公开(公告)号：US20060072006A1

公开(公告)日：2006-04-06

申请号：US10958027

申请日：2004-10-05

Applicant: Lin Lin ,  Han Lin ,  Wun Wang

Inventor： Lin Lin ,  Han Lin ,  Wun Wang

IPC: H04N13/04 ,  H04N15/00

CPC classification number: H04N13/31

Abstract: A 3D stereo display method and a device thereof. Two sets of shutters are disposed in a display. The shutters are complementarily interlaced with each other. The opening/closing of the two sets of shutters are controlled by time interval concept. When the display frequency is odd frequency, one set of shutters is activated. When the display frequency is even frequency, the other set of shutters is activated. The two sets of shutters are continuously opened and closed according to the variation of the frequency so that in odd and even frequencies, the left and right eyes can respectively see independent images formed of different subpixels. Therefore, a 3D display effect is presented to bare eyes without reducing resolution.

Abstract translation: 一种3D立体显示方法及其装置。 两组百叶窗设在显示屏上。 百叶窗彼此互补交错。 两组百叶窗的打开/关闭由时间间隔概念控制。 当显示频率为奇数频率时，一组快门被激活。 当显示频率为均匀频率时，另一组快门被激活。 根据频率的变化，两组百叶窗连续地打开和关闭，使得在奇数和偶数频率下，左眼和右眼可以分别看到由不同子像素形成的独立图像。 因此，在不降低分辨率的情况下，将3D显示效果呈现给裸眼。

公开(公告)号：US6043271A

公开(公告)日：2000-03-28

申请号：US510213

申请日：1995-08-02

Applicant: Michael T. Flavin ,  Ze-Qi Xu ,  John D. Rizzo ,  Alla Kucherenko ,  Albert Khilevich ,  Abram Kivovich Sheinkman ,  Vilayphone Vilaychack ,  Lin Lin ,  Wei Chen ,  William A. Boulanger

Inventor： Michael T. Flavin ,  Ze-Qi Xu ,  John D. Rizzo ,  Alla Kucherenko ,  Albert Khilevich ,  Abram Kivovich Sheinkman ,  Vilayphone Vilaychack ,  Lin Lin ,  Wei Chen ,  William A. Boulanger

IPC: C07D311/58 ,  A61K31/365 ,  A61K45/06 ,  A61P31/12 ,  A61P37/04 ,  C07D311/16 ,  C07D493/04 ,  C07D493/14 ,  A61K31/35 ,  C07D407/00

CPC classification number: C07D493/04 ,  A61K45/06 ,  C07D311/16 ,  C07D493/14

Abstract: A method of preparing (.+-.)-calanolide A, 1, a potent HIV reverse transcriptase inhibitor, from chromene 4 is provided. Useful intermediates for preparing (.+-.)-calanolide A and its derivatives are also provided. According to the disclosed method, chromene 4 intermediate was reacted with acetaldehyde diethyl acetal or paraldehyde in the presence of an acid catalyst with heating, or a two-step reaction including an aldol reaction with acetaldehyde and cyclization either under acidic conditions or neutral Mitsunobu conditions, to produce chromanone 7. Reduction of chromanone 7 with sodium borohydride, in the presence of cerium trichloride, produced (.+-.)-calanolide A. A method for resolving (.+-.)-calanolide A into its optically active forms by a chiral HPLC system or by enzymatic acylation and hydrolysis is also disclosed. Finally, a method for treating or preventing a viral infections using (.+-.)-calanolide or (-)-calanolide is provided.

Abstract translation: 提供了从色烯4制备（+/-） - 丙内酰脲A，1，一种有效的HIV逆转录酶抑制剂的方法。 还提供了制备（+/-） - 丙内酰脲A及其衍生物的有用中间体。 根据所公开的方法，在酸催化剂的存在下，将色烯4中间体与乙醛二乙基缩醛或对甲醛反应，或者在酸性条件或中性Mitsunobu条件下，包括醛醇与乙醛反应和醛化反应的两步反应， 产生苯并二氢吡喃酮7.在三氯化铈的存在下，用硼氢化钠还原色酮7.产生（+/-） - 甘露糖苷A。一种通过手性拆分（+/-） - 卡立拉内酯A至其光学活性形式的方法 还公开了HPLC系统或通过酶酰化和水解。 最后，提供了使用（+/-） - 蒎烯内酯或（ - ） - 蒎烯内酯治疗或预防病毒感染的方法。

公开(公告)号：US5892060A

公开(公告)日：1999-04-06

申请号：US609537

申请日：1996-03-01

Applicant: Michael T. Flavin ,  Ze-Qi Xu ,  Albert Khilevich ,  David Zembower ,  John D. Rizzo ,  Shuyuan Liao ,  Aye Mar ,  Lin Lin ,  Vilayphone Vilaychak ,  Darko Brankovic ,  Sergey Dzekhster ,  Jinjun Liu

Inventor： Michael T. Flavin ,  Ze-Qi Xu ,  Albert Khilevich ,  David Zembower ,  John D. Rizzo ,  Shuyuan Liao ,  Aye Mar ,  Lin Lin ,  Vilayphone Vilaychak ,  Darko Brankovic ,  Sergey Dzekhster ,  Jinjun Liu

IPC: A61K45/06 ,  C07D311/16 ,  C07D493/04 ,  C07D493/14 ,  C07D407/14

CPC classification number: C07D493/04 ,  A61K45/06 ,  C07D311/16 ,  C07D493/14

Abstract: A method of preparing (+)-calanolide A, 1, a potent HIV reverse transcriptase inhibitor, from chromene 4 is provided. According to the disclosed method, chromene 4 intermediate was subjected to a chlorotitanium-mediated aldol reaction with acetaldehyde to selectively produce (.+-.)-8a. Separation and enzyme-mediated resolution of (.+-.)-8a produced (+)-8a. Cyclization of (+)-8a under neutral Mitsunobu conditions followed by Luche reduction of (+)-7 produced (+)-calanolide A in high yield and enantiomeric purity. The method of the invention has been extended to produce potent antiviral calanolide A analogues.

Abstract translation: 提供了从色烯4制备（+） - 丙内酰脲A，1，一种有效的HIV逆转录酶抑制剂的方法。 根据所公开的方法，将色烯4中间体与乙醛进行氯代钛介导的醛醇缩合反应以选择性地产生（+/-） - 8a。 （+） - 8a的（+/-） - 8a的分离和酶介导的分辨率。 （+） - 8a在中性Mitsunobu条件下循环，然后以高产率和对映异构体纯度，（+） - 7产生（+） - 卡立拉内酯A的Luche还原。 已经扩展了本发明的方法，以产生强效的抗病毒性甘露糖苷A类似物。

公开(公告)号：US5874591A

公开(公告)日：1999-02-23

申请号：US925707

申请日：1997-09-09

Applicant: Michael T. Flavin ,  Ze-Qi Xu ,  Vilayphone Vilaychack ,  Lin Lin

Inventor： Michael T. Flavin ,  Ze-Qi Xu ,  Vilayphone Vilaychack ,  Lin Lin

IPC: C07D311/58 ,  A61K31/365 ,  A61K45/06 ,  A61P31/12 ,  A61P37/04 ,  C07D311/16 ,  C07D493/04 ,  C07D493/14 ,  C07D493/00

CPC classification number: C07D493/04 ,  A61K45/06 ,  C07D311/16 ,  C07D493/14

Abstract: A method of preparing (.+-.)-calanolide A, 1, a potent HIV reverse transcriptase inhibitor, from chromene 4 is provided. Useful intermediates for preparing (.+-.)-calanolide A and its derivatives are also provided. According to the disclosed method, chromene 4 intermediate was reacted with acetaldehyde diethyl acetal or paraldehyde in the presence of an acid catalyst with heating, or a two-step reaction including an aldol reaction with acetaldehyde and cyclization either under acidic conditions or neutral Mitsunobu conditions, to produce chromanone 7. Reduction of chromanone 7 with sodium borohydride, in the presence of cerium trichloride, produced (.+-.)-calanolide A. A method for resolving (.+-.)-calanolide A into its optically active forms by a chiral HPLC system or by enzymatic acylation and hydrolysis is also disclosed. Finally, a method for treating or preventing viral infections using (.+-.)-calanolide A or (-)-calanolide A is provided.

公开(公告)号：US5872264A

公开(公告)日：1999-02-16

申请号：US924803

申请日：1997-09-05

Applicant: Michael T. Flavin ,  Ze-Qi Xu ,  Albert Khilevich ,  David Zembower ,  John D. Rizzo ,  Shuyuan Liao ,  Aye Mar ,  Lin Lin ,  Vilayphone Vilaychack ,  Darko Brankovic ,  Sergey Dzekhster ,  Jinjun Liu

Inventor： Michael T. Flavin ,  Ze-Qi Xu ,  Albert Khilevich ,  David Zembower ,  John D. Rizzo ,  Shuyuan Liao ,  Aye Mar ,  Lin Lin ,  Vilayphone Vilaychack ,  Darko Brankovic ,  Sergey Dzekhster ,  Jinjun Liu

IPC: A61K45/06 ,  C07D311/16 ,  C07D493/04 ,  C07D493/14 ,  C07D493/22

CPC classification number: C07D493/04 ,  A61K45/06 ,  C07D311/16 ,  C07D493/14

Abstract: A method of preparing (+)-calanolide A, 1, a potent HIV reverse transcriptase inhibitor, from chromene 4 is provided. According to the disclosed method, chromene 4 intermediate was subjected to a chlorotitanium-mediated aldol reaction with acetaldehyde to selectively produce (.+-.)-8a. Separation and enzyme-mediated resolution of (.+-.)-8a produced (+)-8a. Cyclization of (+)-8a under neutral Mitsunobu conditions followed by Luche reduction of (.+-.)-7 produced (+)-calanolide A in high yield and enantiomeric purity. The method of the invention has been extended to produce potent antiviral calanolide A analogues.

Abstract translation: 提供了从色烯4制备（+） - 丙内酰脲A，1，一种有效的HIV逆转录酶抑制剂的方法。 根据所公开的方法，将色烯4中间体与乙醛进行氯代钛介导的醛醇缩合反应以选择性地产生（+/-） - 8a。 （+） - 8a的（+/-） - 8a的分离和酶介导的分辨率。 在中性Mitsunobu条件下环化（+） - 8a，然后以高产率和对映体纯度，（+/-） - 7产生（+） - 卡立拉内酯A的Luche还原。 已经扩展了本发明的方法，以产生强效的抗病毒性甘露糖苷A类似物。

公开(公告)号：US10302876B2

公开(公告)日：2019-05-28

申请号：US13398312

申请日：2012-02-16

Applicant: Soren Grinderslev ,  Lin Lin

Inventor： Soren Grinderslev ,  Lin Lin

IPC: G02B6/36 ,  G02B6/38 ,  G02B6/32

Abstract: A connector comprising a first outer housing defining at least one cavity, the cavity being cylindrical, a first insert disposed in the cavity, the first insert comprising at least a first housing, the housing being cylindrical, a first ferrule in the first housing, the first ferrule configured with arcuate sides to be received in the cavity, the first ferule comprising an end face, at least one alignment hole for receiving an alignment pin defined in the end face, and at least one fiber-receiving channel for receiving an optical fiber, an optical fiber disposed in the fiber-receiving channel of the first ferrule.

公开(公告)号：US09844728B2

公开(公告)日：2017-12-19

申请号：US14358967

申请日：2011-12-16

Applicant: Jinming Cao ,  Lin Hou ,  Chao Guo ,  Xingguang Yu ,  Huiqiang Liu ,  Kerry Yang ,  Lin Lin

Inventor： Jinming Cao ,  Lin Hou ,  Chao Guo ,  Xingguang Yu ,  Huiqiang Liu ,  Kerry Yang ,  Lin Lin

IPC: A63F9/24 ,  A63F13/00 ,  G06F17/00 ,  G06F19/00 ,  A63F13/79 ,  H04L12/58 ,  A63F13/30

CPC classification number: A63F13/79 ,  A63F13/12 ,  A63F13/34 ,  A63F2300/5546 ,  A63F2300/57 ,  H04L51/32

Abstract: An apparatus and method for providing social network content in an online game is disclosed herein. Content is obtained from a social network site and is displayed within the game. The game also provides a mechanism for the user of the game to generate content to the posted within the social network from within the game. Such generated content is automatically posted in the social network for a recipient specified by the user.

公开(公告)号：US09082409B2

公开(公告)日：2015-07-14

申请号：US12200384

申请日：2008-08-28

Applicant: Lin Lin ,  Ping Lin

Inventor： Lin Lin ,  Ping Lin

IPC: G10L21/00 ,  G10L25/00 ,  G06F17/00 ,  G06F17/20 ,  G06F3/00 ,  G06F17/21 ,  G06F17/22 ,  G06F17/24 ,  G06F17/25 ,  G06F17/26 ,  G06F17/27 ,  G06F17/28

CPC classification number: G06F3/167 ,  G06F17/00 ,  G06F17/2247 ,  G10L21/00 ,  G10L2015/228

Abstract: A method, system and voice browser execute voice applications to perform a voice-based function. A document is retrieved and parsed to create a parse tree. Script code is created from the parse tree, thereby consuming part of the parse tree to create a reduced parse tree. The reduced parse tree is stored in a cache for subsequent execution to perform the voice-based function.

Abstract translation: 一种方法，系统和语音浏览器执行语音应用来执行基于语音的功能。 检索并解析文档以创建解析树。 脚本代码是从解析树创建的，从而消耗部分解析树以创建一个简化的分析树。 缩减的分析树被存储在高速缓存中以便随后执行以执行基于语音的功能。

公开(公告)号：US08964029B2

公开(公告)日：2015-02-24

申请号：US11919541

申请日：2005-04-29

Applicant: Alan M. Finn ,  Pengju Kang ,  Ziyou Xiong ,  Lin Lin ,  Pei-Yuan Peng ,  Meghna Misra ,  Christian Maria Netter

Inventor： Alan M. Finn ,  Pengju Kang ,  Ziyou Xiong ,  Lin Lin ,  Pei-Yuan Peng ,  Meghna Misra ,  Christian Maria Netter

IPC: H04N7/18 ,  G06K9/36 ,  G08B13/196

CPC classification number: G08B13/19652 ,  G06K9/00771 ,  G08B13/1963 ,  G08B13/19689

Abstract: The present invention describes a system and method for surveillance cameras that maintain proper mapping of a mapped region of interest with an imaged region of interest based on feedback received regarding the current orientation of a surveillance camera. The system or method first determines the location of the imaged region of interest within the surveillance camera's imaged current field of view based on mechanical or imaged feedback, or a combination of both. The system or method then remaps the mapped region of interest within the surveillance camera's imaged current field of view such that the mapped region of interest is coextensive with the imaged region of interest.

公开(公告)号：US20130216189A1

公开(公告)日：2013-08-22

申请号：US13398312

申请日：2012-02-16

Applicant: Soren Grinderslev ,  Lin Lin

Inventor： Soren Grinderslev ,  Lin Lin

IPC: G02B6/36

CPC classification number: G02B6/3879 ,  G02B6/32 ,  G02B6/3672 ,  G02B6/3825 ,  G02B6/3885

Abstract: A connector comprising a first outer housing defining at least one cavity, the cavity being cylindrical, a first insert disposed in the cavity, the first insert comprising at least a first housing, the housing being cylindrical, a first ferrule in the first housing, the first ferrule configured with arcuate sides to be received in the cavity, the first ferule comprising an end face, at least one alignment hole for receiving an alignment pin defined in the end face, and at least one fiber-receiving channel for receiving an optical fiber, an optical fiber disposed in the fiber-receiving channel of the first ferrule.

Abstract translation: 一种连接器，包括限定至少一个空腔的第一外壳，所述空腔是圆柱形的，设置在所述空腔中的第一插入件，所述第一插入件包括至少第一壳体，所述壳体是圆柱形的，所述第一壳体中的第一套圈， 第一套圈构造成具有弓形侧面以容纳在空腔中，第一微细小孔包括端面，用于接收限定在端面中的对准销的至少一个对准孔以及用于接收光纤的至少一个光纤接收通道 ，设置在第一套圈的光纤接收通道中的光纤。