公开(公告)号：US07064837B2

公开(公告)日：2006-06-20

申请号：US10120518

申请日：2002-04-12

申请人： Nobufumi Mori ,  Katsumi Hayashi ,  Masayuki Naya ,  Nobuhiko Ogura ,  Yoshiyuki Kunuki

发明人： Nobufumi Mori ,  Katsumi Hayashi ,  Masayuki Naya ,  Nobuhiko Ogura ,  Yoshiyuki Kunuki

IPC分类号： G01N21/55 ,  G01N1/10

CPC分类号： G01N21/553

摘要： Disclosed herein is a sensor utilizing attenuated total reflection. The sensor is constructed of a measuring chip, an optical system, and a measuring section. The measuring chip is equipped with a dielectric block, a thin film layer formed on the dielectric block, and a liquid-sample holding portion for holding a liquid sample. The optical system is used to make a light beam enter the dielectric block at various angles of incidence so that a total internal reflection condition is satisfied at an interface between the dielectric block and the thin film layer. The measuring section measures the state of attenuated total reflection, based on the intensity of the light beam totally reflected at the interface. The liquid-sample holding portion has an opening at its top surface. The sensor further has a lid supply mechanism for placing a lid on the opening to prevent evaporation of the liquid sample.

摘要翻译： 这里公开了一种利用衰减全反射的传感器。 传感器由测量芯片，光学系统和测量部分构成。 测量芯片配备有介质块，形成在介质块上的薄膜层和用于保持液体样品的液体样品保持部分。 光学系统用于使光束以不同的入射角进入介质块，使得在介电块和薄膜层之间的界面处满足全内反射条件。 测量部分根据在界面全反射的光束的强度来测量衰减全反射的状态。 液体样品保持部分在其顶表面上具有开口。 传感器还具有用于将盖放置在开口上以防止液体样品蒸发的盖供给机构。

公开(公告)号：US07062311B1

公开(公告)日：2006-06-13

申请号：US09611229

申请日：2000-07-06

申请人： Tomonari Sendai ,  Katsumi Hayashi ,  Kazuo Hakamata ,  Toshiro Hayakawa ,  Yoji Okazaki ,  Kenji Matsumoto

发明人： Tomonari Sendai ,  Katsumi Hayashi ,  Kazuo Hakamata ,  Toshiro Hayakawa ,  Yoji Okazaki ,  Kenji Matsumoto

IPC分类号： A61B6/00

CPC分类号： G01N21/6456 ,  A61B5/0071 ,  A61B5/0084 ,  G01N21/645 ,  G01N2021/6421 ,  G01N2201/0612

摘要： A fluorescence observing apparatus including a light source for emitting excitation light, an excitation light irradiation section for irradiating the excitation light to a sample, and a fluorescence measurement section for measuring fluorescence emitted from the sample by the irradiation of the excitation light. In the fluorescence observing apparatus, a GaN semiconductor laser is employed as the light source.

摘要翻译： 包括用于发射激发光的光源的荧光观察装置，用于将激发光照射到样品的激发光照射部分和用于通过照射激发光来测量从样品发射的荧光的荧光测量部分。 在荧光观察装置中，使用GaN半导体激光器作为光源。

公开(公告)号：US20050200853A1

公开(公告)日：2005-09-15

申请号：US11077159

申请日：2005-03-11

申请人： Nobufumi Mori ,  Katsumi Hayashi

发明人： Nobufumi Mori ,  Katsumi Hayashi

IPC分类号： G01N21/05 ,  G01N21/11 ,  G01N21/27 ,  G01N21/41 ,  G01N21/77 ,  G01N21/55

CPC分类号： G01N21/7703 ,  G01N21/553

摘要： An analysis chip comprises a thin film layer, which is formed on a dielectric material block and has two different regions. A flow path unit comprising a supply path for supplying a sample onto the thin film layer and a discharging path for discharging the sample is releasably loaded into the analysis chip. A light beam is irradiated to a first interface between one region of the thin film layer and the dielectric material block, and a second interface between the other region of the thin film layer and the dielectric material block, in a parallel manner. Refractive index information with regard to a substance to be analyzed, which is located on the thin film layer, is acquired from intensities of the light beam totally reflected from the first interface and the light beam totally reflected from the second interface.

摘要翻译： 分析芯片包括形成在电介质材料块上并具有两个不同区域的薄膜层。 包括用于将样品供应到薄膜层上的供应路径和用于排出样品的排出路径的流路单元可释放地装载到分析芯片中。 平行地将光束照射到薄膜层的一个区域和电介质材料块之间的第一界面，以及薄膜层的另一个区域和电介质材料块之间的第二界面。 从位于薄膜层上的待分析物质的折射率信息是从第一界面全反射的光束和从第二界面全反射的光束的强度获得的。

公开(公告)号：US06804549B2

公开(公告)日：2004-10-12

申请号：US09841729

申请日：2001-04-25

申请人： Katsumi Hayashi

发明人： Katsumi Hayashi

IPC分类号： A61B600

CPC分类号： A61K49/0034 ,  A61B1/043 ,  A61B5/0071 ,  A61B5/0086 ,  A61B5/418

摘要： A method and system by which the sentinel lymph node, which is the first lymph node to which cancer is transferred when cancer is transferred to lymph nodes, is detected easily and with a high degree of accuracy. A fluorescent colorant is injected near a tumor, and after a predetermined period of time an abdominal operation is performed and stimulating light is projected onto the area being examined. Because the fluorescent colorant has been accumulated on the sentinel lymph node, it emits fluorescent light, which is then magnified and converted to a visual image. The examiner can view the normal image and the visible image at the same time. Because the stimulating light is in the near-infrared wavelength band, which is difficult for the fatty and other tissue that cover the sentinel lymph node to absorb, the sentinel lymph node is detected from the surface of the tissue.

摘要翻译： 当癌症转移至淋巴结时癌细胞转移的第一淋巴结的前哨淋巴结容易且准确度高的方法和系统。 在肿瘤附近注入荧光着色剂，经过规定的时间后进行腹部手术，将刺激光投射到被检查的区域上。 因为荧光着色剂已经积聚在前哨淋巴结上，所以它发出荧光，然后放大并转换为视觉图像。 审查员可以同时查看正常图像和可见图像。 由于刺激光在覆盖前哨淋巴结的脂肪等组织难以吸收的近红外波长带中，所以从组织表面检测前哨淋巴结。

公开(公告)号：US06686085B1

公开(公告)日：2004-02-03

申请号：US09656910

申请日：2000-09-07

申请人： Yosuke Fujii ,  Noriaki Osao ,  Yoshinori Wariishi ,  Takaki Nakagawa ,  Hiroshi Shinkai ,  Katsumi Hayashi

发明人： Yosuke Fujii ,  Noriaki Osao ,  Yoshinori Wariishi ,  Takaki Nakagawa ,  Hiroshi Shinkai ,  Katsumi Hayashi

IPC分类号： H01M804

CPC分类号： H01M8/0271 ,  H01M8/0263 ,  H01M8/04029 ,  H01M8/241 ,  H01M8/2483

摘要： A fuel gas inlet is provided at an outer circumferential edge portion of a second separator. First fuel gas flow passage grooves for supplying a fuel gas to an anode electrode are formed on a side of a surface of the second separator. First fuel gas connecting flow passages, which make communication between the fuel gas inlet and the first fuel gas flow passage grooves, include flow passage lo grooves which are provided on a side of a surface, and through-holes which penetrate through the second separator to make communication with the first fuel gas flow passage grooves. Accordingly, excellent sealing performance is ensured with a simple structure, and it is possible to realize a thin-walled fuel cell.

摘要翻译： 燃料气体入口设置在第二分离器的外周边缘部分。 在第二分离器的表面的一侧形成用于向阳极电极供给燃料气体的第一燃料气体流路。 使燃料气体入口和第一燃料气体流路槽之间的连通的第一燃料气体连通流路包括设置在表面一侧的流路槽，贯通第二隔板的通孔， 与第一燃料气体流通槽沟通。 因此，通过简单的结构确保优异的密封性能，并且可以实现薄壁燃料电池。

公开(公告)号：US5833617A

公开(公告)日：1998-11-10

申请号：US812770

申请日：1997-03-06

申请人： Katsumi Hayashi

发明人： Katsumi Hayashi

IPC分类号： A61B1/00 ,  A61B1/04 ,  A61B5/00 ,  G01J3/44 ,  A61B6/08 ,  G01J3/30

CPC分类号： G01J3/4406 ,  A61B1/00009 ,  A61B1/00186 ,  A61B1/043 ,  A61B1/0638 ,  A61B5/0071 ,  A61B5/0084 ,  A61B1/0646

摘要： A region of interest in a living body is exposed to excitation light, which causes it to produce fluorescence. The fluorescence is separated with respect to desired wavelength ranges and detected. A first detector detects an entire fluorescence component or a fluorescence sum component, which is the sum of a fluorescence component of a comparatively short wavelength region and a fluorescence component of a comparatively long wavelength region. A second detector detects a fluorescence component of a comparatively long wavelength region or a fluorescence difference component, which is the difference between a fluorescence component of a comparatively short wavelength region and a fluorescence component of a comparatively long wavelength region. The output from the first detector and the output from the second detector are divided by each other. The fluorescence intensity depending upon the distance with respect to the region of interest is thus corrected such that no error may occur in making an operation.

公开(公告)号：US5298373A

公开(公告)日：1994-03-29

申请号：US803039

申请日：1991-12-06

申请人： Senzo Sasaoka ,  Katsumi Hayashi ,  Kota Fukui ,  Tetsuro Kojima

发明人： Senzo Sasaoka ,  Katsumi Hayashi ,  Kota Fukui ,  Tetsuro Kojima

IPC分类号： G03C5/29 ,  G03C5/38 ,  G03C5/18 ,  G03C1/76 ,  G03C5/26

CPC分类号： G03C5/38 ,  Y10S430/14

摘要： Silver halide black-and-white photosensitive material is processed with a fixer which contains 0.5 to 2.0 mol/liter of a thiosulfate and 0.003 to 0.3 mol/liter of a meso-ionic compound, the moles of the meso-ionic compound divided by the moles of the thiosulfate being from 0.003 to 0.2. The fixer accelerates fixing speed, enabling rapid processing of photographic material.

摘要翻译： 卤化银黑白感光材料用含有0.5-2.0mol / l硫代硫酸盐和0.003-0.3mol /升内消旋离子化合物的定影剂加工，内消旋体化合物的摩尔数除以 硫代硫酸盐的摩尔数为0.003至0.2。 定影剂加速定影速度，可以快速处理照相材料。

公开(公告)号：US5288596A

公开(公告)日：1994-02-22

申请号：US913628

申请日：1992-07-16

申请人： Katsumi Hayashi

发明人： Katsumi Hayashi

IPC分类号： G03C1/485 ,  G03C5/305 ,  G03C5/50

CPC分类号： G03C1/48538 ,  G03C5/305

摘要： A black and white direct positive image forming process is disclosed. The process comprises imagewise exposing to light a silver halide light sensitive material and developing the material with a black and white developing solution. The light-sensitive material comprises a non-pre-fogged internal latent image type silver halide emulsion layer provided on a support. The material further contains a quaternary salt nucleating agent and a nucleating accelerator. In the present invention, the black and white developing solution contains an imidazole compound and a benzotriazole compound. The amount of the benzotriazole compound is preferably in the range of 0.1 to 10 wt.% of the amount of the imidazole compound. The black and white direct positive image is preferably formed on a computer output microfilm (COM).

摘要翻译： 公开了一种黑白直接正成像方法。 该方法包括将卤化银感光材料成像曝光，并用黑白显影液显影材料。 感光材料包括设置在载体上的非预雾化的内部潜像型卤化银乳剂层。 该材料还含有季盐成核剂和成核促进剂。 在本发明中，黑白显影液含有咪唑化合物和苯并三唑化合物。 苯并三唑化合物的量优选为咪唑化合物的量的0.1〜10重量％。 黑白直接正像优选形成在计算机输出微缩胶片（COM）上。

公开(公告)号：US5204230A

公开(公告)日：1993-04-20

申请号：US706693

申请日：1991-05-29

申请人： Katsumi Hayashi

发明人： Katsumi Hayashi

IPC分类号： G03C5/26 ,  G03C5/30 ,  G03D13/02

CPC分类号： G03C5/267

摘要： A vacuum package of a photographic processing composition consisting of a plurality of components is obtained by placing the components in a bag as separate solid state layers in a vacuum sealed manner. A normally liquid component is converted into a solid adduct in order to form a layer. A substantially water insoluble component or trace component is coated on the surface of particles of a water soluble inorganic compound, from which another layer is formed. The packaged composition is taken out of the bag and diluted with water to prepare a processing solution.

摘要翻译： 通过以真空密封的方式将组分作为分离的固态层放置在袋中来获得由多个组分组成的照相处理组合物的真空包装。 将正常液体的组分转化为固体加合物以形成一层。 基本上不溶于水的组分或痕量组分涂覆在水溶性无机化合物的颗粒表面上，形成另一层。 将包装的组合物从袋中取出并用水稀释以制备处理溶液。

公开(公告)号：US5017463A

公开(公告)日：1991-05-21

申请号：US421037

申请日：1989-10-13

申请人： Nobuaki Inoue ,  Katsumi Hayashi

发明人： Nobuaki Inoue ,  Katsumi Hayashi

IPC分类号： G03C5/38 ,  G03C1/005 ,  G03C1/035 ,  G03C5/26 ,  G03C5/395

CPC分类号： G03C1/005 ,  G03C1/035 ,  G03C5/26 ,  G03C2001/03517 ,  G03C5/164 ,  Y10S430/145 ,  Y10S430/164

摘要： A process for developing a silver halide photographic material having, on a support, at least one silver halide emulsion layer comprising a silver halide emulsion spectrally sensitized by an infrared-sensitizing dye, which is subjected to image-wise exposure, then development and fixing processing and then washing or stabilization processing, wherein the silver halide in the silver halide emulsion layer contains 90 mol % or more of silver chloride, the swelling rate for hydrophilic colloid layers containing the silver halide emulsion layer is 150% or less, and the replenishment in the washing or stabilization processing is 1,200 ml or less per square meter of the photographic material.

摘要翻译： 一种用于显影卤化银照相材料的方法，该方法在支持体上具有至少一个卤化银乳剂层，该卤化银乳剂层包含经受成像曝光的红外线感光染料光谱敏化的卤化银乳剂，然后显影和定影处理 然后进行洗涤或稳定化处理，其中，卤化银乳剂层中的卤化银含有90mol％以上的氯化银，含有卤化银乳剂层的亲水性胶体层的溶胀率为150％以下，补充量为 洗涤或稳定处理是每平方米照相材料1200毫升或更少。