专利检索 ap:"Laura DeForge" 第 1 页

1.

发明申请
Anti-factor B antibodies and their uses 有权
标题翻译：抗因子B抗体及其用途

公开(公告)号：US20090123469A1

公开(公告)日：2009-05-14

申请号：US12291222

申请日：2008-11-06

申请人： Menno Van Lookeren Campagne , Laura Deforge

发明人： Menno Van Lookeren Campagne , Laura Deforge

IPC分类号： A61K39/395 , C07K16/18 , A61K38/02

CPC分类号： C07K16/40 , C07K2317/56 , C07K2317/76

摘要： The invention concerns the prevention and treatment of complement-associated eye conditions, such as choroidal neovascularization (CNV) and age-related macular degeneration (AMD), by administration of factor B antagonists.

摘要翻译： 本发明涉及通过施用因子B拮抗剂来预防和治疗补体相关眼病，例如脉络膜新生血管形成（CNV）和年龄相关性黄斑变性（AMD）。

2.

发明授权
PRO1475 polypeptide 有权
标题翻译： PRO1475多肽

公开(公告)号：US07432345B2

公开(公告)日：2008-10-07

申请号：US10127836

申请日：2002-04-22

申请人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang

发明人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang

IPC分类号： C07K1/00

CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K39/0011 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/4703 , C07K14/705 , C07K14/70578 , C07K14/82 , C07K16/18 , C07K17/00 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N5/06 , C12N9/00 , C12N9/001 , C12N9/1051 , C12N15/00 , C12N2799/026 , C12P21/02 , C12P21/06 , C12Q1/68 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5008 , G01N33/5011 , G01N33/5014 , G01N33/502 , G01N33/5044 , G01N33/505 , G01N33/5061 , G01N33/53 , G01N33/574 , G01N33/57484 , G01N33/68 , G01N33/6845 , G01N2800/042 , Y10S530/828 , Y10S530/866

摘要： The present invention is directed to novel PRO1475 polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the PRO1475 polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the PRO1475 polypeptides of the present invention and to methods for producing the PRO1475 polypeptides of the present invention.

摘要翻译： 本发明涉及新型PRO1475多肽和编码那些多肽的核酸分子。本文还提供了包含这些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的PRO1475多肽的嵌合多肽分子，与本发明的PRO1475多肽结合的抗体和用于产生PRO1475多肽的方法的本发明。

3.

发明授权
Anti-PRO6181 antibodies 有权
标题翻译：抗PRO6181抗体

公开(公告)号：US07408042B2

公开(公告)日：2008-08-05

申请号：US10145958

申请日：2002-05-14

申请人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang

发明人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang

IPC分类号： C07K16/18

CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K39/0011 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/4703 , C07K14/705 , C07K14/70578 , C07K14/82 , C07K16/18 , C07K17/00 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N5/06 , C12N9/00 , C12N9/001 , C12N9/1051 , C12N15/00 , C12N2799/026 , C12P21/02 , C12P21/06 , C12Q1/68 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5008 , G01N33/5011 , G01N33/5014 , G01N33/502 , G01N33/5044 , G01N33/505 , G01N33/5061 , G01N33/53 , G01N33/574 , G01N33/57484 , G01N33/68 , G01N33/6845 , G01N2800/042 , Y10S530/828 , Y10S530/866

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

4.

发明授权
PRO6097 polypeptides 有权
标题翻译： PRO6097多肽

公开(公告)号：US07385031B2

公开(公告)日：2008-06-10

申请号：US10145632

申请日：2002-05-14

申请人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang

发明人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang

IPC分类号： C07K14/705

CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K39/0011 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/4703 , C07K14/705 , C07K14/70578 , C07K14/82 , C07K16/18 , C07K17/00 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N5/06 , C12N9/00 , C12N9/001 , C12N9/1051 , C12N15/00 , C12N2799/026 , C12P21/02 , C12P21/06 , C12Q1/68 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5008 , G01N33/5011 , G01N33/5014 , G01N33/502 , G01N33/5044 , G01N33/505 , G01N33/5061 , G01N33/53 , G01N33/574 , G01N33/57484 , G01N33/68 , G01N33/6845 , G01N2800/042 , Y10S530/828 , Y10S530/866

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

5.

发明申请
SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME 审中-公开
标题翻译：分泌和转运蛋白多核苷酸和编码其的核酸

公开(公告)号：US20070264686A1

公开(公告)日：2007-11-15

申请号：US11553810

申请日：2006-10-27

申请人： Kevin Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary Gerritsen , Audrey Goddard , Paul Godowski , Austin Gurney , Steven Sherwood , Victoria Smith , Timothy Stewart , Daniel Tumas , Colin Watanabe , William Wood , Zemin Zhang

发明人： Kevin Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary Gerritsen , Audrey Goddard , Paul Godowski , Austin Gurney , Steven Sherwood , Victoria Smith , Timothy Stewart , Daniel Tumas , Colin Watanabe , William Wood , Zemin Zhang

IPC分类号： C07H21/04 , C12P21/06 , C12N9/00 , C07K14/47 , C07K16/18

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

6.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 审中-公开

公开(公告)号：US20050019823A1

公开(公告)日：2005-01-27

申请号：US10931886

申请日：2004-08-31

申请人： Kevin Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary Gerritsen , Audrey Goddard , Paul Godowski , Austin Gurney , Steven Sherwood , Victoria Smith , Timothy Stewart , Daniel Tumas , Colin Watanabe , William Wood , Zemin Zhang

发明人： Kevin Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary Gerritsen , Audrey Goddard , Paul Godowski , Austin Gurney , Steven Sherwood , Victoria Smith , Timothy Stewart , Daniel Tumas , Colin Watanabe , William Wood , Zemin Zhang

IPC分类号： A61K38/00 , A61K38/17 , C07H21/02 , C07H21/04 , C07K1/00 , C07K14/00 , C07K14/435 , C07K14/47 , C07K14/705 , C07K16/18 , C07K17/00 , C12N5/06 , C12N9/00 , C12N9/02 , C12N15/00 , C12N15/12 , C12P21/02 , C12P21/06 , C12Q1/68 , C12Q1/6886 , G01N33/53 , G01N33/574 , G01N33/68 , C12P21/04

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

7.

发明申请
POLYPEPTIDES THAT BIND BR3 AND USES THEREOF 审中-公开
标题翻译：聚合BR3并使用它

公开(公告)号：US20100280227A1

公开(公告)日：2010-11-04

申请号：US12835570

申请日：2010-07-13

申请人： CHRISTINE M. AMBROSE , MERCEDESZ BALAZS , LAURA DEFORGE , MARK S. DENNIS , GERMAINE FUH , STEPHEN D. HURST , CHINGWEI V. LEE , HENRY B. LOWMAN , FLAVIUS MARTIN , GERALD R. NAKAMURA , DHAYA SESHASAYEE , MELISSA A. STAROVASNIK , JEFFREY S. THOMPSON

发明人： CHRISTINE M. AMBROSE , MERCEDESZ BALAZS , LAURA DEFORGE , MARK S. DENNIS , GERMAINE FUH , STEPHEN D. HURST , CHINGWEI V. LEE , HENRY B. LOWMAN , FLAVIUS MARTIN , GERALD R. NAKAMURA , DHAYA SESHASAYEE , MELISSA A. STAROVASNIK , JEFFREY S. THOMPSON

IPC分类号： C07K16/18

CPC分类号： C07K16/2878 , C07K2317/34 , C07K2317/732

摘要： The present invention relates to novel BR3 binding antibodies and polypeptides, including antagonist and agonist polypeptides. The present invention also relates to the use of the BR3 binding antibodies and polypeptides in, e.g., methods of treatment, screening methods, diagnostic methods, assays and protein purification methods.

摘要翻译： 本发明涉及新型BR3结合抗体和多肽，包括拮抗剂和激动剂多肽。本发明还涉及例如治疗方法，筛选方法，诊断方法，测定和蛋白质纯化方法中BR3结合抗体和多肽的用途。

8.

发明申请
Polypeptides That Bind Br3 and Uses Thereof 审中-公开
标题翻译：绑定Br3的多肽及其用途

公开(公告)号：US20080181888A1

公开(公告)日：2008-07-31

申请号：US11793946

申请日：2005-12-23

申请人： Christine M. Ambrose , Mercedesz Balazs , Laura DeForge , Mark S. Dennis , Germaine Fuh , Stephen D. Hurst , Chingwei V. Lee , Henry B. Lowman , Flavius Martin , Gerald R. Nakamura , Dhaya Seshasayee , Melissa Starovasnik , Jeffrey S. Thompson

发明人： Christine M. Ambrose , Mercedesz Balazs , Laura DeForge , Mark S. Dennis , Germaine Fuh , Stephen D. Hurst , Chingwei V. Lee , Henry B. Lowman , Flavius Martin , Gerald R. Nakamura , Dhaya Seshasayee , Melissa Starovasnik , Jeffrey S. Thompson

IPC分类号： A61K39/395 , C07K16/18 , C12N15/11 , C12N15/00 , A61P43/00 , C12N5/06 , C12P21/04

CPC分类号： C07K16/2878 , C07K2317/34 , C07K2317/732

摘要： The present invention relates to novel BR3 binding antibodies and polypeptides, including antagonist and agonist polypeptides. The present invention also relates to the use of the BR3 binding antibodies and polypeptides in, e.g., methods of treatment, screening methods, diagnostic methods, assays and protein purification methods.

摘要翻译： 本发明涉及新型BR3结合抗体和多肽，包括拮抗剂和激动剂多肽。本发明还涉及例如治疗方法，筛选方法，诊断方法，测定和蛋白质纯化方法中BR3结合抗体和多肽的用途。