N-end rule pathway enzymes
    62.
    发明授权
    N-end rule pathway enzymes 失效
    N端规则途径酶

    公开(公告)号:US06297034B1

    公开(公告)日:2001-10-02

    申请号:US09370807

    申请日:1999-08-09

    IPC分类号: C12N910

    摘要: This invention relates to an isolated nucleic acid fragment encoding an enzyme involved in the N-end rule pathway of protein degradation. The invention also relates to the construction of a chimeric gene encoding all or a portion of the enzyme involved in the N-end rule pathway of protein degradation, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the enzyme involved in the N-end rule pathway of protein degradation in a transformed host cell.

    摘要翻译: 本发明涉及编码参与蛋白质降解的N端规则途径的酶的分离的核酸片段。 本发明还涉及在正义或反义方向上构建编码参与蛋白质降解的N端规则途径的全部或部分酶的嵌合基因,其中嵌合基因的表达导致产生改变的水平 涉及转化宿主细胞中蛋白质降解的N端规则途径的酶。