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公开(公告)号：US07385031B2
公开(公告)日：2008-06-10
申请号：US10145632
申请日：2002-05-14
申请人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
发明人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC分类号： C07K14/705
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K39/0011 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/4703 , C07K14/705 , C07K14/70578 , C07K14/82 , C07K16/18 , C07K17/00 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N5/06 , C12N9/00 , C12N9/001 , C12N9/1051 , C12N15/00 , C12N2799/026 , C12P21/02 , C12P21/06 , C12Q1/68 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5008 , G01N33/5011 , G01N33/5014 , G01N33/502 , G01N33/5044 , G01N33/505 , G01N33/5061 , G01N33/53 , G01N33/574 , G01N33/57484 , G01N33/68 , G01N33/6845 , G01N2800/042 , Y10S530/828 , Y10S530/866
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07307152B2
公开(公告)日：2007-12-11
申请号：US10970823
申请日：2004-10-20
申请人： Luc Desnoyers , Napoleone Ferrara , Ellen Filvaroff , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , William I. Wood
发明人： Luc Desnoyers , Napoleone Ferrara , Ellen Filvaroff , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , William I. Wood
CPC分类号： C07K14/47
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US07291704B2
公开(公告)日：2007-11-06
申请号：US10184651
申请日：2002-06-27
申请人： Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
发明人： Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
CPC分类号： C07K14/47 , A01K2217/075 , A01K2227/105 , A61K38/00 , A61K39/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/00 , C07K16/18 , C07K16/28 , C07K2319/30 , C12N9/90 , C12N2799/026 , C12Q1/6816 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5082 , G01N33/5308 , G01N33/574 , G01N33/57411 , G01N33/57415 , G01N33/57419 , G01N33/57423 , G01N33/57434 , G01N33/57484 , G01N33/57488 , G01N33/57492 , G01N2500/10 , C12Q2563/131 , C12Q2527/137
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07276578B2
公开(公告)日：2007-10-02
申请号：US10187757
申请日：2002-07-01
申请人： Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
发明人： Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC分类号： C07K1/00
CPC分类号： C07K14/47 , A01K2217/075 , A01K2227/105 , A61K38/00 , A61K39/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/00 , C07K16/18 , C07K16/28 , C07K2319/30 , C12N9/90 , C12N2799/026 , C12Q1/6816 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5082 , G01N33/5308 , G01N33/574 , G01N33/57411 , G01N33/57415 , G01N33/57419 , G01N33/57423 , G01N33/57434 , G01N33/57484 , G01N33/57488 , G01N33/57492 , G01N2500/10 , C12Q2563/131 , C12Q2527/137
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07256039B2
公开(公告)日：2007-08-14
申请号：US10036150
申请日：2001-12-26
CPC分类号： C07K14/47 , A61K38/00 , C07K14/4703 , C07K14/52 , C07K14/54 , C07K14/545 , C07K14/70578 , C07K16/18 , C07K2317/24 , C07K2319/00 , C12N2799/026
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07208308B2
公开(公告)日：2007-04-24
申请号：US09903640
申请日：2001-07-11
申请人： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Giang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
发明人： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Giang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC分类号： C12N9/48
CPC分类号： C07K14/47 , G01N33/68 , G01N2333/485
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US07105639B2
公开(公告)日：2006-09-12
申请号：US10035855
申请日：2001-12-26
IPC分类号： C07K16/28
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07101687B2
公开(公告)日：2006-09-05
申请号：US09991157
申请日：2001-11-16
CPC分类号： C07K14/71
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07070955B2
公开(公告)日：2006-07-04
申请号：US09989733
申请日：2001-11-20
申请人： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
发明人： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
CPC分类号： C07K14/4747 , C07K14/47
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US07041804B2
公开(公告)日：2006-05-09
申请号：US09990441
申请日：2001-11-16
申请人： Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Colin K. Watanabe , William I. Wood
发明人： Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Colin K. Watanabe , William I. Wood
IPC分类号： C07K16/00 , C07K16/18 , A61K39/395 , C12P21/08
CPC分类号： C07K14/47 , C07K14/4713
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising these nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含这些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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