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    SYSTEM AND METHOD FOR MULTI-IMAGE BASED STENT VISIBILITY ENHANCEMENT
    63.
    发明申请
    SYSTEM AND METHOD FOR MULTI-IMAGE BASED STENT VISIBILITY ENHANCEMENT 有权
    用于基于多图像的视觉可视性增强的系统和方法

    公开(公告)号：US20110064285A1

    公开(公告)日：2011-03-17

    申请号：US12846273

    申请日：2010-07-29

    申请人： Yunqiang Chen ,  Ti-chiun Chang ,  Michelle Xiaohong Yan ,  Tong Fang ,  Thomas Pohl ,  Stefan Böhm ,  Peter Durlak ,  Markus Roßmeier

    发明人： Yunqiang Chen ,  Ti-chiun Chang ,  Michelle Xiaohong Yan ,  Tong Fang ,  Thomas Pohl ,  Stefan Böhm ,  Peter Durlak ,  Markus Roßmeier

    IPC分类号： G06K9/00

    CPC分类号： G06K9/6206 ,  G06K2209/057 ,  G06T5/001 ,  G06T5/20 ,  G06T5/50 ,  G06T2207/10016 ,  G06T2207/10121 ,  G06T2207/30101

    摘要： A method for enhancing stent visibility in digital medical images includes providing a time series of 2-dimensional (2D) images of a stent in a vessel, estimating motion of the stent in a subset of images of the time series of images, estimating motion of clutter in the subset of images, where clutter comprises anatomical structures other than the stent, estimating a clutter layer in the subset of images from the estimated clutter motion, estimating a stent layer in the subset of images from the clutter layer and the estimated clutter motion, and minimizing a functional of the estimated stent motion, the estimated stent layer, the estimated clutter motion, and the estimated clutter layer to in calculate a refined stent layer image, where the refined stent layer image has enhanced visibility of the stent.

    摘要翻译： 一种用于增强数字医学图像中的支架可视性的方法包括在血管中提供支架的二维（2D）图像的时间序列，估计支架在时间序列图像的图像的子集中的运动，估计运动 在图像子集中混乱，其中杂波包括除了支架之外的解剖结构，从估计的杂波运动估计图像子集中的杂波层，估计来自杂波层的图像子集中的支架层和估计的杂波运动 并且在计算精制的支架层图像时，将精确的支架层图像具有增强的支架的可视性，并且将估计的支架运动，估计的支架层，估计的杂波运动和估计的杂波层的功能最小化。

    System and method for statistical shape model based segmentation of intravascular ultrasound and optical coherence tomography images
    65.
    发明授权
    System and method for statistical shape model based segmentation of intravascular ultrasound and optical coherence tomography images 有权
    用于基于统计形态模型的血管内超声和光学相干断层扫描图像分割的系统和方法

    公开(公告)号：US07831078B2

    公开(公告)日：2010-11-09

    申请号：US11779413

    申请日：2007-07-18

    申请人： Gozde Unal ,  Susann Bucher ,  Gregory G. Slabaugh ,  Tong Fang

    发明人： Gozde Unal ,  Susann Bucher ,  Gregory G. Slabaugh ,  Tong Fang

    IPC分类号： G06K9/00

    CPC分类号： G06K9/621 ,  G06K2209/05 ,  G06T7/12 ,  G06T7/149 ,  G06T7/174 ,  G06T2207/10081 ,  G06T2207/10132 ,  G06T2207/30101 ,  Y10S128/922

    摘要： A method for segmenting intravascular images includes acquiring a series of digitized images acquired from inside a vessel, each said image comprising a plurality of intensities corresponding to a 2-dimensional grid of pixels, providing a precomputed set of shapes for modeling contours of vessel wall boundaries, wherein a contour can be expressed as a sum of a mean shape and a inner product of shape modes and shape weights, initializing a boundary contour for one of said set of images, initializing said shape weights by projecting a contour into said shape modes, updating said shape weights from differential equations of said shape weights, and computing a contour by summing said mean shape and said inner product of shape modes and updated shape weights.

    摘要翻译： 用于分割血管内图像的方法包括获取从血管内获取的一系列数字化图像，每个所述图像包括对应于像素的二维网格的多个强度，提供用于建模血管壁边界的轮廓的预先计算的一组形状 其中轮廓可以表示为平均形状和形状模式和形状权重的内积的和，初始化所述图像集合中的一个图像的边界轮廓，通过将轮廓投影到所述形状模式中来初始化所述形状权重， 从所述形状权重的微分方程更新所述形状权重，以及通过将所述平均形状和形状模式的内积与更新的形状权重相加来计算轮廓。

    WATER-SOLUBLE TRITERPENEPHENOL COMPOUNDS HAVING ANTITUMOR ACTIVITY AND THE PREPARATION THEREOF
    66.
    发明申请
    WATER-SOLUBLE TRITERPENEPHENOL COMPOUNDS HAVING ANTITUMOR ACTIVITY AND THE PREPARATION THEREOF 有权
    具有抗肿瘤活性的水溶性三羟甲基苯酚化合物及其制备方法

    公开(公告)号：US20100267983A1

    公开(公告)日：2010-10-21

    申请号：US12743101

    申请日：2008-11-05

    申请人： Jiafeng Zeng ,  Junfang Pan ,  Baoying Li ,  Qin Zhu ,  Tong Fang ,  Huiyan Ni

    发明人： Jiafeng Zeng ,  Junfang Pan ,  Baoying Li ,  Qin Zhu ,  Tong Fang ,  Huiyan Ni

    IPC分类号： C07C309/60 ,  C07C69/753

    CPC分类号： C07J63/00 ,  C07J63/008

    摘要： The invention discloses water-soluble triterpenephenol compounds having antitumor activity represented by formula (I), wherein the substituents R1˜R4 and M are defined as in the description. The invention also discloses a method for preparing the compounds of formula (I) used quinone methide triterpene compounds as starting materials. The water-soluble triterpenephenol compounds disclosed in the invention can be made into various dosage forms including injection, tablet, capsule, granule and liniment, particularly suitable for making into injection.

    摘要翻译： 本发明公开了具有由式（I）表示的抗肿瘤活性的水溶性三硝基苯酚化合物，其中取代基R 1〜R 4和M如说明书中所定义。 本发明还公开了使用醌甲基化三萜化合物作为原料制备式（I）化合物的方法。 本发明公开的水溶性三萜烯化合物可以制成各种剂型，包括注射剂，片剂，胶囊剂，颗粒剂和搽剂，特别适用于注射。

    METHOD FOR CORRECTING MOTION ARTIFACTS IN MAGNETIC RESONANCE IMAGES
    67.
    发明申请
    METHOD FOR CORRECTING MOTION ARTIFACTS IN MAGNETIC RESONANCE IMAGES 有权
    用于校正磁共振图像中的运动文学的方法

    公开(公告)号：US20100142789A1

    公开(公告)日：2010-06-10

    申请号：US12632240

    申请日：2009-12-07

    申请人： Ti-chiun Chang ,  Tong Fang ,  Michelle Xiaohong Yan

    发明人： Ti-chiun Chang ,  Tong Fang ,  Michelle Xiaohong Yan

    IPC分类号： G06K9/00 ,  A61B5/055

    CPC分类号： A61B6/03 ,  A61B5/055 ,  A61B5/7207 ,  G01R33/5608 ,  G01R33/56509

    摘要： For resonance image data of an imaged subject, a method that first detects and estimates the dominant motions of k-space data (i.e., the motion vectors) and then constructs a graphical model for each estimated motion vector. The segments of the k-space that are determined to be corrupted by motion are restored by minimizing the energy associated with the corresponding graphical model. Consequently, the MR image of the imaged subject becomes free of motion artifacts.

    摘要翻译： 对于成像对象的共振图像数据，首先检测并估计k空间数据的主要运动（即，运动矢量），然后为每个估计运动矢量构建图形模型的方法。 通过最小化与相应的图形模型相关联的能量来恢复被确定为被运动破坏的k空间的段。 因此，成像对象的MR图像变得没有运动伪像。

    FEATURE DRIVEN RULE-BASED FRAMEWORK FOR AUTOMATION OF MODELING WORKFLOWS IN DIGITAL MANUFACTURING
    68.
    发明申请
    FEATURE DRIVEN RULE-BASED FRAMEWORK FOR AUTOMATION OF MODELING WORKFLOWS IN DIGITAL MANUFACTURING 有权
    用于数字制造自动化建模工作流程的特征驱动规则框架

    公开(公告)号：US20100094446A1

    公开(公告)日：2010-04-15

    申请号：US12573171

    申请日：2009-10-05

    申请人： Sajjad Baloch ,  Konrad Sickel ,  Vojtech Bubnik ,  Rupen Melkisetoglu ,  Hui Xie ,  Sergei Azernikov ,  Andreas Reh ,  Artem Boltyenkov ,  Fred McBagonluri ,  Tong Fang

    发明人： Sajjad Baloch ,  Konrad Sickel ,  Vojtech Bubnik ,  Rupen Melkisetoglu ,  Hui Xie ,  Sergei Azernikov ,  Andreas Reh ,  Artem Boltyenkov ,  Fred McBagonluri ,  Tong Fang

    IPC分类号： G06F17/50 ,  G06N5/02

    CPC分类号： G06F17/50 ,  G06F2217/06

    摘要： A method for designing a prosthetic device includes acquiring a three-dimensional image of an anatomical surface. A rules script for automatically performing a plurality of image processing rules using a script interpreter is executed. For each particular rule of the plurality of rules, one or more anatomical features that are relevant to the particular rule using a surface shaping engine are determined, the one or more determined anatomical features are automatically segmented from the acquired three-dimensional image using a feature detector, and the particular image processing rule is performed on the acquired three-dimensional image based on the automatically segmented anatomical features using a CAD tool. A prosthetic device design is produced based on the three-dimensional image upon which the rules of the plurality of image processing rules have been performed.

    摘要翻译： 用于设计假体装置的方法包括获取解剖表面的三维图像。 执行用于使用脚本解释器自动执行多个图像处理规则的规则脚本。 对于多个规则的每个特定规则，确定与使用表面整形引擎的特定规则相关的一个或多个解剖特征，使用特征从所获取的三维图像中自动分割一个或多个确定的解剖特征 检测器，并且基于使用CAD工具的自动分割的解剖特征对所获取的三维图像执行特定图像处理规则。 基于已经执行了多个图像处理规则的规则的三维图像来生成假体装置设计。

    Ellipsoidal line cut system and method for hearing aid shell design
    69.
    发明授权
    Ellipsoidal line cut system and method for hearing aid shell design 失效
    用于助听器壳体设计的椭圆线切割系统和方法

    公开(公告)号：US07680634B2

    公开(公告)日：2010-03-16

    申请号：US11538185

    申请日：2006-10-03

    申请人： Artem Boltyenkov ,  Andreas Reh ,  Tong Fang ,  Fred McBagonluri ,  Jörg Bindner

    发明人： Artem Boltyenkov ,  Andreas Reh ,  Tong Fang ,  Fred McBagonluri ,  Jörg Bindner

    IPC分类号： G06F17/50

    CPC分类号： H04R25/658 ,  H04R25/65 ,  H04R25/652 ,  H04R2225/77 ,  Y10T29/49572

    摘要： A system and appertaining algorithm provide a cutting and shaping of the hearing aid shell using an Ellipsoidal Line Cut that increases the speed of detailing operations and enables a creation of more cosmetically appealing shells. A contour algorithm determines a projected contour on the bottom cut plane that corresponds in shape to a portion of the line cut plane contour, and a merger algorithm defines a line cut surface between the portion of the line cut plane contour and the projected contour. An elimination algorithm eliminates parts of the new hearing aid shell design that extend beyond boundaries defined by the original hearing aid shell design.

    摘要翻译： 系统和附加算法提供了使用椭球线切割的助听器外壳的切割和成形，其提高了细节操作的速度，并且能够创建更美观的外壳。 轮廓算法确定底部切割平面上的投影轮廓，其形状对应于线切割平面轮廓的一部分，并且合并算法定义线切割平面轮廓的部分与投影轮廓之间的线切割表面。 消除算法消除了新的助听器外壳设计的部分，超出了原始助听器外壳设计所界定的界限。