Insulin receptor tyrosine kinase substrate
    61.
    发明授权
    Insulin receptor tyrosine kinase substrate 失效
    胰岛素受体酪氨酸激酶底物

    公开(公告)号:US06589935B1

    公开(公告)日:2003-07-08

    申请号:US09046572

    申请日:1998-03-23

    IPC分类号: C12N1500

    CPC分类号: C07K14/47 A61K38/00

    摘要: The invention provides a human insulin receptor tyrosine kinase substrate (IRS-p53h) and polynucleotides which identify and encode IRS-p53h. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of IRS-p53h.

    摘要翻译: 本发明提供了人胰岛素受体酪氨酸激酶底物(IRS-p53h)和鉴定和编码IRS-p53h的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与IRS-p53h表达相关的疾病的方法。

    Human reticulocalbin isoforms
    65.
    发明授权
    Human reticulocalbin isoforms 失效
    人reticulocalbin同种型

    公开(公告)号:US06235477B1

    公开(公告)日:2001-05-22

    申请号:US09270270

    申请日:1999-03-16

    IPC分类号: C12Q168

    摘要: The invention provides two human reticulocalbin isoforms designated individually as RCN &ggr; and RCN &dgr; and collectively as RCN, and polynucleotides which identify and encode RCN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of RCN.

    摘要翻译: 本发明提供了两种单独指定为RCNγ和RCNδ并统称为RCN的人reticulocalbin同种型,以及识别和编码RCN的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与RCN表达相关的疾病的方法。