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公开(公告)号:US5885803A
公开(公告)日:1999-03-23
申请号:US878989
申请日:1997-06-19
申请人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides human disease associated protein kinases and polynucleotides (collectively designated DAPK) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human disease associated protein kinases.
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公开(公告)号:US5854022A
公开(公告)日:1998-12-29
申请号:US855140
申请日:1997-05-13
IPC分类号: C12N15/09 , A61K38/00 , A61K39/395 , A61K45/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12P21/02 , C12Q1/02 , C12Q1/68 , C07H21/04
CPC分类号: C07K14/70596 , A61K38/00
摘要: The present invention provides a human transmembrane protein (ONMO) and polynucleotides which identify and encode ONMO. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing ONMO and for treating or preventing disorders associated with expression of ONMO.
摘要翻译: 本发明提供了人跨膜蛋白(ONMO)和识别和编码ONMO的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 此外,本发明提供了用于生产ONMO和用于治疗或预防与ONMO表达相关的病症的方法。
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公开(公告)号:US06207148B1
公开(公告)日:2001-03-27
申请号:US09272796
申请日:1999-03-19
申请人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
IPC分类号: A61K3843
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides human disease associated protein kinases and polynucleotides (collectively designated DAPK) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human disease associated protein kinases.
摘要翻译: 本发明提供了识别和编码它们的人类疾病相关蛋白激酶和多核苷酸(统称为DAPK)。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供用于诊断和治疗与人类疾病相关蛋白激酶的表达相关的疾病的方法。
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公开(公告)号:US6156523A
公开(公告)日:2000-12-05
申请号:US153939
申请日:1998-09-16
申请人: Olga Bandman , Y. Tom Tang , Surya K. Goli , Neil C. Corley , Karl J. Guegler , Gina A. Gorgone , Jennifer L. Hillman
发明人: Olga Bandman , Y. Tom Tang , Surya K. Goli , Neil C. Corley , Karl J. Guegler , Gina A. Gorgone , Jennifer L. Hillman
IPC分类号: C12N15/09 , A61K38/00 , A61K38/45 , A61K45/00 , A61P1/00 , A61P1/18 , A61P3/00 , A61P3/10 , A61P5/14 , A61P5/38 , A61P7/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P13/12 , A61P15/08 , A61P17/00 , A61P17/06 , A61P19/02 , A61P19/10 , A61P25/00 , A61P25/08 , A61P27/02 , A61P27/06 , A61P27/12 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P33/00 , A61P35/00 , A61P37/00 , A61P37/04 , A61P37/08 , A61P43/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/54 , C12Q1/68 , A61K38/43 , C07K14/00 , C12N9/00 , C12N15/52 , G01N23/53
CPC分类号: C12N9/1205 , C12Y207/01037 , A61K38/00
摘要: The invention provides human serine/threonine protein kinases (HSTK) and polynucleotides which identify and encode HSTK. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HSTK.
摘要翻译: 本发明提供人丝氨酸/苏氨酸蛋白激酶(HSTK)和识别和编码HSTK的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSTK表达相关的病症的方法。
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公开(公告)号:US08153398B2
公开(公告)日:2012-04-10
申请号:US12457389
申请日:2009-06-09
申请人: Preeti G. Lal , Y. Tom Tang , Gina A. Gorgone Simone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice K. Au-Young , Henry Yue , Chandra S. Arvizu , Roopa M. Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti G. Lal , Y. Tom Tang , Gina A. Gorgone Simone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice K. Au-Young , Henry Yue , Chandra S. Arvizu , Roopa M. Reddy , Jennifer L. Hillman , Olga Bandman
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US20110053217A1
公开(公告)日:2011-03-03
申请号:US12457389
申请日:2009-06-09
申请人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
IPC分类号: C12P21/00 , C07H21/04 , C12N1/21 , C07H21/02 , C07K14/435
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US07045333B1
公开(公告)日:2006-05-16
申请号:US09659151
申请日:2000-09-11
申请人: Olga Bandman , Jennifer L. Hillman , Henry Yue , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Henry Yue , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
CPC分类号: C12N9/6424 , A61K38/00 , C07K16/40 , C12N9/48 , C12N9/6472 , C12N9/6478
摘要: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
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公开(公告)号:US06232454B1
公开(公告)日:2001-05-15
申请号:US09032523
申请日:1998-02-27
IPC分类号: C07H2102
CPC分类号: C12N9/6472 , A61K38/00 , C07K14/4705 , C12N9/6478
摘要: The invention provides human proteinase molecules (HPRM) and polynucleotides which identify and encode HPRM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPRM.
摘要翻译: 本发明提供鉴定和编码HPRM的人类蛋白酶分子(HPRM)和多核苷酸。 本发明还提供了表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与HPRM表达相关的疾病的方法。
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公开(公告)号:US6008337A
公开(公告)日:1999-12-28
申请号:US32372
申请日:1998-02-27
申请人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Henry Yue , Preeti Lal
发明人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Henry Yue , Preeti Lal
IPC分类号: C12N15/09 , A61K38/00 , A61K39/395 , A61P35/00 , A61P37/02 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/14 , C12N15/12 , C12N15/55 , C12P21/02 , C12Q1/68 , C07H21/04 , C07H21/02
CPC分类号: C07K14/4738 , C07K14/47 , C12N9/14 , A61K38/00
摘要: The invention provides human cell cycle related proteins (CCRP) and polynucleotides which identify and encode CCRP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of CCRP.
摘要翻译: 本发明提供识别和编码CCRP的人类细胞周期相关蛋白(CCRP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与CCRP表达相关的病症的方法。
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公开(公告)号:US5945306A
公开(公告)日:1999-08-31
申请号:US991946
申请日:1997-12-16
摘要: The invention provides two human Ras proteins, referred to collectively as "RAPR" and individually as "RAPR-1" and "RAPR-2", and polynucleotides which identify and encode RAPR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of RAPR.
摘要翻译: 本发明提供两种人类Ras蛋白质,统称为“RAPR”,分别称为“RAPR-1”和“RAPR-2”,以及鉴定和编码RAPR的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了预防和治疗与RAPR表达相关的疾病的方法。
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