公开(公告)号：US20080153707A1

公开(公告)日：2008-06-26

申请号：US11883957

申请日：2006-02-15

申请人： Markus Gewehr ,  Jochen Dietz ,  Thomas Grote ,  Carsten Blettner ,  Wassilios Grammenos ,  Udo Hunger ,  Bernd Muller ,  Frank Schieweck ,  Anja Schwogler ,  Jan Klaas Lohmann ,  Joachim Rheinheimer ,  Peter Schafer ,  Siegfried Strathmann ,  Reinhard Stierl

发明人： Markus Gewehr ,  Jochen Dietz ,  Thomas Grote ,  Carsten Blettner ,  Wassilios Grammenos ,  Udo Hunger ,  Bernd Muller ,  Frank Schieweck ,  Anja Schwogler ,  Jan Klaas Lohmann ,  Joachim Rheinheimer ,  Peter Schafer ,  Siegfried Strathmann ,  Reinhard Stierl

IPC分类号： A01N43/56 ,  C07D231/00 ,  A01N25/26

CPC分类号： C07D231/14 ,  A01N43/56

摘要： The present invention relates to pyrazolecarboxanilides I in which the variables are as defined below: n is zero or 2; m is 2 or 3; X1 is fluorine or chlorine; X2 is halogen; Y is CN, NO2, C1-C4-alkyl, C1-C4-haloalkyl, methoxy or methylthio; p is zero or 1; R1 is fluorine, chlorine, bromine, C1-C4-alkyl or C1-C4-haloalkyl; R2 is hydrogen or halogen; R3 is hydrogen, methyl or ethyl; W is O or S; with the proviso that, if a) W═O, R1=methyl and R3 is hydrogen, R2 is not fluorine, or b) W═O, n=0, m=2, p=0, R2 and R3 are hydrogen, R1 is not trifluoromethyl or difluoromethyl, to processes for preparing these compounds, to compositions comprising them and to methods for using them for controlling harmful fungi.

摘要翻译： 本发明涉及吡唑烷酰苯胺I，其中变量如下：n为0或2; m为2或3; X 1是氟或氯; X 2是卤素; Y是CN，NO 2，C 1 -C 4 - 烷基，C 1 -C 3 - 4 - 卤代烷基，甲氧基或甲硫基; p为零或1; R 1是氟，氯，溴，C 1 -C 4 - C 1-4烷基或C 1 -C 3 - 低级烷基; R 2是氢或卤素; R 3是氢，甲基或乙基; W为O或S; 条件是，如果a）WO，R 1 =甲基和R 3是氢，R 2不是氟，或b） WO，n = 0，m = 2，p = 0，R 2和R 3是氢，R 1不是三氟甲基或二氟甲基 ，制备这些化合物的方法，包含它们的组合物以及用于控制有害真菌的方法。

公开(公告)号：US20050107401A1

公开(公告)日：2005-05-19

申请号：US10505146

申请日：2003-02-06

申请人： Frank Schieweck ,  Jordi Blasco ,  Thomas Grote ,  Andreas Gypser ,  Bernd Muller ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schafer ,  Wassilios Grammenos ,  Markus Gewehr ,  Anja Schwogler ,  Carsten Blettner ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Frank Schieweck ,  Jordi Blasco ,  Thomas Grote ,  Andreas Gypser ,  Bernd Muller ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schafer ,  Wassilios Grammenos ,  Markus Gewehr ,  Anja Schwogler ,  Carsten Blettner ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： A01N43/54 ,  C07D401/04 ,  A61K31/506 ,  C07D43/04

CPC分类号： C07D401/04

摘要： The invention relates to 2-(2-pyridyl)-5-phenyl-6-amninopyrimidines of formula I, wherein the substitutes and the index have the following meaning: R1 represents halogen, hydroxy, hyano, hxo, nitro, amino, mercapto, alkyl, halogenalkyl, alkenyl, alkinyl, cycloalkyl, alkoxy, halogenalkoxy, carboxyl, alkoxycarbonyl, carbamoyl, alkylaminocarbonyl, dialkylamincarbonyl, morpholinocarbonyl, pyrrolidinocarbonyl, alkylcarbonylamino, alkylamino. dialkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, hydroxysulfonyl, aminosulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl; m=0 or 1-4; R2 represents hydrogen, halogen, cyano, alkyl, halogenalkyl or alkoxy; R3, R4 represents hydrogen, alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl, R3 and R4 together with the nitrogen atom to which they are connected, form a five or six-membered ring which is interrupted by an atom from the group O, N or S and/or can be substituted according to the description; R5 represents halogen, alkyl or halogenalkyl; R6 represents hydrogen or one of the known groups in R5; R7, R8 represent hydrogen, halogen, alkyl or halogenalkyl; R9 represents hydrogen, halogen, hydroxy, cyano, alkyl, alkoxy, cycloalkoxy, halogenalkoxy, alkoxycarbonyl or alkylaminocarbonyl. The invention also relates to a method and intermediate product for the production of said compound in addition to the use thereof for combating undesirable plants.

摘要翻译： 本发明涉及式I的2-（2-吡啶基）-5-苯基-6-脒嘧啶，其中取代基和指数具有以下含义：R 1表示卤素，羟基，杂环基， 烷氧基，烷氧基羰基，氨基甲酰基，烷基氨基羰基，二烷基氨基羰基，吗啉代羰基，吡咯烷基羰基，烷基羰基氨基，烷基氨基。 二烷基氨基，烷硫基，烷基亚磺酰基，烷基磺酰基，羟基磺酰基，氨基磺酰基，烷基氨基磺酰基，二烷基氨基磺酰基; m = 0或1-4; R 2表示氢，卤素，氰基，烷基，卤代烷基或烷氧基; R 3，R 4表示氢，烷基，卤代烷基，环烷基，卤代烷基，烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，R 3 O 和R 4与它们连接的氮原子一起形成5或6元环，其被来自基团O，N或S的原子和/或可被取代 根据说明; R 5表示卤素，烷基或卤代烷基; R 6表示氢或R 5中的已知基团之一; R 7，R 8表示氢，卤素，烷基或卤代烷基; R 9表示氢，卤素，羟基，氰基，烷基，烷氧基，环烷氧基，卤代烷氧基，烷氧基羰基或烷基氨基羰基。 本发明还涉及用于生产所述化合物的方法和中间产物，除了其用于对抗不期望的植物之外。

公开(公告)号：US20050272749A1

公开(公告)日：2005-12-08

申请号：US10531981

申请日：2003-11-04

申请人： Jordi Tormo Blasco ,  Carsten Bletner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Jordi Tormo Blasco ,  Carsten Bletner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： C07D487/04 ,  A61K31/519

CPC分类号： C07D487/04

摘要： 5-Alkyl-7-aminotriazolopyrimidines of the formula I, where: R1, R2 are hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl, phenyl, naphthyl; 5- or 6-membered saturated, unsaturated or aromatic heterocyclyl which contains one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom; or R1 and R2 together with the bridging nitrogen atom can form a 5- or 6-membered ring which contains one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom; R3 is cycloalkyl or bicycloalkyl; where R1, R2 and R3 may be substituted as outlined in the description; X is alkyl or haloalkyl; and their salts; processes and intermediates for their preparation, compositions comprising them and their use for controlling phytopathogenic harmful fungi are described.

摘要翻译： 式I的5-烷基-7-氨基三唑并嘧啶，其中：R 1，R 2是氢，烷基，烯基，炔基，卤代烷基，环烷基，苯基，萘基; 含有1-4个氮原子或一至三个氮原子和一个硫或氧原子的5-或6-元饱和，不饱和或芳族杂环基; 或R 1和R 2与桥连氮原子一起可以形成含有1-4个氮原子或一至三个氮原子的5-或6-元环，并且 一个硫或氧原子; R 3是环烷基或双环烷基; 其中R 1，R 2和R 3可以如说明书中概述的那样被取代; X是烷基或卤代烷基; 和它们的盐; 描述了其制备方法和中间体，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US07550471B2

公开(公告)日：2009-06-23

申请号：US10531981

申请日：2003-11-04

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  A61K31/519 ,  C07D487/00

CPC分类号： C07D487/04

摘要： The invention relates to 5-alkyl-7-aminotriazolopyrimidines of the formula (I) and to the salts thereof. In said formula substituents have the following meanings: R1 and R2 each is a hydrogen atom or a group of alkyl, alcenyl, haloalkyl, cycloalky, phenyl or naphtyle, saturated, unstaturated or aromatic heterocycle having from five to six members which contain from one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, or R1 and R2 can from together with a connecting them nitrogen atom a cycle of 5 to 6 members containing from one to four nitrogen atoms or from one to three nitrogen atoms and one sulfur or oxygen atom, R3 is a cycloalkyl or bicycloalkyl group, R1, R2 and R3 can be substituted in conformity with a description, and X is an alkyl or alkyl halide group. The inventive methods and intermediary products necessary for producing said compounds, agents containing them and the use therefore for fighting against harmful mushroom are also disclosed.

摘要翻译： 本发明涉及式（I）的5-烷基-7-氨基三唑并嘧啶及其盐。 在所述式中，取代基具有以下含义：R 1和R 2各自为氢原子或具有5至6个成员的烷基，烯基，卤代烷基，环烷基，苯基或萘杂，饱和的，不饱和的或芳族杂环的基团， 四个氮原子或一个至三个氮原子和一个硫或氧原子，或者R 1和R 2可以连同它们的氮原子一起包含5至6个含有1-4个氮原子或1-3个氮原子的成员 和一个硫或氧原子，R 3为环烷基或双环烷基，R 1，R 2和R 3可以根据说明书进行取代，X为烷基或卤代烷基。 还公开了生产所述化合物所需的创造性方法和中间产物，含有它们的试剂和用于防止有害蘑菇的用途。

公开(公告)号：US07501530B2

公开(公告)日：2009-03-10

申请号：US10548840

申请日：2004-03-20

申请人： Markus Gewehr ,  Bernd Müller ,  Thomas Grote ,  Wassilios Grammenos ,  Andreas Gypser ,  Jordi Tormo i Blasco ,  Anja Schwögler ,  Joachim Rheinheimer ,  Carsten Blettner ,  Frank Schieweck ,  Michael Rack ,  Ulrich Schöfl ,  Siegfried Strathmann ,  Reinhard Stierl ,  Jan Rether

发明人： Markus Gewehr ,  Bernd Müller ,  Thomas Grote ,  Wassilios Grammenos ,  Andreas Gypser ,  Jordi Tormo i Blasco ,  Anja Schwögler ,  Joachim Rheinheimer ,  Carsten Blettner ,  Frank Schieweck ,  Michael Rack ,  Ulrich Schöfl ,  Siegfried Strathmann ,  Reinhard Stierl ,  Jan Rether

IPC分类号： C07D333/22 ,  C07C333/32 ,  A01N25/00 ,  C07C335/00 ,  A01N25/32

CPC分类号： C07D333/38

摘要： The invention relates to novel biphenyl carboxamides of formula (I), wherein A, R, Z, X, Y, m and n have the meanings given in the description, to multiple methods for producing these substances, to their use for combating unwanted micro-organisms and to novel intermediate products and the production thereof.

摘要翻译： 本发明涉及式（I）的新型联苯甲酰胺，其中A，R，Z，X，Y，m和n具有与本说明书中给出的含义相同的多种生产这些物质的方法，用于防治不想要的微生物 和新颖的中间产品及其生产。

公开(公告)号：US07094894B2

公开(公告)日：2006-08-22

申请号：US10513030

申请日：2003-04-30

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D487/04 ,  A01N43/90 ,  C07C69/618

CPC分类号： C07D487/04 ,  A01N43/90 ,  C07C69/65

摘要： Disclosed are a method for producing fungicidal triazolopyrimidine compounds, agents containing said compounds, and the use thereof for controlling harmful fungi. Also disclosed are triazolopyrimidines of formula (I), in which the substituents have the following meaning: L1 represents alkyl; L2 represents halogen; L3represents hydrogen or halogen; X represents halogen, cyano, alkyl, alkoxy, or haloalkoxy; R1, R2 represent hydrogen, alkyl, haloalkyl, cycloalkyl, alkenyl, alkadienyl, alkinyl, or cycloalkinyl, phenyl, naphthyl, or a five-unit to ten-unit saturated, partially unsaturated, or aromatic heterocycle containing one to four heteroatoms from the group O, N, or S, R1 and R2 can also form a five-unit or six-unit ring along with the nitrogen atom to which they are linked. Said ring can be interrupted and/or substituted by an atom from the group O, N, and S while R1 and/or R2 can be substituted according to the description. The invention also relates to methods and intermediate products for producing said compounds, agents containing said compounds, and the use thereof for controlling harmful fungi

摘要翻译： 公开了生产杀真菌三唑并嘧啶化合物的方法，含有所述化合物的试剂及其用于控制​​有害真菌的用途。 还公开了式（I）的三唑并嘧啶，其中取代基具有以下含义：L 1表示烷基; L 2表示卤素; L 3表示氢或卤素; X表示卤素，氰基，烷基，烷氧基或卤代烷氧基; R 1，R 2代表氢，烷基，卤代烷基，环烷基，烯基，链二烯基，炔基或环炔基，苯基，萘基或五个单元至十个单元 饱和的，部分不饱和的或含有一至四个O，N或S杂原子的杂环，R 1和R 2也可以形成五单元或 六单元环与它们所连接的氮原子一起。 所述环可以被O，N和S基团的原子中断和/或取代，而R 1和/或R 2可以根据描述被取代 。 本发明还涉及用于生产所述化合物的方法和中间产物，含有所述化合物的试剂及其用于控制​​有害真菌的用途

公开(公告)号：US07763622B2

公开(公告)日：2010-07-27

申请号：US10532719

申请日：2003-11-04

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  A61K31/519 ,  C07D471/00 ,  C07D487/00 ,  C07D491/00

CPC分类号： C07C69/65 ,  A01N43/90 ,  C07D487/04

摘要： Substituted 6-(2-halogenphenyl)-triazolopyrimidines of formula I in which R1 denote alkyl, alkenyl, alkynyl, alkadienyl, haloalkyl, haloalkenyl, cycloalkyl, phenyl, naphthyl, or a 5- or 6-membered saturated, unsaturated, or aromatic heterocycle, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, wherein R1 and R2 radicals may be substituted as defined in the description, R2 denote hydrogen, or a group mentioned for R1; or R1 and R2 together with the interjacent nitrogen atom represent a 5- or 6-membered heterocycle, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, which ring may be substituted as defined in the description; Hal is halogen; L1, L3 independently denote hydrogen, halogen, or alkyl; L2 is hydrogen, halogen, haloalkyl, or NH2, NHRb, or N(Rb)2, wherein Rb is as defined in the description, wherein at least one from L1, L2, and L3 is not hydrogen; X is halogen, cyano, alkyl, alkoxy, haloalkoxy or alkenyloxy. processes for their preparation, compositions containing them and to their use for combating phytopathogenic fungi.

摘要翻译： 取代的式I的6-（2-卤代苯基） - 三唑并嘧啶，其中R 1表示烷基，烯基，炔基，链二烯基，卤代烷基，卤代烯基，环烷基，苯基，萘基或5-或6-元饱和，不饱和或芳族杂环 含有一至四个氮原子或一至三个氮原子和一个硫或氧原子，其中R 1和R 2基团可以如说明书中所定义而被取代，R 2表示氢或R 1所提及的基团; 或R1和R2与相邻的氮原子一起表示含有1-4个氮原子或一至三个氮原子和一个硫或氧原子的5-或6-元杂环，该环可以如说明书中所定义而被取代; 卤素是卤素; L 1，L 3独立地表示氢，卤素或烷基; L2是氢，卤素，卤代烷基或NH2，NHRb或N（Rb）2，其中Rb如说明书中所定义，其中L1，L2和L3中的至少一个不是氢; X是卤素，氰基，烷基，烷氧基，卤代烷氧基或烯氧基。 其制备方法，含有它们的组合物及其用于对抗植物病原真菌的用途。

公开(公告)号：US07320975B2

公开(公告)日：2008-01-22

申请号：US10505146

申请日：2003-02-06

申请人： Frank Schieweck ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Andreas Gypser ,  Bernd Müller ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Wassilios Grammenos ,  Markus Gewehr ,  Anja Schwögler ,  Carsten Blettner ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Frank Schieweck ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Andreas Gypser ,  Bernd Müller ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Wassilios Grammenos ,  Markus Gewehr ,  Anja Schwögler ,  Carsten Blettner ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D401/04 ,  A01N43/54

CPC分类号： C07D401/04

摘要： The invention relates to 2-(2-pyridyl)-5-phenyl-6-aminopyrimidines of formula I, wherein the substitutes and the index have the following meaning: R1 represents halogen, hydroxy, hyano, hxo, nitro, amino, mercapto, alkyl, halogenalkyl, alkenyl, alkinyl, cycloalkyl, alkoxy, halogenalkoxy, carboxyl, alkoxycarbonyl, carbamoyl, alkylaminocarbonyl, dialkylamincarbonyl, morpholinocarbonyl, pyrrolidinocarbonyl, alkylcarbonylamino, alkylamino. dialkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, hydroxysulfonyl, aminosulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl; m=0 or 1-4; R2 represents hydrogen, halogen, cyano, alkyl, halogenalkyl or alkoxy; R3, R4 represents hydrogen, alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl, R3 and R4 together with the nitrogen atom to which they are connected, form a five or six-membered ring which is interrupted by an atom from the group O, N or S and/or can be substituted according to the description; R5 represents halogen, alkyl or halogenalkyl; R6 represents hydrogen or one of the known groups in R5; R7, R8 represent hydrogen, halogen, alkyl or halogenalkyl; R9 represents hydrogen, halogen, hydroxy, cyano, alkyl, alkoxy, cycloalkoxy, halogenalkoxy, alkoxycarbonyl or alkylaminocarbonyl. The invention also relates to a method and intermediate product for the production of said compound in addition to the use thereof for combating undesirable plants

摘要翻译： 本发明涉及式I的2-（2-吡啶基）-5-苯基-6-氨基嘧啶，其中取代基和指数具有以下含义：R 1表示卤素，羟基，杂环基， 烷氧基，烷氧基羰基，氨基甲酰基，烷基氨基羰基，二烷基氨基羰基，吗啉代羰基，吡咯烷基羰基，烷基羰基氨基，烷基氨基。 二烷基氨基，烷硫基，烷基亚磺酰基，烷基磺酰基，羟基磺酰基，氨基磺酰基，烷基氨基磺酰基，二烷基氨基磺酰基; m = 0或1-4; R 2表示氢，卤素，氰基，烷基，卤代烷基或烷氧基; R 3，R 4表示氢，烷基，卤代烷基，环烷基，卤代烷基，烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，R 3 O 和R 4与它们连接的氮原子一起形成5或6元环，其被来自基团O，N或S的原子和/或可被取代 根据说明; R 5表示卤素，烷基或卤代烷基; R 6表示氢或R 5中的已知基团之一; R 7，R 8表示氢，卤素，烷基或卤代烷基; R 9表示氢，卤素，羟基，氰基，烷基，烷氧基，环烷氧基，卤代烷氧基，烷氧基羰基或烷基氨基羰基。 本发明还涉及用于生产所述化合物的方法和中间产物，除了其用于对抗不期望的植物之外

公开(公告)号：US07148227B2

公开(公告)日：2006-12-12

申请号：US10508409

申请日：2003-03-19

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl ,  Ulrich Schöfl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl ,  Ulrich Schöfl

IPC分类号： A61K31/519 ,  C07D487/04 ,  C07C69/738

CPC分类号： C07D487/04 ,  A01N43/90 ,  C07C255/57

摘要： The invention relates to triazolopyrimidines of formula (I), in which the substituents are defined as follows: L1 represents cyano, S(═O)nA1 or C(═O)A2, wherein A1 stands for hydrogen, hydroxy, alkyl, alkylamino or dialkylamino; A2 stands for C1–C8 alkoxy, C1–C6 haloalkoxy or one of the groups named in A1; and n stands for 0, 1 or 2; L2, L3 represent hydrogen or halogen; L4, L5 represent hydrogen, halogen or alkyl; X represents halogen, cyano, alkyl, haloalkyl, alkoxy or haloalkoxy; R1 represents alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, alkadienyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl or cycloalkynyl, phenyl, naphthyl, or a five to ten-membered saturated, partially unsaturated or aromatic heterocyclus containing between one and four heteroatoms from the group containing O, N or S; R2 represents hydrogen or R1; R1 and R2 can form, together with the nitrogen atom to which they are bonded, a five or six-membered ring, which can be interrupted and/or substituted by an atom from the group O, N and S; whereby R1 and/or R2 can be substituted in accordance with the description. The invention also relates to methods and intermediate products for producing said compounds, to agents containing the latter and to the use of said compounds for combating harmful fungi.

摘要翻译： 本发明涉及式（I）的三唑并嘧啶，其中取代基定义如下：L 1表示氰基，S（-O）n A 1 或其中A 1代表氢，羟基，烷基，烷基氨基或二烷基氨基;或C（= O） A 2代表C 1 -C 8烷氧基，C 1 -C 6烷基，C 1 -C 6 - >卤代烷氧基或在A 中命名的基团之一; 而n代表0,1或2; L 2，L 3表示氢或卤素; L 4，L 5代表氢，卤素或烷基; X表示卤素，氰基，烷基，卤代烷基，烷氧基或卤代烷氧基; R 1表示烷基，卤代烷基，环烷基，卤代环烷基，烯基，链烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，苯基，萘基或五至十元饱和，部分不饱和或芳族杂环 含有一个至四个来自含有O，N或S的基团的杂原子; R 2表示氢或R 1; R 1和R 2可以与它们所键合的氮原子一起形成五元或六元环，其可被中断和/或被 来自O，N和S族的原子; 其中R 1和/或R 2可以根据描述被取代。 本发明还涉及用于生产所述化合物的方法和中间产物，含有后者的试剂和所述化合物用于防治有害真菌的用途。

公开(公告)号：US20050181948A1

公开(公告)日：2005-08-18

申请号：US10509112

申请日：2003-03-27

申请人： Wassilios Grammenos ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Andreas Gypser ,  Bernd Muller ,  Joachim Rheinheimer ,  Peter Schafer ,  Anja Schwogler ,  Jordi Blasco ,  Norbert Gotz ,  Gisela Lorenz ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Reinhard Stierl

发明人： Wassilios Grammenos ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Andreas Gypser ,  Bernd Muller ,  Joachim Rheinheimer ,  Peter Schafer ,  Anja Schwogler ,  Jordi Blasco ,  Norbert Gotz ,  Gisela Lorenz ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Reinhard Stierl

IPC分类号： C07D213/56 ,  C07D213/61 ,  C07D263/10 ,  A01N43/60 ,  A01N43/40 ,  A01N43/54

CPC分类号： C07D263/10 ,  C07D213/56 ,  C07D213/61

摘要： The present invention relates to novel phenethylacrylamides of the formula I in which the substituents R1, R2, R3 and R4 have the following meanings: R1 is hydrogen, halogen, C1-C4-alkyl, C1-C4-alkoxy, C3-C8-cycloalkyl, C1-C4-haloalkoxy or C1-C4-haloalkyl; R2 is hydrogen, halogen, C1-C4-alkyl, C1-C4-alkoxy, C3-C10-cycloalkyl, C1-C4-haloalkoxy or C1-C4-haloalkyl; R3 is C1-C4-alkyl, C1-C4-haloalkyl, propargyl, C3-C4-alkenyl or a radical of the formula —H2C—C≡C—C(Ra, Ra)—Rc, wherein Ra, Rb independently of one another are hydrogen or methyl and Rc is hydrogen or C1-C4-alkyl; R4 is methyl or C1-haloalkyl; and Het is a 5- or 6-membered heteroaromatic ring, to processes for their preparation, and to the use of phenethylacrylamides of the formula I for controlling phytopathogenic harmful fungi.

摘要翻译： 本发明涉及式I的新的苯乙基丙烯酰胺，其中取代基R 1，R 2，R 3和R 4 具有以下含义：R 1是氢，卤素，C 1 -C 4 - 烷基，C 1 C 1 -C 4 - 烷氧基，C 3 -C 8 - 环烷基，C 1 -C 4 - 卤代烷氧基或C 1 -C 4 - 卤代烷基; R 2是氢，卤素，C 1 -C 4 - 烷基，C 1 -C 3 - 4 - 烷氧基，C 3 -C 10 - 环烷基，C 1 -C 4 - 卤代烷氧基或C 1 -C 4 - 卤代烷基; R 3是C 1 -C 4 - 烷基，C 1 -C 4烷基，C 1 -C 4烷基，C 1 -C 4 - 烷基，炔丙基，C 3 -C 4 - 烯基或式-H 2C≡CC（R 0）的基团 其中R a，R b，R b独立地为C 1 -C 4，其中R a，R b， 另一个是氢或甲基，R c是氢或C 1 -C 4 - 烷基; R 4是甲基或C 1 - 卤代烷基; 并且Het是5或6元杂芳环，用于其制备方法，以及使用式I的苯乙基丙烯酰胺来控制植物病原性有害真菌。