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118 条记录 (耗时 0.034 秒)

    Bicyclic pyrazolone cytokine inhibitors
    62.
    发明申请
    Bicyclic pyrazolone cytokine inhibitors 失效
    双环吡唑啉酮细胞因子抑制剂

    公开(公告)号：US20050113392A1

    公开(公告)日：2005-05-26

    申请号：US10983114

    申请日：2004-11-05

    申请人： Michael Clark ,  Steven Laughlin ,  Adam Golebiowski ,  Todd Brugel ,  Mark Sabat

    发明人： Michael Clark ,  Steven Laughlin ,  Adam Golebiowski ,  Todd Brugel ,  Mark Sabat

    IPC分类号： A61K31/506 ,  C07D487/04

    CPC分类号： C07D487/04

    摘要： The present invention relates to 6,7-dihydro-5H-pyrazolo[1,2a]pyrazol-1-ones which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 6,7-dihydro-5H-pyrazolo[1,2a]pyrazol-1-ones and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.

    摘要翻译： 本发明涉及抑制炎性细胞因子细胞外释放的6,7-二氢-5H-吡唑并[1,2a]吡唑-1-酮，所述细胞因子负责一个或多个人或更高的哺乳动物疾病状态。 本发明还涉及包含所述6,7-二氢-5H-吡唑并[1,2a]吡唑-1-酮的组合物以及用于预防，减轻或以其他方式控制酶的方法，其被认为是负责 这里描述了疾病状态。

    Torsional vibration damper
    63.
    发明授权
    Torsional vibration damper 失效
    扭转振动阻尼器

    公开(公告)号：US5405296A

    公开(公告)日：1995-04-11

    申请号：US174455

    申请日：1993-12-28

    申请人： Zdenek Cerny ,  Michael Clark

    发明人： Zdenek Cerny ,  Michael Clark

    IPC分类号： F16H7/18 ,  F16F15/126 ,  F16F15/14 ,  F16H55/36 ,  F16H7/08

    CPC分类号： F16F15/126 ,  F16F15/1442 ,  F16H55/36 ,  F16H2055/366

    摘要： A vibration damper assembly operatively connecting a driving pulley with an automotive engine output shaft which drives a serpentine belt system with an automatic belt tensioner. The vibration damper assembly serves to dampen torsional, bending, and transitional vibrations transmitted from the output shaft through the poly-V belt and engine frame to the belt tensioner. The vibration damper assembly comprises a mounting element, fixed to the output shaft, in torsional transmitting relation therewith, bearing member operatively disposed between the driving pulley and the mounting element to restrict relative movement therebetween to torsional relative movement, and a resilient member operatively connected between the driving pulley and the mounting element in resilient torsional transmitting relation therebetween.

    摘要翻译： 振动阻尼器组件可操作地将驱动滑轮与汽车发动机输出轴连接，该自动发动机输出轴用自动皮带张紧器驱动蛇形皮带系统。 振动阻尼器组件用于抑制从输出轴通过多V带和发动机框架传递到皮带张紧器的扭转，弯曲和过渡振动。 减震器组件包括固定到输出轴的安装元件，与扭转传动关系，轴承部件可操作地设置在驱动滑轮和安装元件之间，以限制其间的相对运动以扭转相对运动，以及可操作地连接在 驱动滑轮和安装元件之间具有弹性扭转传递关系。

    Golf game
    64.
    发明授权
    Golf game 失效
    高尔夫游戏

    公开(公告)号：US5000460A

    公开(公告)日：1991-03-19

    申请号：US489466

    申请日：1990-03-06

    申请人： Joseph Barbiaux ,  Michael Clark

    发明人： Joseph Barbiaux ,  Michael Clark

    IPC分类号： A63F1/02 ,  A63F1/04 ,  A63F1/18 ,  A63F3/00 ,  A63F3/02 ,  A63F9/00 ,  A63F9/04 ,  A63F9/06 ,  A63F11/00

    CPC分类号： A63F3/0005 ,  A63F1/04 ,  A63F2001/0441 ,  A63F2003/00242 ,  A63F2003/00488 ,  A63F2009/0039 ,  A63F2009/0426 ,  A63F2009/0643 ,  A63F2009/0663 ,  A63F2011/0023

    摘要： A golf game in which a game board is provided having a plurality of fairways simulating a golf course on which to place players decisions relative to club selection and distance and direction of play, the individual fairway distance and directional slots being determined by throw of dice and putts by rolls of specific numbers on several non-directional dice. Sets of cards bearing instructions for penalities are utilized sccording to rolls of certain numbers on numbered die. Other card sets are employed to when a shot lands on greenside traps or trees. Bonus cards are available occasioned by a roll of particular numbered dice and are to be used according to information given on the back of the said cards. A club selector card is provided listing the different clubs giving distances attained by each of the clubs as determined by the roll of combined numbers of a pair of conventional dice. A direction indicator is adapted to be placed on the hole by each player aimed in his desired direction of play and the same is used also to determine where each shot lands after it is hit. Another is provided for making the position where each shot lands. Movable hazards such as water, trees, sand traps, are provided which can be placed on any hole or holes to redesign the hole as shown on the board and as agreed to by the player or players.

    摘要翻译： 一种高尔夫游戏，其中设置有游戏板，其具有模拟高尔夫球场的多个球道，在球道上放置玩家决定相对于球杆选择以及游戏的距离和方向，个体球道距离和定向时隙由掷骰子确定， 在几个非定向骰子上按特定数量的卷推出。 根据编号的模具上的某些数字的卷使用带有惩罚指示的卡的集合。 当一个镜头落在果岭陷阱或树木上时，其他卡片就被使用。 奖金卡可以由一卷特定编号的骰子提供，并且将根据所述卡背面提供的信息使用。 提供了一种俱乐部选择卡，其中列出了通过一对常规骰子的组合数量的滚动确定的每个俱乐部获得的距离的不同俱乐部。 方向指示器适于由每个玩家按照其期望的游戏方向放置在孔上，并且还使用方向指示器来确定每个射击器在被击中之后落地。 另一个用于制造每个镜头着陆的位置。 提供可移动的危害，例如水，树木，沙漏，可以放置在任何孔或孔上，以重新设计板上所示的洞穴，并由玩家或玩家同意。

    Vibration absorbing mountings
    65.
    发明授权
    Vibration absorbing mountings 失效
    振动吸收装置

    公开(公告)号：US4682753A

    公开(公告)日：1987-07-28

    申请号：US665945

    申请日：1984-10-29

    申请人： Michael Clark

    发明人： Michael Clark

    IPC分类号： F16F13/20 ,  F16F13/00

    CPC分类号： F16F13/20

    摘要： A vibration absorbing mounting for a vehicle engine incorporates hydraulic damping by means of a pair of liquid filled chambers (20,21) which are separated by a thick rubber intermediate diaphragm and communicate via a restricted passageway (32). A gas spring acts on one chamber and a piston (67) sealed by a reinforced rolling-lobe diaphragm (55) acts on the other chamber, the reinforcement of the rolling-lobe diaphragm providing low rolling resistance while maintaining high bulge stiffness.

    摘要翻译： 用于车辆发动机的振动吸收装置通过一对液体填充的腔室（20,21）来结合液压阻尼，所述腔室被厚橡胶中间隔膜隔开并通过限制通道（32）连通。 气体弹簧作用在一个腔室上，并且由加强的滚动瓣膜（55）密封的活塞（67）作用在另一个腔室上，滚动瓣膜的加强件提供低的滚动阻力，同时保持高的凸起刚度。

    Vibration absorbing mountings
    66.
    发明授权
    Vibration absorbing mountings 失效
    振动吸收装置

    公开(公告)号：US4641817A

    公开(公告)日：1987-02-10

    申请号：US590953

    申请日：1984-03-19

    申请人： Michael Clark ,  Kenneth J. Taylor

    发明人： Michael Clark ,  Kenneth J. Taylor

    IPC分类号： F16F13/08 ,  F16F13/10 ,  F16M5/00

    CPC分类号： F16F13/103 ,  F16F13/08 ,  F16F13/105 ,  F16F2230/007

    摘要： A vibration absorbing mounting, e.g. a motor car engine mounting, has a rubber spring member mounted between end members and hydraulically damped. The interior of the mounting comprises two liquid-filled chambers communicating with one another through a restricted passageway and which are separated by an intermediate diaphragm and bounded at their other sides, respectively, by the rubber spring member and a second diaphragm. The second diaphragm is provided with a central support and the intermediate diaphragm may have an unyielding central portion, to enable excessive movement of the end members towards one another to be resisted.

    摘要翻译： 振动吸收装置，例如 摩托车发动机安装，具有安装在端部构件之间的橡胶弹簧构件和液压阻尼。 安装件的内部包括两个通过限制通道彼此连通的液体填充室，它们由中间隔膜隔开，并且分别通过橡胶弹簧构件和第二隔膜分别限定在其另一侧。 第二隔膜设置有中央支撑件，并且中间隔膜可以具有不屈曲的中心部分，以使得端部构件能够彼此过度地移动以被抵抗。

    GENERATOR COUPLING KIT AND METHODS THEREOF
    68.
    发明申请
    GENERATOR COUPLING KIT AND METHODS THEREOF 审中-公开
    发电机联轴器套件及其方法

    公开(公告)号：US20160248229A1

    公开(公告)日：2016-08-25

    申请号：US15144810

    申请日：2016-05-02

    申请人： Michael Clark

    发明人： Michael Clark

    IPC分类号： H02B1/00 ,  G08B21/18 ,  H01H9/28 ,  H02J9/00

    CPC分类号： H02B1/00 ,  G08B21/18 ,  H01H9/281 ,  H01H33/002 ,  H01H71/1054 ,  H02G3/00 ,  H02J9/00 ,  Y10T307/74

    摘要： A generator coupling kit is provided. In exemplary embodiments, the generator coupling kit may comprise a wire adapted to couple with a generator on a first end, the wire adapted to couple with an indoor electrical panel via a generator breaker; and the generator breaker adapted to couple with indoor electrical panel, the generator breaker comprising a circuit breaker.

    摘要翻译： 提供发电机耦合套件。 在示例性实施例中，发电机耦合套件可以包括适于在第一端上与发电机耦合的导线，该线适于经由发电机断路器与室内电气面板耦合; 并且所述发电机断路器适于与室内电气面板耦合，所述发电机断路器包括断路器。

    Address translation with multiple translation look aside buffers
    70.
    发明授权
    Address translation with multiple translation look aside buffers 有权
    地址转换与多个翻译旁边的缓冲区

    公开(公告)号：US08145876B2

    公开(公告)日：2012-03-27

    申请号：US11834478

    申请日：2007-08-06

    申请人： Michael Edward Tuuk ,  Michael Clark

    发明人： Michael Edward Tuuk ,  Michael Clark

    IPC分类号： G06F12/00

    CPC分类号： G06F12/1036 ,  G06F2212/151 ,  G06F2212/681

    摘要： A data processing device employs a first translation look-aside buffer (TLB) to translate virtual addresses to physical addresses. If a virtual address to be translated is not located in the first TLB, the physical address is requested from a set of page tables. When the data processing device is in a hypervisor mode, a second TLB is accessed in response to the request to access the page tables. If the virtual address is located in the second TLB, the hypervisor page tables are bypassed and the second TLB provides a physical address or information to access another table in the set of page tables. By bypassing the hypervisor page tables, the time to translate an address in the hypervisor mode is reduced, thereby improving the efficiency of the data processing device.

    摘要翻译： 数据处理设备使用第一翻译后备缓冲器（TLB）将虚拟地址转换为物理地址。 如果要转换的虚拟地址不在第一个TLB中，则从一组页表请求物理地址。 当数据处理设备处于管理程序模式时，响应于访问页表的请求来访问第二TLB。 如果虚拟地址位于第二个TLB中，则管理程序页面表被绕过，第二个TLB提供物理地址或信息来访问该页表中的另一个表。 通过绕过虚拟机管理程序页面表，减少了管理程序模式中转换地址的时间，从而提高了数据处理设备的效率。