类号： A61N1/36592 ,  A61B5/02152 ,  A61B5/0464 ,  A61B5/0468 ,  A61N1/365 ,  A61N1/37 ,  A61N1/371

    摘要： Ectopic cardiac activity can be detected, such as in the absence of a diagnosed tachyarrhythmia episode. In response to the detected ectopic activity, electrostimulation can be provided to a para-Hisian region, such as to activate natural cardiac contraction mechanisms or to interrupt re-entrant cardiac activity. Subsequent ectopic cardiac activity can be detected, and subsequent electrostimulation can be provided to the para-Hisian region, such as according to one or more adjustable electrostimulation parameters.

    摘要翻译： 可以检测异位心脏活动，例如在没有诊断的快速性心律失常发作时。 响应于检测到的异位活动，可以向对等神经区域提供电刺激，例如激活自然心脏收缩机制或中断再入心脏活动。 可以检测随后的异位心脏活动，并且可以根据一个或多个可调节的电刺激参数来向对 - Hisian区域提供随后的电刺激。